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Term:VX nerve agent
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Accession:CHEBI:136185 term browser browse the term
Definition:A organic thiophosphate that is the ethyl ester of S-{2-[di(propan-2-yl)amino]ethyl} O hydrogen methylphosphonothioate. A toxic nerve agent used in chemical warfare.
Synonyms:exact_synonym: S-{2-[di(propan-2-yl)amino]ethyl} O-ethyl methylphosphonothioate
 related_synonym: Ethyl S-2-diisopropylaminoethyl methylphosphonothiolate;   Ethyl-S-diisopropylaminoethyl methylthiophosphonate;   Formula=C11H26NO2PS;   InChI=1S/C11H26NO2PS/c1-7-14-15(6,13)16-9-8-12(10(2)3)11(4)5/h10-11H,7-9H2,1-6H3;   InChIKey=JJIUCEJQJXNMHV-UHFFFAOYSA-N;   O-Ethyl S-(2-diisopropylaminoethyl) methylphosphonothioate;   O-ethyl-S-[2-(N,N-diisopropylamino)ethyl] ester;   S-(2-Diisopropylaminoethyl) O-ethyl methyl phosphonothiolate;   SMILES=CC(N(CCSP(OCC)(=O)C)C(C)C)C;   VX
 xref: CAS:50782-69-9 "ChemIDplus";   CAS:50782-69-9 "NIST Chemistry WebBook";   Chemspider:36386 "SUBMITTER"
 xref_mesh: MESH:C009680
 xref: PMID:20947456 "Europe PMC";   PMID:21862421 "Europe PMC";   PMID:21905719 "Europe PMC";   PMID:22042427 "Europe PMC";   PMID:23083335 "Europe PMC";   PMID:23126561 "Europe PMC";   PMID:23402290 "Europe PMC";   PMID:23872337 "Europe PMC";   PMID:24517492 "Europe PMC";   PMID:24633585 "Europe PMC";   PMID:24766293 "Europe PMC";   PMID:24854058 "Europe PMC";   PMID:24972874 "Europe PMC";   PMID:26327407 "Europe PMC";   PMID:26561750 "Europe PMC";   PMID:27113675 "Europe PMC";   PMID:27594690 "Europe PMC";   PMID:27627873 "Europe PMC";   PMID:28098192 "Europe PMC";   PMID:28179194 "Europe PMC";   PMID:28267914 "Europe PMC";   Reaxys:1949015 "Reaxys";   Wikipedia:VX_(nerve_agent)

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VX nerve agent term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ache acetylcholinesterase JBrowse link 12 22,472,358 22,477,052 RGD:6480464
G Bche butyrylcholinesterase JBrowse link 2 171,104,476 171,196,186 RGD:6480464
G Bdnf brain-derived neurotrophic factor JBrowse link 3 100,768,637 100,819,216 RGD:6480464
G Chrm2 cholinergic receptor, muscarinic 2 JBrowse link 4 64,089,028 64,091,090 RGD:6480464
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 JBrowse link 1 141,874,354 141,893,674 RGD:6480464
G Krt10 keratin 10 JBrowse link 10 87,296,445 87,301,307 RGD:6480464
G Pepd peptidase D JBrowse link 1 90,820,670 91,285,128 RGD:6480464
G Pon1 paraoxonase 1 JBrowse link 4 30,249,749 30,276,297 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19734
    role 19680
      biological role 19678
        aetiopathogenetic role 18782
          neurotoxin 17364
            VX nerve agent 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19734
    subatomic particle 19730
      composite particle 19730
        hadron 19730
          baryon 19730
            nucleon 19730
              atomic nucleus 19730
                atom 19730
                  main group element atom 19614
                    p-block element atom 19614
                      chalcogen 19323
                        oxygen atom 19284
                          oxygen molecular entity 19284
                            hydroxides 19042
                              oxoacid 18106
                                pnictogen oxoacid 9849
                                  phosphorus oxoacid 8671
                                    phosphoric acids 7340
                                      phosphoric acid 7340
                                        phosphoric acid derivative 6991
                                          phosphate 6991
                                            organic phosphate 6990
                                              organic thiophosphate 2796
                                                VX nerve agent 9
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.