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ONTOLOGY REPORT - ANNOTATIONS


Term:12-hydroxynevirapine
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Accession:CHEBI:145206 term browser browse the term
Definition:A dipyridodiazepine that is nevirapine in which one of the hydrogens of the methyl group has been substituted by a hydroxy group. It is a metabolite of the anti-HIV drug, nevirapine.
Synonyms:exact_synonym: 11-cyclopropyl-4-(hydroxymethyl)-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
 related_synonym: 11-cyclopropyl-4-(hydroxymethyl)-5H-dipyrido[2,3-e:2',3'-f][1,4]diazepin-6-one;   12-OH-NVP;   12-hydroxy-NVP;   12-hydroxy-nevirapine;   Formula=C15H14N4O2;   InChI=1S/C15H14N4O2/c20-8-9-5-7-17-14-12(9)18-15(21)11-2-1-6-16-13(11)19(14)10-3-4-10/h1-2,5-7,10,20H,3-4,8H2,(H,18,21);   InChIKey=SEBABOMFNCVZGF-UHFFFAOYSA-N;   N(11)-cyclopropyl-4-hydroxymethyl-5,11-dihydro-6H-dipyrido(3,2-b:2,3-e)(1,4)diazepin-6-one;   SMILES=O=C1NC=2C(N(C3CC3)C=4N=CC=CC41)=NC=CC2CO
 xref: CAS:133627-24-4 "ChemIDplus";   HMDB:HMDB0013911;   PMID:10421616 "Europe PMC";   PMID:17618842 "Europe PMC";   PMID:18042504 "Europe PMC";   PMID:18597499 "Europe PMC";   PMID:20392079 "Europe PMC";   PMID:23459477 "Europe PMC";   PMID:23590230 "Europe PMC";   PMID:23947594 "Europe PMC";   PMID:24051761 "Europe PMC";   PMID:25275777 "Europe PMC";   PMID:25394082 "Europe PMC";   PMID:26620700 "Europe PMC";   PMID:29309900 "Europe PMC";   PMID:30028994 "Europe PMC"


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  CHEBI ontology 19734
    role 19680
      biological role 19678
        antimicrobial agent 17216
          antiviral agent 3710
            antiviral drug 1777
              nevirapine 123
                12-hydroxynevirapine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19734
    subatomic particle 19730
      composite particle 19730
        hadron 19730
          baryon 19730
            nucleon 19730
              atomic nucleus 19730
                atom 19730
                  main group element atom 19614
                    p-block element atom 19614
                      carbon group element atom 19506
                        carbon atom 19500
                          organic molecular entity 19500
                            organic molecule 19418
                              organic cyclic compound 19189
                                organic heterocyclic compound 18267
                                  organic heteropolycyclic compound 17572
                                    organic heterotricyclic compound 13735
                                      dipyridodiazepine 123
                                        nevirapine 123
                                          12-hydroxynevirapine 0
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