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Accession:CHEBI:133818 term browser browse the term
Definition:A member of the class of phenylureas that is a potent inhibitor of salt-inducible kinase 2, a potential target protein for therapy in ovarian cancer.
Synonyms:exact_synonym: N-(2,4-dimethoxyphenyl)-N'-(2,6-dimethylphenyl)-N-{6-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl}urea
 related_synonym: Formula=C32H37N7O3;   InChI=1S/C32H37N7O3/c1-22-7-6-8-23(2)31(22)36-32(40)39(27-14-13-26(41-4)19-28(27)42-5)30-20-29(33-21-34-30)35-24-9-11-25(12-10-24)38-17-15-37(3)16-18-38/h6-14,19-21H,15-18H2,1-5H3,(H,36,40)(H,33,34,35);   InChIKey=UYUHRKLITDJEHB-UHFFFAOYSA-N;   SMILES=N(C1=C(C=C(C=C1)OC)OC)(C=2C=C(NC3=CC=C(C=C3)N4CCN(CC4)C)N=CN2)C(NC5=C(C=CC=C5C)C)=O
 xref: PMID:24745372;   PMID:25088745;   PMID:25114223;   PMID:26590148;   PMID:27224444;   PMID:27478041;   Reaxys:24079892

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  CHEBI ontology 19790
    role 19738
      application 19385
        pharmaceutical 19254
          drug 19254
            antineoplastic agent 16919
              HG-9-91-01 0
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  CHEBI ontology 19790
    subatomic particle 19788
      composite particle 19788
        hadron 19788
          baryon 19788
            nucleon 19788
              atomic nucleus 19788
                atom 19788
                  main group element atom 19674
                    p-block element atom 19674
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic group 18475
                              organic divalent group 18468
                                organodiyl group 18468
                                  carbonyl group 18366
                                    carbonyl compound 18366
                                      carboxylic acid 18034
                                        carboacyl group 17190
                                          univalent carboacyl group 17190
                                            carbamoyl group 16928
                                              carboxamide 16928
                                                monocarboxylic acid amide 14575
                                                  urea 4989
                                                    ureas 4987
                                                      phenylureas 1979
                                                        HG-9-91-01 0
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