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ONTOLOGY REPORT - ANNOTATIONS


Term:N-\{2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethyl\}-N-propylpropan-1-amine hydrochloride
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Accession:CHEBI:140905 term browser browse the term
Definition:An aromatic ether that is (2-phenoxyethyl)benzene which carries a 2-(dipropylamino)ethyl group at position 3 and a methoxy group at position 6. It is a potent and selective sigma1 receptor antagonist.
Synonyms:related_synonym: 4-methoxy-3-(2-phenylethoxy)-N,N-dipropyl-benzeneethanamine hydrochloride;   Formula=C23H34ClNO2;   InChI=1S/C23H33NO2.ClH/c1-4-15-24(16-5-2)17-13-21-11-12-22(25-3)23(19-21)26-18-14-20-9-7-6-8-10-20;/h6-12,19H,4-5,13-18H2,1-3H3;1H;   InChIKey=ZHGMDXSHODHWHV-UHFFFAOYSA-N;   N,N-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride;   N,N-dipropyl-2-[4-methoxy-3-(2-phenylethoxyl)phenyl]ethylamine hydrochloride;   NE-100;   SMILES=O(C=1C=C(CCN(CCC)CCC)C=CC1OC)CCC2=CC=CC=C2.[H]Cl
 xref: CAS:149409-57-4 "ChemIDplus";   CAS:149409-57-4 "SUBMITTER"
 xref_mesh: MESH:C083832
 xref: PMID:10090790 "SUBMITTER";   PMID:17556637 "Europe PMC";   PMID:27208832 "Europe PMC";   PMID:7475936 "Europe PMC";   PMID:7603628 "Europe PMC";   PMID:7609777 "Europe PMC";   PMID:7821367 "Europe PMC";   PMID:7823755 "Europe PMC";   PMID:7901723 "Europe PMC";   PMID:8041225 "Europe PMC";   PMID:8137864 "Europe PMC";   PMID:9544798 "Europe PMC";   Patent:EP0717990;   Patent:US5495046;   Reaxys:8296389 "Reaxys"


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N-\{2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethyl\}-N-propylpropan-1-amine hydrochloride term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sigmar1 sigma non-opioid intracellular receptor 1 JBrowse link 5 58,121,824 58,124,687 RGD:6480464

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Term Annotations click to browse term
  CHEBI ontology 19749
    role 19696
      application 19347
        pharmaceutical 19222
          drug 19222
            receptor modulator 18582
              N-\{2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethyl\}-N-propylpropan-1-amine hydrochloride 1
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Term Annotations click to browse term
  CHEBI ontology 19749
    subatomic particle 19745
      composite particle 19745
        hadron 19745
          baryon 19745
            nucleon 19745
              atomic nucleus 19745
                atom 19745
                  main group element atom 19630
                    main group molecular entity 19630
                      s-block molecular entity 19390
                        hydrogen molecular entity 19379
                          hydrides 18296
                            inorganic hydride 17209
                              pnictogen hydride 17171
                                nitrogen hydride 17006
                                  azane 16699
                                    ammonia 16696
                                      organic amino compound 16695
                                        tertiary amino compound 8556
                                          N-\{2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethyl\}-N-propylpropan-1-amine hydrochloride 1
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