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ONTOLOGY REPORT - ANNOTATIONS


Term:carbocyclic thromboxane A2
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Accession:CHEBI:139043 term browser browse the term
Definition:A member of the class of thromboxanes that is thromboxane A2 in which the bridging oxygen has been replaced by a methylene group.
Synonyms:exact_synonym: (5Z)-7-{(1R,3R,4S,5R)-3-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[3.1.1]heptan-4-yl}hept-5-enoic acid
 related_synonym: 9alpha,11alpha-methylene thromboxane A2;   9alpha,11alpha-methylene-TXA2;   Formula=C21H34O4;   InChI=1S/C21H34O4/c1-2-3-6-9-17(22)12-13-20-19(16-14-18(15-16)25-20)10-7-4-5-8-11-21(23)24/h4,7,12-13,16-20,22H,2-3,5-6,8-11,14-15H2,1H3,(H,23,24)/b7-4-,13-12+/t16-,17-,18+,19-,20+/m0/s1;   InChIKey=VQUUFWNZZIMDBR-SXNJQZKASA-N;   SMILES=C1[C@H]2[C@@H]([C@H](O[C@@H]1C2)/C=C/[C@H](CCCCC)O)C/C=C\\CCCC(=O)O;   carbocyclic TXA2
 xref_mesh: MESH:C024587
 xref: PMID:10542977 "Europe PMC";   PMID:11483590 "Europe PMC";   PMID:12614148 "Europe PMC";   PMID:12628222 "Europe PMC";   PMID:1561230 "Europe PMC";   PMID:15789615 "Europe PMC";   PMID:16093422 "Europe PMC";   PMID:16896186 "Europe PMC";   PMID:17109692 "Europe PMC";   PMID:1838696 "Europe PMC";   PMID:3387452 "Europe PMC";   PMID:3512276 "Europe PMC";   PMID:6754126 "Europe PMC";   PMID:6960809 "Europe PMC";   PMID:7591017 "Europe PMC";   PMID:7693541 "Europe PMC";   PMID:7966472 "Europe PMC";   PMID:8135127 "Europe PMC";   PMID:8831114 "Europe PMC";   PMID:9014151 "Europe PMC";   PMID:9342927 "Europe PMC"
 cyclic_relationship: is_conjugate_acid_of CHEBI:138322


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carbocyclic thromboxane A2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TNFRSF11B TNF receptor superfamily member 11b JBrowse link 8 118,923,557 118,951,885 RGD:6480464
G TNFSF11 TNF superfamily member 11 JBrowse link 13 42,562,736 42,608,013 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 23805
    role 23692
      biological role 23655
        pharmacological role 20965
          agonist 18902
            thromboxane A2 agonist 2
              carbocyclic thromboxane A2 2
                18-hydroxycarbocyclic thromboxane A2 0
                19-hydroxycarbocyclic thromboxane A2 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 23805
    subatomic particle 23756
      composite particle 23756
        hadron 23756
          baryon 23756
            nucleon 23756
              atomic nucleus 23756
                atom 23756
                  main group element atom 23575
                    p-block element atom 23575
                      carbon group element atom 23289
                        carbon atom 23243
                          organic molecular entity 23243
                            organic group 21924
                              organic divalent group 21896
                                organodiyl group 21896
                                  carbonyl group 21868
                                    carbonyl compound 21868
                                      carboxylic acid 20917
                                        monocarboxylic acid 19815
                                          fatty acid 18119
                                            fatty acid derivative 1034
                                              icosanoid 458
                                                prostanoid 399
                                                  thromboxane 14
                                                    thromboxanes A 7
                                                      thromboxane A2 7
                                                        carbocyclic thromboxane A2 2
                                                          18-hydroxycarbocyclic thromboxane A2 0
                                                          19-hydroxycarbocyclic thromboxane A2 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.