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Accession:CHEBI:101085 term browser browse the term
Definition:A sulfonamide that is benzene-1,3-disulfonamide in which the hydrogens at positions 4 and 5 are substituted by chlorine. An oral carbonic anhydrase inhibitor, it partially suppresses the secretion (inflow) of aqueous humor in the eye and so reduces intraocular pressure. It is used for the treatment of glaucoma.
Synonyms:related_synonym: 1,3-disulfamoyl-4,5-dichlorobenzene;   1,3-disulfamyl-4,5-dichlorobenzene;   3,4-dichloro-5-sulfamylbenzenesulfonamide;   4,5-DICHLOROBENZENE-1,3-DISULFONAMIDE;   4,5-dichloro-1,3-benzenedisulfonamide;   4,5-dichloro-1,3-disulfamoylbenzene;   4,5-dichloro-benzene-1,3-disulfonic acid diamide;   4,5-dichloro-m-benzenedisulfonamide;   DICHLORPHENAMIDE;   Dichlorophenamide;   Formula=C6H6Cl2N2O4S2;   InChI=1S/C6H6Cl2N2O4S2/c7-4-1-3(15(9,11)12)2-5(6(4)8)16(10,13)14/h1-2H,(H2,9,11,12)(H2,10,13,14);   InChIKey=GJQPMPFPNINLKP-UHFFFAOYSA-N;   SMILES=NS(=O)(=O)c1cc(Cl)c(Cl)c(c1)S(N)(=O)=O;   dichlofenamide;   diclofenamida;   diclofenamidum
 alt_id: CHEBI:4505;   CHEBI:47477
 xref: Beilstein:2703329 "Beilstein";   CAS:120-97-8 "ChemIDplus";   CAS:120-97-8 "KEGG COMPOUND";   CAS:120-97-8 "NIST Chemistry WebBook";   DrugBank:DB01144;   Drug_Central:864 "DrugCentral";   KEGG:C07459;   KEGG:D00518;   LINCS:LSM-3602
 xref_mesh: MESH:D004005
 xref: PDBeChem:I7A;   Patent:US2835702;   Wikipedia:Dichlorphenamide

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diclofenamide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ca3 carbonic anhydrase 3 JBrowse link 2 88,126,519 88,136,063 RGD:6480464
G Car2 carbonic anhydrase 2 JBrowse link 2 88,097,740 88,112,868 RGD:6480464

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  CHEBI ontology 19741
    role 19688
      application 19339
        pharmaceutical 19214
          drug 19214
            ophthalmology drug 391
              diclofenamide 2
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Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    p-block element atom 19622
                      carbon group element atom 19515
                        carbon atom 19508
                          organic molecular entity 19508
                            organic molecule 19431
                              organic cyclic compound 19197
                                carbocyclic compound 17533
                                  benzenoid aromatic compound 17060
                                    benzenes 16778
                                      chlorobenzenes 12670
                                        dichlorobenzene 9741
                                          diclofenamide 2
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