Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:N,N-bis(2-hydroxypropyl)nitrosamine
go back to main search page
Accession:CHEBI:131518 term browser browse the term
Definition:A nitrosamine that is dipropylamine in which the hydrogen attached to the nitrogen has been replaced by a nitroso group. It is a genotoxic carcinogen, targeting the lung, liver, thyroid, and kidney.
Synonyms:exact_synonym: N,N-bis(2-hydroxypropyl)nitrous amide
 related_synonym: 2,2'-bishydroxypropylnitrosamine;   2,2'-dihydroxy-di-n-propylnitrosoamine;   DHPN;   Formula=C6H14N2O3;   InChI=1S/C6H14N2O3/c1-5(9)3-8(7-11)4-6(2)10/h5-6,9-10H,3-4H2,1-2H3;   InChIKey=MNIGYIKCFSPQRJ-UHFFFAOYSA-N;   N,N-di-(2-hydroxypropyl)nitrosamine;   N-bis(2-hydroxypropyl)nitrosamine;   N-nitroso-N,N-di(2-hydroxypropyl)amine;   N-nitrosobis(2-hydroxypropyl)amine;   N-nitrosodiisopropanolamine;   SMILES=CC(CN(CC(C)O)N=O)O;   di(2-hydroxypropyl)nitrosamine;   diisopropanolnitrosamine
 xref: CAS:53609-64-6 "ChemIDplus"
 xref_mesh: MESH:C012457
 xref: PMID:15201437 "Europe PMC";   PMID:15223773 "Europe PMC";   PMID:22634710 "Europe PMC";   PMID:24377951 "Europe PMC";   PMID:25024166 "Europe PMC";   PMID:6533030 "Europe PMC";   PMID:6533034 "Europe PMC";   PMID:728889 "Europe PMC";   Reaxys:2245909 "Reaxys"


show annotations for term's descendants       view all columns           Sort by:
 
N,N-bis(2-hydroxypropyl)nitrosamine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cp ceruloplasmin JBrowse link 2 104,744,249 104,803,034 RGD:6480464
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:6480464
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:6480464
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:6480464
G Kras KRAS proto-oncogene, GTPase JBrowse link 4 179,482,562 179,515,483 RGD:6480464
G Mki67 marker of proliferation Ki-67 JBrowse link 1 207,993,895 208,020,454 RGD:6480464
G Pcna proliferating cell nuclear antigen JBrowse link 3 124,880,698 124,884,570 RGD:6480464
G Tshb thyroid stimulating hormone subunit beta JBrowse link 2 205,207,799 205,215,199 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19662
    role 19606
      biological role 19604
        aetiopathogenetic role 18761
          carcinogenic agent 17766
            N,N-bis(2-hydroxypropyl)nitrosamine 8
              N-nitrobis(2-hydroxypropyl)amine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19662
    subatomic particle 19658
      composite particle 19658
        hadron 19658
          baryon 19658
            nucleon 19658
              atomic nucleus 19658
                atom 19658
                  main group element atom 19539
                    p-block element atom 19539
                      chalcogen 19228
                        oxygen atom 19182
                          oxygen molecular entity 19182
                            hydroxides 18964
                              organic hydroxy compound 18510
                                polyol 7615
                                  diol 2696
                                    N,N-bis(2-hydroxypropyl)nitrosamine 8
                                      N-nitrobis(2-hydroxypropyl)amine 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.