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ONTOLOGY REPORT - ANNOTATIONS


Term:saroglitazar
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Accession:CHEBI:134708 term browser browse the term
Definition:A monocarboxylic acid that is (2S)-2-ethoxy-3-(p-ethoxyphenyl)propanoic acid in which one of the methyl hydrogens of the p-ethoxy substituent has been replaced by the nitrogen of 2-methyl-5-[4-(methylthio)phenyl]-1H-pyrrole. An agonist at the subtypes alpha and gamma of the peroxisome proliferator-activated receptor (PPAR) with predominant PPARalpha activity, it is used in the treatment of type 2 diabetes.
Synonyms:exact_synonym: (2S)-2-ethoxy-3-[4-(2-{2-methyl-5-[4-(methylthio)phenyl]-1H-pyrrol-1-yl}ethoxy)phenyl]propanoic acid
 related_synonym: Formula=C25H29NO4S;   InChI=1S/C25H29NO4S/c1-4-29-24(25(27)28)17-19-6-10-21(11-7-19)30-16-15-26-18(2)5-14-23(26)20-8-12-22(31-3)13-9-20/h5-14,24H,4,15-17H2,1-3H3,(H,27,28)/t24-/m0/s1;   InChIKey=MRWFZSLZNUJVQW-DEOSSOPVSA-N;   SMILES=C1=C(C=CC(=C1)C[C@@H](C(O)=O)OCC)OCCN2C(=CC=C2C)C=3C=CC(=CC3)SC;   lipaglyn;   saroglitazarum
 xref: CAS:495399-09-2;   Drug_Central:5047;   PMID:23906191;   PMID:24062180;   PMID:25674933;   PMID:25820041;   PMID:25820046;   PMID:25926748;   PMID:26171220;   PMID:27187607;   PMID:27666920;   Reaxys:11765048;   Wikipedia:Saroglitazar


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  CHEBI ontology 19770
    role 19717
      application 19363
        pharmaceutical 19233
          drug 19233
            hypoglycemic agent 4004
              saroglitazar 0
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  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19655
                    p-block element atom 19655
                      carbon group element atom 19548
                        carbon atom 19537
                          organic molecular entity 19537
                            organic group 18451
                              organic divalent group 18445
                                organodiyl group 18445
                                  carbonyl group 18346
                                    carbonyl compound 18346
                                      carboxylic acid 18019
                                        monocarboxylic acid 17277
                                          saroglitazar 0
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