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Accession:CHEBI:133068 term browser browse the term
Definition:An eight-membered oligopeptide comprising Arg, Pro, Pro, Gly, Phe, Ser, Pro and Phe residues joined in sequence. It is an analogue of bradykinin lacking the Arg residue at position 9.
Synonyms:exact_synonym: L-arginyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanine
 related_synonym: 1-8-Bradykinin;   9-De-arg-bradykinin;   9-Des-arg-BK;   9-de-L-Argininebradykinin;   Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe;   Formula=C44H61N11O10;   InChI=1S/C44H61N11O10/c45-29(15-7-19-48-44(46)47)40(61)55-22-10-18-35(55)42(63)54-21-8-16-33(54)38(59)49-25-36(57)50-30(23-27-11-3-1-4-12-27)37(58)52-32(26-56)41(62)53-20-9-17-34(53)39(60)51-31(43(64)65)24-28-13-5-2-6-14-28/h1-6,11-14,29-35,56H,7-10,15-26,45H2,(H,49,59)(H,50,57)(H,51,60)(H,52,58)(H,64,65)(H4,46,47,48)/t29-,30-,31-,32-,33-,34-,35-/m0/s1;   InChIKey=VCEHWDBVPZFHAG-POFDKVPJSA-N;   L-Arg-L-Pro-L-Pro-Gly-L-Phe-L-Ser-L-Pro-L-Phe;   RPPGFSPF;   SMILES=C(=N)(NCCC[C@@H](C(=O)N1[C@H](C(N2[C@H](C(=O)NCC(N[C@H](C(N[C@H](C(=O)N3[C@H](C(=O)N[C@H](C(O)=O)CC=4C=CC=CC4)CCC3)CO)=O)CC=5C=CC=CC5)=O)CCC2)=O)CCC1)N)N
 xref: CAS:15958-92-6 "ChemIDplus"
 xref_mesh: MESH:C024626
 xref: PMID:23318500 "Europe PMC";   PMID:23742018 "Europe PMC";   Reaxys:10326223 "Reaxys";   Reaxys:4228002 "Reaxys"
 cyclic_relationship: is_conjugate_base_of CHEBI:133069

show annotations for term's descendants       view all columns           Sort by:
[des-Arg(9)]-bradykinin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bdkrb1 bradykinin receptor B1 JBrowse link 6 129,437,423 129,441,553 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Tnfrsf1a TNF receptor superfamily member 1A JBrowse link 4 157,864,905 157,877,634 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    chemical entity 19726
      group 19641
        organic group 18413
          amino-acid residue 9317
            peptide 9316
              oligopeptide 1075
                [des-Arg(9)]-bradykinin 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic group 18413
                              organic divalent group 18404
                                organodiyl group 18404
                                  carbonyl group 18293
                                    carbonyl compound 18293
                                      carboxylic acid 17960
                                        carboacyl group 17072
                                          univalent carboacyl group 17072
                                            carbamoyl group 16801
                                              carboxamide 16801
                                                peptide 9316
                                                  oligopeptide 1075
                                                    [des-Arg(9)]-bradykinin 3
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.