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Accession:CHEBI:138889 term browser browse the term
Definition:A non-proteinogenic L-alpha-amino acid that is L-norleucine which is substituted at position 5 by an oxo group and at position 6 by a diazo group. It is as inhibitor of various glutamine-utilising enzymes.
Synonyms:related_synonym: (S)-2-amino-6-diazo-5-oxocaproic acid;   Formula=C6H9N3O3;   InChI=1S/C6H9N3O3/c7-5(6(11)12)2-1-4(10)3-9-8/h3,5H,1-2,7H2,(H,11,12)/t5-/m0/s1;   InChIKey=YCWQAMGASJSUIP-YFKPBYRVSA-N;   L-DON;   SMILES=C(=O)(O)[C@H](CCC(C=[N+]=[N-])=O)N;   diazooxonorleucine
 xref: Beilstein:1725815 "SUBMITTER";   CAS:157-03-9 "ChemIDplus";   MetaCyc:CPD0-1627;   PMID:1412455 "Europe PMC";   PMID:2108451 "Europe PMC";   PMID:25584882 "Europe PMC";   PMID:26425550 "Europe PMC";   PMID:27489275 "Europe PMC";   PMID:27560860 "Europe PMC";   PMID:28454342 "Europe PMC";   PMID:28552037 "Europe PMC";   PMID:28759224 "Europe PMC";   PMID:909432 "Europe PMC";   Pubchem:24893639 "SUBMITTER";   Wikipedia:6-Diazo-5-oxo-L-norleucine

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  CHEBI ontology 19654
    role 19598
      biological role 19596
        antimicrobial agent 17143
          antiviral agent 3604
            6-diazo-5-oxo-L-norleucine 0
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  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    p-block element atom 19531
                      carbon group element atom 19413
                        carbon atom 19405
                          organic molecular entity 19405
                            organic group 18331
                              organic divalent group 18321
                                organodiyl group 18321
                                  carbonyl group 18209
                                    carbonyl compound 18209
                                      carboxylic acid 17908
                                        amino acid 12306
                                          alpha-amino acid 7423
                                            L-alpha-amino acid 7080
                                              non-proteinogenic L-alpha-amino acid 577
                                                6-diazo-5-oxo-L-norleucine 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.