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ONTOLOGY REPORT - ANNOTATIONS


Term:S-nitroso-L-cysteine
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Accession:CHEBI:138935 term browser browse the term
Definition:An L-cysteine derivative in which the sulfur atom carries a nitroso substituent. A cell-permeable low-molecular-weight nitrosothiol and nitric oxide donor.
Synonyms:related_synonym: CysNO;   Formula=C3H6N2O3S;   InChI=1S/C3H6N2O3S/c4-2(3(6)7)1-9-5-8/h2H,1,4H2,(H,6,7)/t2-/m0/s1;   InChIKey=XOWVFANEOZMPKG-REOHCLBHSA-N;   L-CysSNO;   NO-L-cysteine;   NO-cysteine;   Nitrosocysteine;   S-Nitrosocysteine;   SMILES=C([C@@H](N)CSN=O)(=O)O
 alt_id: CHEBI:45691
 xref: CAS:51209-75-7
 xref_mesh: MESH:C021315
 xref: PDBeChem:SNC;   PMID:22304688;   PMID:26444682;   PMID:26686469;   PMID:27064847;   PMID:27126574;   PMID:28081246;   PMID:28381519;   PMID:28440386;   PMID:28600633;   PMID:28764371;   Reaxys:3538115


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S-nitroso-L-cysteine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARRB2 arrestin beta 2 JBrowse link 17 4,710,619 4,721,500 RGD:6480464
G CASP3 caspase 3 JBrowse link 4 184,627,696 184,649,475 RGD:6480464
G GRK2 G protein-coupled receptor kinase 2 JBrowse link 11 67,266,420 67,286,556 RGD:6480464
G MGST1 microsomal glutathione S-transferase 1 JBrowse link 12 16,347,142 16,377,192 RGD:6480464
G SIRT1 sirtuin 1 JBrowse link 10 67,884,656 67,918,390 RGD:6480464
G TP53 tumor protein p53 JBrowse link 17 7,668,402 7,687,550 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 23948
    role 23836
      application 23245
        pharmaceutical 22803
          drug 22803
            hematologic agent 4400
              S-nitroso-L-cysteine 6
                S-nitroso-L-cysteine residue 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 23948
    subatomic particle 23899
      composite particle 23899
        hadron 23899
          baryon 23899
            nucleon 23899
              atomic nucleus 23899
                atom 23899
                  main group element atom 23720
                    p-block element atom 23720
                      carbon group element atom 23436
                        carbon atom 23392
                          organic molecular entity 23392
                            organic group 22058
                              organic divalent group 22032
                                organodiyl group 22032
                                  carbonyl group 22007
                                    carbonyl compound 22007
                                      carboxylic acid 21059
                                        amino acid 13086
                                          alpha-amino acid 7939
                                            L-alpha-amino acid 7595
                                              serine family amino acid 1774
                                                L-cysteine 1100
                                                  L-cysteine derivative 1087
                                                    S-nitroso-L-cysteine 6
                                                      S-nitroso-L-cysteine residue 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.