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ONTOLOGY REPORT - ANNOTATIONS


Term:Transplant Rejection
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Accession:DOID:9004283 term browser browse the term
Definition:A process in which a transplant recipient's immune system attacks the transplanted organ or tissue. The rejection can be hyperacute (occurring within a few minutes), acute (occurring within days to months), or chronic (occurring over many years).
Synonyms:primary_id: RDO:9000019
For additional species annotation, visit the Alliance of Genome Resources.


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Transplant Rejection term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoa1 apolipoprotein A1 JBrowse link 8 50,525,091 50,526,875 RGD:7241209
G Arrb1 arrestin, beta 1 JBrowse link 1 164,502,099 164,573,947 RGD:13506894
G Arrb2 arrestin, beta 2 JBrowse link 10 57,040,252 57,048,045 RGD:13506894
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:8548879
RGD:8657367
G Ccl3 C-C motif chemokine ligand 3 JBrowse link 10 70,869,516 70,871,066 RGD:7241797
G Ccr2 C-C motif chemokine receptor 2 RGD:8657367
G Ccr5 C-C motif chemokine receptor 5 JBrowse link 8 133,192,398 133,215,599 RGD:8552228
RGD:8552231
G Cd274 CD274 molecule JBrowse link 1 247,519,890 247,539,659 RGD:8657367
G Cd4 Cd4 molecule JBrowse link 4 157,381,862 157,408,357 RGD:10058956
RGD:10058974
G Cd40 CD40 molecule JBrowse link 3 161,519,789 161,534,943 RGD:7248441
RGD:8547788
RGD:7248755
G Cd40lg CD40 ligand JBrowse link X 159,703,703 159,714,886 RGD:7248420
RGD:8547783
RGD:7248719
RGD:7248598
G Col1a2 collagen type I alpha 2 chain JBrowse link 4 31,534,225 31,569,152 RGD:7248773
G Col3a1 collagen type III alpha 1 chain JBrowse link 9 52,023,295 52,059,221 RGD:7248773
G Csf1 colony stimulating factor 1 JBrowse link 2 210,522,370 210,550,546 RGD:7257570
RGD:7257590
G Csf3 colony stimulating factor 3 JBrowse link 10 86,616,785 86,619,160 RGD:11039422
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 JBrowse link 9 67,699,397 67,706,068 RGD:7204515
RGD:7204516
RGD:7204518
RGD:7204671
RGD:7204678
G Cxcr1 C-X-C motif chemokine receptor 1 JBrowse link 9 81,466,430 81,469,299 RGD:7257676
G Cxcr2 C-X-C motif chemokine receptor 2 JBrowse link 9 81,427,275 81,435,065 RGD:7257683
RGD:7257690
G Dhodh dihydroorotate dehydrogenase (quinone) JBrowse link 19 42,066,103 42,087,906 RGD:11040447
G Ece1 endothelin converting enzyme 1 JBrowse link 5 156,215,469 156,318,652 RGD:7244165
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 JBrowse link 1 259,692,020 259,818,922 RGD:9685445
G Fcgr2a Fc fragment of IgG receptor IIa JBrowse link 13 91,146,878 91,163,691 RGD:9588604
G Gfer growth factor, augmenter of liver regeneration JBrowse link 10 14,059,347 14,061,703 RGD:9685732
G Got2 glutamic-oxaloacetic transaminase 2 JBrowse link 19 9,587,637 9,613,323 RGD:13504864
G Gstt1 glutathione S-transferase theta 1 JBrowse link 20 13,799,102 13,816,527 RGD:10450792
G Havcr1 hepatitis A virus cellular receptor 1 JBrowse link 10 31,813,819 31,860,934 RGD:7244382
G Havcr2 hepatitis A virus cellular receptor 2 JBrowse link 10 31,561,838 31,590,624 RGD:7245954
RGD:9686116
G Hspd1 heat shock protein family D member 1 JBrowse link 9 61,680,529 61,691,202 RGD:12910541
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:7364833
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta JBrowse link 16 74,177,233 74,230,809 RGD:7495769
RGD:4892204
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:7364833
RGD:11049523
RGD:7364994
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:8549629
RGD:10402939
RGD:8549647
G Il15 interleukin 15 JBrowse link 19 23,542,606 23,624,366 RGD:10402939
G Il17a interleukin 17A JBrowse link 9 26,841,299 26,844,786 RGD:9068426
RGD:9068938
RGD:4781440
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:8655943
G Il18bp interleukin 18 binding protein JBrowse link 1 167,091,521 167,095,727 RGD:8655943
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:7175098
RGD:7401188
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:8549799
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:7364833
RGD:10047078
RGD:8662936
G Il5 interleukin 5 JBrowse link 10 39,066,716 39,069,587 RGD:11354977
G Il7 interleukin 7 JBrowse link 2 96,427,884 96,474,979 RGD:10402939
G Itga4 integrin subunit alpha 4 JBrowse link 3 66,178,745 66,265,547 RGD:9698437
G Kdr kinase insert domain receptor JBrowse link 14 34,727,677 34,787,127 RGD:8549738
G Kit KIT proto-oncogene receptor tyrosine kinase JBrowse link 14 35,072,131 35,149,638 RGD:12910749
G Klrk1 killer cell lectin like receptor K1 JBrowse link 4 163,392,652 163,403,735 RGD:9685184
G Lta lymphotoxin alpha JBrowse link 20 4,851,889 4,854,677 RGD:8548835
RGD:8548836
G Mmp3 matrix metallopeptidase 3 JBrowse link 8 5,676,608 5,698,579 RGD:7241226
G Muc2 mucin 2, oligomeric mucus/gel-forming JBrowse link 1 214,663,929 214,693,197 RGD:7349372
G Muc4 mucin 4, cell surface associated JBrowse link 11 71,242,973 71,285,217 RGD:7349372
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:7240566
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:10413870
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:13504718
G Nppa natriuretic peptide A JBrowse link 5 164,808,407 164,809,716 RGD:7297054
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 31,728,373 32,704,022 RGD:7174721
G Pdcd1 programmed cell death 1 JBrowse link 9 101,305,742 101,319,937 RGD:7248673
RGD:9589063
RGD:9589060
G Pdgfd platelet derived growth factor D JBrowse link 8 4,441,010 4,666,754 RGD:9854642
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:1625382
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 JBrowse link 8 21,669,236 21,680,615 RGD:8693431
G Plat plasminogen activator, tissue type JBrowse link 16 74,098,263 74,122,897 RGD:11541079
G Plau plasminogen activator, urokinase JBrowse link 15 3,644,296 3,650,765 RGD:7241140
G Psmb9 proteasome subunit beta 9 JBrowse link 20 3,973,424 3,978,845 RGD:9854627
G Raet1l retinoic acid early transcript 1L JBrowse link 7 114,233,896 114,234,243 RGD:9685184
G Rapgef3 Rap guanine nucleotide exchange factor 3 JBrowse link 7 139,232,263 139,254,668 RGD:9835362
G Relb RELB proto-oncogene, NF-kB subunit JBrowse link 1 80,517,081 80,545,019 RGD:7777161
G Rrlt similar to retinoic acid early transcript 1L JBrowse link 1 1,437,716 1,442,089 RGD:9685184
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:7421554
G RT1-CE13 RT1 class I, locus CE13 RGD:7387273
G Sell selectin L JBrowse link 13 82,369,820 82,387,774 RGD:7175511
G Slc5a7 solute carrier family 5 member 7 JBrowse link 9 5,294,377 5,330,822 RGD:9999387
G Spi1 Spi-1 proto-oncogene JBrowse link 3 79,918,127 79,937,708 RGD:9586451
G Stat4 signal transducer and activator of transcription 4 JBrowse link 9 54,340,649 54,457,753 RGD:7207871
G Tbxa2r thromboxane A2 receptor JBrowse link 7 11,253,153 11,259,233 RGD:11059606
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:7207901
RGD:7240555
RGD:7240554
RGD:7240551
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:7240548
RGD:7240555
G Tlr9 toll-like receptor 9 JBrowse link 8 114,916,122 114,920,171 RGD:7246885
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:7394793
RGD:8548836
RGD:7401188
G Tnfrsf1b TNF receptor superfamily member 1B JBrowse link 5 163,136,390 163,167,299 RGD:7245520
G Tpmt thiopurine S-methyltransferase JBrowse link 17 18,029,090 18,047,716 RGD:11038722
G Tpo thyroid peroxidase JBrowse link 6 49,020,918 49,089,855 RGD:7207487
G Xdh xanthine dehydrogenase JBrowse link 6 25,149,570 25,211,273 RGD:13209011
Cardiac Allograft Vasculopathy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:11341701
G Pdgfd platelet derived growth factor D JBrowse link 8 4,441,010 4,666,754 RGD:9854642
Chronic Allograft Dysfunction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:7245568
RGD:8695995
G C3 complement C3 JBrowse link 9 9,721,137 9,747,084 RGD:11040803
G Cd40 CD40 molecule JBrowse link 3 161,519,789 161,534,943 RGD:11352297
G Cd40lg CD40 ligand JBrowse link X 159,703,703 159,714,886 RGD:11352297
G F7 coagulation factor VII JBrowse link 16 81,824,610 81,834,923 RGD:11049508
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:7245568
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:10041002
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:10450586
Chronic Allograft Nephropathy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aco1 aconitase 1 JBrowse link 5 56,425,076 56,481,218 RGD:11541086
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:11035281
G Ccl3 C-C motif chemokine ligand 3 JBrowse link 10 70,869,516 70,871,066 RGD:7241819
G Clu clusterin JBrowse link 15 42,626,612 42,665,858 RGD:9068431
G Mmp3 matrix metallopeptidase 3 JBrowse link 8 5,676,608 5,698,579 RGD:7241226
G Mmp7 matrix metallopeptidase 7 JBrowse link 8 5,893,253 5,900,965 RGD:9685339
G Pdgfa platelet derived growth factor subunit A JBrowse link 12 17,734,141 17,756,186 RGD:11080974
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:10449491
RGD:11080974
G Pdgfra platelet derived growth factor receptor alpha JBrowse link 14 35,527,926 35,581,130 RGD:11080974
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:11080974
G Plau plasminogen activator, urokinase JBrowse link 15 3,644,296 3,650,765 RGD:7241259
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:13208600
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:13208600
RGD:13208601
Chronic Lung Allograft Dysfunction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Epas1 endothelial PAS domain protein 1 JBrowse link 6 10,306,508 10,385,239 RGD:10395369
Corneal Graft Rejection term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd4 Cd4 molecule JBrowse link 4 157,381,862 157,408,357 RGD:10059315
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:9684950
Primary Graft Dysfunction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd40lg CD40 ligand JBrowse link X 159,703,703 159,714,886 RGD:7248713
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:8547722
RGD:11520779
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:11049478
G Npy neuropeptide Y JBrowse link 4 79,557,856 79,565,059 RGD:10448956

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14042
    disease of anatomical entity 13255
      immune system disease 2381
        Transplant Rejection 98
          Chronic Allograft Dysfunction + 24
          Corneal Graft Rejection 2
          Primary Graft Dysfunction 4
Path 2
Term Annotations click to browse term
  disease 14042
    disease of anatomical entity 13255
      Immune & Inflammatory Diseases 2939
        immune system disease 2381
          Transplant Rejection 98
            Chronic Allograft Dysfunction + 24
            Corneal Graft Rejection 2
            Primary Graft Dysfunction 4
paths to the root