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Accession:CHEBI:138974 term browser browse the term
Definition:A tetracyclic triterpenoid that is cucurbitadienol in which the side-chain double bond (position 24-25) has undergone formal oxidation to introduce hydroxy groups at positions 24 and 25 (the 24R stereoisomer). It is a biometabolite of mogrosides found in Siraitia grosvenorii.
Synonyms:exact_synonym: (1S,4R,9beta,11alpha,24R)-9,10,14-trimethyl-4,9-cyclo-9,10-secocholest-5-ene-1,11,24,25-tetrol
 related_synonym: (24R)-cucurbit-5-ene-3beta,11alpha,24,25-tetraol;   Formula=C30H52O4;   InChI=1S/C30H52O4/c1-18(9-13-24(32)27(4,5)34)19-15-16-28(6)22-12-10-20-21(11-14-23(31)26(20,2)3)30(22,8)25(33)17-29(19,28)7/h10,18-19,21-25,31-34H,9,11-17H2,1-8H3/t18-,19-,21-,22+,23+,24-,25-,28+,29-,30+/m1/s1;   InChIKey=JLYBBRAAICDTIS-AYEHCKLZSA-N;   SMILES=[C@@]12(C)[C@]3([C@]([C@@]4(CC[C@@H](C(C4=CC3)(C)C)O)[H])([C@@H](C[C@]2(C)[C@](CC1)([C@@H](CC[C@H](C(C)(C)O)O)C)[H])O)C)[H]
 xref: MetaCyc:CPD-20463;   PMID:11809458 "Europe PMC";   PMID:12405766 "Europe PMC";   PMID:25759326 "SUBMITTER";   PMID:26101699 "Europe PMC";   PMID:27583359 "SUBMITTER";   PMID:27884874 "Europe PMC";   Reaxys:9101900 "Reaxys"

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  CHEBI ontology 19728
    role 19675
      application 19328
        pharmaceutical 19202
          drug 19202
            antineoplastic agent 16877
              mogrol 0
                mogroside IE 0
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  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    main group molecular entity 19610
                      s-block molecular entity 19378
                        hydrogen molecular entity 19367
                          hydrides 18278
                            organic hydride 17545
                              organic fundamental parent 17545
                                hydrocarbon 16957
                                  terpene 9326
                                    triterpene 640
                                      triterpenoid 636
                                        tetracyclic triterpenoid 229
                                          cucurbitadienol 0
                                            mogrol 0
                                              mogroside IE 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.