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ONTOLOGY REPORT - ANNOTATIONS


Term:2-nitrofluorene
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Accession:CHEBI:1224 term browser browse the term
Definition:A nitroarene that is fluorene substituted by a nitro group at position 2.
Synonyms:exact_synonym: 2-nitro-9H-fluorene
 related_synonym: Formula=C13H9NO2;   InChI=1S/C13H9NO2/c15-14(16)11-5-6-13-10(8-11)7-9-3-1-2-4-12(9)13/h1-6,8H,7H2;   InChIKey=XFOHWECQTFIEIX-UHFFFAOYSA-N;   NF;   Nitrofluorene;   SMILES=[O-][N+](=O)c1ccc-2c(Cc3ccccc-23)c1
 xref: Beilstein:1877983 "Beilstein";   CAS:607-57-8 "ChemIDplus";   CAS:607-57-8 "KEGG COMPOUND";   CAS:607-57-8 "NIST Chemistry WebBook";   KEGG:C10923;   LINCS:LSM-37230
 xref_mesh: MESH:C019499
 xref: PMID:10366768 "Europe PMC";   PMID:23128813 "Europe PMC";   Reaxys:1877983 "Reaxys";   Wikipedia:2-Nitrofluorene


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2-nitrofluorene term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:6480464
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B JBrowse link 4 22,225,123 22,307,577 RGD:6480464
G Abcc3 ATP binding cassette subfamily C member 3 JBrowse link 10 82,047,308 82,116,928 RGD:6480464
G Aco1 aconitase 1 JBrowse link 5 56,425,076 56,481,218 RGD:6480464
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:6480464
G Aif1 allograft inflammatory factor 1 JBrowse link 20 5,161,350 5,167,176 RGD:6480464
G Akr7a3 aldo-keto reductase family 7 member A3 JBrowse link 5 157,801,120 157,813,756 RGD:6480464
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 JBrowse link 1 238,222,689 238,264,381 RGD:6480464
G Anxa2 annexin A2 JBrowse link 8 75,687,134 75,723,589 RGD:6480464
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 JBrowse link 15 27,849,943 27,852,083 RGD:6480464
G Arpc1b actin related protein 2/3 complex, subunit 1B JBrowse link 12 11,252,300 11,265,849 RGD:6480464
G Atf3 activating transcription factor 3 JBrowse link 13 109,817,892 109,849,632 RGD:6480464
G Atp5mc1 ATP synthase membrane subunit c locus 1 JBrowse link 10 83,895,941 83,898,640 RGD:6480464
G Atp6v1d ATPase H+ transporting V1 subunit D JBrowse link 6 102,032,271 102,047,754 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bhmt betaine-homocysteine S-methyltransferase JBrowse link 2 23,236,573 23,256,158 RGD:6480464
G Btg2 BTG anti-proliferation factor 2 JBrowse link 13 50,913,185 50,916,944 RGD:6480464
G Ccdc86 coiled-coil domain containing 86 JBrowse link 1 226,996,435 227,002,016 RGD:6480464
G Ccnb1 cyclin B1 JBrowse link 2 30,782,133 30,791,106 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:6480464
G Ccng1 cyclin G1 JBrowse link 10 25,903,925 25,910,298 RGD:6480464
G Cct3 chaperonin containing TCP1 subunit 3 JBrowse link 2 187,669,051 187,693,610 RGD:6480464
G Cd1d1 CD1d1 molecule JBrowse link 2 186,330,298 186,333,805 RGD:6480464
G Cd74 CD74 molecule JBrowse link 18 56,071,420 56,080,851 RGD:6480464
G Cdc20 cell division cycle 20 JBrowse link 5 137,260,728 137,264,931 RGD:6480464
G Cdk1 cyclin-dependent kinase 1 JBrowse link 20 20,576,341 20,591,510 RGD:6480464
G Cdk16 cyclin-dependent kinase 16 JBrowse link X 1,707,285 1,718,821 RGD:6480464
G Cdk4 cyclin-dependent kinase 4 JBrowse link 7 70,345,971 70,352,689 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Ces2c carboxylesterase 2C JBrowse link 1 282,640,752 282,648,319 RGD:6480464
G Ces2h carboxylesterase 2H JBrowse link 19 37,052,555 37,067,176 RGD:6480464
G Cgref1 cell growth regulator with EF hand domain 1 JBrowse link 6 26,797,126 26,809,132 RGD:6480464
G Cgrrf1 cell growth regulator with ring finger domain 1 JBrowse link 15 23,619,176 23,639,622 RGD:6480464
G Cr1l complement C3b/C4b receptor 1 like JBrowse link 13 113,824,886 113,872,097 RGD:6480464
G Cryab crystallin, alpha B JBrowse link 8 55,178,543 55,182,546 RGD:6480464
G Cstb cystatin B JBrowse link 20 10,966,357 10,968,399 RGD:6480464
G Ctsd cathepsin D JBrowse link 1 215,541,570 215,553,446 RGD:6480464
G Ctss cathepsin S JBrowse link 2 197,655,780 197,679,768 RGD:6480464
G Cxcl10 C-X-C motif chemokine ligand 10 JBrowse link 14 17,210,733 17,212,930 RGD:6480464
G Cxcl3 chemokine (C-X-C motif) ligand 3 JBrowse link 14 18,820,168 18,839,659 RGD:6480464
G Cyb5r3 cytochrome b5 reductase 3 JBrowse link 7 124,024,003 124,041,564 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 JBrowse link 1 258,709,726 258,766,873 RGD:6480464
G Dcn decorin JBrowse link 7 38,742,250 38,782,282 RGD:6480464
G Ddah1 dimethylarginine dimethylaminohydrolase 1 JBrowse link 2 251,634,368 251,766,009 RGD:6480464
G Ddx21 DExD-box helicase 21 JBrowse link 20 32,213,147 32,232,632 RGD:6480464
G Dkc1 dyskerin pseudouridine synthase 1 JBrowse link X 155,844,914 155,862,363 RGD:6480464
G Dmbt1 deleted in malignant brain tumors 1 JBrowse link 1
1
201,620,642
203,149,414
201,689,905
203,228,705
RGD:6480464
G Dpyd dihydropyrimidine dehydrogenase JBrowse link 2 221,823,692 222,694,627 RGD:6480464
G Dus1l dihydrouridine synthase 1-like JBrowse link 10 109,972,018 109,979,113 RGD:6480464
G Dusp6 dual specificity phosphatase 6 JBrowse link 7 41,475,163 41,479,393 RGD:6480464
G Dut deoxyuridine triphosphatase JBrowse link 3 117,514,399 117,525,450 RGD:6480464
G Eef1g eukaryotic translation elongation factor 1 gamma JBrowse link 1 225,163,391 225,173,997 RGD:6480464
G Eef2 eukaryotic translation elongation factor 2 JBrowse link 7 11,401,501 11,406,771 RGD:6480464
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 JBrowse link 16 68,954,860 68,968,248 RGD:6480464
G Ephx1 epoxide hydrolase 1 JBrowse link 13 99,271,390 99,300,580 RGD:6480464
G Fam162a family with sequence similarity 162, member A JBrowse link 11 67,618,683 67,646,253 RGD:6480464
G Fcgr2a Fc fragment of IgG receptor IIa JBrowse link 13 91,146,878 91,163,691 RGD:6480464
G Fkbp4 FKBP prolyl isomerase 4 JBrowse link 4 161,748,993 161,757,447 RGD:6480464
G Fn1 fibronectin 1 JBrowse link 9 78,900,111 78,969,018 RGD:6480464
G Gadd45a growth arrest and DNA-damage-inducible, alpha JBrowse link 4 97,782,512 97,784,814 RGD:6480464
G Gas6 growth arrest specific 6 JBrowse link 16 81,213,364 81,243,824 RGD:6480464
G Gclc glutamate-cysteine ligase, catalytic subunit JBrowse link 8 85,059,051 85,097,471 RGD:6480464
G Gdf15 growth differentiation factor 15 JBrowse link 16 20,555,395 20,557,978 RGD:6480464
G Gls2 glutaminase 2 JBrowse link 7 2,605,679 2,621,853 RGD:6480464
G Gnmt glycine N-methyltransferase JBrowse link 9 16,565,274 16,568,626 RGD:6480464
G Gpr108 G protein-coupled receptor 108 JBrowse link 9 9,704,300 9,714,767 RGD:6480464
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 JBrowse link X 127,561,843 127,829,763 RGD:6480464
G Grpel1 GrpE-like 1, mitochondrial JBrowse link 14 79,458,951 79,464,782 RGD:6480464
G Gsr glutathione-disulfide reductase JBrowse link 16 62,197,617 62,239,987 RGD:6480464
G Gss glutathione synthetase JBrowse link 3 151,076,254 151,106,557 RGD:6480464
G Gsta2 glutathione S-transferase alpha 2 JBrowse link 8 85,640,081 85,645,621 RGD:6480464
G Gsta5 glutathione S-transferase alpha 5 JBrowse link 8 85,553,659 85,564,914 RGD:6480464
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464
G Hdc histidine decarboxylase JBrowse link 3 119,057,524 119,075,599 RGD:6480464
G Hectd1 HECT domain E3 ubiquitin protein ligase 1 JBrowse link 6 72,509,658 72,596,285 RGD:6480464
G Hmgb2 high mobility group box 2 JBrowse link 16 36,077,615 36,080,191 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Hsf1 heat shock transcription factor 1 JBrowse link 7 117,538,523 117,565,478 RGD:6480464
G Hspa9 heat shock protein family A (Hsp70) member 9 JBrowse link 18 27,731,072 27,749,235 RGD:6480464
G Hspb1 heat shock protein family B (small) member 1 JBrowse link 12 23,839,390 23,841,051 RGD:6480464
G Hspe1 heat shock protein family E (Hsp10) member 1 JBrowse link 9 61,691,246 61,724,948 RGD:6480464
G Hsph1 heat shock protein family H (Hsp110) member 1 JBrowse link 12 6,322,685 6,341,898 RGD:6480464
G Ide insulin degrading enzyme JBrowse link 1 255,914,465 256,014,168 RGD:6480464
G Igfbp1 insulin-like growth factor binding protein 1 JBrowse link 14 87,448,716 87,453,783 RGD:6480464
G Igfbp3 insulin-like growth factor binding protein 3 JBrowse link 14 87,457,647 87,465,374 RGD:6480464
G Irf1 interferon regulatory factor 1 JBrowse link 10 39,109,530 39,116,532 RGD:6480464
G Lama5 laminin subunit alpha 5 JBrowse link 3 175,553,042 175,601,112 RGD:6480464
G Lgals3 galectin 3 JBrowse link 15 24,153,602 24,165,537 RGD:6480464
G Map2k6 mitogen-activated protein kinase kinase 6 JBrowse link 10 98,707,160 98,823,054 RGD:6480464
G Mat1a methionine adenosyltransferase 1A JBrowse link 16 18,690,649 18,709,135 RGD:6480464
G Mcm6 minichromosome maintenance complex component 6 JBrowse link 13 45,042,882 45,068,073 RGD:6480464
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:6480464
G Mgmt O-6-methylguanine-DNA methyltransferase JBrowse link 1 209,237,255 209,464,189 RGD:6480464
G Mt1 metallothionein 1 JBrowse link 19 11,301,991 11,303,007 RGD:6480464
G Mt2A metallothionein 2A JBrowse link 19 11,307,966 11,308,740 RGD:6480464
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:6480464
G Naglt1 Na+ dependent glucose transporter 1 JBrowse link 20 45,095,232 45,107,532 RGD:6480464
G Nap1l1 nucleosome assembly protein 1-like 1 JBrowse link 7 54,213,305 54,237,880 RGD:6480464
G Nhej1 nonhomologous end-joining factor 1 JBrowse link 9 82,230,230 82,327,923 RGD:6480464
G Npm1 nucleophosmin 1 JBrowse link 10 18,080,949 18,091,062 RGD:6480464
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:6480464
G Nrg1 neuregulin 1 JBrowse link 16 62,969,573 64,065,063 RGD:6480464
G Nupr1 nuclear protein 1, transcriptional regulator JBrowse link 1 194,767,484 194,769,519 RGD:6480464
G Oat ornithine aminotransferase JBrowse link 1 204,562,289 204,582,070 RGD:6480464
G Obp3 alpha-2u globulin PGCL4 JBrowse link 5 77,313,357 77,316,875 RGD:6480464
G Odc1 ornithine decarboxylase 1 JBrowse link 6 42,852,529 42,859,142 RGD:6480464
G Pcna proliferating cell nuclear antigen JBrowse link 3 124,880,698 124,884,570 RGD:6480464
G Pdcd4 programmed cell death 4 JBrowse link 1 274,616,625 274,648,204 RGD:6480464
G Phgdh phosphoglycerate dehydrogenase JBrowse link 2 200,484,245 200,513,564 RGD:6480464
G Phlda3 pleckstrin homology-like domain, family A, member 3 JBrowse link 13 52,588,917 52,592,002 RGD:6480464
G Pmm1 phosphomannomutase 1 JBrowse link 7 123,183,504 123,193,874 RGD:6480464
G Psma1 proteasome 20S subunit alpha 1 JBrowse link 1 183,733,567 183,744,586 RGD:6480464
G Psma2 proteasome 20S subunit alpha 2 JBrowse link 17 53,091,937 53,102,324 RGD:6480464
G Psma4 proteasome 20S subunit alpha 4 JBrowse link 8 59,532,456 59,539,916 RGD:6480464
G Psma5 proteasome 20S subunit alpha 5 JBrowse link 2 211,050,344 211,073,706 RGD:6480464
G Psma7 proteasome 20S subunit alpha 7 JBrowse link 3 175,420,042 175,426,384 RGD:6480464
G Psmb1 proteasome 20S subunit beta 1 JBrowse link 1 57,470,878 57,491,359 RGD:6480464
G Psmb3 proteasome 20S subunit beta 3 JBrowse link 10 85,646,646 85,653,729 RGD:6480464
G Psmb4 proteasome 20S subunit beta 4 JBrowse link 2 196,043,546 196,046,320 RGD:6480464
G Psmb5 proteasome 20S subunit beta 5 JBrowse link 15 33,259,039 33,263,634 RGD:6480464
G Psmb8 proteasome 20S subunit beta 8 JBrowse link 20 3,990,809 3,993,772 RGD:6480464
G Psmb9 proteasome 20S subunit beta 9 JBrowse link 20 3,973,424 3,978,845 RGD:6480464
G Psmc1 proteasome 26S subunit, ATPase 1 JBrowse link 6 124,123,283 124,135,644 RGD:6480464
G Psmc2 proteasome 26S subunit, ATPase 2 JBrowse link 4 9,867,132 9,881,383 RGD:6480464
G Psmc4 proteasome 26S subunit, ATPase 4 JBrowse link 1 84,978,220 84,986,536 RGD:6480464
G Psmc5 proteasome 26S subunit, ATPase 5 JBrowse link 10 94,445,877 94,451,811 RGD:6480464
G Psmd1 proteasome 26S subunit, non-ATPase 1 JBrowse link 9 93,080,618 93,155,033 RGD:6480464
G Ptp4a1 protein tyrosine phosphatase 4A1 JBrowse link 9 37,223,363 37,254,222 RGD:6480464
G Pttg1 PTTG1 regulator of sister chromatid separation, securin JBrowse link 10 29,014,332 29,026,088 RGD:6480464
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:6480464
G Rheb Ras homolog, mTORC1 binding JBrowse link 4 6,827,429 6,873,384 RGD:6480464
G Rhob ras homolog family member B JBrowse link 6 33,689,127 33,691,301 RGD:6480464
G Rpl10 ribosomal protein L10 JBrowse link X 156,438,251 156,440,461 RGD:6480464
G Rpl10a ribosomal protein L10A JBrowse link 20 7,908,309 7,910,867 RGD:6480464
G Rpl13 ribosomal protein L13 JBrowse link 19 55,917,489 55,920,040 RGD:6480464
G Rpl15 ribosomal protein L15 JBrowse link 15 8,188,717 8,192,153 RGD:6480464
G Rpl17 ribosomal protein L17 JBrowse link 18 70,969,733 70,972,839 RGD:6480464
G Rpl23 ribosomal protein L23 JBrowse link 10 85,721,398 85,725,359 RGD:6480464
G Rpl6 ribosomal protein L6 JBrowse link 12 40,877,578 40,882,032 RGD:6480464
G Rpl7a ribosomal protein L7a JBrowse link 3 5,458,985 5,461,627 RGD:6480464
G Rpl8 ribosomal protein L8 JBrowse link 7 117,967,608 117,969,886 RGD:6480464
G Rps15a ribosomal protein S15a JBrowse link 1 187,759,865 187,766,734 RGD:6480464
G Rps19 ribosomal protein S19 JBrowse link 1 81,750,873 81,756,629 RGD:6480464
G Rps24 ribosomal protein S24 JBrowse link 16 757,390 762,091 RGD:6480464
G Rps27l ribosomal protein S27-like JBrowse link 8 72,741,155 72,746,090 RGD:6480464
G Rps3 ribosomal protein S3 JBrowse link 1 164,435,868 164,441,167 RGD:6480464
G Rps4x ribosomal protein S4, X-linked JBrowse link X 72,074,108 72,078,551 RGD:6480464
G Rps7 ribosomal protein S7 JBrowse link 6 47,899,525 47,904,389 RGD:6480464
G Rpsa ribosomal protein SA JBrowse link 8 128,806,053 128,809,987 RGD:6480464
G Rsad2 radical S-adenosyl methionine domain containing 2 JBrowse link 6 45,655,947 45,669,083 RGD:6480464
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:6480464
G RT1-Da RT1 class II, locus Da JBrowse link 20 4,127,644 4,132,616 RGD:6480464
G RT1-EC2 RT1 class Ib, locus EC2 RGD:6480464
G Sds serine dehydratase JBrowse link 12 41,620,429 41,627,741 RGD:6480464
G Selenow selenoprotein W JBrowse link 1 77,530,692 77,535,765 RGD:6480464
G Serpina7 serpin family A member 7 JBrowse link X 110,226,565 110,232,202 RGD:6480464
G Sptan1 spectrin, alpha, non-erythrocytic 1 JBrowse link 3 8,534,437 8,599,259 RGD:6480464
G Stat1 signal transducer and activator of transcription 1 JBrowse link 9 54,287,540 54,327,958 RGD:6480464
G Stmn1 stathmin 1 JBrowse link 5 152,680,412 152,686,807 RGD:6480464
G Tap1 transporter 1, ATP binding cassette subfamily B member JBrowse link 20 3,979,302 3,989,669 RGD:6480464
G Tat tyrosine aminotransferase JBrowse link 19 41,675,639 41,686,195 RGD:6480464
G Timm10b translocase of inner mitochondrial membrane 10B JBrowse link 1 170,471,265 170,474,111 RGD:6480464
G Timp1 TIMP metallopeptidase inhibitor 1 JBrowse link X 1,364,771 1,369,451 RGD:6480464
G Tmsb10 thymosin, beta 10 JBrowse link 4 100,882,216 100,883,303 RGD:6480464
G Tnfaip3 TNF alpha induced protein 3 JBrowse link 1 14,401,103 14,416,369 RGD:6480464
G Top2a DNA topoisomerase II alpha JBrowse link 10 86,901,467 86,930,947 RGD:6480464
G Tpd52 tumor protein D52 JBrowse link 2 94,959,732 95,041,277 RGD:6480464
G Trappc10 trafficking protein particle complex 10 JBrowse link 20 11,168,298 11,228,634 RGD:6480464
G Tsc22d1 TSC22 domain family, member 1 JBrowse link 15 58,554,358 58,658,156 RGD:6480464
G Tuba1c tubulin, alpha 1C JBrowse link 7 140,716,113 140,723,717 RGD:6480464
G Tubb5 tubulin, beta 5 class I JBrowse link 20 3,422,448 3,426,420 RGD:6480464
G Tyms thymidylate synthetase JBrowse link 9 121,918,875 121,931,564 RGD:6480464
G Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C JBrowse link 9 95,233,957 95,302,822 RGD:6480464
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 JBrowse link 14 22,724,399 22,736,148 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:6480464
G Vim vimentin JBrowse link 17 80,882,715 80,891,200 RGD:6480464
G Xdh xanthine dehydrogenase JBrowse link 6 25,149,570 25,211,273 RGD:6480464
G Zmat3 zinc finger, matrin type 3 JBrowse link 2 118,715,229 118,746,109 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19662
    role 19606
      biological role 19604
        aetiopathogenetic role 18761
          carcinogenic agent 17766
            2-nitrofluorene 179
Path 2
Term Annotations click to browse term
  CHEBI ontology 19662
    subatomic particle 19658
      composite particle 19658
        hadron 19658
          baryon 19658
            nucleon 19658
              atomic nucleus 19658
                atom 19658
                  main group element atom 19539
                    main group molecular entity 19539
                      s-block molecular entity 19322
                        hydrogen molecular entity 19312
                          hydrides 18241
                            organic hydride 17532
                              organic fundamental parent 17532
                                hydrocarbon 16937
                                  cyclic hydrocarbon 15098
                                    arene 15085
                                      polycyclic arene 14515
                                        ortho-fused polycyclic arene 9538
                                          fluorene 551
                                            2-nitrofluorene 179
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.