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ONTOLOGY REPORT - ANNOTATIONS


Term:aldrithiol
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Accession:CHEBI:143170 term browser browse the term
Definition:A member of the class of pyridines that is pyridine which is substituted by a pyridin-2-yldisulfanediyl group at position 2. It is a reagent used in molecular biology as an oxidizing agent. Also used in peptide synthesis and for detecting thiols.
Synonyms:exact_synonym: 2,2'-disulfanediyldipyridine
 related_synonym: 2,2'-dipyridyl disulfide;   2,2'-dipyridyldisulphide;   2,2'-dithiobis-pyridine;   2,2'-dithiobispyridine;   2,2'-dithiodipyridine;   2,2'-pyridine disulfide;   2-dipyridyl disulfide;   2-pyridinyl disulfide;   Formula=C10H8N2S2;   InChI=1S/C10H8N2S2/c1-3-7-11-9(5-1)13-14-10-6-2-4-8-12-10/h1-8H;   InChIKey=HAXFWIACAGNFHA-UHFFFAOYSA-N;   SMILES=S(SC=1N=CC=CC1)C=2N=CC=CC2;   aldrithiol-2;   bis(2-pyridyl)disulfide;   di(2-pyridyl)disulfide
 xref: Beilstein:154629 "Beilstein";   CAS:2127-03-9 "ChemIDplus";   CAS:2127-03-9 "NIST Chemistry WebBook"
 xref_mesh: MESH:C001105
 xref: PMID:11331359 "Europe PMC";   PMID:16998480 "Europe PMC";   PMID:17506610 "Europe PMC";   PMID:20965543 "Europe PMC";   PMID:22561701 "Europe PMC";   PMID:22807723 "Europe PMC";   PMID:23751221 "Europe PMC";   PMID:30597776 "Europe PMC";   Wikipedia:2\,2'-Dipyridyldisulfide


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aldrithiol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Nppa natriuretic peptide A JBrowse link 5 164,808,407 164,809,716 RGD:6480464
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A JBrowse link 7 51,404,971 51,515,382 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19749
    role 19696
      chemical role 19209
        oxidising agent 9120
          aldrithiol 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19749
    subatomic particle 19745
      composite particle 19745
        hadron 19745
          baryon 19745
            nucleon 19745
              atomic nucleus 19745
                atom 19745
                  main group element atom 19630
                    p-block element atom 19630
                      carbon group element atom 19523
                        carbon atom 19517
                          organic molecular entity 19517
                            organic molecule 19434
                              organic cyclic compound 19203
                                organic heterocyclic compound 18272
                                  organic heteromonocyclic compound 16357
                                    pyridines 8332
                                      aldrithiol 6
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.