Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


Term:tyrphostin B42
go back to main search page
Accession:CHEBI:131968 term browser browse the term
Definition:A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enoic acid with the amino group of benzylamine.
Synonyms:exact_synonym: (2E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide
 related_synonym: AG 490;   AG490;   Formula=C17H14N2O3;   InChI=1S/C17H14N2O3/c18-10-14(8-13-6-7-15(20)16(21)9-13)17(22)19-11-12-4-2-1-3-5-12/h1-9,20-21H,11H2,(H,19,22)/b14-8+;   InChIKey=TUCIOBMMDDOEMM-RIYZIHGNSA-N;   SMILES=C=1(C=CC(=CC1O)/C=C(/C(NCC=2C=CC=CC2)=O)\\C#N)O
 xref: PMID:10929036 "Europe PMC";   PMID:26190257 "Europe PMC";   PMID:26438799 "Europe PMC";   PMID:26487394 "Europe PMC";   PMID:26750536 "Europe PMC";   PMID:26919242 "Europe PMC";   PMID:27011172 "Europe PMC";   PMID:27044832 "Europe PMC";   PMID:27101310 "Europe PMC";   PMID:27107220 "Europe PMC";   PMID:27274711 "Europe PMC";   Reaxys:4323263 "Reaxys"

show annotations for term's descendants       view all columns           Sort by:
tyrphostin B42 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:18337263

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19764
    role 19711
      chemical role 19227
        antioxidant 14142
          tyrphostin B42 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19764
    subatomic particle 19762
      composite particle 19762
        hadron 19762
          baryon 19762
            nucleon 19762
              atomic nucleus 19762
                atom 19762
                  main group element atom 19646
                    p-block element atom 19646
                      carbon group element atom 19540
                        carbon atom 19529
                          organic molecular entity 19529
                            organic group 18432
                              organic divalent group 18423
                                organodiyl group 18423
                                  carbonyl group 18311
                                    carbonyl compound 18311
                                      carboxylic acid 17978
                                        carboacyl group 17095
                                          univalent carboacyl group 17095
                                            carbamoyl group 16817
                                              carboxamide 16817
                                                alpha,beta-unsaturated carboxylic acid amide 4756
                                                  enamide 4756
                                                    tyrphostin B42 1
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.