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Term:19-hydroxycarbocyclic thromboxane A2
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Accession:CHEBI:139045 term browser browse the term
Definition:A member of the class of thromboxanes that is carbocyclic thromboxane A2 carrying an additional hydroxy substituent at position 19.
Synonyms:exact_synonym: (5Z)-7-{(1R,3R,4S,5R)-3-[(1E,3S)-3,7-dihydroxyoct-1-en-1-yl]-2-oxabicyclo[3.1.1]heptan-4-yl}hept-5-enoic acid
 related_synonym: 19-hydroxy-(9alpha,11alpha)-methylene thromboxane A2;   19-hydroxy-(9alpha,11alpha)-methylene-TXA2;   19-hydroxycarbocyclic TXA2;   Formula=C21H34O5;   InChI=1S/C21H34O5/c1-15(22)7-6-8-17(23)11-12-20-19(16-13-18(14-16)26-20)9-4-2-3-5-10-21(24)25/h2,4,11-12,15-20,22-23H,3,5-10,13-14H2,1H3,(H,24,25)/b4-2-,12-11+/t15?,16-,17-,18+,19-,20+/m0/s1;   InChIKey=RWKLFZNKJPQWRW-RBHGNWNXSA-N;   SMILES=C1[C@H]2[C@@H]([C@H](O[C@@H]1C2)/C=C/[C@H](CCCC(C)O)O)C/C=C\\CCCC(=O)O
 xref: PMID:15789615 "Europe PMC"
 cyclic_relationship: is_conjugate_acid_of CHEBI:138323

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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19734
    role 19680
      biological role 19678
        pharmacological role 18794
          agonist 18176
            thromboxane A2 agonist 2
              carbocyclic thromboxane A2 2
                19-hydroxycarbocyclic thromboxane A2 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19734
    subatomic particle 19730
      composite particle 19730
        hadron 19730
          baryon 19730
            nucleon 19730
              atomic nucleus 19730
                atom 19730
                  main group element atom 19614
                    p-block element atom 19614
                      carbon group element atom 19506
                        carbon atom 19500
                          organic molecular entity 19500
                            organic group 18414
                              organic divalent group 18406
                                organodiyl group 18406
                                  carbonyl group 18295
                                    carbonyl compound 18295
                                      carboxylic acid 17963
                                        monocarboxylic acid 17265
                                          fatty acid 15819
                                            fatty acid derivative 1018
                                              icosanoid 452
                                                prostanoid 395
                                                  thromboxane 14
                                                    thromboxanes A 7
                                                      thromboxane A2 7
                                                        carbocyclic thromboxane A2 2
                                                          19-hydroxycarbocyclic thromboxane A2 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.