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ONTOLOGY REPORT - ANNOTATIONS


Term:acetylcholine
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Accession:CHEBI:15355 term browser browse the term
Definition:Actylcholine is an ester of acetic acid and choline, which acts as a neurotransmitter.
Synonyms:related_synonym: 2-(acetyloxy)-N,N,N-trimethylethanaminium;   ACh;   Azetylcholin;   Formula=C7H16NO2;   InChI=1S/C7H16NO2/c1-7(9)10-6-5-8(2,3)4/h5-6H2,1-4H3/q+1;   InChIKey=OIPILFWXSMYKGL-UHFFFAOYSA-N;   O-Acetylcholine;   SMILES=CC(=O)OCC[N+](C)(C)C;   choline acetate
 alt_id: CHEBI:12686;   CHEBI:13715;   CHEBI:22197;   CHEBI:2416;   CHEBI:40559
 xref: Beilstein:1764436 "ChemIDplus";   CAS:51-84-3 "ChemIDplus";   CAS:51-84-3 "KEGG COMPOUND";   DrugBank:DB03128;   Drug_Central:65 "DrugCentral";   Gmelin:326108 "Gmelin";   KEGG:C01996;   LINCS:LSM-5888
 xref_mesh: MESH:D000109
 xref: PDBeChem:ACH;   PMID:14764638 "Europe PMC";   PMID:15014918 "Europe PMC";   PMID:15231705 "Europe PMC";   PMID:15361288 "Europe PMC";   PMID:18050502 "Europe PMC";   PMID:18407448 "Europe PMC";   PMID:19255787 "Europe PMC";   PMID:20963497 "Europe PMC";   PMID:21130809 "Europe PMC";   PMID:21246223 "Europe PMC";   PMID:21545631 "Europe PMC";   PMID:21601579 "Europe PMC";   Wikipedia:Acetylcholine


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acetylcholine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc8 ATP binding cassette subfamily C member 8 JBrowse link 1 102,110,708 102,191,287 RGD:6480464
G Ache acetylcholinesterase JBrowse link 12 22,472,358 22,477,052 RGD:6480464
G Adcy5 adenylate cyclase 5 JBrowse link 11 68,695,839 68,842,452 RGD:6480464
G Adora2a adenosine A2a receptor JBrowse link 20 14,265,251 14,282,873 RGD:6480464
G Adra2b adrenoceptor alpha 2B JBrowse link 3 119,805,941 119,809,987 RGD:6480464
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:6480464
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:6480464
G Alox15 arachidonate 15-lipoxygenase JBrowse link 10 56,953,692 56,962,145 RGD:6480464
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:6480464
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:6480464
G Ass1 argininosuccinate synthase 1 JBrowse link 3 10,327,411 10,375,847 RGD:6480464
G Atox1 antioxidant 1 copper chaperone JBrowse link 10 40,790,850 40,805,886 RGD:6480464
G Atp7a ATPase copper transporting alpha JBrowse link X 77,076,085 77,193,644 RGD:6480464
G Bche butyrylcholinesterase JBrowse link 2 171,104,476 171,196,186 RGD:6480464
G Calca calcitonin-related polypeptide alpha JBrowse link 1 184,184,018 184,188,922 RGD:6480464
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:6480464
G Chrm1 cholinergic receptor, muscarinic 1 JBrowse link 1 224,869,087 224,885,101 RGD:6480464
G Chrm2 cholinergic receptor, muscarinic 2 JBrowse link 4 64,089,028 64,091,090 RGD:6480464
G Chrm3 cholinergic receptor, muscarinic 3 JBrowse link 17 63,990,599 64,463,222 RGD:6480464
G Chrm4 cholinergic receptor, muscarinic 4 JBrowse link 3 80,833,272 80,841,165 RGD:6480464
G Chrm5 cholinergic receptor, muscarinic 5 JBrowse link 3 103,966,451 104,018,815 RGD:6480464
G Chrna1 cholinergic receptor nicotinic alpha 1 subunit JBrowse link 3 60,445,657 60,460,724 RGD:6480464
G Chrna10 cholinergic receptor nicotinic alpha 10 subunit JBrowse link 1 167,206,722 167,212,199 RGD:6480464
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit JBrowse link 15 42,808,897 42,825,179 RGD:6480464
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit JBrowse link 8 59,594,007 59,607,122 RGD:6480464
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit JBrowse link 3 176,533,182 176,547,965 RGD:6480464
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit JBrowse link 1 123,897,341 124,039,263 RGD:6480464
G Chrna9 cholinergic receptor nicotinic alpha 9 subunit JBrowse link 14 43,883,450 43,890,171 RGD:6480464
G Chrnb1 cholinergic receptor nicotinic beta 1 subunit JBrowse link 10 56,390,671 56,403,255 RGD:6480464
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit JBrowse link 2 189,088,570 189,096,785 RGD:6480464
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit JBrowse link 8 59,610,489 59,629,073 RGD:6480464
G Chrnd cholinergic receptor nicotinic delta subunit JBrowse link 9 94,286,550 94,294,968 RGD:6480464
G Chrne cholinergic receptor nicotinic epsilon subunit JBrowse link 10 57,238,960 57,246,750 RGD:6480464
G Chrng cholinergic receptor nicotinic gamma subunit JBrowse link 9 94,302,218 94,308,591 RGD:6480464
G Crh corticotropin releasing hormone JBrowse link 2 104,459,999 104,461,863 RGD:6480464
G Csf2 colony stimulating factor 2 JBrowse link 10 39,602,089 39,604,070 RGD:6480464
G Cybb cytochrome b-245 beta chain JBrowse link X 14,578,330 14,610,049 RGD:6480464
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:6480464
G Epo erythropoietin JBrowse link 12 22,274,828 22,278,268 RGD:6480464
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:6480464
G Fbn1 fibrillin 1 JBrowse link 3 117,569,708 117,766,160 RGD:6480464
G Fkbp1b FKBP prolyl isomerase 1B JBrowse link 6 29,975,863 29,987,252 RGD:6480464
G Gch1 GTP cyclohydrolase 1 JBrowse link 15 23,935,011 23,968,971 RGD:6480464
G Gclc glutamate-cysteine ligase, catalytic subunit JBrowse link 8 85,059,051 85,097,471 RGD:6480464
G Gclm glutamate cysteine ligase, modifier subunit JBrowse link 2 225,827,504 225,847,876 RGD:6480464
G Gpx1 glutathione peroxidase 1 JBrowse link 8 117,117,430 117,118,528 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:6480464
G Il5 interleukin 5 JBrowse link 10 39,066,716 39,069,587 RGD:6480464
G Il5ra interleukin 5 receptor subunit alpha JBrowse link 4 138,796,165 138,834,164 RGD:6480464
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 JBrowse link 8 33,435,493 33,463,410 RGD:6480464
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 JBrowse link 4 176,783,287 176,789,143 RGD:6480464
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 JBrowse link 15 344,204 1,048,849 RGD:6480464
G Lepr leptin receptor JBrowse link 5 120,503,475 120,682,281 RGD:6480464
G Lpl lipoprotein lipase JBrowse link 16 22,537,687 22,561,487 RGD:6480464
G Lynx1 Ly6/neurotoxin 1 JBrowse link 7 115,982,877 115,988,121 RGD:6480464
G Lypd1 Ly6/Plaur domain containing 1 JBrowse link 13 42,219,884 42,263,024 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:6480464
G Ncf1 neutrophil cytosolic factor 1 JBrowse link 12 25,497,104 25,506,300 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:6480464
G Pkd1 polycystin 1, transient receptor potential channel interacting JBrowse link 10 13,914,057 13,962,008 RGD:6480464
G Pomc proopiomelanocortin JBrowse link 6 28,382,937 28,388,771 RGD:6480464
G Ppp1r14a protein phosphatase 1, regulatory (inhibitor) subunit 14A JBrowse link 1 87,224,683 87,232,842 RGD:6480464
G Rhoa ras homolog family member A JBrowse link 8 117,082,440 117,116,244 RGD:6480464
G Sigmar1 sigma non-opioid intracellular receptor 1 JBrowse link 5 58,121,824 58,124,687 RGD:6480464
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:6480464
G Slc17a8 solute carrier family 17 member 8 JBrowse link 7 30,215,231 30,274,993 RGD:6480464
G Slurp1 secreted Ly6/Plaur domain containing 1 JBrowse link 7 115,961,655 115,963,071 RGD:6480464
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:6480464
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:6480464
G Tac1 tachykinin, precursor 1 JBrowse link 4 33,638,853 33,646,819 RGD:6480464
G Th tyrosine hydroxylase JBrowse link 1 216,073,034 216,080,287 RGD:6480464
G Thrb thyroid hormone receptor beta JBrowse link 15 8,890,578 9,239,815 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 JBrowse link 8 6,811,543 6,917,534 RGD:6480464
G Vim vimentin JBrowse link 17 80,882,715 80,891,200 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19662
    role 19606
      biological role 19604
        molecular messenger 17946
          hormone 17752
            acetylcholine 78
              acetylcholine bromide 0
              acetylcholine chloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19662
    subatomic particle 19658
      composite particle 19658
        hadron 19658
          baryon 19658
            nucleon 19658
              atomic nucleus 19658
                atom 19658
                  main group element atom 19539
                    p-block element atom 19539
                      carbon group element atom 19422
                        carbon atom 19414
                          organic molecular entity 19414
                            organic group 18340
                              organic divalent group 18330
                                organodiyl group 18330
                                  carbonyl group 18217
                                    carbonyl compound 18217
                                      carboxylic acid 17921
                                        monocarboxylic acid 17256
                                          acetic acid 10587
                                            acetate ester 3176
                                              acetylcholine 78
                                                acetylcholine bromide 0
                                                acetylcholine chloride 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.