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Accession:CHEBI:116735 term browser browse the term
Definition:A benzoate ester having 4-aminobenzoic acid as the acid component and ethanol as the alcohol component. A surface anaesthetic, it is used to suppress the gag reflex, and as a lubricant and topical anaesthetic on the larynx, mouth, nasal cavity, respiratory tract, oesophagus, rectum, urinary tract, and vagina.
Synonyms:exact_synonym: ethyl 4-aminobenzoate
 related_synonym: 4-aminobenzoic acid ethyl ester;   Amben ethyl ester;   Benzocaina;   Benzocainum;   Ethyl aminobenzoate;   Ethyl p-aminobenzoate;   Ethyl p-aminophenylcarboxylate;   Formula=C9H11NO2;   InChI=1S/C9H11NO2/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6H,2,10H2,1H3;   InChIKey=BLFLLBZGZJTVJG-UHFFFAOYSA-N;   SMILES=CCOC(=O)c1ccc(N)cc1;   p-(Ethoxycarbonyl)aniline;   p-Carbethoxyaniline;   p-Ethoxycarboxylic aniline
 alt_id: CHEBI:3030
 xref: Beilstein:638434 "Beilstein";   CAS:94-09-7 "ChemIDplus";   CAS:94-09-7 "KEGG COMPOUND";   CAS:94-09-7 "NIST Chemistry WebBook";   DrugBank:DB01086;   Drug_Central:323 "DrugCentral";   HMDB:HMDB0004992;   KEGG:C07527;   KEGG:D00552;   LINCS:LSM-5830
 xref_mesh: MESH:D001566
 xref: PMID:10866370 "ChEMBL";   PMID:1155304 "Europe PMC";   PMID:12574744 "Europe PMC";   PMID:12873507 "ChEMBL";   PMID:16640711 "Europe PMC";   PMID:18971079 "Europe PMC";   PMID:21616561 "Europe PMC";   PMID:22015737 "Europe PMC";   PMID:22105694 "Europe PMC";   PMID:22551703 "Europe PMC";   PMID:22556388 "Europe PMC";   PMID:23301559 "Europe PMC";   PMID:23565580 "Europe PMC";   PMID:23696166 "Europe PMC";   PMID:25097477 "Europe PMC";   PMID:2579237 "ChEMBL";   PMID:29079364 "Europe PMC";   Reaxys:638434 "Reaxys";   Wikipedia:Benzocaine

show annotations for term's descendants       view all columns           Sort by:
benzocaine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl4 C-C motif chemokine ligand 4 JBrowse link 10 70,870,926 70,886,357 RGD:6480464
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:6480464
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:6480464
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:6480464
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:6480464
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19754
    role 19701
      biological role 19700
        aetiopathogenetic role 18813
          sensitiser 9303
            benzocaine 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19754
    subatomic particle 19752
      composite particle 19752
        hadron 19752
          baryon 19752
            nucleon 19752
              atomic nucleus 19752
                atom 19752
                  main group element atom 19637
                    p-block element atom 19637
                      carbon group element atom 19528
                        carbon atom 19517
                          organic molecular entity 19517
                            organic group 18422
                              organic divalent group 18414
                                organodiyl group 18414
                                  carbonyl group 18303
                                    carbonyl compound 18303
                                      carboxylic acid 17971
                                        aromatic carboxylic acid 10750
                                          benzoic acids 10716
                                            benzoate ester 4003
                                              benzocaine 6
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.