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ONTOLOGY REPORT - ANNOTATIONS


Term:SB-245391
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Accession:CHEBI:144676 term browser browse the term
Definition:A piperidinylimidazole that is 1H-imidazole carrying a piperidin-4-yl group, 4-fluorophenyl group and a 2-([biphenyl]-4-yloxy)pyrimidin-4-yl group at positions 1, 4 and 5 respectively. It is a potent inhibitor of p38alpha mitogen-activated protein kinase.
Synonyms:exact_synonym: 2-([biphenyl]-4-yloxy)-4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl]pyrimidine
 related_synonym: 2-(4-biphenylyloxy)-4-[1-(piperidine-4-yl)-4-(4-fluorophenyl)-5-imidazolyl]pyrimidine;   2-[([1,1'-biphenyl]-4-yl)oxy]-4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl]pyrimidine;   Formula=C30H26FN5O;   InChI=1S/C30H26FN5O/c31-24-10-6-23(7-11-24)28-29(36(20-34-28)25-14-17-32-18-15-25)27-16-19-33-30(35-27)37-26-12-8-22(9-13-26)21-4-2-1-3-5-21/h1-13,16,19-20,25,32H,14-15,17-18H2;   InChIKey=WHARNYOKNQYQGR-UHFFFAOYSA-N;   SMILES=C1(=NC=CC(C2=C(C3=CC=C(F)C=C3)N=CN2C4CCNCC4)=N1)OC=5C=CC(=CC5)C=6C=CC=CC6
 xref: PMID:11354358


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  CHEBI ontology 23909
    chemical entity 23872
      molecular entity 23821
        polyatomic entity 23730
          molecule 23232
            cyclic compound 22249
              ring assembly 7157
                biphenyls 5805
                  SB-245391 0
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  CHEBI ontology 23909
    subatomic particle 23860
      composite particle 23860
        hadron 23860
          baryon 23860
            nucleon 23860
              atomic nucleus 23860
                atom 23860
                  main group element atom 23681
                    p-block element atom 23681
                      carbon group element atom 23401
                        carbon atom 23358
                          organic molecular entity 23358
                            organic molecule 23222
                              organic cyclic compound 22248
                                organic heterocyclic compound 20780
                                  heteroarene 17182
                                    monocyclic heteroarene 14289
                                      azole 13549
                                        diazole 8908
                                          imidazoles 8195
                                            piperidinylimidazole 0
                                              SB-245391 0
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