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ONTOLOGY REPORT - ANNOTATIONS


Term:4-hydroxymidazolam beta-D-glucuronide
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Accession:CHEBI:145335 term browser browse the term
Definition:A beta-D-glucosiduronic acid that is beta-D-glucuronic acid in which the anomeric hydroxyl hydrogen has been replaced by a 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepin-4-yl group. It is the glucuronidated conjugate of the midazolam metabolite, 4-hydroxymidazolam.
Synonyms:exact_synonym: 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepin-4-yl beta-D-glucopyranosiduronic acid
 related_synonym: 4-OH MDZ glucuronide;   4-hydroxymidazolam glucuronide;   Formula=C24H21ClFN3O7;   InChI=1S/C24H21ClFN3O7/c1-10-27-9-16-22(36-24-20(32)18(30)19(31)21(35-24)23(33)34)28-17(12-4-2-3-5-14(12)26)13-8-11(25)6-7-15(13)29(10)16/h2-9,18-22,24,30-32H,1H3,(H,33,34)/t18-,19-,20+,21-,22?,24-/m0/s1;   InChIKey=MPHAZAPYEZYBRV-UOPHVPOOSA-N;   SMILES=C1(=NC(C=2N(C=3C1=CC(=CC3)Cl)C(=NC2)C)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C(O)=O)O)O)O)C=5C=CC=CC5F
 xref: CAS:81256-82-8 "ChEBI";   PMID:20713656 "Europe PMC";   PMID:28978489 "Europe PMC"


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  CHEBI ontology 19745
    role 19692
      biological role 19690
        biochemical role 19188
          apoptosis inducer 10834
            midazolam 27
              4-hydroxymidazolam 1
                4-hydroxymidazolam beta-D-glucuronide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19745
    subatomic particle 19741
      composite particle 19741
        hadron 19741
          baryon 19741
            nucleon 19741
              atomic nucleus 19741
                atom 19741
                  main group element atom 19625
                    p-block element atom 19625
                      carbon group element atom 19519
                        carbon atom 19513
                          organic molecular entity 19513
                            heteroorganic entity 19077
                              organochalcogen compound 18793
                                organooxygen compound 18705
                                  carbohydrates and carbohydrate derivatives 12107
                                    carbohydrate 12107
                                      carbohydrate derivative 11730
                                        glycosyl compound 10787
                                          glycoside 9136
                                            glycosiduronic acid 129
                                              glucosiduronic acid 129
                                                beta-D-glucosiduronic acid 40
                                                  4-hydroxymidazolam beta-D-glucuronide 0
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