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Accession:CHEBI:143514 term browser browse the term
Definition:An N-acyl-amino acid resulting from the formal condensation of the carboxy group of arachidonic acid with the amino group of L-serine. It is an endocannabinoid-like lipid isolated from bovine brains.
Synonyms:exact_synonym: N-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoyl]-L-serine
 related_synonym: (2S)-3-hydroxy-2-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenamido]propanoic acid;   (2S)-3-hydroxy-2-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoylamino]propanoic acid;   ARA-S;   Formula=C23H37NO4;   InChI=1S/C23H37NO4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(26)24-21(20-25)23(27)28/h6-7,9-10,12-13,15-16,21,25H,2-5,8,11,14,17-20H2,1H3,(H,24,26)(H,27,28)/b7-6-,10-9-,13-12-,16-15-/t21-/m0/s1;   InChIKey=FQUVPTVNRMUOPO-UPQKDGGNSA-N;   N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-serine;   N-[(5Z,8Z,11Z,14Z)-1-Oxo-5,8,11,14-icosatetraenyl]-L-serine;   SMILES=C(CCC)C/C=C\\C/C=C\\C/C=C\\C/C=C\\CCCC(N[C@H](C(=O)O)CO)=O
 xref: CAS:187224-29-9 "SUBMITTER";   LIPID_MAPS_instance:LMFA08020073 "LIPID MAPS";   PMID:16467152 "SUBMITTER";   PMID:18234973 "Europe PMC";   PMID:18923087 "Europe PMC";   PMID:20649562 "Europe PMC";   PMID:20649563 "Europe PMC";   PMID:21505478 "Europe PMC";   PMID:23695434 "Europe PMC";   PMID:28955964 "Europe PMC"

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Term Annotations click to browse term
  CHEBI ontology 19679
    role 19623
      biological role 19621
        pharmacological role 18695
          agonist 18021
            cannabinoid receptor agonist 316
              N-arachidonoyl-L-serine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19679
    subatomic particle 19675
      composite particle 19675
        hadron 19675
          baryon 19675
            nucleon 19675
              atomic nucleus 19675
                atom 19675
                  main group element atom 19555
                    p-block element atom 19555
                      carbon group element atom 19438
                        carbon atom 19430
                          organic molecular entity 19430
                            organic group 18351
                              organic divalent group 18340
                                organodiyl group 18340
                                  carbonyl group 18225
                                    carbonyl compound 18225
                                      carboxylic acid 17930
                                        monocarboxylic acid 17259
                                          fatty acid 15815
                                            unsaturated fatty acid 888
                                              polyunsaturated fatty acid 646
                                                fatty acid 20:4 309
                                                  icosatetraenoic acid 309
                                                    icosa-5,8,11,14-tetraenoic acid 260
                                                      arachidonic acid 260
                                                        N-arachidonoyl-L-serine 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.