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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:EC 2.7.11.17 (Ca(2+)/calmodulin-dependent protein kinase) inhibitor
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Accession:CHEBI:131794 term browser browse the term
Definition:Any EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of a Ca(2+)/calmodulin-dependent protein kinase (EC 2.7.11.17).
Synonyms:related_synonym: ATP:caldesmon O-phosphotransferase inhibitor;   ATP:caldesmon O-phosphotransferase inhibitors;   ATP:protein phosphotransferase ((2+)/calmodulin-dependent) inhibitor;   ATP:protein phosphotransferase ((2+)/calmodulin-dependent) inhibitors;   CAM PKII inhibitor;   CAM PKII inhibitors;   Ca(2+)/calmodulin-dependent microtubule-associated protein 2 kinase inhibitor;   Ca(2+)/calmodulin-dependent microtubule-associated protein 2 kinase inhibitors;   Ca(2+)/calmodulin-dependent protein kinase (EC 2.7.11.17) inhibitors;   Ca(2+)/calmodulin-dependent protein kinase 1 inhibitor;   Ca(2+)/calmodulin-dependent protein kinase 1 inhibitors;   Ca(2+)/calmodulin-dependent protein kinase II inhibitor;   Ca(2+)/calmodulin-dependent protein kinase II inhibitors;   Ca(2+)/calmodulin-dependent protein kinase IV inhibitor;   Ca(2+)/calmodulin-dependent protein kinase IV inhibitors;   Ca(2+)/calmodulin-dependent protein kinase inhibitor;   Ca(2+)/calmodulin-dependent protein kinase inhibitors;   Ca(2+)/calmodulin-dependent protein kinase kinase beta inhibitor;   Ca(2+)/calmodulin-dependent protein kinase kinase beta inhibitors;   Ca(2+)/calmodulin-dependent protein kinase kinase inhibitor;   Ca(2+)/calmodulin-dependent protein kinase kinase inhibitors;   CaM kinase II inhibitor;   CaM kinase II inhibitors;   CaM kinase inhibitor;   CaM kinase inhibitors;   CaM-regulated serine/threonine kinase inhibitor;   CaM-regulated serine/threonine kinase inhibitors;   CaMKI inhibitor;   CaMKI inhibitors;   CaMKII inhibitor;   CaMKII inhibitors;   CaMKIV inhibitor;   CaMKIV inhibitors;   CaMKKalpha inhibitor;   CaMKKalpha inhibitors;   CaMKKbeta inhibitor;   CaMKKbeta inhibitors;   EC 2.7.11.17 inhibitor;   EC 2.7.11.17 inhibitors;   STK20 inhibitor;   STK20 inhibitors;   caldesmon kinase (phosphorylating) inhibitor;   caldesmon kinase (phosphorylating) inhibitors;   caldesmon kinase inhibitor;   caldesmon kinase inhibitors;   calmodulin-dependent kinase II inhibitor;   calmodulin-dependent kinase II inhibitors;   microtubule-associated protein 2 kinase inhibitor;   microtubule-associated protein 2 kinase inhibitors
 xref: Wikipedia:CAMK


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KN-93 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A multiple interactions ISO KN 93 inhibits the reaction [Digoxin results in increased expression of ABCB1 protein]; KN 93 inhibits the reaction [Ouabain results in increased expression of ABCB1 protein] CTD PMID:19647009 NCBI chr 5:8,567,091...8,748,575
Ensembl chr 5:8,660,077...8,748,575
JBrowse link
G Aco1 aconitase 1 multiple interactions ISO KN 93 inhibits the reaction [Cadmium Chloride affects the localization of ACO1 protein] CTD PMID:25106854 NCBI chr 4:40,143,265...40,199,009
Ensembl chr 4:40,143,081...40,198,338
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant multiple interactions EXP KN 93 affects the reaction [[Cadmium co-treated with TNFSF11 protein co-treated with CSF1R protein] affects the expression of ACP5 protein] CTD PMID:32522522 NCBI chr 9:22,126,727...22,135,746
Ensembl chr 9:22,126,727...22,135,711
JBrowse link
G Ahr aryl-hydrocarbon receptor multiple interactions ISO KN 93 inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of AHR protein] CTD PMID:18089838 NCBI chr12:35,497,979...35,534,989
Ensembl chr12:35,497,974...35,535,038
JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor multiple interactions ISO KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHRR mRNA] CTD PMID:18089838 NCBI chr13:74,211,118...74,292,331
Ensembl chr13:74,211,118...74,292,331
JBrowse link
G Aifm1 apoptosis-inducing factor, mitochondrion-associated 1 multiple interactions EXP KN 93 inhibits the reaction [Cadmium Chloride affects the localization of AIFM1 protein] CTD PMID:18506790 NCBI chr  X:48,474,944...48,513,563
Ensembl chr  X:48,474,944...48,513,563
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 multiple interactions ISO KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein]
KN 93 inhibits the reaction [rutacarpine results in increased phosphorylation of AKT1 protein]
CTD PMID:19233221, PMID:21933187, PMID:28025122 NCBI chr12:112,653,821...112,674,884
Ensembl chr12:112,653,821...112,674,884
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions ISO KN 93 inhibits the reaction [cadmium acetate results in increased expression of ATF4 protein] CTD PMID:29883672 NCBI chr15:80,255,184...80,257,545
Ensembl chr15:80,255,184...80,257,541
JBrowse link
G Calcr calcitonin receptor multiple interactions EXP KN 93 inhibits the reaction [TNFSF11 protein results in increased expression of CALCR mRNA] CTD PMID:21869564 NCBI chr 6:3,685,678...3,764,713
Ensembl chr 6:3,685,680...3,764,714
JBrowse link
G Camk1 calcium/calmodulin-dependent protein kinase I decreases activity ISO KN 93 results in decreased activity of CAMK1 protein CTD PMID:12193581 NCBI chr 6:113,334,124...113,343,922
Ensembl chr 6:113,334,124...113,343,984
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions EXP
ISO
[KN 93 co-treated with Losartan] inhibits the reaction [bisphenol A results in increased phosphorylation of CAMK2A protein]; KN 93 inhibits the reaction [bisphenol A results in increased phosphorylation of CAMK2A protein]
KN 93 inhibits the reaction [rutacarpine results in increased phosphorylation of CAMK2A protein]
KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of CAMK2A protein]; KN 93 inhibits the reaction [Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]]; KN 93 inhibits the reaction [Excitatory Amino Acid Agents promotes the reaction [CAMK2A protein binds to DRD3 protein]]; KN 93 inhibits the reaction [Ionomycin promotes the reaction [CAMK2A protein binds to DRD3 protein]]; KN 93 inhibits the reaction [Ionomycin promotes the reaction [CAMK2A protein modified form binds to DRD3 protein]]
CTD PMID:19217379, PMID:21933187, PMID:25103225, PMID:28025122 NCBI chr18:60,925,307...60,988,152
Ensembl chr18:60,925,618...60,988,152
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II, delta multiple interactions ISO KN 93 inhibits the reaction [Cadmium affects the localization of CAMK2D protein] CTD PMID:22553113 NCBI chr 3:126,595,487...126,846,326
Ensembl chr 3:126,596,302...126,846,326
JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV multiple interactions ISO KN 93 inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of CAMK4 protein] CTD PMID:17973980 NCBI chr18:32,934,941...33,195,767
Ensembl chr18:32,934,931...33,191,228
JBrowse link
G Casp12 caspase 12 multiple interactions ISO KN 93 inhibits the reaction [cadmium acetate results in increased cleavage of CASP12 protein] CTD PMID:29883672 NCBI chr 9:5,345,442...5,373,034
Ensembl chr 9:5,345,430...5,373,032
JBrowse link
G Casp3 caspase 3 multiple interactions ISO
EXP
KN 93 inhibits the reaction [cadmium acetate results in increased cleavage of CASP3 protein]; KN 93 inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; KN 93 promotes the reaction [Cadmium Chloride results in increased cleavage of CASP3 protein]
KN 93 inhibits the reaction [rutecarpine inhibits the reaction [tert-Butylhydroperoxide results in increased activity of CASP3 protein]]
KN 93 inhibits the reaction [bisphenol A results in increased expression of and results in increased cleavage of CASP3 protein]; KN 93 inhibits the reaction [GW 7845 results in increased activity of CASP3 protein]
CTD PMID:19233221, PMID:20810541, PMID:26096086, PMID:26923100, PMID:28025122, PMID:29883672 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Ccl1 chemokine (C-C motif) ligand 1 multiple interactions ISO KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CCL1 mRNA] CTD PMID:18089838 NCBI chr11:82,176,666...82,179,812
Ensembl chr11:82,176,657...82,305,690
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO KN 93 results in decreased expression of CCND1 protein CTD PMID:15958590 NCBI chr 7:144,929,931...144,939,831
Ensembl chr 7:144,929,931...144,939,925
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO KN 93 inhibits the reaction [Capsaicin results in increased phosphorylation of CREB1 protein]; KN 93 inhibits the reaction [Nicotine results in increased phosphorylation of CREB1 protein] CTD PMID:15385614, PMID:15631885, PMID:21113126 NCBI chr 1:64,532,794...64,604,548
Ensembl chr 1:64,532,645...64,604,548
JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions EXP KN 93 affects the reaction [[Cadmium co-treated with TNFSF11 protein co-treated with CSF1R protein] affects the expression of ACP5 protein]; KN 93 affects the reaction [[Cadmium co-treated with TNFSF11 protein co-treated with CSF1R protein] affects the expression of NFATC1 protein] CTD PMID:32522522 NCBI chr18:61,105,572...61,131,139
Ensembl chr18:61,100,598...61,132,149
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 multiple interactions ISO KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CXCL8 mRNA] CTD PMID:18089838 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067
JBrowse link
G Cycs cytochrome c, somatic multiple interactions EXP KN 93 inhibits the reaction [GW 7845 affects the localization of CYCS protein] CTD PMID:20810541 NCBI chr 6:50,562,563...50,566,569
Ensembl chr 6:50,562,563...50,566,538
JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 multiple interactions ISO KN 93 inhibits the reaction [Potassium results in increased expression of CYP11B2 mRNA] CTD PMID:12193581 NCBI chr15:74,850,618...74,856,231
Ensembl chr15:74,851,010...74,856,318
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO KN 93 inhibits the reaction [STO 609 results in increased activity of CYP1A1 protein]; KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein] CTD PMID:18089838, PMID:18755850, PMID:23298284 NCBI chr 9:57,687,928...57,703,824
Ensembl chr 9:57,687,928...57,703,824
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] CTD PMID:18089838 NCBI chr17:79,706,940...79,715,061
Ensembl chr17:79,701,537...79,715,061
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO KN 93 inhibits the reaction [cadmium acetate results in increased expression of DDIT3 protein] CTD PMID:29883672 NCBI chr10:127,290,793...127,296,291
Ensembl chr10:127,290,774...127,296,288
Ensembl chr10:127,290,774...127,296,288
JBrowse link
G Drd3 dopamine receptor D3 multiple interactions ISO KN 93 inhibits the reaction [Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]]; KN 93 inhibits the reaction [Excitatory Amino Acid Agents promotes the reaction [CAMK2A protein binds to DRD3 protein]]; KN 93 inhibits the reaction [Ionomycin promotes the reaction [CAMK2A protein binds to DRD3 protein]]; KN 93 inhibits the reaction [Ionomycin promotes the reaction [CAMK2A protein modified form binds to DRD3 protein]]; KN 93 inhibits the reaction [Ionomycin results in increased phosphorylation of DRD3 protein] CTD PMID:19217379 NCBI chr16:43,754,015...43,825,982
Ensembl chr16:43,754,026...43,822,932
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EGFR protein] CTD PMID:19233221 NCBI chr11:16,752,203...16,913,907
Ensembl chr11:16,752,203...16,918,158
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EIF4EBP1 protein] CTD PMID:21933187 NCBI chr 8:27,260,327...27,275,656
Ensembl chr 8:27,260,329...27,276,674
JBrowse link
G Foxo3 forkhead box O3 multiple interactions ISO KN 93 inhibits the reaction [Cadmium Chloride results in decreased activity of FOXO3 protein]; KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of FOXO3 protein] CTD PMID:23673518 NCBI chr10:42,181,845...42,276,695
Ensembl chr10:42,181,841...42,276,755
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions ISO KN 93 inhibits the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein] CTD PMID:21879721 NCBI chr11:102,887,336...102,897,200
Ensembl chr11:102,887,336...102,900,912
JBrowse link
G Gria1 glutamate receptor, ionotropic, AMPA1 (alpha 1) multiple interactions ISO KN 93 inhibits the reaction [Capsaicin results in increased phosphorylation of GRIA1 protein] CTD PMID:12019337 NCBI chr11:57,011,571...57,330,244
Ensembl chr11:57,011,387...57,330,244
JBrowse link
G Hdac5 histone deacetylase 5 multiple interactions EXP KN 93 inhibits the reaction [Potassium Chloride results in increased phosphorylation of HDAC5 protein] CTD PMID:17988634 NCBI chr11:102,195,747...102,230,172
Ensembl chr11:102,194,432...102,230,166
JBrowse link
G Hexb hexosaminidase B multiple interactions ISO KN 93 inhibits the reaction [Ionomycin results in increased secretion of HEXB protein] CTD PMID:14499669 NCBI chr13:97,176,331...97,198,357
Ensembl chr13:97,176,331...97,198,357
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit multiple interactions ISO KN 93 inhibits the reaction [Digoxin affects the localization of HIF1A protein]; KN 93 inhibits the reaction [Digoxin results in increased phosphorylation of HIF1A protein]; KN 93 inhibits the reaction [Ouabain affects the localization of HIF1A protein]; KN 93 inhibits the reaction [Ouabain results in increased phosphorylation of HIF1A protein] CTD PMID:19647009 NCBI chr12:73,901,324...73,947,554
Ensembl chr12:73,901,375...73,947,530
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO KN 93 inhibits the reaction [rutacarpine results in increased expression of HMOX1 mRNA]; KN 93 inhibits the reaction [rutacarpine results in increased expression of HMOX1 protein] CTD PMID:28025122 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G Hspa5 heat shock protein 5 multiple interactions ISO KN 93 inhibits the reaction [cadmium acetate results in increased expression of HSPA5 protein] CTD PMID:29883672 NCBI chr 2:34,772,090...34,776,529
Ensembl chr 2:34,771,970...34,777,547
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of IL1B mRNA] CTD PMID:18089838 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Itgb7 integrin beta 7 multiple interactions ISO KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of ITGB7 mRNA] CTD PMID:18089838 NCBI chr15:102,215,994...102,233,405
Ensembl chr15:102,215,995...102,231,944
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 multiple interactions ISO KN 93 inhibits the reaction [Phenylephrine results in increased activity of MAP3K5 protein] CTD PMID:15629441 NCBI chr10:19,934,101...20,142,750
Ensembl chr10:19,934,472...20,142,753
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions ISO
EXP
KN 93 inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK1 protein]; KN 93 promotes the reaction [wortmannin inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK1 protein]]; wortmannin promotes the reaction [KN 93 inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK1 protein]]
KN 93 affects the reaction [Ptychodiscus brevis T2 toxin affects the phosphorylation of MAPK1 protein]
KN 93 inhibits the reaction [cadmium acetate results in increased phosphorylation of MAPK1 protein]; KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK1 protein]; KN 93 inhibits the reaction [diphenylditelluride results in increased phosphorylation of MAPK1 protein]; KN 93 inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased phosphorylation of MAPK1 protein]
CTD PMID:15086530, PMID:15355987, PMID:19233221, PMID:21879721, PMID:21933187, PMID:28181390, PMID:29883672 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453
JBrowse link
G Mapk14 mitogen-activated protein kinase 14 multiple interactions ISO KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK14 protein] CTD PMID:21933187 NCBI chr17:28,691,342...28,748,405
Ensembl chr17:28,691,329...28,748,406
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions ISO
EXP
KN 93 inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK3 protein]; KN 93 promotes the reaction [wortmannin inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK3 protein]]; wortmannin promotes the reaction [KN 93 inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK3 protein]]
KN 93 affects the reaction [Ptychodiscus brevis T2 toxin affects the phosphorylation of MAPK3 protein]
KN 93 inhibits the reaction [cadmium acetate results in increased phosphorylation of MAPK3 protein]; KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK3 protein]; KN 93 inhibits the reaction [diphenylditelluride results in increased phosphorylation of MAPK3 protein]; KN 93 inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased phosphorylation of MAPK3 protein]
CTD PMID:15086530, PMID:15355987, PMID:19233221, PMID:21879721, PMID:21933187, PMID:28181390, PMID:29883672 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:21933187 NCBI chr14:33,377,898...33,447,353
Ensembl chr14:33,377,898...33,447,158
JBrowse link
G Myh7 myosin, heavy polypeptide 7, cardiac muscle, beta multiple interactions ISO Curcumin promotes the reaction [KN 93 inhibits the reaction [Caffeine results in increased expression of MYH7 mRNA]]; KN 93 inhibits the reaction [Caffeine results in increased expression of MYH7 mRNA]; KN 93 promotes the reaction [Curcumin inhibits the reaction [Caffeine results in increased expression of MYH7 mRNA]] CTD PMID:25093688 NCBI chr14:54,970,684...54,994,626
Ensembl chr14:54,970,684...54,994,626
JBrowse link
G Nefl neurofilament, light polypeptide multiple interactions ISO KN 93 inhibits the reaction [diphenylditelluride results in increased phosphorylation of NEFL protein] CTD PMID:21879721 NCBI chr14:68,083,863...68,089,095
Ensembl chr14:68,083,863...68,089,095
JBrowse link
G Nefm neurofilament, medium polypeptide multiple interactions ISO KN 93 inhibits the reaction [diphenylditelluride results in increased phosphorylation of NEFM protein] CTD PMID:21879721 NCBI chr14:68,119,545...68,125,004
Ensembl chr14:68,082,590...68,124,846
JBrowse link
G Nfatc1 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 multiple interactions EXP KN 93 affects the reaction [[Cadmium co-treated with TNFSF11 protein co-treated with CSF1R protein] affects the expression of NFATC1 protein] CTD PMID:32522522 NCBI chr18:80,606,205...80,713,071
Ensembl chr18:80,606,205...80,713,071
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions ISO KN 93 inhibits the reaction [Phenylephrine results in increased degradation of NFKBIA protein] CTD PMID:15629441 NCBI chr12:55,489,409...55,492,647
Ensembl chr12:55,489,410...55,492,647
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation ISO KN 93 results in decreased phosphorylation of RB1 protein CTD PMID:15958590 NCBI chr14:73,192,858...73,325,951
Ensembl chr14:73,183,673...73,325,822
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 multiple interactions ISO KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21933187 NCBI chr11:86,498,869...86,544,885
Ensembl chr11:86,498,871...86,544,805
JBrowse link
G Src Rous sarcoma oncogene multiple interactions ISO KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of SRC protein] CTD PMID:19233221 NCBI chr 2:157,423,906...157,471,838
Ensembl chr 2:157,418,444...157,471,862
JBrowse link
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 multiple interactions EXP KN 93 affects the reaction [[Cadmium co-treated with TNFSF11 protein co-treated with CSF1R protein] affects the expression of ACP5 protein]; KN 93 affects the reaction [[Cadmium co-treated with TNFSF11 protein co-treated with CSF1R protein] affects the expression of NFATC1 protein]; KN 93 inhibits the reaction [TNFSF11 protein results in increased expression of CALCR mRNA] CTD PMID:21869564, PMID:32522522 NCBI chr14:78,277,446...78,308,043
Ensembl chr14:78,277,445...78,308,043
JBrowse link
G Vim vimentin multiple interactions ISO KN 93 inhibits the reaction [diphenylditelluride results in increased phosphorylation of VIM protein] CTD PMID:21879721 NCBI chr 2:13,574,311...13,582,826
Ensembl chr 2:13,573,927...13,582,826
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21538
    role 21517
      biological role 21516
        inhibitor 19287
          enzyme inhibitor 19203
            EC 2.* (transferase) inhibitor 14258
              EC 2.7.* (P-containing group transferase) inhibitor 13940
                EC 2.7.11.* (protein-serine/threonine kinase) inhibitor 8327
                  EC 2.7.11.17 (Ca(2+)/calmodulin-dependent protein kinase) inhibitor 53
                    2-cyclopentyl-4-[5-(3-methylphenyl)furo[2,3-b]pyridin-3-yl]benzoic acid 0
                    KN-93 53
Path 2
Term Annotations click to browse term
  CHEBI ontology 21538
    role 21517
      biological role 21516
        inhibitor 19287
          enzyme inhibitor 19203
            EC 2.* (transferase) inhibitor 14258
              EC 2.7.* (P-containing group transferase) inhibitor 13940
                protein kinase inhibitor 13402
                  EC 2.7.11.* (protein-serine/threonine kinase) inhibitor 8327
                    EC 2.7.11.17 (Ca(2+)/calmodulin-dependent protein kinase) inhibitor 53
                      2-cyclopentyl-4-[5-(3-methylphenyl)furo[2,3-b]pyridin-3-yl]benzoic acid 0
                      KN-93 53
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.