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ONTOLOGY REPORT - ANNOTATIONS


Term:anagrelide
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Accession:CHEBI:142290 term browser browse the term
Definition:A 1,5-dihydroimidazo[2,1-]quinazoline having an oxo substituent at the 2-position and chloro substituents at the 6- and 7-positions.
Synonyms:exact_synonym: 6,7-dichloro-1,5-dihydroimidazo[2,1-]quinazolin-2(3H)-one
 related_synonym: Formula=C10H7Cl2N3O;   InChI=1S/C10H7Cl2N3O/c11-6-1-2-7-5(9(6)12)3-15-4-8(16)14-10(15)13-7/h1-2H,3-4H2,(H,13,14,16);   InChIKey=OTBXOEAOVRKTNQ-UHFFFAOYSA-N;   SMILES=Clc1ccc2N=C3NC(=O)CN3Cc2c1Cl;   anagrelida;   anagrelidum
 xref: Beilstein:619582 "Beilstein";   CAS:68475-42-3 "ChemIDplus";   CAS:68475-42-3 "DrugBank";   CAS:68475-42-3 "KEGG DRUG";   DrugBank:DB00261;   Drug_Central:209 "DrugCentral";   KEGG:D07455;   LINCS:LSM-3380
 xref_mesh: MESH:C021139
 xref: Wikipedia:Anagrelide


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anagrelide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fli1 Fli-1 proto-oncogene, ETS transcription factor JBrowse link 8 33,541,932 33,661,111 RGD:6480464
G Gata1 GATA binding protein 1 JBrowse link X 15,273,937 15,281,759 RGD:6480464
G Itga2b integrin subunit alpha 2b JBrowse link 10 90,397,960 90,416,550 RGD:6480464
G Mpl MPL proto-oncogene, thrombopoietin receptor JBrowse link 5 137,268,412 137,282,032 RGD:6480464
G Nfe2 nuclear factor, erythroid 2 JBrowse link 7 144,872,739 144,880,092 RGD:6480464
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:6480464
G Thpo thrombopoietin JBrowse link 11 82,845,676 82,853,439 RGD:6480464
G Zfpm1 zinc finger protein, multitype 1 JBrowse link 19 55,094,585 55,150,994 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      application 19308
        pharmaceutical 19179
          drug 19179
            cardiovascular drug 7568
              anagrelide 9
                anagrelide hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    p-block element atom 19598
                      carbon group element atom 19486
                        carbon atom 19480
                          organic molecular entity 19480
                            organic molecule 19402
                              organic cyclic compound 19158
                                organic heterocyclic compound 18245
                                  organic heteropolycyclic compound 17500
                                    organic heterotricyclic compound 13738
                                      imidazoquinazoline 9
                                        anagrelide 9
                                          anagrelide hydrochloride 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.