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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:EC 2.7.11.17 (Ca(2+)/calmodulin-dependent protein kinase) inhibitor
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Accession:CHEBI:131794 term browser browse the term
Definition:Any EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of a Ca(2+)/calmodulin-dependent protein kinase (EC 2.7.11.17).
Synonyms:related_synonym: ATP:caldesmon O-phosphotransferase inhibitor;   ATP:caldesmon O-phosphotransferase inhibitors;   ATP:protein phosphotransferase ((2+)/calmodulin-dependent) inhibitor;   ATP:protein phosphotransferase ((2+)/calmodulin-dependent) inhibitors;   CAM PKII inhibitor;   CAM PKII inhibitors;   Ca(2+)/calmodulin-dependent microtubule-associated protein 2 kinase inhibitor;   Ca(2+)/calmodulin-dependent microtubule-associated protein 2 kinase inhibitors;   Ca(2+)/calmodulin-dependent protein kinase (EC 2.7.11.17) inhibitors;   Ca(2+)/calmodulin-dependent protein kinase 1 inhibitor;   Ca(2+)/calmodulin-dependent protein kinase 1 inhibitors;   Ca(2+)/calmodulin-dependent protein kinase II inhibitor;   Ca(2+)/calmodulin-dependent protein kinase II inhibitors;   Ca(2+)/calmodulin-dependent protein kinase IV inhibitor;   Ca(2+)/calmodulin-dependent protein kinase IV inhibitors;   Ca(2+)/calmodulin-dependent protein kinase inhibitor;   Ca(2+)/calmodulin-dependent protein kinase inhibitors;   Ca(2+)/calmodulin-dependent protein kinase kinase beta inhibitor;   Ca(2+)/calmodulin-dependent protein kinase kinase beta inhibitors;   Ca(2+)/calmodulin-dependent protein kinase kinase inhibitor;   Ca(2+)/calmodulin-dependent protein kinase kinase inhibitors;   CaM kinase II inhibitor;   CaM kinase II inhibitors;   CaM kinase inhibitor;   CaM kinase inhibitors;   CaM-regulated serine/threonine kinase inhibitor;   CaM-regulated serine/threonine kinase inhibitors;   CaMKI inhibitor;   CaMKI inhibitors;   CaMKII inhibitor;   CaMKII inhibitors;   CaMKIV inhibitor;   CaMKIV inhibitors;   CaMKKalpha inhibitor;   CaMKKalpha inhibitors;   CaMKKbeta inhibitor;   CaMKKbeta inhibitors;   EC 2.7.11.17 inhibitor;   EC 2.7.11.17 inhibitors;   STK20 inhibitor;   STK20 inhibitors;   caldesmon kinase (phosphorylating) inhibitor;   caldesmon kinase (phosphorylating) inhibitors;   caldesmon kinase inhibitor;   caldesmon kinase inhibitors;   calmodulin-dependent kinase II inhibitor;   calmodulin-dependent kinase II inhibitors;   microtubule-associated protein 2 kinase inhibitor;   microtubule-associated protein 2 kinase inhibitors
 xref: Wikipedia:CAMK


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KN-93 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO KN 93 inhibits the reaction [Digoxin results in increased expression of ABCB1 protein]; KN 93 inhibits the reaction [Ouabain results in increased expression of ABCB1 protein] CTD PMID:19647009 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Aco1 aconitase 1 multiple interactions EXP KN 93 inhibits the reaction [Cadmium Chloride affects the localization of ACO1 protein] CTD PMID:25106854 NCBI chr 5:56,425,076...56,481,218
Ensembl chr 5:56,425,024...56,481,218
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant multiple interactions ISO KN 93 affects the reaction [[Cadmium co-treated with TNFSF11 protein co-treated with CSF1R protein] affects the expression of ACP5 protein] CTD PMID:32522522 NCBI chr 8:23,142,733...23,149,067
Ensembl chr 8:23,142,734...23,148,396
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO KN 93 inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of AHR protein] CTD PMID:18089838 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor multiple interactions ISO KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHRR mRNA] CTD PMID:18089838 NCBI chr 1:31,603,297...31,698,329
Ensembl chr 1:31,603,297...31,698,329
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions ISO KN 93 inhibits the reaction [Cadmium Chloride affects the localization of AIFM1 protein] CTD PMID:18506790 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP
ISO
KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein]
KN 93 inhibits the reaction [rutacarpine results in increased phosphorylation of AKT1 protein]
CTD PMID:19233221, PMID:21933187, PMID:28025122 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions EXP KN 93 inhibits the reaction [cadmium acetate results in increased expression of ATF4 protein] CTD PMID:29883672 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Calcr calcitonin receptor multiple interactions ISO KN 93 inhibits the reaction [TNFSF11 protein results in increased expression of CALCR mRNA] CTD PMID:21869564 NCBI chr 4:28,627,439...28,702,559
Ensembl chr 4:28,627,442...28,702,559
JBrowse link
G Camk1 calcium/calmodulin-dependent protein kinase I decreases activity ISO KN 93 results in decreased activity of CAMK1 protein CTD PMID:12193581 NCBI chr 4:145,289,300...145,300,146
Ensembl chr 4:145,288,996...145,300,177
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions ISO
EXP
[KN 93 co-treated with Losartan] inhibits the reaction [bisphenol A results in increased phosphorylation of CAMK2A protein]; KN 93 inhibits the reaction [bisphenol A results in increased phosphorylation of CAMK2A protein]
KN 93 inhibits the reaction [rutacarpine results in increased phosphorylation of CAMK2A protein]
KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of CAMK2A protein]; KN 93 inhibits the reaction [Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]]; KN 93 inhibits the reaction [Excitatory Amino Acid Agents promotes the reaction [CAMK2A protein binds to DRD3 protein]]; KN 93 inhibits the reaction [Ionomycin promotes the reaction [CAMK2A protein binds to DRD3 protein]]; KN 93 inhibits the reaction [Ionomycin promotes the reaction [CAMK2A protein modified form binds to DRD3 protein]]
CTD PMID:19217379, PMID:21933187, PMID:25103225, PMID:28025122 NCBI chr18:56,193,978...56,295,869
Ensembl chr18:56,193,978...56,295,869
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta multiple interactions EXP KN 93 inhibits the reaction [Cadmium affects the localization of CAMK2D protein] CTD PMID:22553113 NCBI chr 2:230,900,907...231,132,207
Ensembl chr 2:230,901,126...231,132,039
JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV multiple interactions EXP KN 93 inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of CAMK4 protein] CTD PMID:17973980 NCBI chr18:25,746,878...25,975,962
Ensembl chr18:25,749,098...25,965,957
JBrowse link
G Casp12 caspase 12 multiple interactions EXP KN 93 inhibits the reaction [cadmium acetate results in increased cleavage of CASP12 protein] CTD PMID:29883672 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp3 caspase 3 multiple interactions EXP
ISO
KN 93 inhibits the reaction [cadmium acetate results in increased cleavage of CASP3 protein]; KN 93 inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; KN 93 promotes the reaction [Cadmium Chloride results in increased cleavage of CASP3 protein]
KN 93 inhibits the reaction [rutecarpine inhibits the reaction [tert-Butylhydroperoxide results in increased activity of CASP3 protein]]
KN 93 inhibits the reaction [bisphenol A results in increased expression of and results in increased cleavage of CASP3 protein]; KN 93 inhibits the reaction [GW 7845 results in increased activity of CASP3 protein]
CTD PMID:19233221, PMID:20810541, PMID:26096086, PMID:26923100, PMID:28025122, PMID:29883672 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Ccl1 C-C motif chemokine ligand 1 multiple interactions ISO KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CCL1 mRNA] CTD PMID:18089838 NCBI chr10:69,534,976...69,537,836
Ensembl chr10:69,534,933...69,537,882
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO KN 93 results in decreased expression of CCND1 protein CTD PMID:15958590 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP KN 93 inhibits the reaction [Capsaicin results in increased phosphorylation of CREB1 protein]; KN 93 inhibits the reaction [Nicotine results in increased phosphorylation of CREB1 protein] CTD PMID:15385614, PMID:15631885, PMID:21113126 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions ISO KN 93 affects the reaction [[Cadmium co-treated with TNFSF11 protein co-treated with CSF1R protein] affects the expression of ACP5 protein]; KN 93 affects the reaction [[Cadmium co-treated with TNFSF11 protein co-treated with CSF1R protein] affects the expression of NFATC1 protein] CTD PMID:32522522 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO KN 93 inhibits the reaction [GW 7845 affects the localization of CYCS protein] CTD PMID:20810541 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 multiple interactions ISO KN 93 inhibits the reaction [Potassium results in increased expression of CYP11B2 mRNA] CTD PMID:12193581 NCBI chr 7:116,155,928...116,161,781
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO
EXP
KN 93 inhibits the reaction [STO 609 results in increased activity of CYP1A1 protein]; KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein] CTD PMID:18089838, PMID:18755850, PMID:23298284 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] CTD PMID:18089838 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions EXP KN 93 inhibits the reaction [cadmium acetate results in increased expression of DDIT3 protein] CTD PMID:29883672 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Drd3 dopamine receptor D3 multiple interactions EXP KN 93 inhibits the reaction [Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]]; KN 93 inhibits the reaction [Excitatory Amino Acid Agents promotes the reaction [CAMK2A protein binds to DRD3 protein]]; KN 93 inhibits the reaction [Ionomycin promotes the reaction [CAMK2A protein binds to DRD3 protein]]; KN 93 inhibits the reaction [Ionomycin promotes the reaction [CAMK2A protein modified form binds to DRD3 protein]]; KN 93 inhibits the reaction [Ionomycin results in increased phosphorylation of DRD3 protein] CTD PMID:19217379 NCBI chr11:61,819,102...61,883,223
Ensembl chr11:61,822,077...61,874,327
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions EXP KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EGFR protein] CTD PMID:19233221 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions EXP KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EIF4EBP1 protein] CTD PMID:21933187 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Foxo3 forkhead box O3 multiple interactions ISO KN 93 inhibits the reaction [Cadmium Chloride results in decreased activity of FOXO3 protein]; KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of FOXO3 protein] CTD PMID:23673518 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions EXP KN 93 inhibits the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein] CTD PMID:21879721 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 multiple interactions EXP KN 93 inhibits the reaction [Capsaicin results in increased phosphorylation of GRIA1 protein] CTD PMID:12019337 NCBI chr10:42,441,723...42,760,200
Ensembl chr10:42,614,713...42,760,200
JBrowse link
G Hdac5 histone deacetylase 5 multiple interactions ISO KN 93 inhibits the reaction [Potassium Chloride results in increased phosphorylation of HDAC5 protein] CTD PMID:17988634 NCBI chr10:90,140,183...90,169,853
Ensembl chr10:90,140,183...90,151,042
JBrowse link
G Hexb hexosaminidase subunit beta multiple interactions EXP KN 93 inhibits the reaction [Ionomycin results in increased secretion of HEXB protein] CTD PMID:14499669 NCBI chr 2:27,983,925...28,003,260
Ensembl chr 2:27,984,117...28,003,186
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions ISO KN 93 inhibits the reaction [Digoxin affects the localization of HIF1A protein]; KN 93 inhibits the reaction [Digoxin results in increased phosphorylation of HIF1A protein]; KN 93 inhibits the reaction [Ouabain affects the localization of HIF1A protein]; KN 93 inhibits the reaction [Ouabain results in increased phosphorylation of HIF1A protein] CTD PMID:19647009 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO KN 93 inhibits the reaction [rutacarpine results in increased expression of HMOX1 mRNA]; KN 93 inhibits the reaction [rutacarpine results in increased expression of HMOX1 protein] CTD PMID:28025122 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions EXP KN 93 inhibits the reaction [cadmium acetate results in increased expression of HSPA5 protein] CTD PMID:29883672 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of IL1B mRNA] CTD PMID:18089838 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Itgb7 integrin subunit beta 7 multiple interactions ISO KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of ITGB7 mRNA] CTD PMID:18089838 NCBI chr 7:143,820,236...143,837,802
Ensembl chr 7:143,820,900...143,837,780
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 multiple interactions EXP KN 93 inhibits the reaction [Phenylephrine results in increased activity of MAP3K5 protein] CTD PMID:15629441 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO
EXP
KN 93 inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK1 protein]; KN 93 promotes the reaction [wortmannin inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK1 protein]]; wortmannin promotes the reaction [KN 93 inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK1 protein]]
KN 93 affects the reaction [Ptychodiscus brevis T2 toxin affects the phosphorylation of MAPK1 protein]
KN 93 inhibits the reaction [cadmium acetate results in increased phosphorylation of MAPK1 protein]; KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK1 protein]; KN 93 inhibits the reaction [diphenylditelluride results in increased phosphorylation of MAPK1 protein]; KN 93 inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased phosphorylation of MAPK1 protein]
CTD PMID:15086530, PMID:15355987, PMID:19233221, PMID:21879721, PMID:21933187, PMID:28181390, PMID:29883672 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions EXP KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK14 protein] CTD PMID:21933187 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO
EXP
KN 93 inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK3 protein]; KN 93 promotes the reaction [wortmannin inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK3 protein]]; wortmannin promotes the reaction [KN 93 inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK3 protein]]
KN 93 affects the reaction [Ptychodiscus brevis T2 toxin affects the phosphorylation of MAPK3 protein]
KN 93 inhibits the reaction [cadmium acetate results in increased phosphorylation of MAPK3 protein]; KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK3 protein]; KN 93 inhibits the reaction [diphenylditelluride results in increased phosphorylation of MAPK3 protein]; KN 93 inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased phosphorylation of MAPK3 protein]
CTD PMID:15086530, PMID:15355987, PMID:19233221, PMID:21879721, PMID:21933187, PMID:28181390, PMID:29883672 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:21933187 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Myh7 myosin heavy chain 7 multiple interactions EXP Curcumin promotes the reaction [KN 93 inhibits the reaction [Caffeine results in increased expression of MYH7 mRNA]]; KN 93 inhibits the reaction [Caffeine results in increased expression of MYH7 mRNA]; KN 93 promotes the reaction [Curcumin inhibits the reaction [Caffeine results in increased expression of MYH7 mRNA]] CTD PMID:25093688 NCBI chr15:33,605,769...33,657,761
Ensembl chr15:33,634,422...33,656,089
JBrowse link
G Nefl neurofilament light multiple interactions EXP KN 93 inhibits the reaction [diphenylditelluride results in increased phosphorylation of NEFL protein] CTD PMID:21879721 NCBI chr15:44,799,378...44,803,251
Ensembl chr15:44,799,334...44,804,574
JBrowse link
G Nefm neurofilament medium multiple interactions EXP KN 93 inhibits the reaction [diphenylditelluride results in increased phosphorylation of NEFM protein] CTD PMID:21879721 NCBI chr15:44,855,307...44,860,604
Ensembl chr15:44,855,310...44,860,604
JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 multiple interactions ISO KN 93 affects the reaction [[Cadmium co-treated with TNFSF11 protein co-treated with CSF1R protein] affects the expression of NFATC1 protein] CTD PMID:32522522 NCBI chr18:77,203,517...77,322,690
Ensembl chr18:77,203,525...77,322,690
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP KN 93 inhibits the reaction [Phenylephrine results in increased degradation of NFKBIA protein] CTD PMID:15629441 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation ISO KN 93 results in decreased phosphorylation of RB1 protein CTD PMID:15958590 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions EXP KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21933187 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions EXP KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of SRC protein] CTD PMID:19233221 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO KN 93 affects the reaction [[Cadmium co-treated with TNFSF11 protein co-treated with CSF1R protein] affects the expression of ACP5 protein]; KN 93 affects the reaction [[Cadmium co-treated with TNFSF11 protein co-treated with CSF1R protein] affects the expression of NFATC1 protein]; KN 93 inhibits the reaction [TNFSF11 protein results in increased expression of CALCR mRNA] CTD PMID:21869564, PMID:32522522 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704
JBrowse link
G Vim vimentin multiple interactions EXP KN 93 inhibits the reaction [diphenylditelluride results in increased phosphorylation of VIM protein] CTD PMID:21879721 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      biological role 19764
        inhibitor 18247
          enzyme inhibitor 18173
            EC 2.* (transferase) inhibitor 13825
              EC 2.7.* (P-containing group transferase) inhibitor 13505
                EC 2.7.11.* (protein-serine/threonine kinase) inhibitor 8168
                  EC 2.7.11.17 (Ca(2+)/calmodulin-dependent protein kinase) inhibitor 52
                    2-cyclopentyl-4-[5-(3-methylphenyl)furo[2,3-b]pyridin-3-yl]benzoic acid 0
                    KN-93 52
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      biological role 19764
        inhibitor 18247
          enzyme inhibitor 18173
            EC 2.* (transferase) inhibitor 13825
              EC 2.7.* (P-containing group transferase) inhibitor 13505
                protein kinase inhibitor 13032
                  EC 2.7.11.* (protein-serine/threonine kinase) inhibitor 8168
                    EC 2.7.11.17 (Ca(2+)/calmodulin-dependent protein kinase) inhibitor 52
                      2-cyclopentyl-4-[5-(3-methylphenyl)furo[2,3-b]pyridin-3-yl]benzoic acid 0
                      KN-93 52
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.