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ONTOLOGY REPORT - ANNOTATIONS


Term:methohexital
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Accession:CHEBI:102216 term browser browse the term
Definition:A barbiturate, the structure of which is that of barbituric acid substituted at N-1 by a methyl group and at C-5 by allyl and 1-methylpent-2-ynyl groups.
Synonyms:exact_synonym: 1-methyl-5-(1-methylpent-2-yn-1-yl)-5-(prop-2-en-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione
 related_synonym: (+-)-5-allyl-1-methyl-5-(1-methyl-2-pentynyl)barbituric acid;   5-Allyl-1-methyl-5-(1-methyl-pent-2-ynyl)-pyrimidine-2,4,6-trione;   5-Allyl-5-(3-hexyn-2-yl)-1-methylbarbituric acid;   5-allyl-1-methyl-5-(1-methyl-2-pentynyl)-2,4,6(1H,3H,5H)-pyrimidinetrione;   Formula=C14H18N2O3;   InChI=1S/C14H18N2O3/c1-5-7-8-10(3)14(9-6-2)11(17)15-13(19)16(4)12(14)18/h6,10H,2,5,9H2,1,3-4H3,(H,15,17,19);   InChIKey=NZXKDOXHBHYTKP-UHFFFAOYSA-N;   Methohexitalum;   Methohexitone;   Metohexital;   SMILES=CCC#CC(C)C1(CC=C)C(=O)NC(=O)N(C)C1=O;   alpha-DL-1-methyl-5-allyl-5-(1'-methylpentyn-2-yl)barbituric acid
 alt_id: CHEBI:6833
 xref: Beilstein:89964 "Beilstein";   CAS:151-83-7 "ChemIDplus";   CAS:151-83-7 "KEGG COMPOUND";   CAS:151-83-7 "NIST Chemistry WebBook";   DrugBank:DB00474;   Drug_Central:1748 "DrugCentral";   KEGG:C07844;   KEGG:D04985
 xref_mesh: MESH:D008723
 xref: PMID:13919899 "Europe PMC";   PMID:20045848 "Europe PMC";   PMID:22330701 "Europe PMC";   PMID:22914630 "Europe PMC";   PMID:22914634 "Europe PMC";   PMID:23164727 "Europe PMC";   PMID:23399487 "Europe PMC";   PMID:23422530 "Europe PMC";   PMID:23813116 "Europe PMC";   PMID:3654008 "Europe PMC";   PMID:6864729 "ChEMBL";   Reaxys:89964 "Reaxys";   Wikipedia:Methohexital
 cyclic_relationship: is_conjugate_acid_of CHEBI:60792


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methohexital term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:6480464
G Kras KRAS proto-oncogene, GTPase JBrowse link 4 179,482,562 179,515,483 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Rac1 Rac family small GTPase 1 JBrowse link 12 13,090,316 13,111,841 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19748
    role 19695
      application 19350
        pharmaceutical 19224
          drug 19224
            drug allergen 9763
              methohexital 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19748
    subatomic particle 19744
      composite particle 19744
        hadron 19744
          baryon 19744
            nucleon 19744
              atomic nucleus 19744
                atom 19744
                  main group element atom 19628
                    p-block element atom 19628
                      carbon group element atom 19522
                        carbon atom 19516
                          organic molecular entity 19516
                            organic molecule 19434
                              organic cyclic compound 19201
                                organic heterocyclic compound 18270
                                  organic heteromonocyclic compound 16358
                                    diazines 12135
                                      pyrimidines 11954
                                        pyrimidone 8743
                                          barbiturates 4378
                                            methohexital 5
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.