Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:nomifensine
go back to main search page
Accession:CHEBI:116225 term browser browse the term
Definition:An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.
Synonyms:exact_synonym: 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine
 related_synonym: 2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine;   8-Amino-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline;   D,L-nomifensine;   Formula=C16H18N2;   InChI=1S/C16H18N2/c1-18-10-14(12-6-3-2-4-7-12)13-8-5-9-16(17)15(13)11-18/h2-9,14H,10-11,17H2,1H3;   InChIKey=XXPANQJNYNUNES-UHFFFAOYSA-N;   Nomifenison;   Nomifensin;   Nomiphensine;   R/S-nomifensine;   SMILES=CN1CC(c2ccccc2)c2cccc(N)c2C1;   nomifensina;   nomifensinum
 xref: Beilstein:484561;   CAS:24526-64-5;   DrugBank:DB04821;   Drug_Central:1958;   LINCS:LSM-4388
 xref_mesh: MESH:D009627
 xref: PMID:1502708;   PMID:24766210;   PMID:7189402;   Reaxys:484561


show annotations for term's descendants       view all columns           Sort by:
 
nomifensine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb4 ATP binding cassette subfamily B member 4 JBrowse link 4 22,133,984 22,192,687 RGD:6480464
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6480464
G Slc18a2 solute carrier family 18 member A2 JBrowse link 1 280,397,831 280,457,968 RGD:6480464
G Slc6a3 solute carrier family 6 member 3 JBrowse link 1 32,323,011 32,363,983 RGD:6480464
G Slc6a4 solute carrier family 6 member 4 JBrowse link 10 63,153,656 63,188,377 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19790
    role 19738
      biological role 19737
        pharmacological role 18817
          neurotransmitter agent 16444
            dopaminergic agent 5078
              dopamine uptake inhibitor 4552
                nomifensine 5
                  (R)-nomifensine 0
                  (S)-nomifensine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19790
    subatomic particle 19788
      composite particle 19788
        hadron 19788
          baryon 19788
            nucleon 19788
              atomic nucleus 19788
                atom 19788
                  main group element atom 19674
                    p-block element atom 19674
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic molecule 19483
                              organic cyclic compound 19246
                                organic heterocyclic compound 18366
                                  organonitrogen heterocyclic compound 17259
                                    isoquinolines 426
                                      nomifensine 5
                                        (R)-nomifensine 0
                                        (S)-nomifensine 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.