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ONTOLOGY REPORT - ANNOTATIONS


Term:zolmitriptan
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Accession:CHEBI:10124 term browser browse the term
Definition:A member of the class of tryptamines that is N,N-dimethyltryptamine in which the hydrogen at position 5 of the indole ring has been replaced by a [(4S)-2-oxo-1,3-oxazolidin-4-yl]methyl group. A serotonin 5-HT1 B and D receptor agonist, it is used for the treatment of migraine.
Synonyms:exact_synonym: (4S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one
 related_synonym: 311C90;   4-[[3-(2-dimethylaminoethyl)-1H-indol-5-yl]methyl]oxazolidin-2-one;   Formula=C16H21N3O2;   InChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1;   InChIKey=ULSDMUVEXKOYBU-ZDUSSCGKSA-N;   SMILES=C1=C2C(=CNC2=CC=C1C[C@@H]3NC(=O)OC3)CCN(C)C;   Zipton;   Zomig;   Zomigoro;   Zominat;   zolmitriptanum
 xref: Beilstein:7415010 "Beilstein";   CAS:139264-17-8 "ChemIDplus";   CAS:139264-17-8 "KEGG COMPOUND";   DrugBank:DB00315;   Drug_Central:2869 "DrugCentral";   KEGG:C07218;   KEGG:D00415;   LINCS:LSM-3208
 xref_mesh: MESH:C089750
 xref: Wikipedia:Zolmitriptan


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zolmitriptan term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bad BCL2-associated agonist of cell death JBrowse link 1 222,198,516 222,207,459 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G Gpt glutamic--pyruvic transaminase JBrowse link 7 117,759,083 117,761,932 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19748
    role 19695
      application 19350
        anti-inflammatory agent 14955
          anti-inflammatory drug 13608
            zolmitriptan 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 19748
    subatomic particle 19744
      composite particle 19744
        hadron 19744
          baryon 19744
            nucleon 19744
              atomic nucleus 19744
                atom 19744
                  main group element atom 19628
                    p-block element atom 19628
                      carbon group element atom 19522
                        carbon atom 19516
                          organic molecular entity 19516
                            organic molecule 19434
                              organic cyclic compound 19201
                                organic heterocyclic compound 18270
                                  organic heteropolycyclic compound 17577
                                    organic heterobicyclic compound 16245
                                      benzopyrrole 9333
                                        indoles 9195
                                          tryptamines 395
                                            tryptamine 393
                                              N,N-dimethyltryptamine 94
                                                zolmitriptan 10
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.