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ONTOLOGY REPORT - ANNOTATIONS


Term:etazolate
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Accession:CHEBI:138502 term browser browse the term
Definition:A pyrazolopyridine that is 1H-pyrazolo[3,4-b]pyridine which is substituted at positions 1, 4, and 5 by ethyl, 2-isopropylidenehydrazino, and ethoxycarbonyl groups, respectively. A phosphodiesterase IV inhibitor with antidepressant and anxiolytic properties.
Synonyms:exact_synonym: ethyl 1-ethyl-4-(2-isopropylidenehydrazino)-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
 related_synonym: 1-ethyl-4-(2-propan-2-ylidenehydrazinyl)-5-pyrazolo[3,4-b]pyridinecarboxylic acid ethyl ester;   1H-pyrazolo(3,4-b)pyridine-5-carboxylic acid, 1-ethyl-4-((1-methylethylidene)hydrazino)-, ethyl ester;   EHT-0202;   Formula=C14H19N5O2;   InChI=1S/C14H19N5O2/c1-5-19-13-10(8-16-19)12(18-17-9(3)4)11(7-15-13)14(20)21-6-2/h7-8H,5-6H2,1-4H3,(H,15,18);   InChIKey=OPQRBXUBWHDHPQ-UHFFFAOYSA-N;   SMILES=CCN1C2=NC=C(C(=C2C=N1)NN=C(C)C)C(=O)OCC;   SQ-20,009;   etazolato;   etazolatum;   ethyl 1-ethyl-4-(2-isopropylidenehydrazino)pyrazolo[3,4-b]pyridine-5-carboxylate;   ethyl 1-ethyl-4-(2-propan-2-ylidenehydrazinyl)pyrazolo[3,4-b]pyridine-5-carboxylate;   ethyl 1-ethyl-4-(2-propan-2-ylidenehydrazinyl)pyrazolo[4,5-e]pyridine-5-carboxylate;   ethyl 1-ethyl-4-[2-(1-methylethylidene)hydrazino]-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
 alt_id: CHEBI:93135
 xref: CAS:51022-77-6 "ChemIDplus";   Chemspider:3162 "SUBMITTER";   LINCS:LSM-3446
 xref_mesh: MESH:D004974
 xref: PMID:18397369 "SUBMITTER";   PMID:20223232 "Europe PMC";   PMID:22698578 "Europe PMC";   PMID:23178198 "Europe PMC";   PMID:23384434 "Europe PMC";   PMID:23926692 "Europe PMC";   PMID:23974048 "Europe PMC";   PMID:24434771 "Europe PMC";   PMID:24705918 "Europe PMC";   PMID:25120105 "Europe PMC";   PMID:25136630 "Europe PMC";   PMID:27988361 "Europe PMC";   PMID:449623 "SUBMITTER";   PMID:6131949 "Europe PMC";   PMID:6132997 "SUBMITTER";   PMID:6991258 "Europe PMC";   Pubchem:3277 "SUBMITTER";   Reaxys:548872 "Reaxys";   Wikipedia:Etazolate


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etazolate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:6480464
G Ltc4s leukotriene C4 synthase JBrowse link 10 35,736,486 35,743,088 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19614
    role 19557
      biological role 19550
        pharmacological role 18676
          neurotransmitter agent 16228
            GABA agent 15414
              etazolate 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19614
    subatomic particle 19610
      composite particle 19610
        hadron 19610
          baryon 19610
            nucleon 19610
              atomic nucleus 19610
                atom 19610
                  main group element atom 19489
                    p-block element atom 19489
                      chalcogen 19201
                        oxygen atom 19155
                          oxygen molecular entity 19155
                            hydroxides 18944
                              organic hydroxy compound 18464
                                alcohol 14771
                                  primary alcohol 13738
                                    ethanols 7926
                                      ethanol 7926
                                        ethyl ester 3054
                                          etazolate 2
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