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Term:3,3',5,5'-tetraiodothyroacetic acid
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Accession:CHEBI:131194 term browser browse the term
Definition:A monocarboxylic acid that is thyroacetic acid carrying four iodo substituents at positions 3, 3', 5 and 5'.
Synonyms:related_synonym: 3,5-Diiodo-4-(4-hydroxy-3,5-diiodophenoxy)benzeneacetic acid;   Acide 3,5,3',5'-tetraiodothyroacetique;   Formula=C14H8I4O4;   InChI=1S/C14H8I4O4/c15-8-4-7(5-9(16)13(8)21)22-14-10(17)1-6(2-11(14)18)3-12(19)20/h1-2,4-5,21H,3H2,(H,19,20);   InChIKey=PPJYSSNKSXAVDB-UHFFFAOYSA-N;   SMILES=O(C1=CC(=C(C(=C1)I)O)I)C=2C(=CC(=CC2I)CC(O)=O)I;   Tetrac;   Tetraiodothyroacetic acid
 alt_id: CHEBI:45954
 xref: CAS:67-30-1 "ChemIDplus";   DrugBank:DB01751;   LINCS:LSM-25628
 xref_mesh: MESH:C011126
 xref: MetaCyc:CPD-11403;   PDBeChem:T4A;   PMID:23103412 "Europe PMC";   PMID:24214887 "Europe PMC";   PMID:25258542 "Europe PMC";   PMID:25628605 "Europe PMC";   PMID:25866761 "Europe PMC";   PMID:26041883 "Europe PMC";   PMID:26307023 "Europe PMC";   PMID:26384643 "Europe PMC";   PMID:26756636 "Europe PMC";   Reaxys:2173215 "Reaxys"

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3,3',5,5'-tetraiodothyroacetic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Ncor1 nuclear receptor co-repressor 1 JBrowse link 10 48,629,121 48,772,890 RGD:6480464
G Ncor2 nuclear receptor co-repressor 2 JBrowse link 12 36,871,917 37,033,701 RGD:6480464
G Thrb thyroid hormone receptor beta JBrowse link 15 8,890,578 9,239,815 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19741
    role 19688
      biological role 19686
        biochemical role 19190
          apoptosis inducer 10831
            3,3',5,5'-tetraiodothyroacetic acid 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    p-block element atom 19622
                      carbon group element atom 19515
                        carbon atom 19508
                          organic molecular entity 19508
                            organic group 18423
                              organic divalent group 18414
                                organodiyl group 18414
                                  carbonyl group 18301
                                    carbonyl compound 18301
                                      carboxylic acid 17966
                                        monocarboxylic acid 17265
                                          3,3',5,5'-tetraiodothyroacetic acid 6
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.