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ONTOLOGY REPORT - ANNOTATIONS


Term:dinophysistoxin 2
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Accession:CHEBI:145981 term browser browse the term
Definition:A ketal that is a rare marine toxin structurally related to okadaic acid. Found yearly along with okadaic acid in Portuguese shellfish, its presence has been correlated with the occurrence of Dinophysis acta.
Synonyms:exact_synonym: (2R)-3-[(2S,5R,6R,8S)-8-{(2R,3E)-4-[(2R,4'aR,5R,6'S,8'R,8'aS)-8'-hydroxy-6'-{(1S,3S)-1-hydroxy-3-[(2S,6R,11R)-11-methyl-1,7-dioxaspiro[5.5]undecan-2-yl]butyl}-7'-methylidenehexahydro-3'H-spiro[oxolane-2,2'-pyrano[3,2-b]pyran]-5-yl]but-3-en-2-yl}-5-hydroxy-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl]-2-hydroxy-2-methylpropanoic acid
 related_synonym: (2R)-2-hydroxy-3-[(2S,5R,6R,8S)-5-hydroxy-8-{(2R,3E)-4-[(2R,4a'R,5R,6'S,8'R,8a'S)-8'-hydroxy-6'-{(1S,3S)-1-hydroxy-3-[(2S,6R,11R)-11-methyl-1,7-dioxaspiro[5.5]undecan-2-yl]butyl}-7'-methyleneoctahydro-3H,3'H-spiro[furan-2,2'-pyrano[3,2-b]pyran]-5-yl]but-3-en-2-yl}-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl]-2-methylpropanoic acid;   DTX-2;   DTX2;   Formula=C44H68O13;   InChI=1S/C44H68O13/c1-25-21-35(56-44(23-25)36(46)14-13-31(54-44)24-41(6,50)40(48)49)26(2)11-12-30-15-18-42(53-30)19-16-34-39(57-42)37(47)29(5)38(52-34)32(45)22-27(3)33-10-7-17-43(55-33)28(4)9-8-20-51-43/h11-12,23,26-28,30-39,45-47,50H,5,7-10,13-22,24H2,1-4,6H3,(H,48,49)/b12-11+/t26-,27+,28-,30+,31+,32+,33+,34-,35+,36-,37-,38+,39-,41-,42-,43-,44-/m1/s1;   InChIKey=BRFKTXCAUCYQBT-KIXJXINUSA-N;   SMILES=[C@@]12(O[C@]3([C@H](O)C(=C)[C@@H]([C@@H](O)C[C@@H]([C@]4(O[C@]5(OCCC[C@H]5C)CCC4)[H])C)O[C@@H]3CC1)[H])O[C@H](CC2)\\C=C\\[C@H]([C@]6(O[C@]7(O[C@H](C[C@](C(=O)O)(O)C)CC[C@H]7O)C=C(C)C6)[H])C
 xref: CAS:139933-46-3
 xref_mesh: MESH:C076221
 xref: PMID:10400295;   PMID:10775759;   PMID:15141105;   PMID:17092529;   PMID:17286044;   PMID:18226903;   PMID:18342356;   PMID:19481560;   PMID:19916524;   PMID:22285596;   PMID:23406170;   PMID:25238672;   PMID:28089692;   PMID:28223118;   PMID:30176657


show annotations for term's descendants       view all columns           Sort by:
 
dinophysistoxin 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccna1 cyclin A1 JBrowse link 2 144,456,689 144,503,570 RGD:6480464
G Ccnb2 cyclin B2 JBrowse link 8 76,847,972 76,861,165 RGD:6480464
G Cdk2 cyclin dependent kinase 2 JBrowse link 7 3,124,953 3,132,533 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19764
    role 19710
      biological role 19709
        poison 17964
          toxin 13841
            dinophysistoxin 2 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19764
    subatomic particle 19762
      composite particle 19762
        hadron 19762
          baryon 19762
            nucleon 19762
              atomic nucleus 19762
                atom 19762
                  main group element atom 19645
                    p-block element atom 19645
                      carbon group element atom 19539
                        carbon atom 19528
                          organic molecular entity 19528
                            heteroorganic entity 19106
                              organochalcogen compound 18805
                                organooxygen compound 18717
                                  ether 15856
                                    cyclic ether 6509
                                      polycyclic ether 1306
                                        okadaic acid 449
                                          dinophysistoxin 2 4
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