Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:pibutidine
go back to main search page
Accession:CHEBI:145662 term browser browse the term
Definition:An aromtic ether that is 4-(piperidin-1-ylmethyl)pyridin-2-ol in which the hydroxy group has been substituted by a {(2Z)-4-[(2-amino-3,4-dioxocyclobut-1-en-1-yl)amino]but-2-en-1-yl}oxy group. It is a H2 receptor antagonist which was developed for the treatment of peptic ulcers and duodenal ulcers.
Synonyms:exact_synonym: 3-amino-4-{[(2Z)-4-{[4-(piperidin-1-ylmethyl)pyridin-2-yl]oxy}but-2-en-1-yl]amino}cyclobut-3-ene-1,2-dione
 related_synonym: 3-amino-4-[[(Z)-4-[4-(piperidinomethyl)pyridin-2-yloxy]-2-butenyl]amino]-3-cyclobutene-1,2-dione;   Formula=C19H24N4O3;   InChI=1S/C19H24N4O3/c20-16-17(19(25)18(16)24)22-7-2-5-11-26-15-12-14(6-8-21-15)13-23-9-3-1-4-10-23/h2,5-6,8,12,22H,1,3-4,7,9-11,13,20H2/b5-2-;   InChIKey=XMDYZASWLGWIPL-DJWKRKHSSA-N;   SMILES=C1CCN(CC1)CC2=CC(=NC=C2)OC/C=C\\CNC=3C(C(C3N)=O)=O;   pibutidina;   pibutidinum
 xref: CAS:103922-33-4 "ChemIDplus";   HMDB:HMDB0041986;   PMID:10028383 "Europe PMC";   PMID:10421905 "Europe PMC";   PMID:10821404 "Europe PMC";   PMID:11130203 "Europe PMC";   PMID:11816008 "Europe PMC"
 cyclic_relationship: is_conjugate_base_of CHEBI:145665


show annotations for term's descendants       view all columns           Sort by:
 

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19754
    role 19701
      application 19353
        pharmaceutical 19222
          drug 19222
            anti-ulcer drug 752
              pibutidine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19754
    subatomic particle 19752
      composite particle 19752
        hadron 19752
          baryon 19752
            nucleon 19752
              atomic nucleus 19752
                atom 19752
                  main group element atom 19637
                    p-block element atom 19637
                      carbon group element atom 19528
                        carbon atom 19517
                          organic molecular entity 19517
                            organic group 18422
                              organic divalent group 18414
                                organodiyl group 18414
                                  carbonyl group 18303
                                    carbonyl compound 18303
                                      ketone 15927
                                        cyclic ketone 13368
                                          alicyclic ketone 1048
                                            cyclobutenones 0
                                              pibutidine 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.