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ONTOLOGY REPORT - ANNOTATIONS


Term:sorbinil
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Accession:CHEBI:102029 term browser browse the term
Definition:An azaspiro compound having a monofluoro-substituted chromane skeleton spiro-linked to an imidazolidinedione ring.
Synonyms:exact_synonym: (4S)-6-fluoro-2,3-dihydro-2'H,5'H-spiro[chromene-4,4'-imidazolidine]-2',5'-dione
 related_synonym: (S)-6-Fluorospiro(chroman-4,4'-imidazolidine)-2',5'-dione;   Formula=C11H9FN2O3;   InChI=1S/C11H9FN2O3/c12-6-1-2-8-7(5-6)11(3-4-17-8)9(15)13-10(16)14-11/h1-2,5H,3-4H2,(H2,13,14,15,16)/t11-/m0/s1;   InChIKey=LXANPKRCLVQAOG-NSHDSACASA-N;   SMILES=Fc1ccc2OCC[C@]3(NC(=O)NC3=O)c2c1;   sorbinilo;   sorbinilum;   sorbinol
 alt_id: CHEBI:45392
 xref: CAS:68367-52-2 "ChemIDplus";   DrugBank:DB02712
 xref_mesh: MESH:C026411
 xref: PDBeChem:SBI;   PMID:10875546 "Europe PMC";   PMID:10933817 "Europe PMC";   PMID:11048957 "Europe PMC";   PMID:11900277 "Europe PMC";   PMID:18772236 "Europe PMC";   PMID:19821053 "Europe PMC";   PMID:20138035 "Europe PMC";   PMID:20308528 "Europe PMC";   PMID:20354121 "Europe PMC";   PMID:21129963 "Europe PMC";   PMID:29438107 "Europe PMC";   PMID:7564101 "Europe PMC";   PMID:7591626 "Europe PMC";   PMID:8159110 "Europe PMC";   PMID:8692029 "Europe PMC";   PMID:9007520 "Europe PMC";   PMID:9088040 "Europe PMC";   PMID:9195881 "Europe PMC";   PMID:9349546 "Europe PMC";   Patent:DE2821966;   Patent:US4130714;   Reaxys:4297401 "Reaxys";   Wikipedia:Sorbinil


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sorbinil term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acta2 actin alpha 2, smooth muscle JBrowse link 1 252,537,614 252,550,394 RGD:6480464
G Akr1b1 aldo-keto reductase family 1 member B JBrowse link 4 61,706,866 61,720,959 RGD:6480464
G Akr1b10 aldo-keto reductase family 1 member B10 JBrowse link 4 61,813,265 61,830,371 RGD:6480464
G Akr1b8 aldo-keto reductase family 1, member B8 JBrowse link 4 61,772,064 61,784,637 RGD:6480464
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:6480464
G Cdh1 cadherin 1 JBrowse link 19 38,768,467 38,838,395 RGD:6480464
G Fn1 fibronectin 1 JBrowse link 9 78,900,111 78,969,018 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Ngf nerve growth factor JBrowse link 2 204,886,158 204,939,523 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Tac1 tachykinin, precursor 1 JBrowse link 4 33,638,853 33,646,819 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19741
    role 19688
      chemical role 19199
        antioxidant 14093
          sorbinil 17
Path 2
Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    p-block element atom 19622
                      carbon group element atom 19515
                        carbon atom 19508
                          organic molecular entity 19508
                            organic molecule 19431
                              organic cyclic compound 19197
                                organic heterocyclic compound 18267
                                  oxacycle 17008
                                    benzopyran 9465
                                      1-benzopyran 9160
                                        chromanes 3918
                                          sorbinil 17
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