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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:organometalloidal compound
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Accession:CHEBI:143084 term browser browse the term
Definition:A compound having bonds between one or more metalloid atoms and one or more carbon atoms of an organyl group.
Synonyms:related_synonym: organometalloidal;   organometalloidal compounds;   organometalloidals
 xref: PMID:15246002;   PMID:17741021;   PMID:8403081;   PMID:908316


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arsanilic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases activity EXP Arsanilic Acid results in increased activity of CASP3 protein CTD PMID:23848144 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 increases activity EXP Arsanilic Acid results in increased activity of CASP9 protein CTD PMID:23848144 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
dimethylarsinic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression
decreases expression
EXP Cacodylic Acid results in increased expression of ABCB1A mRNA; Cacodylic Acid results in increased expression of ABCB1A protein
Cacodylic Acid results in decreased expression of ABCB1A mRNA
CTD PMID:16436460, PMID:17720352 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression
affects transport
decreases response to substance
increases transport
EXP
ISO
Cacodylic Acid results in increased expression of ABCC1 mRNA; Cacodylic Acid results in increased expression of ABCC1 protein
ABCC1 protein modified form affects the transport of Cacodylic Acid
ABCC1 protein results in decreased susceptibility to Cacodylic Acid
ABCC1 protein results in increased transport of Cacodylic Acid
CTD PMID:16436460, PMID:29752257 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression EXP Cacodylic Acid results in increased expression of ABCC2 mRNA; Cacodylic Acid results in increased expression of ABCC2 protein CTD PMID:16436460 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression EXP Cacodylic Acid results in increased expression of ABCC3 mRNA; Cacodylic Acid results in increased expression of ABCC3 protein CTD PMID:16436460 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases transport
affects export
increases export
ISO ABCC4 protein results in increased transport of Cacodylic Acid
ABCC4 gene SNP affects the export of Cacodylic Acid
ABCC4 protein results in increased export of Cacodylic Acid
CTD PMID:24870404, PMID:25752797, PMID:27659809 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Ache acetylcholinesterase decreases activity ISO Cacodylic Acid results in decreased activity of ACHE protein CTD PMID:21440049 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Actn1 actinin, alpha 1 increases expression EXP Cacodylic Acid results in increased expression of ACTN1 mRNA CTD PMID:17720352 NCBI chr 6:103,376,557...103,470,497
Ensembl chr 6:103,375,799...103,470,555
JBrowse link
G Adm adrenomedullin increases expression ISO Cacodylic Acid results in increased expression of ADM mRNA CTD PMID:32052077 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Afp alpha-fetoprotein increases expression ISO Cacodylic Acid results in increased expression of AFP mRNA CTD PMID:15345372 NCBI chr14:19,141,755...19,159,919
Ensembl chr14:19,141,755...19,159,923
JBrowse link
G Agtrap angiotensin II receptor-associated protein decreases expression ISO Cacodylic Acid results in decreased expression of AGTRAP mRNA CTD PMID:22246474 NCBI chr 5:164,888,069...164,898,387
Ensembl chr 5:164,886,813...164,898,420
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO AHR mutant form inhibits the reaction [Cacodylic Acid results in increased expression of CYP1A1 protein]; Cacodylic Acid results in decreased expression of and affects the localization of AHR protein
Cacodylic Acid affects the reaction [[Tetrachlorodibenzodioxin results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; Cacodylic Acid affects the reaction [[Tetrachlorodibenzodioxin results in increased activity of AHR protein] which results in increased expression of CYP1A1 protein]
CTD PMID:24161444, PMID:28134025 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ahsg alpha-2-HS-glycoprotein decreases expression ISO Cacodylic Acid results in decreased expression of AHSG mRNA CTD PMID:32052077 NCBI chr11:81,711,269...81,717,594 JBrowse link
G Aire autoimmune regulator multiple interactions ISO [Arsenic results in increased abundance of Cacodylic Acid] which affects the expression of AIRE mRNA CTD PMID:28793237 NCBI chr20:11,365,630...11,380,636
Ensembl chr20:11,365,697...11,380,631
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of AKT1 mRNA CTD PMID:23192986 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alb albumin decreases expression ISO Cacodylic Acid results in decreased expression of ALB mRNA CTD PMID:32052077 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aoc3 amine oxidase, copper containing 3 multiple interactions
increases expression
ISO OGG1 protein inhibits the reaction [Cacodylic Acid results in increased expression of AOC3 mRNA] CTD PMID:17441966 NCBI chr10:89,251,370...89,259,313
Ensembl chr10:89,251,370...89,259,313
JBrowse link
G Apoe apolipoprotein E affects response to substance
multiple interactions
ISO APOE protein affects the susceptibility to Cacodylic Acid
AS3MT protein affects the reaction [APOE protein affects the susceptibility to Cacodylic Acid]
CTD PMID:28728140 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G App amyloid beta precursor protein multiple interactions
increases expression
ISO Cacodylic Acid results in increased cleavage of and affects the secretion of APP protein mutant form; Cacodylic Acid results in increased expression of and affects the localization of APP protein mutant form
Cacodylic Acid results in increased expression of APP protein
CTD PMID:21440049 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Aqp7 aquaporin 7 increases expression EXP Cacodylic Acid results in increased expression of AQP7 mRNA CTD PMID:17720352 NCBI chr 5:57,358,297...57,372,332
Ensembl chr 5:57,358,327...57,372,239
JBrowse link
G Arf6 ADP-ribosylation factor 6 increases expression EXP Cacodylic Acid results in increased expression of ARF6 mRNA CTD PMID:16122865 NCBI chr 6:91,697,109...91,698,257
Ensembl chr 6:91,697,109...91,698,255
JBrowse link
G Arhgap21 Rho GTPase activating protein 21 increases expression ISO Cacodylic Acid results in increased expression of ARHGAP21 mRNA CTD PMID:17720352 NCBI chr17:87,725,978...87,797,436
Ensembl chr17:87,725,867...87,826,421
JBrowse link
G As3mt arsenite methyltransferase multiple interactions ISO [AS3MT gene polymorphism affects the susceptibility to Arsenic] which results in increased abundance of Cacodylic Acid; [AS3MT protein polymorphism results in increased metabolism of arsenite] which results in increased chemical synthesis of Cacodylic Acid; [AS3MT protein polymorphism results in increased metabolism of monomethylarsonic acid] which results in increased chemical synthesis of Cacodylic Acid; [AS3MT protein results in increased metabolism of arsenite] which results in increased chemical synthesis of Cacodylic Acid; [AS3MT protein results in increased metabolism of monomethylarsonic acid] which results in increased chemical synthesis of Cacodylic Acid
AS3MT protein affects the reaction [APOE protein affects the susceptibility to Cacodylic Acid]
CTD PMID:22868225, PMID:24845704, PMID:28728140 NCBI chr 1:266,482,787...266,514,570
Ensembl chr 1:266,482,858...266,514,569
JBrowse link
G Atf4 activating transcription factor 4 increases expression EXP
ISO
Cacodylic Acid results in increased expression of ATF4 mRNA CTD PMID:16122865, PMID:23221991 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atp6v0a4 ATPase H+ transporting V0 subunit a4 increases expression ISO Cacodylic Acid results in increased expression of ATP6V0A4 mRNA CTD PMID:32052077 NCBI chr 4:65,736,585...65,821,916
Ensembl chr 4:65,736,585...65,818,521
JBrowse link
G Bad BCL2-associated agonist of cell death increases expression EXP
ISO
Cacodylic Acid results in increased expression of BAD mRNA
Cacodylic Acid results in increased expression of BAD mRNA; Cacodylic Acid results in increased expression of BAD protein
CTD PMID:16122865, PMID:22246474 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP Cacodylic Acid results in increased expression of BAX mRNA CTD PMID:16122865 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase decreases expression EXP Cacodylic Acid results in decreased expression of BCKDK mRNA CTD PMID:16122865 NCBI chr 1:199,351,628...199,356,299
Ensembl chr 1:199,351,628...199,356,881
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression ISO Cacodylic Acid results in increased expression of BCL2 mRNA; Cacodylic Acid results in increased expression of BCL2 protein CTD PMID:22246474 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression ISO Cacodylic Acid results in increased expression of BCL2L1 mRNA CTD PMID:17720352 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bex3 brain expressed X-linked 3 increases expression EXP Cacodylic Acid results in increased expression of BEX3 mRNA CTD PMID:16122865 NCBI chr  X:106,823,442...106,825,016
Ensembl chr  X:106,823,491...106,825,014
JBrowse link
G Bmp1 bone morphogenetic protein 1 decreases expression ISO Cacodylic Acid results in decreased expression of BMP1 mRNA CTD PMID:17720352 NCBI chr15:52,166,401...52,210,786
Ensembl chr15:52,166,401...52,210,746
JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A increases expression EXP Cacodylic Acid results in increased expression of BMPR1A mRNA CTD PMID:17720352 NCBI chr16:10,758,278...10,852,170
Ensembl chr16:10,758,527...10,802,512
JBrowse link
G Bok BCL2 family apoptosis regulator BOK increases expression EXP Cacodylic Acid results in increased expression of BOK mRNA CTD PMID:16122865 NCBI chr 9:100,829,593...100,840,498
Ensembl chr 9:100,829,552...100,840,504
JBrowse link
G C7 complement C7 multiple interactions ISO [Arsenic results in increased abundance of Cacodylic Acid] which affects the expression of C7 mRNA CTD PMID:28793237 NCBI chr 2:54,707,621...54,781,624
Ensembl chr 2:54,709,138...54,777,729
JBrowse link
G C9 complement C9 multiple interactions ISO [Arsenic results in increased abundance of Cacodylic Acid] which affects the expression of C9 mRNA CTD PMID:28793237 NCBI chr 2:55,775,562...55,823,807
Ensembl chr 2:55,775,274...55,823,826
JBrowse link
G Ca12 carbonic anhydrase 12 increases expression ISO Cacodylic Acid results in increased expression of CA12 mRNA CTD PMID:17720352 NCBI chr 8:72,405,770...72,461,425
Ensembl chr 8:72,405,748...72,460,240
JBrowse link
G Ca13 carbonic anhydrase 13 increases expression ISO Cacodylic Acid results in increased expression of CAR13 mRNA CTD PMID:17441966 NCBI chr 2:88,282,961...88,314,254
Ensembl chr 2:88,282,961...88,314,254
JBrowse link
G Ca3 carbonic anhydrase 3 decreases expression ISO Cacodylic Acid results in decreased expression of CAR3 mRNA CTD PMID:17441966 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410
JBrowse link
G Calm2 calmodulin 2 increases expression EXP Cacodylic Acid results in increased expression of CALM2 mRNA CTD PMID:16122865 NCBI chr 6:11,067,675...11,080,078
Ensembl chr15:65,506,874...65,507,968
JBrowse link
G Calu calumenin increases expression EXP Cacodylic Acid results in increased expression of CALU mRNA CTD PMID:16122865 NCBI chr 4:56,625,611...56,653,112
Ensembl chr 4:56,625,561...56,653,111
JBrowse link
G Cap1 cyclase associated actin cytoskeleton regulatory protein 1 increases expression EXP Cacodylic Acid results in increased expression of CAP1 mRNA CTD PMID:16122865 NCBI chr 5:140,559,195...140,585,494
Ensembl chr 5:140,559,206...140,585,408
JBrowse link
G Capn9 calpain 9 increases expression EXP Cacodylic Acid results in increased expression of CAPN9 mRNA CTD PMID:17720352 NCBI chr19:57,341,938...57,378,901
Ensembl chr19:57,341,938...57,378,901
JBrowse link
G Casp12 caspase 12 increases expression ISO Cacodylic Acid results in increased expression of CASP12 mRNA; Cacodylic Acid results in increased expression of CASP12 protein CTD PMID:22246474 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp2 caspase 2 increases expression ISO Cacodylic Acid analog results in increased expression of CASP2 protein CTD PMID:23994116 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases expression
increases response to substance
EXP
ISO
benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [CASP3 protein results in increased susceptibility to Cacodylic Acid]; Buthionine Sulfoximine inhibits the reaction [Cacodylic Acid results in increased activity of CASP3 protein]
[sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of CASP3 mRNA
Cacodylic Acid analog results in increased activity of CASP3 protein; Cacodylic Acid results in increased activity of CASP3 protein
Cacodylic Acid results in increased expression of CASP3 mRNA
CTD PMID:15276415, PMID:16122865, PMID:19465042, PMID:23192986, PMID:23994116 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp6 caspase 6 affects binding ISO CASP6 protein binds to Cacodylic Acid analog CTD PMID:21912678 NCBI chr 2:235,341,326...235,353,715
Ensembl chr 2:235,341,365...235,353,967
Ensembl chr 2:235,341,365...235,353,967
JBrowse link
G Casp8 caspase 8 multiple interactions
increases response to substance
EXP benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [CASP8 protein results in increased susceptibility to Cacodylic Acid] CTD PMID:15276415 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions
increases response to substance
EXP benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [CASP9 protein results in increased susceptibility to Cacodylic Acid] CTD PMID:15276415 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase increases expression
decreases activity
multiple interactions
EXP Cacodylic Acid results in increased expression of CAT mRNA
Cacodylic Acid results in decreased activity of CAT protein
[CAT protein results in decreased oxidation of dimethylarsinous acid] which results in decreased chemical synthesis of Cacodylic Acid
CTD PMID:16122865, PMID:18619986, PMID:24095718 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav2 caveolin 2 decreases expression ISO Cacodylic Acid results in decreased expression of CAV2 mRNA CTD PMID:17720352 NCBI chr 4:44,573,264...44,580,640
Ensembl chr 4:44,573,264...44,580,638
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 decreases expression ISO Cacodylic Acid results in decreased expression of CCL11 mRNA CTD PMID:32052077 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
JBrowse link
G Ccl26 C-C motif chemokine ligand 26 multiple interactions ISO [Arsenic results in increased abundance of Cacodylic Acid] which affects the expression of CCL26 mRNA CTD PMID:28793237 NCBI chr12:24,157,182...24,161,870
Ensembl chr12:24,158,766...24,161,869
JBrowse link
G Ccnc cyclin C increases expression
multiple interactions
ISO Cacodylic Acid results in increased expression of CCNC mRNA
OGG1 protein inhibits the reaction [Cacodylic Acid results in increased expression of CCNC mRNA]
CTD PMID:17441966 NCBI chr 5:35,865,598...35,883,732
Ensembl chr 5:35,865,605...35,883,706
JBrowse link
G Ccnd1 cyclin D1 increases expression EXP Cacodylic Acid results in increased expression of CCND1 mRNA; Cacodylic Acid results in increased expression of CCND1 protein CTD PMID:12151359, PMID:17481689, PMID:24832369 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd2 cyclin D2 affects expression EXP Cacodylic Acid affects the expression of CCND2 mRNA CTD PMID:17720352 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Cd2 Cd2 molecule increases expression EXP Cacodylic Acid results in increased expression of CD2 mRNA CTD PMID:16122865 NCBI chr 2:203,666,706...203,680,073
Ensembl chr 2:203,666,637...203,680,083
JBrowse link
G Cd36 CD36 molecule decreases expression ISO Cacodylic Acid results in decreased expression of CD36 mRNA CTD PMID:23221991 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd68 Cd68 molecule increases expression ISO Cacodylic Acid results in increased expression of CD68 mRNA CTD PMID:17720352 NCBI chr10:56,268,726...56,270,605
Ensembl chr10:56,268,720...56,270,640
JBrowse link
G Cdc123 cell division cycle 123 increases expression EXP Cacodylic Acid results in increased expression of CDC123 mRNA CTD PMID:16122865 NCBI chr17:76,410,629...76,454,275
Ensembl chr17:76,410,585...76,454,282
JBrowse link
G Cdc37 cell division cycle 37, HSP90 cochaperone increases expression EXP Cacodylic Acid results in increased expression of CDC37 mRNA CTD PMID:16122865 NCBI chr 8:22,160,922...22,173,797
Ensembl chr 8:22,154,067...22,173,804
JBrowse link
G Cdc5l cell division cycle 5-like increases expression EXP Cacodylic Acid results in increased expression of CDC5L mRNA CTD PMID:16122865 NCBI chr 9:17,949,764...17,988,514
Ensembl chr 9:17,949,764...17,988,509
JBrowse link
G Cdh1 cadherin 1 increases expression EXP Cacodylic Acid results in increased expression of CDH1 mRNA CTD PMID:16122865, PMID:17481689 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdh13 cadherin 13 affects expression EXP Cacodylic Acid affects the expression of CDH13 mRNA CTD PMID:17720352 NCBI chr19:50,848,793...51,971,618
Ensembl chr19:50,848,736...51,972,103
JBrowse link
G Cdh4 cadherin 4 increases expression
multiple interactions
ISO Cacodylic Acid results in increased expression of CDH4 mRNA
OGG1 protein inhibits the reaction [Cacodylic Acid results in increased expression of CDH4 mRNA]
CTD PMID:17441966 NCBI chr 3:175,220,520...175,283,144
Ensembl chr 3:175,144,495...175,279,761
JBrowse link
G Cdh8 cadherin 8 decreases expression EXP Cacodylic Acid results in decreased expression of CDH8 mRNA CTD PMID:16122865 NCBI chr19:6,031,654...6,431,502
Ensembl chr19:6,046,665...6,426,216
JBrowse link
G Cdk9 cyclin-dependent kinase 9 increases expression EXP Cacodylic Acid results in increased expression of CDK9 mRNA CTD PMID:17720352 NCBI chr 3:11,742,269...11,747,117
Ensembl chr 3:11,742,266...11,747,113
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression
multiple interactions
EXP
ISO
Cacodylic Acid results in decreased expression of CDKN1A mRNA; Cacodylic Acid results in decreased expression of CDKN1A protein
[sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of CDKN1A mRNA
CTD PMID:12151359, PMID:17481689, PMID:23192986 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A decreases expression
decreases methylation
EXP
ISO
Cacodylic Acid results in decreased expression of CDKN2A mRNA
Cacodylic Acid results in decreased methylation of CDKN2A promoter alternative form
CTD PMID:16122865, PMID:23073540 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B decreases expression EXP Cacodylic Acid results in decreased expression of CDKN2B mRNA CTD PMID:17720352 NCBI chr 5:107,834,353...107,857,428
Ensembl chr 5:107,845,951...107,858,104
JBrowse link
G Ceacam6 CEA cell adhesion molecule 6 multiple interactions ISO [Arsenic results in increased abundance of Cacodylic Acid] which affects the expression of CEACAM6 mRNA CTD PMID:28793237 NCBI chr 1:81,683,500...81,701,230
Ensembl chr 1:81,683,463...81,701,317
JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma decreases expression EXP Cacodylic Acid results in decreased expression of CEBPG mRNA CTD PMID:17720352 NCBI chr 1:91,286,956...91,297,459
Ensembl chr 1:91,287,917...91,296,656
JBrowse link
G Celsr3 cadherin, EGF LAG seven-pass G-type receptor 3 decreases expression EXP Cacodylic Acid results in decreased expression of CELSR3 mRNA CTD PMID:16122865 NCBI chr 8:117,620,293...117,648,034
Ensembl chr 8:117,620,317...117,648,028
JBrowse link
G Cemip cell migration inducing hyaluronidase increases expression ISO Cacodylic Acid results in increased expression of CEMIP mRNA CTD PMID:32052077 NCBI chr 1:146,069,774...146,226,320
Ensembl chr 1:146,069,771...146,226,462
JBrowse link
G Cfd complement factor D increases expression
multiple interactions
ISO Cacodylic Acid results in increased expression of CFD mRNA
OGG1 protein inhibits the reaction [Cacodylic Acid results in increased expression of CFD mRNA]
CTD PMID:17441966 NCBI chr 7:12,634,216...12,635,939
Ensembl chr 7:12,634,216...12,635,943
JBrowse link
G Chat choline O-acetyltransferase increases activity ISO Cacodylic Acid results in increased activity of CHAT protein CTD PMID:21440049 NCBI chr16:8,576,858...8,686,131
Ensembl chr16:8,577,840...8,686,131
JBrowse link
G Chek2 checkpoint kinase 2 increases expression EXP Cacodylic Acid results in increased expression of CHEK2 mRNA CTD PMID:17720352 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Chi3l1 chitinase 3 like 1 increases expression ISO Cacodylic Acid results in increased expression of CHIL1 mRNA CTD PMID:32052077 NCBI chr13:51,022,844...51,030,797
Ensembl chr13:51,022,681...51,030,802
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex increases expression EXP Cacodylic Acid results in increased expression of CHUK mRNA; Cacodylic Acid results in increased expression of CHUK protein CTD PMID:26617437 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169
JBrowse link
G Col7a1 collagen type VII alpha 1 chain decreases expression ISO Cacodylic Acid results in decreased expression of COL7A1 mRNA CTD PMID:17441966 NCBI chr 8:117,694,441...117,726,844
Ensembl chr 8:117,694,605...117,726,844
JBrowse link
G Comp cartilage oligomeric matrix protein increases expression EXP Cacodylic Acid results in increased expression of COMP mRNA CTD PMID:16122865 NCBI chr16:20,798,437...20,807,070
Ensembl chr16:20,798,437...20,807,070
JBrowse link
G Cpd carboxypeptidase D decreases expression EXP Cacodylic Acid results in decreased expression of CPD mRNA CTD PMID:17720352 NCBI chr10:63,325,764...63,389,811
Ensembl chr10:63,325,199...63,389,817
JBrowse link
G Ctnnd2 catenin delta 2 increases expression ISO Cacodylic Acid results in increased expression of CTNND2 mRNA CTD PMID:17441966 NCBI chr 2:83,227,247...84,094,315
Ensembl chr 2:83,393,282...84,094,315
JBrowse link
G Ctsg cathepsin G multiple interactions ISO [Arsenic results in increased abundance of Cacodylic Acid] which affects the expression of CTSG mRNA CTD PMID:28793237 NCBI chr15:35,107,333...35,113,678
Ensembl chr15:35,111,091...35,113,678
JBrowse link
G Cxcl17 C-X-C motif chemokine ligand 17 decreases expression ISO Cacodylic Acid results in decreased expression of CXCL17 mRNA CTD PMID:32052077 NCBI chr 1:82,267,381...82,279,145
Ensembl chr 1:82,267,381...82,279,145
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO AHR mutant form inhibits the reaction [Cacodylic Acid results in increased expression of CYP1A1 protein]; Cacodylic Acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A1 protein]; Cacodylic Acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Cacodylic Acid results in increased expression of and results in increased activity of CYP1A1 protein
Cacodylic Acid affects the reaction [[Tetrachlorodibenzodioxin results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; Cacodylic Acid affects the reaction [[Tetrachlorodibenzodioxin results in increased activity of AHR protein] which results in increased expression of CYP1A1 protein]
Cacodylic Acid results in increased expression of CYP1A1 mRNA
CTD PMID:24161444, PMID:28134025 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP Cacodylic Acid results in increased expression of CYP1A2 mRNA CTD PMID:17481689 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions
increases expression
EXP [Cacodylic Acid co-treated with Diethylnitrosamine] results in increased expression of CYP2B1 mRNA; [Cacodylic Acid co-treated with Diethylnitrosamine] results in increased expression of CYP2B1 protein
Cacodylic Acid results in increased expression of CYP2B1 mRNA
CTD PMID:12115560, PMID:17481689 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 multiple interactions EXP [Cacodylic Acid co-treated with Diethylnitrosamine] results in increased expression of CYP2B2 mRNA CTD PMID:12115560 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP Cacodylic Acid results in increased expression of CYP3A23-3A1 mRNA CTD PMID:17481689 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 increases expression
multiple interactions
ISO Cacodylic Acid results in increased expression of CYP7B1 mRNA
OGG1 protein inhibits the reaction [Cacodylic Acid results in increased expression of CYP7B1 mRNA]
CTD PMID:17441966 NCBI chr 2:102,701,903...102,871,257
Ensembl chr 2:102,701,903...102,871,257
JBrowse link
G Ddb2 damage specific DNA binding protein 2 multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of DDB2 mRNA CTD PMID:23192986 NCBI chr 3:80,030,437...80,052,984
Ensembl chr 3:80,030,437...80,052,953
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Cacodylic Acid results in increased expression of DDIT3 mRNA CTD PMID:23221991 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddx3y DEAD-box helicase 3, Y-linked increases expression ISO Cacodylic Acid results in increased expression of DDX3Y mRNA CTD PMID:22246474 NCBI chr13:105,408,179...105,411,348
Ensembl chr13:105,408,179...105,411,348
JBrowse link
G Dgkb diacylglycerol kinase, beta decreases expression ISO Cacodylic Acid results in decreased expression of DGKB mRNA CTD PMID:32052077 NCBI chr 6:57,516,351...58,277,385
Ensembl chr 6:57,516,713...58,277,279
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 decreases expression EXP Cacodylic Acid results in decreased expression of EEF1A1 mRNA CTD PMID:17720352 NCBI chr 8:85,838,594...85,841,816
Ensembl chr 8:85,838,869...85,840,818
JBrowse link
G Egfr epidermal growth factor receptor increases expression EXP Cacodylic Acid results in increased expression of EGFR mRNA CTD PMID:16122865 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egr1 early growth response 1 increases expression
multiple interactions
ISO Cacodylic Acid results in increased expression of EGR1 mRNA
[Arsenic results in increased abundance of Cacodylic Acid] which affects the expression of EGR1 mRNA; [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of EGR1 mRNA
CTD PMID:15345372, PMID:23192986, PMID:28793237 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Ehd3 EH-domain containing 3 increases expression ISO Cacodylic Acid results in increased expression of EHD3 mRNA CTD PMID:32052077 NCBI chr 6:25,076,012...25,102,457
Ensembl chr 6:25,074,955...25,100,977
JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 increases expression ISO Cacodylic Acid results in increased expression of EHMT2 mRNA CTD PMID:32052077 NCBI chr20:4,576,033...4,592,980
Ensembl chr20:4,576,057...4,592,980
JBrowse link
G Emb embigin increases expression EXP Cacodylic Acid results in increased expression of EMB mRNA CTD PMID:16122865 NCBI chr 2:49,682,763...49,733,475
Ensembl chr 2:49,682,754...49,732,253
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of ESR1 mRNA CTD PMID:23192986 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Fas Fas cell surface death receptor decreases expression ISO Cacodylic Acid results in decreased expression of FAS mRNA CTD PMID:29864498 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand increases expression
decreases expression
EXP
ISO
Cacodylic Acid results in increased expression of FASLG mRNA
Cacodylic Acid results in decreased expression of FASL mRNA
CTD PMID:15345372, PMID:17481689 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fev FEV transcription factor, ETS family member decreases expression EXP Cacodylic Acid results in decreased expression of FEV mRNA CTD PMID:16122865 NCBI chr 9:82,142,981...82,146,855
Ensembl chr 9:82,142,981...82,146,874
JBrowse link
G Fgf2 fibroblast growth factor 2 increases expression ISO Cacodylic Acid results in increased expression of FGF2 mRNA CTD PMID:15345372 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fgf23 fibroblast growth factor 23 decreases expression ISO Cacodylic Acid results in decreased expression of FGF23 mRNA CTD PMID:17441966 NCBI chr 4:159,622,404...159,630,082
Ensembl chr 4:159,622,404...159,630,082
JBrowse link
G Fgf9 fibroblast growth factor 9 increases expression EXP Cacodylic Acid results in increased expression of FGF9 mRNA CTD PMID:17720352 NCBI chr15:38,341,657...38,386,945
Ensembl chr15:38,341,089...38,387,316
JBrowse link
G Fibcd1 fibrinogen C domain containing 1 decreases expression ISO Cacodylic Acid results in decreased expression of FIBCD1 mRNA CTD PMID:22246474 NCBI chr 3:9,365,866...9,399,578
Ensembl chr 3:9,366,053...9,396,450
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of FKBP5 mRNA CTD PMID:23192986 NCBI chr20:7,976,704...8,097,290
Ensembl chr20:7,976,713...8,019,020
JBrowse link
G Flg filaggrin increases expression ISO Cacodylic Acid results in increased expression of FLG mRNA CTD PMID:32052077 NCBI chr 2:193,565,401...193,574,297 JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of FOS mRNA CTD PMID:23192986 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Foxq1 forkhead box Q1 increases expression EXP Cacodylic Acid results in increased expression of FOXQ1 mRNA CTD PMID:16122865 NCBI chr17:34,224,308...34,226,941
Ensembl chr17:34,224,818...34,226,453
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression EXP Cacodylic Acid results in increased expression of FTH1 mRNA CTD PMID:16122865 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Ftl1 ferritin light chain 1 increases expression EXP Cacodylic Acid results in increased expression of FTL1 mRNA CTD PMID:16122865 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G Fut11 fucosyltransferase 11 decreases expression ISO Cacodylic Acid results in decreased expression of FUT11 mRNA CTD PMID:22246474 NCBI chr15:4,031,504...4,035,064
Ensembl chr15:4,031,504...4,035,064
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression EXP
ISO
Cacodylic Acid results in increased expression of GADD45A mRNA
Cacodylic Acid analog results in increased expression of GADD45A protein
CTD PMID:16122865, PMID:23994116 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gak cyclin G associated kinase increases expression EXP Cacodylic Acid results in increased expression of GAK mRNA CTD PMID:16122865 NCBI chr14:2,100,104...2,174,332
Ensembl chr14:2,100,106...2,174,318
JBrowse link
G Gdi2 GDP dissociation inhibitor 2 increases expression EXP Cacodylic Acid results in increased expression of GDI2 mRNA CTD PMID:16122865 NCBI chr17:70,299,177...70,325,864
Ensembl chr17:70,299,183...70,325,855
JBrowse link
G Gjb1 gap junction protein, beta 1 increases expression EXP Cacodylic Acid results in increased expression of GJB1 mRNA CTD PMID:17481689 NCBI chr  X:71,272,030...71,279,973
Ensembl chr  X:71,272,042...71,279,977
JBrowse link
G Gjb4 gap junction protein, beta 4 increases expression ISO Cacodylic Acid results in increased expression of GJB4 mRNA CTD PMID:32052077 NCBI chr 5:145,416,343...145,421,122
Ensembl chr 5:145,416,343...145,418,992
JBrowse link
G Glrx glutaredoxin increases expression EXP Cacodylic Acid results in increased expression of GLRX mRNA CTD PMID:17720352 NCBI chr 2:2,606,032...2,615,944
Ensembl chr 2:2,605,996...2,615,944
JBrowse link
G Gls2 glutaminase 2 increases expression ISO Cacodylic Acid results in increased expression of GLS2 mRNA CTD PMID:17720352 NCBI chr 7:2,605,679...2,621,853
Ensembl chr 7:2,605,719...2,621,852
JBrowse link
G Gng5 G protein subunit gamma 5 increases expression ISO Cacodylic Acid results in increased expression of GNG5 mRNA CTD PMID:17441966 NCBI chr 2:252,359,976...252,368,473
Ensembl chr 2:252,359,976...252,368,473
JBrowse link
G Gp1bb glycoprotein Ib platelet subunit beta multiple interactions ISO [Arsenic results in increased abundance of Cacodylic Acid] which affects the expression of GP1BB mRNA CTD PMID:28793237 NCBI chr11:86,520,992...86,522,169
Ensembl chr11:86,520,992...86,522,169
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression EXP Cacodylic Acid results in increased expression of GPX1 mRNA CTD PMID:16122865 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Grn granulin precursor increases expression EXP Cacodylic Acid results in increased expression of GRN mRNA CTD PMID:16122865 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
G Grpel1 GrpE-like 1, mitochondrial increases expression EXP Cacodylic Acid results in increased expression of GRPEL1 mRNA CTD PMID:16122865 NCBI chr14:79,458,951...79,464,782
Ensembl chr14:79,458,963...79,464,770
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 decreases expression
increases expression
EXP Cacodylic Acid results in decreased expression of GSTA2 mRNA; Cacodylic Acid results in decreased expression of GSTA2 protein
Cacodylic Acid results in increased expression of GSTA2 mRNA
CTD PMID:16436460, PMID:17481689 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gsta4 glutathione S-transferase alpha 4 increases expression ISO Cacodylic Acid results in increased expression of GSTA4 mRNA CTD PMID:17720352 NCBI chr 8:85,497,557...85,514,732
Ensembl chr 8:85,497,557...85,518,879
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP
ISO
Cacodylic Acid results in increased expression of GSTM1 mRNA; Cacodylic Acid results in increased expression of GSTM1 protein
Cacodylic Acid results in increased expression of GSTM5 mRNA
CTD PMID:15345372, PMID:16436460 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression
decreases expression
EXP
ISO
Cacodylic Acid results in increased expression of GSTP1 mRNA
Cacodylic Acid results in decreased expression of GSTP1 mRNA
CTD PMID:16122865, PMID:17481689, PMID:32052077 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gstt1 glutathione S-transferase theta 1 affects metabolic processing
affects response to substance
ISO GSTT1 protein affects the metabolism of Cacodylic Acid
GSTT1 gene affects the susceptibility to Cacodylic Acid
CTD PMID:17431481 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Gtf2f2 general transcription factor IIF subunit 2 increases expression EXP Cacodylic Acid results in increased expression of GTF2F2 mRNA CTD PMID:16122865 NCBI chr15:57,942,057...58,068,892
Ensembl chr15:57,942,059...58,068,892
JBrowse link
G H1f0 H1 histone family, member 0 increases expression EXP Cacodylic Acid results in increased expression of H1F0 mRNA CTD PMID:16122865 NCBI chr 7:120,260,776...120,262,636 JBrowse link
G Hapln2 hyaluronan and proteoglycan link protein 2 decreases expression EXP Cacodylic Acid results in decreased expression of HAPLN2 mRNA CTD PMID:16122865 NCBI chr 2:187,395,104...187,402,076
Ensembl chr 2:187,396,349...187,401,786
JBrowse link
G Higd2a HIG1 hypoxia inducible domain family, member 2A decreases expression ISO Cacodylic Acid results in decreased expression of HIGD2A mRNA CTD PMID:32052077 NCBI chr17:10,558,714...10,559,638
Ensembl chr17:10,558,714...10,559,627
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO Cacodylic Acid results in increased expression of HMOX1 mRNA
[sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of HMOX1 mRNA
CTD PMID:15345372, PMID:23192986 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hoxa1 homeobox A1 decreases expression EXP Cacodylic Acid results in decreased expression of HOXA1 mRNA CTD PMID:16122865 NCBI chr 4:82,124,358...82,127,182
Ensembl chr 4:82,125,406...82,127,066
JBrowse link
G Hoxa2 homeobox A2 decreases expression EXP Cacodylic Acid results in decreased expression of HOXA2 mRNA CTD PMID:16122865 NCBI chr 4:82,130,441...82,134,846
Ensembl chr 4:82,131,329...82,133,605
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B multiple interactions
decreases expression
ISO OGG1 protein inhibits the reaction [Cacodylic Acid results in decreased expression of HSPA1B mRNA] CTD PMID:17441966 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Hspa4l heat shock protein family A (Hsp70) member 4 like multiple interactions
decreases expression
ISO OGG1 protein inhibits the reaction [Cacodylic Acid results in decreased expression of HSPA4L mRNA] CTD PMID:17441966 NCBI chr 2:127,625,737...127,682,864
Ensembl chr 2:127,625,683...127,677,503
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression EXP Cacodylic Acid results in increased expression of HSPA5 mRNA CTD PMID:16122865 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression
multiple interactions
ISO Cacodylic Acid results in decreased expression of HSPA8 mRNA
OGG1 protein inhibits the reaction [Cacodylic Acid results in decreased expression of HSPA8 mRNA]
CTD PMID:17441966 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 decreases expression
multiple interactions
ISO Cacodylic Acid results in decreased expression of HSPB1 mRNA
OGG1 protein inhibits the reaction [Cacodylic Acid results in decreased expression of HSPB1 mRNA]
CTD PMID:17441966 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression EXP Cacodylic Acid results in increased expression of HSPD1 mRNA CTD PMID:16122865 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 increases expression EXP Cacodylic Acid results in increased expression of HSPE1 mRNA CTD PMID:16122865 NCBI chr 9:61,691,246...61,724,948
Ensembl chr 9:61,692,154...61,694,599
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 decreases expression
multiple interactions
ISO Cacodylic Acid results in decreased expression of HSPH1 mRNA
OGG1 protein inhibits the reaction [Cacodylic Acid results in decreased expression of HSPH1 mRNA]
CTD PMID:17441966 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Icam5 intercellular adhesion molecule 5 multiple interactions ISO [Arsenic results in increased abundance of Cacodylic Acid] which affects the expression of ICAM5 mRNA CTD PMID:28793237 NCBI chr 8:22,050,222...22,057,209
Ensembl chr 8:22,050,222...22,057,209
JBrowse link
G Igf1r insulin-like growth factor 1 receptor increases expression EXP Cacodylic Acid results in increased expression of IGF1R mRNA CTD PMID:17481689 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression ISO Cacodylic Acid results in increased expression of IGFBP1 mRNA CTD PMID:15345372 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta increases expression EXP Cacodylic Acid results in increased expression of IKBKB protein CTD PMID:26617437 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Il17a interleukin 17A multiple interactions ISO [Arsenic results in increased abundance of Cacodylic Acid] which affects the expression of IL17A mRNA CTD PMID:28793237 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il18rap interleukin 18 receptor accessory protein multiple interactions ISO [Arsenic results in increased abundance of Cacodylic Acid] which affects the expression of IL18RAP mRNA CTD PMID:28793237 NCBI chr 9:47,225,543...47,255,805
Ensembl chr 9:47,225,585...47,258,503
JBrowse link
G Il1b interleukin 1 beta increases secretion EXP Cacodylic Acid results in increased secretion of IL1B protein CTD PMID:26617437 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il24 interleukin 24 increases expression ISO Cacodylic Acid results in increased expression of IL24 mRNA CTD PMID:17720352 NCBI chr13:47,618,451...47,623,849
Ensembl chr13:47,618,452...47,623,849
JBrowse link
G Inhbe inhibin subunit beta E decreases expression EXP Cacodylic Acid results in decreased expression of INHBE mRNA CTD PMID:16122865 NCBI chr 7:70,641,423...70,642,848
Ensembl chr 7:70,640,075...70,643,169
JBrowse link
G Irf1 interferon regulatory factor 1 increases expression EXP Cacodylic Acid results in increased expression of IRF1 mRNA CTD PMID:16122865 NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531
JBrowse link
G Irf5 interferon regulatory factor 5 decreases expression ISO Cacodylic Acid results in decreased expression of IRF5 mRNA CTD PMID:17720352 NCBI chr 4:56,804,477...56,816,271
Ensembl chr 4:56,805,132...56,820,543
JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression
increases expression
EXP Cacodylic Acid results in decreased expression of ITGB1 mRNA
Cacodylic Acid results in increased expression of ITGB1 mRNA
CTD PMID:16122865, PMID:17720352 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Itgb6 integrin subunit beta 6 decreases expression EXP Cacodylic Acid results in decreased expression of ITGB6 mRNA CTD PMID:17720352 NCBI chr 3:46,652,624...46,775,362
Ensembl chr 3:46,652,623...46,726,958
JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 increases expression EXP Cacodylic Acid results in increased expression of ITIH3 mRNA CTD PMID:17481689 NCBI chr16:6,983,779...7,007,288
Ensembl chr16:6,992,062...7,007,287
JBrowse link
G Jag1 jagged canonical Notch ligand 1 decreases expression EXP Cacodylic Acid results in decreased expression of JAG1 mRNA CTD PMID:17720352 NCBI chr 3:130,079,361...130,114,781
Ensembl chr 3:130,079,361...130,114,770
JBrowse link
G Jak2 Janus kinase 2 decreases expression EXP Cacodylic Acid results in decreased expression of JAK2 mRNA CTD PMID:17720352 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of JUN mRNA CTD PMID:23192986 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kb15 type II keratin Kb15 increases expression ISO Cacodylic Acid results in increased expression of KRT6A mRNA CTD PMID:32052077 NCBI chr 7:143,208,034...143,217,771
Ensembl chr 7:143,208,527...143,217,535
JBrowse link
G Kdm5d lysine demethylase 5D increases expression ISO Cacodylic Acid results in increased expression of KDM5D mRNA CTD PMID:22246474 NCBI chr  Y:501,058...589,267
Ensembl chr  Y:505,996...589,267
JBrowse link
G Kif1b kinesin family member 1B increases expression EXP Cacodylic Acid results in increased expression of KIF1B mRNA CTD PMID:17720352 NCBI chr 5:165,994,803...166,133,497
Ensembl chr 5:165,938,576...166,133,491
JBrowse link
G Kpnb1 karyopherin subunit beta 1 increases expression
multiple interactions
ISO Cacodylic Acid results in increased expression of KPNB1 mRNA
OGG1 protein inhibits the reaction [Cacodylic Acid results in increased expression of KPNB1 mRNA]
CTD PMID:17441966 NCBI chr10:85,096,517...85,124,641
Ensembl chr10:85,093,841...85,124,644
JBrowse link
G Krt10 keratin 10 increases expression ISO Cacodylic Acid results in increased expression of KRT10 mRNA CTD PMID:32052077 NCBI chr10:87,296,445...87,301,307
Ensembl chr10:87,296,451...87,300,736
JBrowse link
G Krt13 keratin 13 increases expression ISO Cacodylic Acid results in increased expression of KRT13 mRNA CTD PMID:32052077 NCBI chr10:88,032,130...88,036,040
Ensembl chr10:88,032,130...88,036,040
JBrowse link
G Krt15 keratin 15 increases expression ISO Cacodylic Acid results in increased expression of KRT15 mRNA CTD PMID:32052077 NCBI chr10:88,046,803...88,050,622
Ensembl chr10:88,046,803...88,050,622
JBrowse link
G Krt18 keratin 18 decreases expression
increases expression
EXP
ISO
Cacodylic Acid results in decreased expression of KRT18 mRNA
Cacodylic Acid results in increased expression of KRT18 mRNA
CTD PMID:17481689, PMID:32052077 NCBI chr 7:143,629,455...143,633,131
Ensembl chr 7:143,629,455...143,633,131
JBrowse link
G Krt25 keratin 25 increases expression ISO Cacodylic Acid results in increased expression of KRT25 mRNA CTD PMID:22246474 NCBI chr10:87,225,361...87,238,659
Ensembl chr10:87,225,343...87,232,723
JBrowse link
G Krt4 keratin 4 increases expression ISO Cacodylic Acid results in increased expression of KRT4 mRNA CTD PMID:32052077 NCBI chr 7:143,517,562...143,523,522
Ensembl chr 7:143,518,010...143,523,503
JBrowse link
G Krt8 keratin 8 increases expression ISO Cacodylic Acid results in increased expression of KRT8 mRNA; Cacodylic Acid results in increased expression of KRT8 protein CTD PMID:32052077 NCBI chr 7:143,596,511...143,603,745
Ensembl chr 7:143,596,511...143,603,803
JBrowse link
G Krtap14 keratin associated protein 14 increases expression ISO Cacodylic Acid results in increased expression of KRTAP14 mRNA CTD PMID:22246474 NCBI chr11:28,776,761...28,777,603
Ensembl chr11:28,776,761...28,777,603
JBrowse link
G Krtap8-1 keratin associated protein 8-1 increases expression ISO Cacodylic Acid results in increased expression of KRTAP8-1 mRNA CTD PMID:22246474 NCBI chr11:29,618,650...29,618,941
Ensembl chr11:29,618,672...29,618,857
JBrowse link
G Krtcap2 keratinocyte associated protein 2 decreases expression ISO Cacodylic Acid results in decreased expression of KRTCAP2 mRNA CTD PMID:32052077 NCBI chr 2:188,561,548...188,565,544
Ensembl chr 2:188,561,429...188,565,544
JBrowse link
G Lbp lipopolysaccharide binding protein decreases expression ISO Cacodylic Acid results in decreased expression of LBP mRNA CTD PMID:32052077 NCBI chr 3:154,786,232...154,812,910
Ensembl chr 3:154,786,215...154,813,464
JBrowse link
G Lgals3 galectin 3 increases expression EXP Cacodylic Acid results in increased expression of LGALS3 mRNA CTD PMID:16122865 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
JBrowse link
G Lgals8 galectin 8 multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of LGALS8 mRNA CTD PMID:23192986 NCBI chr17:66,487,451...66,515,316
Ensembl chr17:66,487,457...66,511,870
JBrowse link
G Lman1 lectin, mannose-binding, 1 increases expression EXP Cacodylic Acid results in increased expression of LMAN1 mRNA CTD PMID:16122865 NCBI chr18:61,683,377...61,707,344
Ensembl chr18:61,685,117...61,707,317
JBrowse link
G LOC102551453 keratin, type II cytoskeletal 5-like increases expression ISO Cacodylic Acid results in increased expression of KRT5 mRNA CTD PMID:32052077 NCBI chr 7:143,290,296...143,317,563
Ensembl chr 7:143,312,546...143,317,707
JBrowse link
G Lpl lipoprotein lipase decreases expression ISO Cacodylic Acid results in decreased expression of LPL mRNA CTD PMID:23221991 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 decreases expression ISO Cacodylic Acid results in decreased expression of MAP3K12 mRNA CTD PMID:17441966 NCBI chr 7:144,102,275...144,120,306
Ensembl chr 7:144,102,680...144,109,116
JBrowse link
G Map3k14 mitogen-activated protein kinase kinase kinase 14 increases expression ISO Cacodylic Acid results in increased expression of MAP3K14 mRNA CTD PMID:17441966 NCBI chr10:91,303,428...91,353,601
Ensembl chr10:91,303,428...91,353,601
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 increases expression ISO Cacodylic Acid results in increased expression of MAP3K5 mRNA CTD PMID:17441966 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Map3k6 mitogen-activated protein kinase kinase kinase 6 decreases expression ISO Cacodylic Acid results in decreased expression of MAP3K6 mRNA CTD PMID:17441966 NCBI chr 5:151,435,679...151,448,329
Ensembl chr 5:151,436,464...151,448,328
JBrowse link
G Map4k1 mitogen activated protein kinase kinase kinase kinase 1 decreases expression ISO Cacodylic Acid results in decreased expression of MAP4K1 mRNA CTD PMID:17720352 NCBI chr 1:87,937,126...87,959,514
Ensembl chr 1:87,938,042...87,959,569
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of MAPK1 mRNA CTD PMID:23192986 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases expression
decreases expression
ISO
EXP
Cacodylic Acid results in increased expression of MAPK8 mRNA
Cacodylic Acid results in decreased expression of MAPK8 mRNA
CTD PMID:17441966, PMID:17481689 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor decreases expression ISO Cacodylic Acid results in decreased expression of MAS1 mRNA CTD PMID:22246474 NCBI chr 1:48,076,761...48,108,218
Ensembl chr 1:48,077,033...48,108,216
JBrowse link
G Mbtps1 membrane-bound transcription factor peptidase, site 1 increases expression EXP Cacodylic Acid results in increased expression of MBTPS1 mRNA CTD PMID:16122865 NCBI chr19:52,146,507...52,206,310
Ensembl chr19:52,146,808...52,206,310
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression
multiple interactions
EXP
ISO
Cacodylic Acid results in increased expression of MDM2 mRNA
[sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of MDM2 mRNA
CTD PMID:17481689, PMID:23192986 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mfap2 microfibril associated protein 2 decreases expression ISO Cacodylic Acid results in decreased expression of MFAP2 mRNA CTD PMID:32052077 NCBI chr 5:159,534,202...159,539,750
Ensembl chr 5:159,534,202...159,539,750
JBrowse link
G Mfge8 milk fat globule EGF and factor V/VIII domain containing increases expression EXP Cacodylic Acid results in increased expression of MFGE8 mRNA CTD PMID:16122865 NCBI chr 1:140,845,478...140,860,882
Ensembl chr 1:140,845,465...140,860,894
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression EXP Cacodylic Acid results in increased expression of MGST1 mRNA CTD PMID:16122865 NCBI chr 4:172,119,382...172,134,609
Ensembl chr 4:172,119,331...172,134,607
JBrowse link
G Mmp13 matrix metallopeptidase 13 increases expression
multiple interactions
ISO Cacodylic Acid results in increased expression of MMP13 mRNA
OGG1 protein inhibits the reaction [Cacodylic Acid results in increased expression of MMP13 mRNA]
CTD PMID:17441966 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
JBrowse link
G Mmp14 matrix metallopeptidase 14 increases expression ISO Cacodylic Acid results in increased expression of MMP14 mRNA CTD PMID:17441966 NCBI chr15:33,074,441...33,083,666
Ensembl chr15:33,074,441...33,083,655
JBrowse link
G Mmp17 matrix metallopeptidase 17 increases expression ISO Cacodylic Acid results in increased expression of MMP17 mRNA CTD PMID:17441966 NCBI chr12:30,353,874...30,356,526
NCBI chr12:30,701,900...30,728,683
Ensembl chr12:30,702,571...30,728,655
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression ISO Cacodylic Acid results in increased expression of MMP9 mRNA CTD PMID:17441966 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Msh2 mutS homolog 2 decreases expression EXP Cacodylic Acid results in decreased expression of MSH2 mRNA CTD PMID:17481689 NCBI chr 6:11,215,951...11,274,916
Ensembl chr 6:11,215,963...11,274,932
JBrowse link
G Mt1 metallothionein 1 increases expression ISO
EXP
Cacodylic Acid results in increased expression of MT1 mRNA
Cacodylic Acid results in increased expression of MT1A mRNA
CTD PMID:16122865, PMID:17441966 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mta1 metastasis associated 1 increases expression EXP Cacodylic Acid results in increased expression of MTA1 mRNA CTD PMID:16122865 NCBI chr 6:137,911,302...137,950,066
Ensembl chr 6:137,924,293...137,950,075
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase multiple interactions ISO [MTR gene SNP affects the susceptibility to Arsenic] which affects the abundance of Cacodylic Acid CTD PMID:28889078 NCBI chr17:66,210,444...66,295,014
Ensembl chr17:66,210,461...66,295,014
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of MYC mRNA CTD PMID:23192986 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nbl1 NBL1, DAN family BMP antagonist increases expression EXP Cacodylic Acid results in increased expression of NBL1 mRNA CTD PMID:16122865 NCBI chr 5:157,524,569...157,535,701
Ensembl chr 5:157,524,513...157,535,664
JBrowse link
G Neo1 neogenin 1 increases expression ISO Cacodylic Acid results in increased expression of NEO1 mRNA CTD PMID:22246474 NCBI chr 8:63,649,871...63,756,394
Ensembl chr 8:63,653,266...63,750,531
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions ISO Cacodylic Acid results in increased expression of and affects the localization of NFE2L2 protein; NFE2L2 mutant form inhibits the reaction [Cacodylic Acid results in increased expression of NQO1 protein] CTD PMID:24161444 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfia nuclear factor I/A increases expression EXP Cacodylic Acid results in increased expression of NFIA mRNA CTD PMID:17720352 NCBI chr 5:116,421,895...116,750,381
Ensembl chr 5:116,420,690...116,751,416
JBrowse link
G Nfic nuclear factor I/C increases expression EXP Cacodylic Acid results in increased expression of NFIC mRNA CTD PMID:16122865 NCBI chr 7:11,151,941...11,179,544
Ensembl chr 7:11,152,038...11,177,664
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
increases expression
ISO
EXP
[sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of NFKB1 mRNA
Cacodylic Acid results in increased expression of NFKB1 mRNA
Cacodylic Acid results in increased expression of and affects the localization of NFKB1 protein
CTD PMID:23192986, PMID:26617437 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Ninj1 ninjurin 1 increases expression EXP Cacodylic Acid results in increased expression of NINJ1 mRNA CTD PMID:16122865 NCBI chr17:15,866,235...15,881,284
Ensembl chr17:15,866,237...15,881,327
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 multiple interactions ISO [Arsenic results in increased abundance of Cacodylic Acid] which affects the expression of NOD2 mRNA CTD PMID:28793237 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492
JBrowse link
G Notch1 notch receptor 1 affects expression EXP Cacodylic Acid affects the expression of NOTCH1 mRNA CTD PMID:17720352 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Notch3 notch receptor 3 increases expression EXP Cacodylic Acid results in increased expression of NOTCH3 mRNA CTD PMID:17720352 NCBI chr 7:14,138,495...14,189,688
Ensembl chr 7:14,138,495...14,189,688
JBrowse link
G Nppa natriuretic peptide A increases expression ISO Cacodylic Acid results in increased expression of NPPA mRNA CTD PMID:32052077 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Npy5r neuropeptide Y receptor Y5 decreases expression ISO Cacodylic Acid results in decreased expression of NPY5R mRNA CTD PMID:22246474 NCBI chr16:24,796,685...24,805,730
Ensembl chr16:24,797,124...24,805,079
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions
ISO Cacodylic Acid results in increased expression of NQO1 mRNA
Cacodylic Acid promotes the reaction [sulforafan results in increased expression of and results in increased activity of NQO1 protein]; Cacodylic Acid promotes the reaction [sulforafan results in increased expression of NQO1 mRNA]; Cacodylic Acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of NQO1 protein]; Cacodylic Acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Cacodylic Acid results in increased expression of and results in increased activity of NQO1 protein; NFE2L2 mutant form inhibits the reaction [Cacodylic Acid results in increased expression of NQO1 protein]
CTD PMID:15345372, PMID:24161444 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nrg1 neuregulin 1 increases expression ISO Cacodylic Acid results in increased expression of NRG1 mRNA CTD PMID:17720352 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Oaz1 ornithine decarboxylase antizyme 1 decreases expression ISO Cacodylic Acid results in decreased expression of OAZ1 mRNA CTD PMID:17441966 NCBI chr 7:11,752,127...11,754,587
Ensembl chr 7:11,752,412...11,754,508
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase multiple interactions
increases expression
ISO
EXP
OGG1 protein inhibits the reaction [Cacodylic Acid results in decreased expression of HSPA1B mRNA]; OGG1 protein inhibits the reaction [Cacodylic Acid results in decreased expression of HSPA4L mRNA]; OGG1 protein inhibits the reaction [Cacodylic Acid results in decreased expression of HSPA8 mRNA]; OGG1 protein inhibits the reaction [Cacodylic Acid results in decreased expression of HSPB1 mRNA]; OGG1 protein inhibits the reaction [Cacodylic Acid results in decreased expression of HSPH1 mRNA]; OGG1 protein inhibits the reaction [Cacodylic Acid results in increased expression of AOC3 mRNA]; OGG1 protein inhibits the reaction [Cacodylic Acid results in increased expression of CCNC mRNA]; OGG1 protein inhibits the reaction [Cacodylic Acid results in increased expression of CDH4 mRNA]; OGG1 protein inhibits the reaction [Cacodylic Acid results in increased expression of CFD mRNA]; OGG1 protein inhibits the reaction [Cacodylic Acid results in increased expression of CYP7B1 mRNA]; OGG1 protein inhibits the reaction [Cacodylic Acid results in increased expression of KPNB1 mRNA]; OGG1 protein inhibits the reaction [Cacodylic Acid results in increased expression of MMP13 mRNA]
Cacodylic Acid results in increased expression of OGG1 mRNA
CTD PMID:17441966, PMID:17481689 NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326
JBrowse link
G Pacsin2 protein kinase C and casein kinase substrate in neurons 2 increases expression EXP Cacodylic Acid results in increased expression of PACSIN2 mRNA CTD PMID:16122865 NCBI chr 7:124,224,210...124,317,407
Ensembl chr 7:124,223,633...124,317,379
JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 decreases expression EXP Cacodylic Acid results in decreased expression of PAK2 mRNA CTD PMID:17720352 NCBI chr11:72,829,407...72,865,815
Ensembl chr11:72,829,238...72,865,902
JBrowse link
G Pappa1 pappalysin 1 increases expression ISO Cacodylic Acid results in increased expression of PAPPA mRNA CTD PMID:32052077 NCBI chr 5:80,919,932...81,153,904
Ensembl chr 5:80,920,568...81,150,940
JBrowse link
G Pcdh1 protocadherin 1 decreases expression ISO Cacodylic Acid results in decreased expression of PCDH1 mRNA CTD PMID:17720352 NCBI chr18:31,330,081...31,343,147
Ensembl chr18:31,328,919...31,343,797
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 increases expression ISO Cacodylic Acid results in increased expression of PCK1 mRNA CTD PMID:17441966 NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871
JBrowse link
G Pcna proliferating cell nuclear antigen increases expression EXP Cacodylic Acid results in increased expression of PCNA mRNA; Cacodylic Acid results in increased expression of PCNA protein CTD PMID:17481689, PMID:24832369 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pdcd2 programmed cell death 2 increases expression EXP Cacodylic Acid results in increased expression of PDCD2 mRNA CTD PMID:16122865 NCBI chr 1:57,512,968...57,518,458
Ensembl chr 1:57,512,968...57,518,458
JBrowse link
G Pde3b phosphodiesterase 3B decreases expression EXP Cacodylic Acid results in decreased expression of PDE3B mRNA CTD PMID:16122865 NCBI chr 1:183,892,841...184,078,071
Ensembl chr 1:183,892,841...184,078,071
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 decreases expression EXP Cacodylic Acid results in decreased expression of PDK4 mRNA CTD PMID:16122865 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link
G Per1 period circadian regulator 1 decreases expression ISO Cacodylic Acid results in decreased expression of PER1 mRNA CTD PMID:32052077 NCBI chr10:55,681,761...55,696,557
Ensembl chr10:55,687,050...55,695,994
JBrowse link
G Phex phosphate regulating endopeptidase homolog, X-linked decreases expression ISO Cacodylic Acid results in decreased expression of PHEX mRNA CTD PMID:32052077 NCBI chr  X:40,460,047...40,717,982
Ensembl chr  X:40,460,047...40,717,982
JBrowse link
G Pla2g1b phospholipase A2 group IB decreases expression ISO Cacodylic Acid results in decreased expression of PLA2G1B mRNA CTD PMID:32052077 NCBI chr12:46,879,346...46,890,234
Ensembl chr12:46,879,343...46,889,082
JBrowse link
G Pla2g7 phospholipase A2 group VII increases expression ISO Cacodylic Acid results in increased expression of PLA2G7 mRNA CTD PMID:17441966 NCBI chr 9:19,935,754...19,978,013
Ensembl chr 9:19,935,768...19,978,013
JBrowse link
G Plau plasminogen activator, urokinase multiple interactions ISO [Arsenic results in increased abundance of Cacodylic Acid] which affects the expression of PLAU mRNA CTD PMID:28793237 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Pld2 phospholipase D2 increases expression EXP Cacodylic Acid results in increased expression of PLD2 mRNA CTD PMID:17720352 NCBI chr10:57,161,921...57,181,148
Ensembl chr10:57,163,174...57,179,730
JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit increases expression ISO Cacodylic Acid results in increased expression of POLA1 mRNA CTD PMID:17441966 NCBI chr  X:62,382,604...62,698,830
Ensembl chr  X:62,382,608...62,698,830
JBrowse link
G Pold1 DNA polymerase delta 1, catalytic subunit increases expression EXP Cacodylic Acid results in increased expression of POLD1 mRNA CTD PMID:17720352 NCBI chr 1:100,538,066...100,554,105
Ensembl chr 1:100,537,900...100,554,488
JBrowse link
G Pold4 DNA polymerase delta 4, accessory subunit increases expression ISO Cacodylic Acid results in increased expression of POLD4 mRNA CTD PMID:17441966 NCBI chr 1:219,480,841...219,483,244
Ensembl chr 1:219,481,575...219,483,241
JBrowse link
G Pole2 DNA polymerase epsilon 2, accessory subunit increases expression ISO Cacodylic Acid results in increased expression of POLE2 mRNA CTD PMID:17441966 NCBI chr 6:91,494,348...91,532,355
Ensembl chr 6:91,494,393...91,518,996
JBrowse link
G Polg DNA polymerase gamma, catalytic subunit increases expression ISO Cacodylic Acid results in increased expression of POLG mRNA CTD PMID:17441966 NCBI chr 1:141,172,117...141,188,893
Ensembl chr 1:141,172,531...141,188,031
JBrowse link
G Poli DNA polymerase iota increases expression ISO Cacodylic Acid results in increased expression of POLI mRNA CTD PMID:17441966 NCBI chr18:65,749,107...65,768,805
Ensembl chr18:65,748,908...65,768,781
JBrowse link
G Pon1 paraoxonase 1 increases expression ISO Cacodylic Acid results in increased expression of PON1 mRNA CTD PMID:32052077 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Pou3f1 POU class 3 homeobox 1 decreases expression EXP Cacodylic Acid results in decreased expression of POU3F1 mRNA CTD PMID:17720352 NCBI chr 5:142,643,599...142,646,580
Ensembl chr 5:142,643,599...142,646,580
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression
multiple interactions
ISO Cacodylic Acid results in decreased expression of PPARG mRNA
[Arsenic results in increased abundance of Cacodylic Acid] which affects the expression of PPARG mRNA
CTD PMID:23221991, PMID:28793237 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Prdx2 peroxiredoxin 2 increases expression EXP Cacodylic Acid results in increased expression of PRDX2 mRNA CTD PMID:16122865 NCBI chr19:26,084,816...26,090,095
Ensembl chr19:26,084,903...26,090,094
JBrowse link
G Preb prolactin regulatory element binding increases expression EXP Cacodylic Acid results in increased expression of PREB mRNA CTD PMID:16122865 NCBI chr 6:26,784,088...26,787,875
Ensembl chr 6:26,784,088...26,787,874
JBrowse link
G Prkca protein kinase C, alpha increases expression EXP Cacodylic Acid results in increased expression of PRKCA mRNA CTD PMID:17481689 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947
JBrowse link
G Prkcg protein kinase C, gamma increases expression EXP Cacodylic Acid results in increased expression of PRKCG mRNA CTD PMID:17481689 NCBI chr 1:64,407,098...64,433,698
Ensembl chr 1:64,407,114...64,433,636
JBrowse link
G Prkcz protein kinase C, zeta increases expression EXP Cacodylic Acid results in increased expression of PRKCZ mRNA CTD PMID:16122865 NCBI chr 5:172,658,071...172,769,492
Ensembl chr 5:172,658,748...172,769,421
JBrowse link
G Psca prostate stem cell antigen increases expression ISO Cacodylic Acid results in increased expression of PSCA mRNA CTD PMID:32052077 NCBI chr 7:116,090,189...116,091,955
Ensembl chr 7:116,090,189...116,091,955
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression EXP Cacodylic Acid results in increased expression of PTGS2 mRNA; Cacodylic Acid results in increased expression of PTGS2 protein CTD PMID:12151359, PMID:24832369 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta increases expression EXP Cacodylic Acid results in increased expression of PTK2B mRNA CTD PMID:16122865 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656
JBrowse link
G Rab10 RAB10, member RAS oncogene family increases expression EXP Cacodylic Acid results in increased expression of RAB10 mRNA CTD PMID:16122865 NCBI chr 6:27,668,387...27,721,120
Ensembl chr 6:27,668,403...27,721,120
JBrowse link
G Rab14 RAB14, member RAS oncogene family increases expression
decreases expression
EXP Cacodylic Acid results in increased expression of RAB14 mRNA
Cacodylic Acid results in decreased expression of RAB14 mRNA
CTD PMID:16122865, PMID:17720352 NCBI chr 3:14,373,270...14,395,357
Ensembl chr 3:14,373,275...14,395,362
JBrowse link
G Rab1a RAB1A, member RAS oncogene family increases expression EXP Cacodylic Acid results in increased expression of RAB1A mRNA CTD PMID:16122865 NCBI chr14:104,475,082...104,500,176
Ensembl chr14:104,475,082...104,501,020
JBrowse link
G Rab7a RAB7A, member RAS oncogene family decreases expression
increases expression
ISO
EXP
Cacodylic Acid results in decreased expression of RAB7 mRNA
Cacodylic Acid results in increased expression of RAB7 mRNA
CTD PMID:16122865, PMID:17720352 NCBI chr 4:119,910,461...119,963,065
Ensembl chr 4:119,910,478...119,959,173
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of RAF1 mRNA CTD PMID:23192986 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
G Ralgds ral guanine nucleotide dissociation stimulator increases expression EXP Cacodylic Acid results in increased expression of RALGDS mRNA CTD PMID:16122865 NCBI chr 3:7,090,134...7,130,548
Ensembl chr 3:7,109,920...7,130,548
JBrowse link
G Ramp1 receptor activity modifying protein 1 increases expression EXP Cacodylic Acid results in increased expression of RAMP1 mRNA CTD PMID:16122865 NCBI chr 9:98,313,632...98,364,206
Ensembl chr 9:98,313,632...98,364,205
JBrowse link
G Ran RAN, member RAS oncogene family increases expression EXP Cacodylic Acid results in increased expression of RAN mRNA CTD PMID:16122865 NCBI chr12:31,319,556...31,324,105
Ensembl chr12:31,320,624...31,323,810
JBrowse link
G Reg3b regenerating family member 3 beta decreases expression EXP Cacodylic Acid results in decreased expression of REG3B mRNA CTD PMID:16122865 NCBI chr 4:109,467,272...109,470,510
Ensembl chr 4:109,467,272...109,470,510
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of RELA mRNA CTD PMID:23192986 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 decreases expression EXP Cacodylic Acid results in decreased expression of ROCK1 mRNA CTD PMID:17720352 NCBI chr18:1,273,490...1,390,790
Ensembl chr18:1,273,453...1,390,190
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 increases expression EXP Cacodylic Acid results in increased expression of ROCK2 mRNA CTD PMID:16122865 NCBI chr 6:42,180,864...42,289,910
Ensembl chr 6:42,180,894...42,289,908
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 increases expression ISO Cacodylic Acid results in increased expression of RSAD2 mRNA CTD PMID:32052077 NCBI chr 6:45,655,947...45,669,083
Ensembl chr 6:45,655,954...45,669,148
JBrowse link
G Scn2a sodium voltage-gated channel alpha subunit 2 decreases expression EXP Cacodylic Acid results in decreased expression of SCN2A mRNA CTD PMID:16122865 NCBI chr 3:51,687,910...51,822,008
Ensembl chr 3:51,687,809...51,822,250
JBrowse link
G Serping1 serpin family G member 1 multiple interactions ISO [Arsenic results in increased abundance of Cacodylic Acid] which affects the expression of SERPING1 mRNA CTD PMID:28793237 NCBI chr 3:72,161,230...72,171,109
Ensembl chr 3:72,161,189...72,171,078
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 increases expression EXP Cacodylic Acid results in increased expression of SGK1 mRNA CTD PMID:16122865 NCBI chr 1:24,185,451...24,302,309
Ensembl chr 1:24,185,435...24,302,298
JBrowse link
G Sh3bgrl3 SH3 domain binding glutamate-rich protein like 3 decreases expression ISO Cacodylic Acid results in decreased expression of SH3BGRL3 mRNA CTD PMID:32052077 NCBI chr 5:152,357,270...152,358,643
Ensembl chr 5:152,357,270...152,358,643
JBrowse link
G Shq1 SHQ1, H/ACA ribonucleoprotein assembly factor decreases expression ISO Cacodylic Acid results in decreased expression of SHQ1 mRNA CTD PMID:22246474 NCBI chr 4:133,037,515...133,127,183
NCBI chr 4:133,131,711...133,133,170
Ensembl chr 4:133,037,014...133,131,953
JBrowse link
G Slc11a2 solute carrier family 11 member 2 decreases expression EXP Cacodylic Acid results in decreased expression of SLC11A2 mRNA CTD PMID:17720352 NCBI chr 7:142,025,812...142,062,892
Ensembl chr 7:142,025,815...142,063,212
JBrowse link
G Slc15a4 solute carrier family 15 member 4 decreases expression ISO Cacodylic Acid results in decreased expression of SLC15A4 mRNA CTD PMID:17720352 NCBI chr12:32,753,824...32,773,277
Ensembl chr12:32,753,824...32,773,277
JBrowse link
G Slc27a6 solute carrier family 27 member 6 decreases expression ISO Cacodylic Acid results in decreased expression of SLC27A6 mRNA CTD PMID:32052077 NCBI chr18:53,609,497...53,667,833
Ensembl chr18:53,609,214...53,667,970
JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression EXP Cacodylic Acid results in increased expression of SLC2A4 mRNA CTD PMID:17720352 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link
G Slc35d1 solute carrier family 35 member D1 increases expression ISO Cacodylic Acid results in increased expression of SLC35D1 mRNA CTD PMID:17720352 NCBI chr 5:122,700,396...122,746,815
Ensembl chr 5:122,699,587...122,746,839
JBrowse link
G Slc6a14 solute carrier family 6 member 14 increases expression ISO Cacodylic Acid results in increased expression of SLC6A14 mRNA CTD PMID:32052077 NCBI chr  X:120,624,522...120,647,964
Ensembl chr  X:120,624,518...120,649,111
JBrowse link
G Slc6a6 solute carrier family 6 member 6 increases expression EXP Cacodylic Acid results in increased expression of SLC6A6 mRNA CTD PMID:17720352 NCBI chr 4:123,638,619...123,713,469
Ensembl chr 4:123,642,210...123,713,464
JBrowse link
G Snca synuclein alpha decreases expression EXP Cacodylic Acid results in decreased expression of SNCA CTD PMID:25639566 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Sod1 superoxide dismutase 1 increases expression
decreases expression
EXP
ISO
Cacodylic Acid results in increased expression of SOD1 mRNA
Cacodylic Acid results in decreased expression of SOD1 mRNA
CTD PMID:16122865, PMID:17441966 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Spon1 spondin 1 decreases expression EXP Cacodylic Acid results in decreased expression of SPON1 mRNA CTD PMID:16122865 NCBI chr 1:178,568,777...178,935,715
Ensembl chr 1:178,636,544...178,935,051
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of SRC mRNA CTD PMID:23192986 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of STAT3 mRNA CTD PMID:23192986 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Stc1 stanniocalcin 1 decreases expression ISO Cacodylic Acid results in decreased expression of STC1 mRNA CTD PMID:32052077 NCBI chr15:50,891,137...50,901,791
Ensembl chr15:50,891,127...50,903,162
JBrowse link
G Tgfa transforming growth factor alpha increases expression ISO Cacodylic Acid results in increased expression of TGFA mRNA CTD PMID:17720352 NCBI chr 4:117,961,877...118,045,923
Ensembl chr 4:117,962,319...118,046,344
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
increases secretion
ISO
EXP
[sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of TGFB1 mRNA
Cacodylic Acid results in increased secretion of TGFB1 protein
CTD PMID:23192986, PMID:24832369 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 decreases expression ISO Cacodylic Acid results in decreased expression of TGFBR1 mRNA CTD PMID:17441966 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 increases expression EXP Cacodylic Acid results in increased expression of TGFBR2 mRNA CTD PMID:17481689 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494
JBrowse link
G Thbd thrombomodulin multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of THBD mRNA CTD PMID:23192986 NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325
JBrowse link
G Thy1 Thy-1 cell surface antigen multiple interactions ISO [Arsenic results in increased abundance of Cacodylic Acid] which affects the expression of THY1 mRNA CTD PMID:28793237 NCBI chr 8:48,382,121...48,387,271
Ensembl chr 8:48,382,121...48,386,935
JBrowse link
G Tmem98 transmembrane protein 98 decreases expression ISO Cacodylic Acid results in decreased expression of TMEM98 mRNA CTD PMID:32052077 NCBI chr10:68,173,380...68,184,289
Ensembl chr10:68,173,369...68,184,320
JBrowse link
G Tnf tumor necrosis factor decreases secretion
decreases expression
ISO
EXP
Cacodylic Acid results in decreased secretion of TNF protein
Cacodylic Acid results in decreased expression of TNF protein
CTD PMID:9548797, PMID:24832369 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A decreases expression EXP Cacodylic Acid results in decreased expression of TNFRSF1A mRNA CTD PMID:17481689 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO [Arsenic results in increased abundance of Cacodylic Acid] which affects the expression of TNFSF11 mRNA CTD PMID:28793237 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704
JBrowse link
G Top2a DNA topoisomerase II alpha increases expression
decreases expression
ISO
EXP
Cacodylic Acid results in increased expression of TOP2A mRNA
Cacodylic Acid results in decreased expression of TOP2A mRNA
CTD PMID:17441966, PMID:17720352 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
JBrowse link
G Tp53 tumor protein p53 increases expression
multiple interactions
EXP
ISO
Cacodylic Acid results in increased expression of TP53 mRNA
[sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of TP53 mRNA
CTD PMID:17720352, PMID:23192986 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Traf3 Tnf receptor-associated factor 3 decreases expression ISO Cacodylic Acid results in decreased expression of TRAF3 mRNA CTD PMID:15345372 NCBI chr 6:135,610,698...135,720,247
Ensembl chr 6:135,610,743...135,718,564
JBrowse link
G Tshr thyroid stimulating hormone receptor decreases expression EXP Cacodylic Acid results in decreased expression of TSHR mRNA CTD PMID:16122865 NCBI chr 6:115,170,290...115,306,871
Ensembl chr 6:115,170,865...115,306,871
JBrowse link
G Ttn titin increases expression ISO Cacodylic Acid results in increased expression of TTN mRNA CTD PMID:17441966 NCBI chr 3:63,565,160...63,837,815 JBrowse link
G Txn1 thioredoxin 1 increases expression
multiple interactions
EXP
ISO
Cacodylic Acid results in increased expression of TXN1 mRNA
[sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of TXN mRNA
CTD PMID:16122865, PMID:23192986 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
G Txn2 thioredoxin 2 increases expression EXP Cacodylic Acid results in increased expression of TXN2 mRNA CTD PMID:16122865 NCBI chr 7:119,144,350...119,158,173
Ensembl chr 7:119,144,351...119,158,201
JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of TXNRD1 mRNA CTD PMID:23192986 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Ubd ubiquitin D increases expression EXP Cacodylic Acid results in increased expression of UBD mRNA CTD PMID:17720352 NCBI chr20:1,876,175...1,878,126
Ensembl chr20:1,876,173...1,897,814
JBrowse link
G Ube2d3 ubiquitin-conjugating enzyme E2D 3 increases expression EXP Cacodylic Acid results in increased expression of UBE2D3 mRNA CTD PMID:17720352 NCBI chr 2:240,626,198...240,655,874
Ensembl chr 2:240,627,436...240,655,246
JBrowse link
G Ube2g2 ubiquitin-conjugating enzyme E2G 2 decreases expression ISO Cacodylic Acid results in decreased expression of UBE2G2 mRNA CTD PMID:22246474 NCBI chr20:11,700,089...11,721,823
Ensembl chr20:11,700,089...11,721,838
JBrowse link
G Upk1a uroplakin 1A decreases expression ISO Cacodylic Acid results in decreased expression of UPK1A mRNA CTD PMID:32052077 NCBI chr 1:89,060,581...89,071,579
Ensembl chr 1:89,060,581...89,068,348
JBrowse link
G Usf2 upstream transcription factor 2, c-fos interacting increases expression EXP Cacodylic Acid results in increased expression of USF2 mRNA CTD PMID:16122865 NCBI chr 1:89,371,798...89,383,005
Ensembl chr 1:89,371,794...89,382,463
JBrowse link
G Usp2 ubiquitin specific peptidase 2 increases expression EXP Cacodylic Acid results in increased expression of USP2 mRNA CTD PMID:17720352 NCBI chr 8:48,403,985...48,432,525
Ensembl chr 8:48,406,260...48,430,885
JBrowse link
G Usp7 ubiquitin specific peptidase 7 increases expression ISO Cacodylic Acid results in increased expression of USP7 mRNA CTD PMID:17720352 NCBI chr10:6,930,462...7,019,910
Ensembl chr10:6,975,244...7,018,930
JBrowse link
G Uty ubiquitously transcribed tetratricopeptide repeat containing, Y-linked increases expression ISO Cacodylic Acid results in increased expression of UTY mRNA CTD PMID:22246474 NCBI chr  Y:1,065,274...1,206,127
Ensembl chr  Y:989,240...1,206,096
JBrowse link
G Vdr vitamin D receptor decreases expression EXP Cacodylic Acid results in decreased expression of VDR mRNA CTD PMID:16122865 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
G Vegfc vascular endothelial growth factor C increases expression ISO Cacodylic Acid results in increased expression of VEGFC mRNA CTD PMID:17441966 NCBI chr16:40,440,371...40,555,178
Ensembl chr16:40,440,207...40,555,576
JBrowse link
G Vegfd vascular endothelial growth factor D decreases expression EXP Cacodylic Acid results in decreased expression of VEGFD mRNA CTD PMID:16122865 NCBI chr  X:31,816,480...31,852,239
Ensembl chr  X:31,816,436...31,851,715
JBrowse link
G Wdr83os WD repeat domain 83 opposite strand decreases expression ISO Cacodylic Acid results in decreased expression of WDR83OS mRNA CTD PMID:32052077 NCBI chr19:26,194,336...26,195,837
Ensembl chr19:26,194,465...26,195,837
JBrowse link
G Wnt1 Wnt family member 1 multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of WNT1 mRNA CTD PMID:23192986 NCBI chr 7:140,464,999...140,469,046
Ensembl chr 7:140,464,999...140,469,046
JBrowse link
G Xbp1 X-box binding protein 1 increases expression ISO Cacodylic Acid results in increased expression of XBP1 mRNA; Cacodylic Acid results in increased expression of XBP1 mRNA alternative form CTD PMID:23221991 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta increases expression EXP Cacodylic Acid results in increased expression of YWHAQ mRNA CTD PMID:16122865 NCBI chr 6:43,463,294...43,493,816
Ensembl chr 6:43,463,294...43,493,816
JBrowse link
dimethylarsinous acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 decreases response to substance ISO ABCC1 protein results in decreased susceptibility to dimethylarsinous acid CTD PMID:29752257 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 increases expression ISO dimethylarsinous acid results in increased expression of ALDH1A3 mRNA CTD PMID:20886546 NCBI chr 1:127,302,920...127,337,828
Ensembl chr 1:127,301,128...127,337,882
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member increases expression ISO dimethylarsinous acid results in increased expression of ALDH2 mRNA CTD PMID:23876855 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein decreases expression ISO dimethylarsinous acid results in decreased expression of ALOX5AP mRNA CTD PMID:16507463 NCBI chr12:6,854,930...6,879,112
Ensembl chr12:6,854,920...6,879,154
JBrowse link
G Ankrd1 ankyrin repeat domain 1 increases expression ISO dimethylarsinous acid results in increased expression of ANKRD1 mRNA CTD PMID:23876855 NCBI chr 1:254,726,985...254,745,673
Ensembl chr 1:254,726,969...254,735,548
JBrowse link
G Anos1 anosmin 1 increases expression ISO dimethylarsinous acid results in increased expression of ANOS1 mRNA CTD PMID:23876855 Ensembl chr10:70,999,780...71,000,627 JBrowse link
G Apoe apolipoprotein E affects response to substance ISO APOE protein affects the susceptibility to dimethylarsinous acid CTD PMID:28728140 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G As3mt arsenite methyltransferase increases chemical synthesis
affects response to substance
multiple interactions
ISO AS3MT protein results in increased chemical synthesis of dimethylarsinous acid
AS3MT affects the susceptibility to dimethylarsinous acid
[AS3MT gene SNP affects the susceptibility to Arsenic] which affects the abundance of dimethylarsinous acid; [AS3MT protein binds to and results in increased methylation of arsenite] which results in increased chemical synthesis of dimethylarsinous acid; [AS3MT protein polymorphism results in increased metabolism of arsenite] which results in increased chemical synthesis of dimethylarsinous acid; [AS3MT protein polymorphism results in increased metabolism of monomethylarsonic acid] which results in increased chemical synthesis of dimethylarsinous acid; [AS3MT protein results in increased metabolism of arsenite] which results in increased chemical synthesis of dimethylarsinous acid; [AS3MT protein results in increased metabolism of monomethylarsonic acid] which results in increased chemical synthesis of dimethylarsinous acid; Cysteine promotes the reaction [AS3MT protein results in increased chemical synthesis of dimethylarsinous acid]; Glutathione promotes the reaction [[AS3MT protein polymorphism results in increased metabolism of arsenite] which results in increased chemical synthesis of dimethylarsinous acid]; Glutathione promotes the reaction [AS3MT protein results in increased chemical synthesis of dimethylarsinous acid]; tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein results in increased chemical synthesis of dimethylarsinous acid]
CTD PMID:22868225, PMID:22955273, PMID:23376817, PMID:25349987, PMID:29859237 NCBI chr 1:266,482,787...266,514,570
Ensembl chr 1:266,482,858...266,514,569
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO dimethylarsinous acid results in increased expression of ASNS mRNA CTD PMID:23876855 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Atf4 activating transcription factor 4 increases expression EXP dimethylarsinous acid results in increased expression of ATF4 mRNA CTD PMID:22425709 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Aurkb aurora kinase B affects localization ISO dimethylarsinous acid affects the localization of AURKB protein CTD PMID:19716834 NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO dimethylarsinous acid affects the expression of and affects the cleavage of BAX protein CTD PMID:30262279 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression ISO dimethylarsinous acid results in increased expression of BCL2 protein CTD PMID:30262279 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bhlhe41 basic helix-loop-helix family, member e41 decreases expression ISO dimethylarsinous acid results in decreased expression of BHLHE41 mRNA CTD PMID:23876855 NCBI chr 4:180,230,742...180,235,138
Ensembl chr 4:180,232,382...180,234,804
JBrowse link
G Ca9 carbonic anhydrase 9 decreases expression ISO dimethylarsinous acid results in decreased expression of CA9 mRNA CTD PMID:23876855 NCBI chr 5:59,008,277...59,015,535
Ensembl chr 5:59,008,933...59,015,528
JBrowse link
G Casp1 caspase 1 affects expression ISO dimethylarsinous acid affects the expression of CASP1 mRNA CTD PMID:20886546 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp14 caspase 14 decreases expression ISO dimethylarsinous acid results in decreased expression of CASP14 mRNA CTD PMID:23876855 NCBI chr 7:13,938,376...13,944,286
Ensembl chr 7:13,938,302...13,945,130
JBrowse link
G Casp3 caspase 3 multiple interactions ISO [monomethylarsonous acid co-treated with dimethylarsinous acid co-treated with Arsenic Trioxide] results in increased activity of and results in increased cleavage of CASP3 protein; Acetylcysteine inhibits the reaction [[monomethylarsonous acid co-treated with dimethylarsinous acid co-treated with Arsenic Trioxide] results in increased cleavage of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[monomethylarsonous acid co-treated with dimethylarsinous acid co-treated with Arsenic Trioxide] results in increased cleavage of CASP3 protein] CTD PMID:29774349 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 increases activity ISO dimethylarsinous acid results in increased activity of CASP9 protein CTD PMID:30262279 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase decreases oxidation
multiple interactions
affects activity
EXP
ISO
CAT protein results in decreased oxidation of dimethylarsinous acid
[CAT protein results in decreased oxidation of dimethylarsinous acid] which results in decreased chemical synthesis of Cacodylic Acid
dimethylarsinous acid affects the activity of CAT protein
CTD PMID:18619986, PMID:23353816 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO dimethylarsinous acid results in decreased expression of CCL2 mRNA CTD PMID:16507463 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccna1 cyclin A1 decreases expression ISO dimethylarsinous acid results in decreased expression of CCNA1 mRNA CTD PMID:16507463 NCBI chr 2:144,456,689...144,503,570
Ensembl chr 2:144,458,153...144,467,912
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO dimethylarsinous acid results in increased expression of CCND1 mRNA CTD PMID:19945496 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cd44 CD44 molecule (Indian blood group) increases expression ISO dimethylarsinous acid results in increased expression of CD44 mRNA CTD PMID:20886546 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cdh6 cadherin 6 decreases expression ISO dimethylarsinous acid results in decreased expression of CDH6 mRNA CTD PMID:23876855 NCBI chr 2:63,100,723...63,246,618
Ensembl chr 2:63,101,739...63,166,509
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO dimethylarsinous acid results in decreased expression of CDK4 mRNA CTD PMID:20886546 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO dimethylarsinous acid results in increased expression of CDKN1A mRNA CTD PMID:20886546 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B decreases expression ISO dimethylarsinous acid results in decreased expression of CDKN2B mRNA CTD PMID:19945496 NCBI chr 5:107,834,353...107,857,428
Ensembl chr 5:107,845,951...107,858,104
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta decreases expression ISO dimethylarsinous acid results in decreased expression of CEBPB mRNA CTD PMID:16507463 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Clu clusterin increases expression ISO dimethylarsinous acid results in increased expression of CLU mRNA CTD PMID:20886546, PMID:23876855 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression
increases expression
ISO dimethylarsinous acid results in decreased expression of COL1A1 mRNA
dimethylarsinous acid results in increased expression of COL1A1 mRNA
CTD PMID:16507463, PMID:23876855 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Cryab crystallin, alpha B increases expression ISO dimethylarsinous acid results in increased expression of CRYAB mRNA CTD PMID:20886546, PMID:23876855 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 increases expression ISO dimethylarsinous acid results in increased expression of CXCL14 mRNA CTD PMID:20886546 NCBI chr17:9,109,731...9,117,754
Ensembl chr17:9,109,731...9,117,750
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO dimethylarsinous acid results in increased expression of CYP1A1 mRNA CTD PMID:20886546 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Dapk1 death associated protein kinase 1 affects expression ISO dimethylarsinous acid affects the expression of DAPK mRNA CTD PMID:20886546 NCBI chr17:4,297,038...4,454,941
Ensembl chr17:4,297,224...4,454,778
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 decreases expression
increases expression
ISO
EXP
dimethylarsinous acid results in decreased expression of DDIT3 mRNA
dimethylarsinous acid results in increased expression of DDIT3 mRNA
CTD PMID:16507463, PMID:22425709 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Depdc1 DEP domain containing 1 increases expression ISO dimethylarsinous acid results in increased expression of DEPDC1 mRNA CTD PMID:23876855 NCBI chr 2:264,704,738...264,738,265
Ensembl chr 2:264,704,769...264,738,257
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO dimethylarsinous acid results in increased expression of DUSP1 mRNA CTD PMID:19945496 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Edn1 endothelin 1 increases expression ISO dimethylarsinous acid results in increased expression of EDN1 mRNA CTD PMID:23876855 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Egr1 early growth response 1 decreases expression ISO dimethylarsinous acid results in decreased expression of EGR1 mRNA CTD PMID:23876855 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases phosphorylation
EXP Cycloheximide inhibits the reaction [dimethylarsinous acid results in increased phosphorylation of EIF2AK3 protein] CTD PMID:22425709 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G Etv1 ETS variant transcription factor 1 decreases expression ISO dimethylarsinous acid results in decreased expression of ETV1 mRNA CTD PMID:23876855 NCBI chr 6:58,467,215...58,558,640
Ensembl chr 6:58,467,254...58,558,631
JBrowse link
G Fen1 flap structure-specific endonuclease 1 decreases expression ISO dimethylarsinous acid results in decreased expression of FEN1 mRNA CTD PMID:20886546 NCBI chr 1:226,251,516...226,256,160
Ensembl chr 1:226,251,518...226,255,886
JBrowse link
G Fgfbp1 fibroblast growth factor binding protein 1 decreases expression ISO dimethylarsinous acid results in decreased expression of FGFBP1 mRNA CTD PMID:23876855 NCBI chr14:71,647,429...71,650,359
Ensembl chr14:71,649,274...71,650,354
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 decreases expression ISO dimethylarsinous acid results in decreased expression of FGFR1 mRNA CTD PMID:16507463 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
JBrowse link
G Fn1 fibronectin 1 increases expression ISO dimethylarsinous acid results in increased expression of FN1 mRNA CTD PMID:20886546 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression ISO dimethylarsinous acid results in decreased expression of FOS mRNA CTD PMID:23876855 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO dimethylarsinous acid results in increased expression of FTL mRNA CTD PMID:20886546 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G Gata6 GATA binding protein 6 decreases expression ISO dimethylarsinous acid results in decreased expression of GATA6 mRNA CTD PMID:16507463 NCBI chr18:2,415,821...2,447,087
Ensembl chr18:2,416,552...2,446,338
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression ISO dimethylarsinous acid results in decreased expression of GJA1 mRNA CTD PMID:16507463 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gstm3 glutathione S-transferase mu 3 increases expression ISO dimethylarsinous acid results in increased expression of GSTM3 mRNA CTD PMID:20886546 NCBI chr 2:210,685,204...210,688,273
Ensembl chr 2:210,685,197...210,688,272
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 increases expression ISO dimethylarsinous acid results in increased expression of GSTM3 mRNA CTD PMID:20886546 NCBI chr 2:210,685,338...210,688,133
Ensembl chr 2:210,685,197...210,688,272
JBrowse link
G Gtse1 G-2 and S-phase expressed 1 increases expression ISO dimethylarsinous acid results in increased expression of GTSE1 mRNA CTD PMID:19945496 NCBI chr 7:126,736,416...126,753,221
Ensembl chr 7:126,736,732...126,753,220
JBrowse link
G H1f5 H1.5 linker histone, cluster member increases expression ISO dimethylarsinous acid results in increased expression of H1-5 mRNA CTD PMID:23876855 NCBI chr17:44,766,313...44,766,981
Ensembl chr17:44,766,313...44,766,981
JBrowse link
G H3c1 H3 clustered histone 1 increases expression ISO dimethylarsinous acid results in increased expression of H3C1 mRNA CTD PMID:23876855 NCBI chr17:43,616,206...43,616,735
Ensembl chr17:44,839,721...44,840,131
Ensembl chr17:44,839,721...44,840,131
Ensembl chr17:44,839,721...44,840,131
Ensembl chr17:44,839,721...44,840,131
JBrowse link
G Hbegf heparin-binding EGF-like growth factor decreases expression ISO dimethylarsinous acid results in decreased expression of HBEGF mRNA CTD PMID:16507463 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression ISO dimethylarsinous acid results in decreased expression of HIF1A mRNA CTD PMID:16507463 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hist1h2af histone cluster 1 H2A family member F increases expression ISO dimethylarsinous acid results in increased expression of H2AC8 mRNA CTD PMID:23876855 NCBI chr17:43,627,237...43,627,629
Ensembl chr17:43,627,237...43,627,629
JBrowse link
G Hmgb1 high mobility group box 1 decreases expression ISO dimethylarsinous acid results in decreased expression of HMGB1 mRNA CTD PMID:20886546 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmmr hyaluronan-mediated motility receptor increases expression ISO dimethylarsinous acid results in increased expression of HMMR mRNA CTD PMID:23876855 NCBI chr10:25,861,490...25,890,639
Ensembl chr10:25,861,490...25,890,639
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO dimethylarsinous acid results in increased expression of HMOX1 mRNA CTD PMID:19945496, PMID:23876855 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Ifi44 interferon-induced protein 44 decreases expression ISO dimethylarsinous acid results in decreased expression of IFI44 mRNA CTD PMID:23876855 NCBI chr 2:256,897,765...256,915,591
Ensembl chr 2:256,897,772...256,915,569
JBrowse link
G Ifi44l interferon-induced protein 44-like decreases expression ISO dimethylarsinous acid results in decreased expression of IFI44L mRNA CTD PMID:23876855 NCBI chr 2:256,948,722...256,979,573
Ensembl chr 2:256,964,860...256,978,668
JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 decreases expression ISO dimethylarsinous acid results in decreased expression of IFIT2 mRNA CTD PMID:23876855 NCBI chr 1:252,894,663...252,900,727
Ensembl chr 1:252,894,663...252,900,726
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 increases expression ISO dimethylarsinous acid results in increased expression of IFIT3 mRNA CTD PMID:20886546 NCBI chr 1:252,906,234...252,911,377
Ensembl chr 1:252,906,234...252,911,382
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 decreases expression ISO dimethylarsinous acid results in decreased expression of IGFBP5 mRNA CTD PMID:16507463 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033
JBrowse link
G Il1a interleukin 1 alpha decreases expression ISO dimethylarsinous acid results in decreased expression of IL1A mRNA CTD PMID:19945496 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1r2 interleukin 1 receptor type 2 increases expression ISO dimethylarsinous acid results in increased expression of IL1R2 mRNA CTD PMID:16507463 NCBI chr 9:46,840,646...46,881,241
Ensembl chr 9:46,840,992...46,881,264
JBrowse link
G Il24 interleukin 24 increases expression ISO dimethylarsinous acid results in increased expression of IL24 mRNA CTD PMID:23876855 NCBI chr13:47,618,451...47,623,849
Ensembl chr13:47,618,452...47,623,849
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO [dimethylarsinous acid co-treated with Lipopolysaccharides] results in increased secretion of IL6 protein
dimethylarsinous acid results in increased expression of IL6 mRNA
CTD PMID:23876855, PMID:24140498 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Itgb3 integrin subunit beta 3 decreases expression
increases expression
ISO dimethylarsinous acid results in decreased expression of ITGB3 mRNA
dimethylarsinous acid results in increased expression of ITGB3 mRNA
CTD PMID:16507463, PMID:23876855 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Krt15 keratin 15 decreases expression ISO dimethylarsinous acid results in decreased expression of KRT15 mRNA CTD PMID:23876855 NCBI chr10:88,046,803...88,050,622
Ensembl chr10:88,046,803...88,050,622
JBrowse link
G Krt34 keratin 34 increases expression ISO dimethylarsinous acid results in increased expression of KRT34 mRNA CTD PMID:23876855 NCBI chr10:87,950,364...87,954,055
Ensembl chr10:87,950,001...87,954,055
JBrowse link
G Krt75 keratin 75 increases expression ISO dimethylarsinous acid results in increased expression of KRT75 mRNA CTD PMID:23876855 NCBI chr 7:143,219,012...143,228,237
Ensembl chr 7:143,219,012...143,228,060
JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 increases expression ISO dimethylarsinous acid results in increased expression of LCP1 mRNA CTD PMID:23876855 NCBI chr15:57,170,566...57,277,811
Ensembl chr15:57,221,292...57,277,811
JBrowse link
G LOC102549061 histone H2B type 1-N-like increases expression ISO dimethylarsinous acid results in increased expression of H2BC3 mRNA CTD PMID:23876855 NCBI chr17:43,627,872...43,628,518
Ensembl chr17:43,627,930...43,628,310
JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO dimethylarsinous acid results in increased expression of MMP1 mRNA CTD PMID:23876855 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp10 matrix metallopeptidase 10 increases expression ISO dimethylarsinous acid results in increased expression of MMP10 mRNA CTD PMID:23876855 NCBI chr 8:5,734,348...5,742,243
Ensembl chr 8:5,734,348...5,742,243
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression ISO dimethylarsinous acid results in decreased expression of MMP2 mRNA CTD PMID:16507463 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression ISO dimethylarsinous acid results in increased expression of MMP9 mRNA CTD PMID:23876855 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Msx1 msh homeobox 1 decreases expression ISO dimethylarsinous acid results in decreased expression of MSX1 protein CTD PMID:26024302 NCBI chr14:77,712,262...77,716,061
Ensembl chr14:77,712,240...77,716,059
JBrowse link
G Mx2 MX dynamin like GTPase 2 decreases expression ISO dimethylarsinous acid results in decreased expression of MX1 mRNA CTD PMID:23876855 NCBI chr11:38,035,306...38,066,185
Ensembl chr11:38,035,450...38,059,950
JBrowse link
G Mylk myosin light chain kinase decreases expression ISO dimethylarsinous acid results in decreased expression of MYLK mRNA CTD PMID:16507463 NCBI chr11:69,013,060...69,260,039
Ensembl chr11:69,013,050...69,223,158
JBrowse link
G Myod1 myogenic differentiation 1 affects localization
decreases expression
ISO dimethylarsinous acid affects the localization of MYOD1 protein
dimethylarsinous acid results in decreased expression of MYOD1 protein
CTD PMID:26024302 NCBI chr 1:102,396,538...102,399,248
Ensembl chr 1:102,396,538...102,399,248
JBrowse link
G Myog myogenin decreases expression ISO dimethylarsinous acid results in decreased expression of MYOG protein CTD PMID:26024302 NCBI chr13:51,126,459...51,129,048
Ensembl chr13:51,126,459...51,129,048
JBrowse link
G N6amt1 N-6 adenine-specific DNA methyltransferase 1 multiple interactions ISO [N6AMT1 protein results in increased metabolism of monomethylarsonous acid] which results in increased chemical synthesis of dimethylarsinous acid CTD PMID:21193388 NCBI chr11:27,004,335...27,016,690
Ensembl chr11:27,004,320...27,016,941
JBrowse link
G Neurod1 neuronal differentiation 1 affects localization
decreases expression
ISO dimethylarsinous acid affects the localization of NEUROD1 protein
dimethylarsinous acid results in decreased expression of NEUROD1 protein
CTD PMID:26024302 NCBI chr 3:66,414,314...66,417,617
Ensembl chr 3:66,414,308...66,417,741
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO dimethylarsinous acid results in increased expression of NQO1 mRNA CTD PMID:20886546 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases expression ISO dimethylarsinous acid results in increased expression of NR1I2 mRNA CTD PMID:19084030 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nrg1 neuregulin 1 decreases expression ISO dimethylarsinous acid results in decreased expression of NRG1 mRNA CTD PMID:20886546 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase decreases expression ISO dimethylarsinous acid results in decreased expression of NSF mRNA CTD PMID:16507463 NCBI chr10:91,879,608...91,986,242
Ensembl chr10:91,878,633...92,008,082
JBrowse link
G Nup88 nucleoporin 88 decreases expression ISO dimethylarsinous acid results in decreased expression of NUP88 mRNA CTD PMID:16507463 NCBI chr10:57,581,828...57,606,171
Ensembl chr10:57,581,828...57,606,171
JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A increases expression ISO dimethylarsinous acid results in increased expression of OAS1 mRNA CTD PMID:20886546 NCBI chr12:41,200,680...41,211,393
Ensembl chr12:41,200,718...41,211,909
JBrowse link
G Odc1 ornithine decarboxylase 1 decreases expression ISO dimethylarsinous acid results in decreased expression of ODC1 mRNA CTD PMID:16507463 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases activity
multiple interactions
ISO dimethylarsinous acid results in decreased activity of PARP1 protein
[monomethylarsonous acid co-treated with dimethylarsinous acid co-treated with Arsenic Trioxide] results in increased cleavage of PARP1 protein; Acetylcysteine inhibits the reaction [[monomethylarsonous acid co-treated with dimethylarsinous acid co-treated with Arsenic Trioxide] results in increased cleavage of PARP1 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[monomethylarsonous acid co-treated with dimethylarsinous acid co-treated with Arsenic Trioxide] results in increased cleavage of PARP1 protein]; dimethylarsinous acid inhibits the reaction [Hydrogen Peroxide results in increased activity of PARP1 protein]
CTD PMID:17011244, PMID:29774349 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pdcd1lg2 programmed cell death 1 ligand 2 increases expression ISO dimethylarsinous acid results in increased expression of PDCD1LG2 mRNA CTD PMID:23876855 NCBI chr 1:247,562,202...247,629,279
Ensembl chr 1:247,562,202...247,627,193
JBrowse link
G Pml PML nuclear body scaffold multiple interactions ISO [monomethylarsonous acid co-treated with dimethylarsinous acid co-treated with Arsenic Trioxide] results in increased degradation of PML protein CTD PMID:29774349 NCBI chr 8:63,002,515...63,034,310
Ensembl chr 8:63,004,870...63,034,226
JBrowse link
G Pole2 DNA polymerase epsilon 2, accessory subunit decreases expression ISO dimethylarsinous acid results in decreased expression of POLE2 mRNA CTD PMID:20886546 NCBI chr 6:91,494,348...91,532,355
Ensembl chr 6:91,494,393...91,518,996
JBrowse link
G Pram1 PML-RARA regulated adaptor molecule 1 multiple interactions ISO [monomethylarsonous acid co-treated with dimethylarsinous acid co-treated with Arsenic Trioxide] results in increased expression of PRAM1 protein CTD PMID:29774349 NCBI chr 7:18,507,878...18,516,321
Ensembl chr 7:18,510,354...18,515,503
JBrowse link
G Prkca protein kinase C, alpha decreases expression ISO dimethylarsinous acid results in decreased expression of PRKCA mRNA CTD PMID:16507463 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947
JBrowse link
G Psma3 proteasome 20S subunit alpha 3 decreases expression ISO dimethylarsinous acid results in decreased expression of PSMA3 mRNA CTD PMID:16507463 NCBI chr 6:93,423,029...93,444,223
Ensembl chr 6:93,423,002...93,444,240
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO dimethylarsinous acid results in increased expression of PTGS2 mRNA CTD PMID:23876855 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 affects binding
decreases activity
ISO dimethylarsinous acid binds to PTPN1 protein
dimethylarsinous acid results in decreased activity of PTPN1 protein
CTD PMID:22771847 NCBI chr 3:164,665,462...164,711,936
Ensembl chr 3:164,665,532...164,711,848
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C decreases activity ISO dimethylarsinous acid results in decreased activity of PTPRC protein CTD PMID:22771847 NCBI chr13:55,061,561...55,174,150
Ensembl chr13:55,061,562...55,173,692
JBrowse link
G Ptprz1 protein tyrosine phosphatase, receptor type Z1 decreases expression ISO dimethylarsinous acid results in decreased expression of PTPRZ1 mRNA CTD PMID:23876855 NCBI chr 4:49,941,046...50,140,764
Ensembl chr 4:49,941,304...50,140,762
JBrowse link
G Rhod ras homolog family member D increases expression ISO dimethylarsinous acid results in increased expression of RHOD mRNA CTD PMID:20886546 NCBI chr 1:219,668,352...219,682,287
Ensembl chr 1:219,668,352...219,682,287
JBrowse link
G Rpusd4 RNA pseudouridine synthase D4 decreases expression ISO dimethylarsinous acid results in decreased expression of RPUSD4 mRNA CTD PMID:16507463 NCBI chr 8:36,467,706...36,477,190
Ensembl chr 8:36,467,706...36,477,189
JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B increases expression ISO dimethylarsinous acid results in increased expression of RRM2B mRNA CTD PMID:20886546 NCBI chr 7:76,750,045...76,780,817
Ensembl chr 7:76,750,050...76,780,817
JBrowse link
G Rxra retinoid X receptor alpha increases expression ISO dimethylarsinous acid results in increased expression of RXRA mRNA CTD PMID:19084030 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G S100a8 S100 calcium binding protein A8 decreases expression ISO dimethylarsinous acid results in decreased expression of S100A8 mRNA CTD PMID:23876855 NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354
JBrowse link
G Serpinb2 serpin family B member 2 increases expression ISO dimethylarsinous acid results in increased expression of SERPINB2 mRNA CTD PMID:23876855 NCBI chr13:27,449,907...27,463,015
Ensembl chr13:27,449,934...27,463,010
JBrowse link
G Serpinb7 serpin family B member 7 increases expression ISO dimethylarsinous acid results in increased expression of SERPINB7 mRNA CTD PMID:23876855 NCBI chr13:27,282,456...27,354,775
Ensembl chr13:27,312,498...27,354,052
JBrowse link
G Skp1 S-phase kinase-associated protein 1 increases expression ISO dimethylarsinous acid results in increased expression of SKP1 mRNA CTD PMID:20886546 NCBI chr10:37,594,578...37,609,498
Ensembl chr10:37,594,578...37,609,498
JBrowse link
G Skp2 S-phase kinase associated protein 2 increases expression ISO dimethylarsinous acid results in increased expression of SKP2 mRNA CTD PMID:19945496 NCBI chr 2:58,506,146...58,534,211
Ensembl chr 2:58,506,151...58,534,211
JBrowse link
G Slitrk6 SLIT and NTRK-like family, member 6 decreases expression ISO dimethylarsinous acid results in decreased expression of SLITRK6 mRNA CTD PMID:23876855 NCBI chr15:95,507,632...95,514,259
Ensembl chr15:95,507,640...95,514,259
JBrowse link
G Smad7 SMAD family member 7 decreases expression ISO dimethylarsinous acid results in decreased expression of SMAD7 mRNA CTD PMID:16507463 NCBI chr18:71,395,830...71,424,164
Ensembl chr18:71,395,830...71,424,157
JBrowse link
G Sod1 superoxide dismutase 1 increases expression
increases response to substance
ISO dimethylarsinous acid results in increased expression of SOD1 mRNA
SOD1 protein results in increased susceptibility to dimethylarsinous acid
CTD PMID:20740636, PMID:20886546 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 increases expression ISO dimethylarsinous acid results in increased expression of SOD2 mRNA CTD PMID:19945496 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sox10 SRY-box transcription factor 10 decreases expression ISO dimethylarsinous acid results in decreased expression of SOX10 protein CTD PMID:26024302 NCBI chr 7:120,393,238...120,403,523
Ensembl chr 7:120,393,254...120,403,523
JBrowse link
G Stat1 signal transducer and activator of transcription 1 increases expression ISO dimethylarsinous acid results in increased expression of STAT1 mRNA CTD PMID:20886546 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Strn3 striatin 3 affects expression ISO dimethylarsinous acid affects the expression of STRN3 mRNA CTD PMID:20886546 NCBI chr 6:72,376,360...72,462,676
Ensembl chr 6:72,376,330...72,462,658
JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 decreases expression ISO dimethylarsinous acid results in decreased expression of SULT1B1 mRNA CTD PMID:23876855 NCBI chr14:22,142,412...22,155,246
Ensembl chr14:22,142,364...22,155,231
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 multiple interactions ISO [monomethylarsonous acid co-treated with dimethylarsinous acid co-treated with Arsenic Trioxide] results in increased localization of SUMO1 protein CTD PMID:29774349 NCBI chr 9:66,453,428...66,483,614
Ensembl chr 9:66,453,438...66,483,614
JBrowse link
G Tagln transgelin increases expression ISO dimethylarsinous acid results in increased expression of TAGLN mRNA CTD PMID:23876855 NCBI chr 8:50,222,895...50,228,369
Ensembl chr 8:50,222,896...50,231,357
JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member increases expression ISO dimethylarsinous acid results in increased expression of TAP1 mRNA CTD PMID:20886546 NCBI chr20:3,979,302...3,989,669
Ensembl chr20:3,979,035...3,989,669
JBrowse link
G Tcf12 transcription factor 12 decreases expression ISO dimethylarsinous acid results in decreased expression of TCF12 mRNA CTD PMID:16507463 NCBI chr 8:78,343,634...78,657,738
Ensembl chr 8:78,345,754...78,655,856
JBrowse link
G Tfcp2l1 transcription factor CP2-like 1 decreases expression ISO dimethylarsinous acid results in decreased expression of TFCP2L1 mRNA CTD PMID:23876855 NCBI chr13:34,610,689...34,671,617
Ensembl chr13:34,610,684...34,670,124
JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression ISO dimethylarsinous acid results in increased expression of TGFB2 mRNA CTD PMID:19945496, PMID:20886546 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Thbs1 thrombospondin 1 decreases expression ISO dimethylarsinous acid results in decreased expression of THBS1 mRNA CTD PMID:16507463 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase increases expression ISO dimethylarsinous acid results in increased expression of TIGAR mRNA CTD PMID:20886546 NCBI chr 4:159,635,145...159,654,108
Ensembl chr 4:159,635,153...159,654,063
JBrowse link
G Tlr4 toll-like receptor 4 increases expression ISO dimethylarsinous acid results in increased expression of TLR4 mRNA CTD PMID:19945496 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tmem50b transmembrane protein 50B decreases expression ISO dimethylarsinous acid results in decreased expression of TMEM50B mRNA CTD PMID:16507463 NCBI chr11:31,719,441...31,752,276
Ensembl chr11:31,719,443...31,752,243
JBrowse link
G Tnf tumor necrosis factor increases expression
increases secretion
multiple interactions
ISO dimethylarsinous acid results in increased expression of TNF mRNA
dimethylarsinous acid results in increased secretion of TNF protein
Lipopolysaccharides inhibits the reaction [dimethylarsinous acid results in increased expression of TNF mRNA]; Lipopolysaccharides inhibits the reaction [dimethylarsinous acid results in increased secretion of TNF protein]
CTD PMID:24140498 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 increases expression ISO dimethylarsinous acid results in increased expression of TP53INP1 mRNA CTD PMID:20886546 NCBI chr 5:24,402,895...24,419,651
Ensembl chr 5:24,410,863...24,416,888
JBrowse link
G Txndc17 thioredoxin domain containing 17 decreases expression ISO dimethylarsinous acid results in decreased expression of TXNDC17 mRNA CTD PMID:16507463 NCBI chr10:58,776,792...58,779,764
Ensembl chr10:58,776,792...58,779,764
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases expression ISO dimethylarsinous acid results in increased expression of UGT1A6 mRNA CTD PMID:20886546 NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Vcan versican decreases expression ISO dimethylarsinous acid results in decreased expression of VCAN mRNA CTD PMID:23876855 NCBI chr 2:18,490,102...18,587,340
Ensembl chr 2:18,490,102...18,565,842
JBrowse link
G Vgll3 vestigial-like family member 3 increases expression ISO dimethylarsinous acid results in increased expression of VGLL3 mRNA CTD PMID:23876855 NCBI chr11:3,119,509...3,168,883
Ensembl chr11:3,119,885...3,164,751
JBrowse link
G Xaf1 XIAP associated factor 1 affects expression ISO dimethylarsinous acid affects the expression of XAF1 mRNA CTD PMID:20886546 NCBI chr10:58,860,647...58,872,782
Ensembl chr10:58,860,940...58,873,674
JBrowse link
G Zcchc2 zinc finger CCHC-type containing 2 increases expression ISO dimethylarsinous acid results in increased expression of ZCCHC2 mRNA CTD PMID:19945496 NCBI chr13:25,961,762...26,052,472
Ensembl chr13:25,966,428...26,013,338
JBrowse link
methylarsonic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression EXP monomethylarsonic acid results in increased expression of ABCB1A mRNA; monomethylarsonic acid results in increased expression of ABCB1A protein CTD PMID:16436460 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression
affects expression
EXP
ISO
monomethylarsonic acid results in increased expression of ABCC1 mRNA; monomethylarsonic acid results in increased expression of ABCC1 protein
monomethylarsonic acid affects the expression of ABCC1 mRNA
CTD PMID:16436460, PMID:24091636 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression EXP
ISO
monomethylarsonic acid results in increased expression of ABCC2 mRNA; monomethylarsonic acid results in increased expression of ABCC2 protein CTD PMID:16436460, PMID:24091636 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression EXP monomethylarsonic acid results in increased expression of ABCC3 mRNA; monomethylarsonic acid results in increased expression of ABCC3 protein CTD PMID:16436460 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Afp alpha-fetoprotein increases expression ISO monomethylarsonic acid results in increased expression of AFP mRNA CTD PMID:15345372 NCBI chr14:19,141,755...19,159,919
Ensembl chr14:19,141,755...19,159,923
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO AHR mutant form inhibits the reaction [monomethylarsonic acid results in increased expression of CYP1A1 protein]; monomethylarsonic acid results in decreased expression of and affects the localization of AHR protein CTD PMID:24161444 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of AKT1 mRNA CTD PMID:23192986 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G As3mt arsenite methyltransferase increases metabolic processing
multiple interactions
increases chemical synthesis
ISO AS3MT protein polymorphism results in increased metabolism of monomethylarsonic acid; AS3MT protein results in increased metabolism of monomethylarsonic acid
[AS3MT gene polymorphism affects the susceptibility to Arsenic] which results in increased abundance of monomethylarsonic acid; [AS3MT protein polymorphism results in increased metabolism of arsenite] which results in increased chemical synthesis of monomethylarsonic acid; [AS3MT protein polymorphism results in increased metabolism of monomethylarsonic acid] which results in increased chemical synthesis of Cacodylic Acid; [AS3MT protein polymorphism results in increased metabolism of monomethylarsonic acid] which results in increased chemical synthesis of dimethylarsinous acid; [AS3MT protein results in increased metabolism of arsenite] which results in increased chemical synthesis of monomethylarsonic acid; [AS3MT protein results in increased metabolism of monomethylarsonic acid] which results in increased chemical synthesis of Cacodylic Acid; [AS3MT protein results in increased metabolism of monomethylarsonic acid] which results in increased chemical synthesis of dimethylarsinous acid
AS3MT protein results in increased chemical synthesis of monomethylarsonic acid
CTD PMID:22005461, PMID:22868225, PMID:24845704 NCBI chr 1:266,482,787...266,514,570
Ensembl chr 1:266,482,858...266,514,569
JBrowse link
G Casp3 caspase 3 affects response to substance
multiple interactions
increases expression
EXP
ISO
CASP3 protein affects the susceptibility to monomethylarsonic acid
[sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of CASP3 mRNA
monomethylarsonic acid results in increased expression of CASP3 mRNA
[monomethylarsonic acid co-treated with Buthionine Sulfoximine] results in increased activity of CASP3 protein
CTD PMID:15963344, PMID:17481689, PMID:23192986 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cat catalase multiple interactions EXP [CAT protein results in decreased oxidation of monomethylarsonous acid] which results in decreased chemical synthesis of monomethylarsonic acid CTD PMID:18619986 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccnd1 cyclin D1 increases expression EXP monomethylarsonic acid results in increased expression of CCND1 mRNA CTD PMID:17481689 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccne1 cyclin E1 increases expression EXP monomethylarsonic acid results in increased expression of CCNE1 mRNA CTD PMID:17481689 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Cdc25b cell division cycle 25B decreases activity ISO monomethylarsonic acid results in decreased activity of CDC25B protein CTD PMID:20025242 NCBI chr 3:123,731,539...123,741,696
Ensembl chr 3:123,731,539...123,741,339
JBrowse link
G Cdh1 cadherin 1 increases expression EXP monomethylarsonic acid results in increased expression of CDH1 mRNA CTD PMID:17481689 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdh2 cadherin 2 increases expression EXP monomethylarsonic acid results in increased expression of CDH2 mRNA CTD PMID:17481689 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression
multiple interactions
EXP
ISO
monomethylarsonic acid results in decreased expression of CDKN1A mRNA
[sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of CDKN1A mRNA
CTD PMID:17481689, PMID:23192986 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO AHR mutant form inhibits the reaction [monomethylarsonic acid results in increased expression of CYP1A1 protein]; monomethylarsonic acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A1 protein]; monomethylarsonic acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; monomethylarsonic acid results in increased expression of and results in increased activity of CYP1A1 protein
monomethylarsonic acid results in increased expression of CYP1A1 mRNA
CTD PMID:24161444 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP monomethylarsonic acid results in increased expression of CYP1A2 mRNA CTD PMID:17481689 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions
increases expression
EXP [monomethylarsonic acid co-treated with Diethylnitrosamine] results in increased expression of CYP2B1 mRNA; [monomethylarsonic acid co-treated with Diethylnitrosamine] results in increased expression of CYP2B1 protein
monomethylarsonic acid results in increased expression of CYP2B1 mRNA
CTD PMID:12115560, PMID:17481689 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 multiple interactions EXP [monomethylarsonic acid co-treated with Diethylnitrosamine] results in increased expression of CYP2B2 mRNA CTD PMID:12115560 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 increases expression EXP monomethylarsonic acid results in increased expression of CYP2C11 mRNA CTD PMID:17481689 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Ddb2 damage specific DNA binding protein 2 multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of DDB2 mRNA CTD PMID:23192986 NCBI chr 3:80,030,437...80,052,984
Ensembl chr 3:80,030,437...80,052,953
JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases expression EXP monomethylarsonic acid results in decreased expression of DNMT1 mRNA CTD PMID:17481689 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Egr1 early growth response 1 increases expression
multiple interactions
ISO monomethylarsonic acid results in increased expression of EGR1 mRNA
[sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of EGR1 mRNA
CTD PMID:15345372, PMID:23192986 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of ESR1 mRNA CTD PMID:23192986 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Fancd2 FA complementation group D2 multiple interactions ISO [monomethylarsonic acid results in decreased activity of FANCD2 protein] which results in increased susceptibility to diepoxybutane; [monomethylarsonic acid results in decreased activity of FANCD2 protein] which results in increased susceptibility to Hydroxyurea; [monomethylarsonic acid results in decreased activity of FANCD2 protein] which results in increased susceptibility to Mitomycin CTD PMID:25092648 NCBI chr 4:145,489,869...145,551,479
Ensembl chr 4:145,489,869...145,551,479
JBrowse link
G Fas Fas cell surface death receptor decreases expression ISO monomethylarsonic acid results in decreased expression of FAS mRNA CTD PMID:29864498 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand increases expression EXP monomethylarsonic acid results in increased expression of FASLG mRNA CTD PMID:17481689 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fgf2 fibroblast growth factor 2 increases expression ISO monomethylarsonic acid results in increased expression of FGF2 mRNA CTD PMID:15345372 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of FKBP5 mRNA CTD PMID:23192986 NCBI chr20:7,976,704...8,097,290
Ensembl chr20:7,976,713...8,019,020
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of FOS mRNA CTD PMID:23192986 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Gjb1 gap junction protein, beta 1 increases expression EXP monomethylarsonic acid results in increased expression of GJB1 mRNA CTD PMID:17481689 NCBI chr  X:71,272,030...71,279,973
Ensembl chr  X:71,272,042...71,279,977
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression
decreases expression
ISO
EXP
monomethylarsonic acid results in increased expression of GSTA2 mRNA
monomethylarsonic acid results in decreased expression of GSTA2 mRNA; monomethylarsonic acid results in decreased expression of GSTA2 protein
CTD PMID:15345372, PMID:16436460, PMID:17481689 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gsta6 glutathione S-transferase alpha 6 increases expression ISO monomethylarsonic acid results in increased expression of GSTA2 mRNA CTD PMID:15345372 NCBI chr 9:27,475,273...27,533,939
Ensembl chr 9:27,475,273...27,511,176
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP monomethylarsonic acid results in increased expression of GSTM1 mRNA; monomethylarsonic acid results in increased expression of GSTM1 protein CTD PMID:16436460 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gsto1 glutathione S-transferase omega 1 multiple interactions
increases reduction
ISO [GSTO1 protein results in increased metabolism of monomethylarsonic acid] which results in increased chemical synthesis of monomethylarsonous acid
GSTO1 protein results in increased reduction of monomethylarsonic acid
CTD PMID:12928150, PMID:15929903 NCBI chr 1:267,607,437...267,617,387
Ensembl chr 1:267,607,418...267,617,387
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP monomethylarsonic acid results in increased expression of GSTP1 mRNA CTD PMID:17481689 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gstt1 glutathione S-transferase theta 1 affects methylation ISO GSTT1 protein affects the methylation of monomethylarsonic acid CTD PMID:17431481 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Gzma granzyme A decreases expression ISO monomethylarsonic acid results in decreased expression of GZMA mRNA CTD PMID:15345372 NCBI chr 2:44,968,846...44,981,436
Ensembl chr 2:44,968,765...44,981,458
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
decreases expression
ISO
EXP
monomethylarsonic acid results in increased expression of HMOX1 mRNA
[sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of HMOX1 mRNA
monomethylarsonic acid results in decreased expression of HMOX1 mRNA
CTD PMID:15345372, PMID:23192986, PMID:24091636 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Igf1r insulin-like growth factor 1 receptor increases expression EXP monomethylarsonic acid results in increased expression of IGF1R mRNA CTD PMID:17481689 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression ISO monomethylarsonic acid results in increased expression of IGFBP1 mRNA CTD PMID:15345372 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 increases expression EXP monomethylarsonic acid results in increased expression of ITIH3 mRNA CTD PMID:17481689 NCBI chr16:6,983,779...7,007,288
Ensembl chr16:6,992,062...7,007,287
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of JUN mRNA CTD PMID:23192986 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Krt18 keratin 18 decreases expression EXP monomethylarsonic acid results in decreased expression of KRT18 mRNA CTD PMID:17481689 NCBI chr 7:143,629,455...143,633,131
Ensembl chr 7:143,629,455...143,633,131
JBrowse link
G Lgals8 galectin 8 multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of LGALS8 mRNA CTD PMID:23192986 NCBI chr17:66,487,451...66,515,316
Ensembl chr17:66,487,457...66,511,870
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of MAPK1 mRNA CTD PMID:23192986 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression
multiple interactions
EXP
ISO
monomethylarsonic acid results in increased expression of MDM2 mRNA
[sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of MDM2 mRNA
CTD PMID:17481689, PMID:23192986 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Msh2 mutS homolog 2 decreases expression EXP monomethylarsonic acid results in decreased expression of MSH2 mRNA CTD PMID:17481689 NCBI chr 6:11,215,951...11,274,916
Ensembl chr 6:11,215,963...11,274,932
JBrowse link
G Mx2 MX dynamin like GTPase 2 multiple interactions ISO [Arsenic results in increased abundance of monomethylarsonic acid] which affects the expression of MX1 mRNA CTD PMID:28793237 NCBI chr11:38,035,306...38,066,185
Ensembl chr11:38,035,450...38,059,950
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of MYC mRNA CTD PMID:23192986 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G N6amt1 N-6 adenine-specific DNA methyltransferase 1 increases abundance ISO N6AMT1 gene polymorphism results in increased abundance of monomethylarsonic acid CTD PMID:23665909 NCBI chr11:27,004,335...27,016,690
Ensembl chr11:27,004,320...27,016,941
JBrowse link
G Nfe2l1 nuclear factor, erythroid 2-like 1 multiple interactions ISO [NFE2L1 protein alternative form results in decreased methylation of arsenite] which results in decreased abundance of monomethylarsonic acid CTD PMID:28549828 NCBI chr10:84,686,762...84,699,313
Ensembl chr10:84,682,460...84,698,886
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 decreases expression
multiple interactions
ISO monomethylarsonic acid results in decreased expression of NFE2L2 mRNA
monomethylarsonic acid results in increased expression of and affects the localization of NFE2L2 protein; NFE2L2 mutant form inhibits the reaction [monomethylarsonic acid results in increased expression of NQO1 protein]
CTD PMID:24091636, PMID:24161444 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of NFKB1 mRNA CTD PMID:23192986 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression
ISO monomethylarsonic acid promotes the reaction [sulforafan results in increased expression of and results in increased activity of NQO1 protein]; monomethylarsonic acid promotes the reaction [sulforafan results in increased expression of NQO1 mRNA]; monomethylarsonic acid promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of NQO1 protein]; monomethylarsonic acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; monomethylarsonic acid results in increased expression of and results in increased activity of NQO1 protein; NFE2L2 mutant form inhibits the reaction [monomethylarsonic acid results in increased expression of NQO1 protein]
monomethylarsonic acid results in increased expression of NQO1 mRNA
CTD PMID:24161444 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase increases expression EXP monomethylarsonic acid results in increased expression of OGG1 mRNA CTD PMID:17481689 NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326
JBrowse link
G Pcna proliferating cell nuclear antigen increases expression EXP monomethylarsonic acid results in increased expression of PCNA mRNA CTD PMID:17481689 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Prkca protein kinase C, alpha increases expression EXP monomethylarsonic acid results in increased expression of PRKCA mRNA CTD PMID:17481689 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947
JBrowse link
G Pten phosphatase and tensin homolog decreases expression ISO
EXP
monomethylarsonic acid results in decreased expression of PTEN mRNA CTD PMID:24091636 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of RAF1 mRNA CTD PMID:23192986 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of RELA mRNA CTD PMID:23192986 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases import ISO
EXP
SLC2A1 protein results in increased import of monomethylarsonic acid CTD PMID:17064664 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Sod1 superoxide dismutase 1 increases expression ISO
EXP
monomethylarsonic acid results in increased expression of SOD1 mRNA CTD PMID:24091636 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 increases expression EXP
ISO
monomethylarsonic acid results in increased expression of SOD2 mRNA CTD PMID:24091636 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of SRC mRNA CTD PMID:23192986 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of STAT3 mRNA CTD PMID:23192986 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of TGFB1 mRNA CTD PMID:23192986 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 increases expression EXP monomethylarsonic acid results in increased expression of TGFBR2 mRNA CTD PMID:17481689 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494
JBrowse link
G Thbd thrombomodulin multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of THBD mRNA CTD PMID:23192986 NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A decreases expression EXP monomethylarsonic acid results in decreased expression of TNFRSF1A mRNA CTD PMID:17481689 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of TP53 mRNA CTD PMID:23192986 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Traf3 Tnf receptor-associated factor 3 decreases expression ISO monomethylarsonic acid results in decreased expression of TRAF3 mRNA CTD PMID:15345372 NCBI chr 6:135,610,698...135,720,247
Ensembl chr 6:135,610,743...135,718,564
JBrowse link
G Txn1 thioredoxin 1 multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of TXN mRNA CTD PMID:23192986 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of TXNRD1 mRNA CTD PMID:23192986 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Wnt1 Wnt family member 1 multiple interactions ISO [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of WNT1 mRNA CTD PMID:23192986 NCBI chr 7:140,464,999...140,469,046
Ensembl chr 7:140,464,999...140,469,046
JBrowse link
phenylarsonic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gls glutaminase decreases expression
decreases activity
ISO benzenearsonic acid results in decreased expression of GLS protein
benzenearsonic acid results in decreased activity of GLS protein
CTD PMID:19428935 NCBI chr 9:54,212,622...54,284,879
Ensembl chr 9:54,212,767...54,284,872
JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP benzenearsonic acid results in increased expression of HMOX1 mRNA CTD PMID:15368090 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
roxarsone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 decreases expression ISO Roxarsone results in decreased expression of ANGPT1 mRNA CTD PMID:18414637 NCBI chr 7:81,338,327...81,592,459
Ensembl chr 7:81,342,280...81,592,206
JBrowse link
G Cnmd chondromodulin decreases expression ISO Roxarsone results in decreased expression of CNMD mRNA CTD PMID:18414637 NCBI chr15:61,923,291...61,947,840
Ensembl chr15:61,923,299...61,947,764
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 decreases expression ISO Roxarsone results in decreased expression of CXCL9 mRNA CTD PMID:18414637 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 increases secretion ISO Roxarsone results in increased secretion of ENPP2 protein CTD PMID:22952646 NCBI chr 7:94,479,931...94,563,086
Ensembl chr 7:94,480,396...94,563,001
JBrowse link
G Fhdc1 FH2 domain containing 1 decreases expression ISO Roxarsone results in decreased expression of INF1 mRNA CTD PMID:18414637 NCBI chr 2:183,450,608...183,487,820
Ensembl chr 2:183,450,619...183,487,820
JBrowse link
G Hgf hepatocyte growth factor increases expression ISO Roxarsone results in increased expression of HGF mRNA CTD PMID:18414637 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Lep leptin decreases expression ISO Roxarsone results in decreased expression of LEP mRNA CTD PMID:18414637 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression ISO Roxarsone results in increased expression of MMP9 mRNA; Roxarsone results in increased expression of MMP9 protein CTD PMID:22952646 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions ISO Roxarsone results in increased phosphorylation of and results in increased activity of NOS3 protein CTD PMID:18414637 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 increases expression
multiple interactions
ISO Roxarsone results in increased expression of PECAM1 protein
Semaxinib inhibits the reaction [Roxarsone results in increased expression of PECAM1 protein]
CTD PMID:30028964 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Plg plasminogen decreases expression ISO Roxarsone results in decreased expression of PLG mRNA CTD PMID:18414637 NCBI chr 1:48,521,828...48,563,895
Ensembl chr 1:48,521,772...48,563,776
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP Roxarsone results in increased expression of and results in increased secretion of VEGFA protein CTD PMID:24035937 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    chemical entity 19810
      atom 19808
        nonmetal atom 19683
          carbon atom 19588
            organic molecular entity 19588
              organometalloidal compound 454
                organoarsenic compound + 454
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            organometalloidal compound 454
                              organoarsenic compound + 454
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.