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ONTOLOGY REPORT - ANNOTATIONS


Term:20-hydroxycholesterol
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Accession:CHEBI:1296 term browser browse the term
Definition:An oxysterol that is cholesterol substituted by a hydroxy group at position 20.
Synonyms:exact_synonym: cholest-5-ene-3beta,20-diol
 related_synonym: (20S)-20-Hydroxycholesterol;   (3beta)-cholest-5-ene-3,20-diol;   20(S)-OHC;   20(S)-hydroxycholesterol;   20alpha-Hydroxycholesterol;   Formula=C27H46O2;   InChI=1S/C27H46O2/c1-18(2)7-6-14-27(5,29)24-11-10-22-21-9-8-19-17-20(28)12-15-25(19,3)23(21)13-16-26(22,24)4/h8,18,20-24,28-29H,6-7,9-17H2,1-5H3/t20-,21-,22-,23-,24-,25-,26-,27-/m0/s1;   InChIKey=MCKLJFJEQRYRQT-APGJSSKUSA-N;   SMILES=C1[C@@]2([C@]3(CC[C@]4([C@]([C@@]3(CC=C2C[C@H](C1)O)[H])(CC[C@@]4([C@](C)(CCCC(C)C)O)[H])[H])C)[H])C
 alt_id: CHEBI:43170
 xref: CAS:516-72-3 "ChemIDplus";   CAS:516-72-3 "KEGG COMPOUND";   DrugBank:DB04704;   HMDB:HMDB0006283;   KEGG:C05500;   LIPID_MAPS_instance:LMST01010201 "LIPID MAPS"
 xref_mesh: MESH:C025813
 xref: MetaCyc:2-HYDROXY-CHOLESTEROL;   PDBeChem:HC2;   PMID:1270422 "Europe PMC";   PMID:17200122 "Europe PMC";   PMID:17638575 "Europe PMC";   PMID:19839776 "Europe PMC";   PMID:20683129 "Europe PMC";   PMID:22231273 "Europe PMC";   PMID:23831757 "Europe PMC";   PMID:24596093 "Europe PMC";   PMID:25523141 "Europe PMC";   PMID:25765115 "Europe PMC";   PMID:26902390 "Europe PMC";   PMID:6042125 "Europe PMC";   Reaxys:2062337 "Reaxys"


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20-hydroxycholesterol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 JBrowse link 8 62,798,317 62,809,848 RGD:6480464
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 JBrowse link 5 19,358,734 19,368,431 RGD:6480464
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 JBrowse link X 21,696,796 21,699,241 RGD:6480464
G Mc2r melanocortin 2 receptor JBrowse link 18 64,166,959 64,178,729 RGD:6480464
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 JBrowse link 3 22,998,900 23,020,441 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19614
    chemical entity 19612
      molecular entity 19609
        polyatomic entity 19526
          heteroatomic molecular entity 19444
            hydroxides 18944
              organic hydroxy compound 18464
                hydroxy steroid 12101
                  20-hydroxy steroid 45
                    20-hydroxycholesterol 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19614
    subatomic particle 19610
      composite particle 19610
        hadron 19610
          baryon 19610
            nucleon 19610
              atomic nucleus 19610
                atom 19610
                  main group element atom 19489
                    p-block element atom 19489
                      carbon group element atom 19362
                        carbon atom 19354
                          organic molecular entity 19354
                            organic molecule 19272
                              organic cyclic compound 19061
                                organic polycyclic compound 15984
                                  steroid 12549
                                    hydroxy steroid 12101
                                      3-hydroxy steroid 9987
                                        3beta-hydroxy steroid 1969
                                          3beta-hydroxy-Delta(5)-steroid 1832
                                            cholesterol 304
                                              oxysterol 88
                                                20-hydroxycholesterol 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.