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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:3,4-dihydroxyphenylethyleneglycol
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Accession:CHEBI:1387 term browser browse the term
Definition:A tetrol composed of ethyleneglycol having a 3,4-dihydroxyphenyl group at the 1-position.
Synonyms:exact_synonym: 4-(1,2-dihydroxyethyl)benzene-1,2-diol
 related_synonym: (3,4-dihydroxyphenyl)ethylene glycol;   1-(3,4-dihydroxyphenyl)-1,2-ethanediol;   2-hydroxy-2-(3,4-dihydroxy)phenylethanol;   3,4-Dihydroxyphenylglycol;   3,4-dihydroxyphenethyl glycol;   3,4-dihydroxyphenylethyl glycol;   DHPG;   DOPEG;   Dihydroxyphenylethylene glycol;   Formula=C8H10O4;   InChI=1S/C8H10O4/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8-12H,4H2;   InChIKey=MTVWFVDWRVYDOR-UHFFFAOYSA-N;   SMILES=OCC(O)c1ccc(O)c(O)c1;   beta,3,4-trihydroxy phenethyl alcohol
 xref: CAS:3343-19-9;   HMDB:HMDB0000318;   KEGG:C05576
 xref_mesh: MESH:C010117
 xref: MetaCyc:CPD-11878;   PMID:11479664;   PMID:16218695;   PMID:16819902;   PMID:22770225;   PMID:2468969;   PMID:2645784;   PMID:2907005;   PMID:3161030;   PMID:4091997;   PMID:6146669;   PMID:6497782;   PMID:6671452;   PMID:6875564;   PMID:7176821;   Reaxys:2210995


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3,4-dihydroxyphenylethyleneglycol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase increases methylation ISO COMT protein results in increased methylation of 3,4-dihydroxyphenylglycol CTD PMID:11160877 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Mgll monoglyceride lipase affects response to substance ISO MGLL protein affects the susceptibility to 3,4-dihydroxyphenylglycol CTD PMID:21911610 NCBI chr 4:120,671,436...120,773,458
Ensembl chr 4:120,671,489...120,771,088
JBrowse link
G Plcb1 phospholipase C beta 1 multiple interactions
increases activity
EXP [3,4-dihydroxyphenylglycol co-treated with Guanosine 5'-O-(3-Thiotriphosphate)] results in increased activity of PLCB1 protein; Caffeine inhibits the reaction [3,4-dihydroxyphenylglycol results in increased activity of PLCB1 protein]; Caffeine inhibits the reaction [[3,4-dihydroxyphenylglycol co-treated with Guanosine 5'-O-(3-Thiotriphosphate)] results in increased activity of PLCB1 protein]; Theophylline inhibits the reaction [3,4-dihydroxyphenylglycol results in increased activity of PLCB1 protein]; Theophylline inhibits the reaction [[3,4-dihydroxyphenylglycol co-treated with Guanosine 5'-O-(3-Thiotriphosphate)] results in increased activity of PLCB1 protein] CTD PMID:15998294 NCBI chr 3:127,721,244...128,419,565
Ensembl chr 3:128,155,069...128,419,545
JBrowse link

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Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        biochemical role 19282
          metabolite 19263
            3,4-dihydroxyphenylethyleneglycol 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic molecule 19488
                              organic cyclic compound 19285
                                organic aromatic compound 19119
                                  phenols 18112
                                    benzenediols 6020
                                      catechols 3157
                                        3,4-dihydroxyphenylethyleneglycol 3
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