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Term:(5Z,8Z,11Z,14Z,16E,18R)-18-hydroperoxyicosapentaenoic acid
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Accession:CHEBI:138565 term browser browse the term
Definition:A hydroperoxyicosapentaenoic acid that is (5Z,8Z,11Z,14Z,16E)-icosapentaenoic acid in which the pro-R hydrogen at position 18 has been replaced by a hydroperoxy group. One of the two stereoisomers formed when acetylated COX2 oxidises the omega-3 fatty acid EPA.
Synonyms:exact_synonym: (18R)-HpEPE;   (5Z,8Z,11Z,14Z,16E,18R)-18-hydroperoxyicosa-5,8,11,14,16-pentaenoic acid;   18(R)-HpEPE
 related_synonym: Formula=C20H30O4;   InChI=1S/C20H30O4/c1-2-19(24-23)17-15-13-11-9-7-5-3-4-6-8-10-12-14-16-18-20(21)22/h4-7,10-13,15,17,19,23H,2-3,8-9,14,16,18H2,1H3,(H,21,22)/b6-4-,7-5-,12-10-,13-11-,17-15+/t19-/m1/s1;   InChIKey=ZNUBMQUXCKZUTC-UAAZXLHOSA-N;   SMILES=[C@@H](CC)(/C=C/C=C\\C/C=C\\C/C=C\\C/C=C\\CCCC(=O)O)OO
 xref: Reaxys:14535261 "Reaxys"

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  CHEBI ontology 19654
    role 19598
      application 19220
        pharmaceutical 19081
          drug 19081
            antineoplastic agent 16550
              all-cis-5,8,11,14,17-icosapentaenoic acid 0
                (5Z,8Z,11Z,14Z,16E,18R)-18-hydroperoxyicosapentaenoic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    p-block element atom 19531
                      carbon group element atom 19413
                        carbon atom 19405
                          organic molecular entity 19405
                            organic group 18331
                              organic divalent group 18321
                                organodiyl group 18321
                                  carbonyl group 18209
                                    carbonyl compound 18209
                                      carboxylic acid 17908
                                        monocarboxylic acid 17245
                                          fatty acid 15807
                                            unsaturated fatty acid 888
                                              polyunsaturated fatty acid 646
                                                essential fatty acid 374
                                                  omega-3 fatty acid 62
                                                    all-cis-5,8,11,14,17-icosapentaenoic acid 0
                                                      (5Z,8Z,11Z,14Z,16E,18R)-18-hydroperoxyicosapentaenoic acid 0
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