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ONTOLOGY REPORT - ANNOTATIONS


Term:SB-245391
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Accession:CHEBI:144676 term browser browse the term
Definition:A piperidinylimidazole that is 1H-imidazole carrying a piperidin-4-yl group, 4-fluorophenyl group and a 2-([biphenyl]-4-yloxy)pyrimidin-4-yl group at positions 1, 4 and 5 respectively. It is a potent inhibitor of p38alpha mitogen-activated protein kinase.
Synonyms:exact_synonym: 2-([biphenyl]-4-yloxy)-4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl]pyrimidine
 related_synonym: 2-(4-biphenylyloxy)-4-[1-(piperidine-4-yl)-4-(4-fluorophenyl)-5-imidazolyl]pyrimidine;   2-[([1,1'-biphenyl]-4-yl)oxy]-4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl]pyrimidine;   Formula=C30H26FN5O;   InChI=1S/C30H26FN5O/c31-24-10-6-23(7-11-24)28-29(36(20-34-28)25-14-17-32-18-15-25)27-16-19-33-30(35-27)37-26-12-8-22(9-13-26)21-4-2-1-3-5-21/h1-13,16,19-20,25,32H,14-15,17-18H2;   InChIKey=WHARNYOKNQYQGR-UHFFFAOYSA-N;   SMILES=C1(=NC=CC(C2=C(C3=CC=C(F)C=C3)N=CN2C4CCNCC4)=N1)OC=5C=CC(=CC5)C=6C=CC=CC6
 xref: PMID:11354358


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  CHEBI ontology 19758
    chemical entity 19757
      molecular entity 19755
        polyatomic entity 19666
          molecule 19473
            cyclic compound 19241
              ring assembly 6896
                biphenyls 5631
                  SB-245391 0
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  CHEBI ontology 19758
    subatomic particle 19756
      composite particle 19756
        hadron 19756
          baryon 19756
            nucleon 19756
              atomic nucleus 19756
                atom 19756
                  main group element atom 19641
                    p-block element atom 19641
                      carbon group element atom 19532
                        carbon atom 19521
                          organic molecular entity 19521
                            organic molecule 19441
                              organic cyclic compound 19203
                                organic heterocyclic compound 18278
                                  heteroarene 15829
                                    monocyclic heteroarene 13144
                                      azole 12271
                                        diazole 8092
                                          imidazoles 7642
                                            piperidinylimidazole 0
                                              SB-245391 0
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