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ONTOLOGY REPORT - ANNOTATIONS


Term:antalarmin
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Accession:CHEBI:139557 term browser browse the term
Definition:A pyrrolopyrimidine that is 7H-pyrrolo[2,3-d]pyrimidin-4-amine which is substituted by methyl groups at positions 2, 5, and 6, by a mesityl group at position 7, and in which the amino substituent at position 4 has been substituted by ethyl and butyl groups. It is an antagonist of corticotropin-releasing factor 1 (CRF-1) receptors (Ki = 1 nM).
Synonyms:exact_synonym: N-butyl-N-ethyl-7-mesityl-2,5,6-trimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
 related_synonym: Formula=C24H34N4;   InChI=1S/C24H34N4/c1-9-11-12-27(10-2)23-21-18(6)19(7)28(24(21)26-20(8)25-23)22-16(4)13-15(3)14-17(22)5/h13-14H,9-12H2,1-8H3;   InChIKey=IXPROWGEHNVJOY-UHFFFAOYSA-N;   SMILES=C12=C(N=C(N=C1N(C(=C2C)C)C=3C(=CC(=CC3C)C)C)C)N(CCCC)CC
 xref: CAS:157284-96-3 "ChemIDplus"
 xref_mesh: MESH:C103016
 xref: PMID:12097816 "Europe PMC";   PMID:15696320 "Europe PMC";   PMID:16820021 "Europe PMC";   PMID:17182090 "Europe PMC";   PMID:17397037 "Europe PMC";   PMID:17705061 "Europe PMC";   PMID:18423834 "Europe PMC";   PMID:18428980 "Europe PMC";   PMID:18830607 "Europe PMC";   PMID:19573565 "Europe PMC";   PMID:21203337 "Europe PMC";   PMID:23211705 "Europe PMC";   PMID:23796983 "Europe PMC";   PMID:24444675 "Europe PMC";   PMID:8940412 "Europe PMC";   PMID:9886810 "Europe PMC";   Wikipedia:Antalarmin


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antalarmin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Crhr1 corticotropin releasing hormone receptor 1 JBrowse link 10 92,191,473 92,233,662 RGD:6480464
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 JBrowse link 8 62,798,317 62,809,848 RGD:6480464
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 JBrowse link 1 266,422,127 266,429,947 RGD:6480464
G Faah fatty acid amide hydrolase JBrowse link 5 134,852,899 134,872,095 RGD:6480464
G Star steroidogenic acute regulatory protein JBrowse link 16 71,036,204 71,040,847 RGD:6480464
G Sult2a1 sulfotransferase family 2A member 1 JBrowse link 1 76,558,721 76,614,315 RGD:6480464

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Path 1
Term Annotations click to browse term
  CHEBI ontology 19749
    role 19696
      application 19347
        refrigerant 17097
          ammonia 16696
            organic amino compound 16695
              tertiary amino compound 8556
                antalarmin 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19749
    subatomic particle 19745
      composite particle 19745
        hadron 19745
          baryon 19745
            nucleon 19745
              atomic nucleus 19745
                atom 19745
                  main group element atom 19630
                    main group molecular entity 19630
                      s-block molecular entity 19390
                        hydrogen molecular entity 19379
                          hydrides 18296
                            inorganic hydride 17209
                              pnictogen hydride 17171
                                nitrogen hydride 17006
                                  azane 16699
                                    ammonia 16696
                                      organic amino compound 16695
                                        tertiary amino compound 8556
                                          antalarmin 6
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