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Accession:CHEBI:144677 term browser browse the term
Definition:A piperidinylimidazole that is 1H-imidazole carrying a piperidin-4-yl group, 4-fluorophenyl group and a 2-(3,5-dimethylphenoxy)pyrimidin-4-yl group at positions 1, 4 and 5 respectively. It is a potent inhibitor of p38alpha mitogen-activated protein kinase and BRD4.
Synonyms:exact_synonym: 2-(3,5-dimethylphenoxy)-4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl]pyrimidine
 related_synonym: 2-(3,5-dimethylphenoxy)-4-[4-(4-fluorophenyl)-1-(4-piperidinyl)-1H-imidazol-5-yl]pyrimidine;   Formula=C26H26FN5O;   InChI=1S/C26H26FN5O/c1-17-13-18(2)15-22(14-17)33-26-29-12-9-23(31-26)25-24(19-3-5-20(27)6-4-19)30-16-32(25)21-7-10-28-11-8-21/h3-6,9,12-16,21,28H,7-8,10-11H2,1-2H3;   InChIKey=UVLWMBRFRAMDOW-UHFFFAOYSA-N;   SB-284851;   SB284851BT;   SMILES=CC1=CC(C)=CC(OC2=NC=CC(C3=C(C4=CC=C(F)C=C4)N=CN3C5CCNCC5)=N2)=C1
 xref: PMID:11354358;   PMID:26158404

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  CHEBI ontology 19758
    role 19705
      biological role 19704
        inhibitor 18174
          bromodomain-containing protein 4 inhibitor 0
            SB-284851-BT 0
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  CHEBI ontology 19758
    subatomic particle 19756
      composite particle 19756
        hadron 19756
          baryon 19756
            nucleon 19756
              atomic nucleus 19756
                atom 19756
                  main group element atom 19641
                    p-block element atom 19641
                      carbon group element atom 19532
                        carbon atom 19521
                          organic molecular entity 19521
                            organic molecule 19441
                              organic cyclic compound 19203
                                organic heterocyclic compound 18278
                                  heteroarene 15829
                                    monocyclic heteroarene 13144
                                      azole 12271
                                        diazole 8092
                                          imidazoles 7642
                                            piperidinylimidazole 0
                                              SB-284851-BT 0
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