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ONTOLOGY REPORT - ANNOTATIONS


Term:acetic acid
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Accession:CHEBI:15366 term browser browse the term
Definition:A simple monocarboxylic acid containing two carbons.
Synonyms:related_synonym: AcOH;   CH3-COOH;   CH3CO2H;   E-260;   E260;   Essigsaeure;   Ethanoic acid;   Ethylic acid;   Formula=C2H4O2;   HOAc;   INS No. 260;   InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4);   InChIKey=QTBSBXVTEAMEQO-UHFFFAOYSA-N;   MeCO2H;   MeCOOH;   Methanecarboxylic acid;   SMILES=CC(O)=O;   acide acetique;   ethoic acid
 alt_id: CHEBI:22169;   CHEBI:2387;   CHEBI:40486
 xref: Beilstein:506007 "Beilstein";   CAS:64-19-7 "ChemIDplus";   CAS:64-19-7 "KEGG COMPOUND";   CAS:64-19-7 "NIST Chemistry WebBook";   Drug_Central:4211 "DrugCentral";   Gmelin:1380 "Gmelin";   HMDB:HMDB0000042;   KEGG:C00033;   KEGG:D00010;   KNApSAcK:C00001176;   LIPID_MAPS_instance:LMFA01010002 "LIPID MAPS"
 xref_mesh: MESH:D019342
 xref: MetaCyc:ACET;   PDBeChem:ACT;   PDBeChem:ACY;   PMID:12005138 "Europe PMC";   PMID:15107950 "Europe PMC";   PMID:16630552 "Europe PMC";   PMID:16774200 "Europe PMC";   PMID:17190852 "Europe PMC";   PMID:19416101 "Europe PMC";   PMID:19469536 "Europe PMC";   PMID:22153255 "Europe PMC";   PMID:22173419 "Europe PMC";   PPDB:1333;   Reaxys:506007 "Reaxys";   Wikipedia:Acetic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:30089


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acetylsalicylic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HSPA5 heat shock protein family A (Hsp70) member 5 JBrowse link 1 265,930,044 265,934,959 RGD:6480464
G PLA2G1B phospholipase A2 group IB JBrowse link 14 40,314,520 40,322,315 RGD:6480464
G PTGS2 prostaglandin-endoperoxide synthase 2 JBrowse link 9 127,850,164 127,858,866 RGD:6480464
alachlor term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CYP2C49 cytochrome P450 2C49 JBrowse link 14 106,571,803 106,612,082 RGD:6480464
aspartame term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ENPEP glutamyl aminopeptidase JBrowse link 8 111,765,839 111,858,349 RGD:6480464
indometacin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGT angiotensinogen JBrowse link 14 59,643,030 59,656,835 RGD:6480464
G DDIT3 DNA damage inducible transcript 3 JBrowse link 5 22,785,441 22,789,867 RGD:6480464
G HSPA5 heat shock protein family A (Hsp70) member 5 JBrowse link 1 265,930,044 265,934,959 RGD:6480464
N-acetyl-L-cysteine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BAX BCL2 associated X, apoptosis regulator JBrowse link 6 54,222,341 54,228,150 RGD:6480464
G BCL2 BCL2 apoptosis regulator JBrowse link 1 158,337,403 158,518,214 RGD:6480464
G BMP15 bone morphogenetic protein 15 JBrowse link X 44,613,122 44,620,575 RGD:6480464
G CASP3 caspase 3 JBrowse link 15 45,744,320 45,753,252 RGD:6480464
G CASP9 caspase 9 JBrowse link 6 74,707,597 74,730,033 RGD:6480464
G CCL2 chemokine (C-C motif) ligand 2 JBrowse link 12 40,798,109 40,800,013 RGD:6480464
G CYCS cytochrome c, somatic JBrowse link 18 47,169,921 47,172,212 RGD:6480464
G DDIT3 DNA damage inducible transcript 3 JBrowse link 5 22,785,441 22,789,867 RGD:6480464
G FOS Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 7 98,449,508 98,451,971 RGD:6480464
G GSR glutathione-disulfide reductase JBrowse link 15 54,382,564 54,433,989 RGD:6480464
G HSP90B1 heat shock protein 90 beta family member 1 JBrowse link 5 80,511,513 80,531,016 RGD:6480464
G HSPA5 heat shock protein family A (Hsp70) member 5 JBrowse link 1 265,930,044 265,934,959 RGD:6480464
G MAPK8 mitogen-activated protein kinase 8 JBrowse link 14 88,988,914 89,108,875 RGD:6480464
G MAPK9 mitogen-activated protein kinase 9 JBrowse link 2 78,338,466 78,399,108 RGD:6480464
G MYC MYC proto-oncogene, bHLH transcription factor JBrowse link 4 12,455,141 12,460,360 RGD:6480464
G NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 15 82,967,485 83,146,185 RGD:6480464
G PTX3 pentraxin 3 JBrowse link 13 97,273,594 97,279,570 RGD:6480464
G TNFAIP6 TNF alpha induced protein 6 JBrowse link 15 862,013 881,352 RGD:6480464
G TP53 tumor protein p53 JBrowse link 12 52,939,643 52,953,786 RGD:6480464
G ZP3 zona pellucida glycoprotein 3 JBrowse link 3 9,934,760 9,944,924 RGD:6480464
O-acetyl-L-carnitine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SLC22A5 solute carrier family 22 member 5 JBrowse link 2 134,660,741 134,847,575 RGD:6480464
phorbol 13-acetate 12-myristate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CXCL8 C-X-C motif chemokine ligand 8 JBrowse link 8 69,932,646 69,935,861 RGD:6480464
G EDN1 endothelin 1 JBrowse link 7 8,752,018 8,758,354 RGD:6480464
G MAPK1 mitogen-activated protein kinase 1 JBrowse link 14 50,083,079 50,165,528 RGD:6480464
G MAPK3 mitogen-activated protein kinase 3 JBrowse link 3 18,291,444 18,299,410 RGD:6480464
G MAPK9 mitogen-activated protein kinase 9 JBrowse link 2 78,338,466 78,399,108 RGD:6480464
G PPARA peroxisome proliferator activated receptor alpha JBrowse link 5 3,302,755 3,321,091 RGD:6480464
G PRKCB protein kinase C beta JBrowse link 3 21,995,227 22,383,628 RGD:6480464
G PRKCD protein kinase C delta JBrowse link 13 35,290,835 35,323,245 RGD:6480464
G SELE selectin E JBrowse link 4 81,289,061 81,299,657 RGD:6480464
G SELP selectin P JBrowse link 4 81,376,804 81,401,240 RGD:6480464
G VCAM1 vascular cell adhesion molecule 1 JBrowse link 4 117,496,914 117,511,211 RGD:6480464
sulindac term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PLA2G1B phospholipase A2 group IB JBrowse link 14 40,314,520 40,322,315 RGD:6480464
G PTGS2 prostaglandin-endoperoxide synthase 2 JBrowse link 9 127,850,164 127,858,866 RGD:6480464
troleandomycin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CYP3A29 cytochrome P450 3A29 JBrowse link 3 6,738,502 6,778,121 RGD:6480464
wortmannin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKT1 AKT serine/threonine kinase 1 RGD:6480464
G HIF1A hypoxia inducible factor 1 subunit alpha JBrowse link 1 190,625,436 190,673,926 RGD:6480464
G NOS3 nitric oxide synthase 3 JBrowse link 18 6,209,218 6,228,912 RGD:6480464
G TNF tumor necrosis factor JBrowse link 7 23,699,635 23,702,393 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 828
    role 805
      application 436
        food additive 81
          food acidity regulator 41
            acetic acid 41
              (1-hydroxycyclohexyl)acetic acid + 0
              (2,2,2-trifluoroethoxy)acetic acid + 0
              (2,2,3-trimethyl-5-oxocyclopent-3-en-1-yl)acetic acid + 0
              (2,6-dihydroxyphenyl)acetic acid 0
              (2-hydroxyphenyl)acetic acid 0
              (2S)-(\{(5Z)-5-[(5-ethylfuran-2-yl)methylidene]-4-oxo-4,5-dihydro-1,3-thiazol-2-yl\}amino)(4-fluorophenyl)acetic acid 0
              (2S)-[(2S,3S,4S,5S)-1,3,4,5-tetrahydroxy-4-(hydroxymethyl)piperidin-2-yl](L-tyrosylamino)acetic acid + 0
              (3-\{(1R)-3-(3,4-dimethoxyphenyl)-1-[(\{(2S)-1-[(2S)-2-(3,4,5-trimethoxyphenyl)butanoyl]piperidin-2-yl\}carbonyl)oxy]propyl\}phenoxy)acetic acid 0
              (3-amino-2,5-dioxopyrrolidin-1-yl)acetic acid 0
              (3-chloro-4-hydroxyphenyl)acetic acid 0
              (3Z)-hex-3-en-1-yl acetate 0
              (4-oxo-3-\{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl\}-3,4-dihydrophthalazin-1-yl)acetic acid 0
              (5-fluoro-2-\{[(4,5,7-trifluoro-1,3-benzothiazol-2-yl)methyl]carbamoyl\}phenoxy)acetic acid 0
              1-O-palmityl-2-acetyl-sn-glycerol + 0
              1-alkyl-2-acetylglycerol + 0
              1-hexadecyl-2-acetyl-sn-glycero-3-phosphoethanolamine 0
              1-methyl-4-imidazoleacetic acid 0
              1-palmitoyl-2-acetyl-sn-glycero-3-phosphocholine 0
              1-palmityl-2-acetyl-sn-glycero-3-phosphate 0
              1-stearoyl-2-acetyl-sn-glycero-3-phosphocholine 0
              2-acetyl-sn-glycero-3-phosphocholine 0
              2-thienylacetic acid + 0
              2H-imidazol-4-ylacetic acid 0
              3-hydroxyphenylacetic acid 0
              3-methylphenylacetic acid 0
              4-chlorophenylacetic acid 0
              4-hydroxyphenylacetic acid + 0
              6-\{[1-(benzylsulfonyl)piperidin-4-yl]amino\}-3-(carboxymethoxy)thieno[3,2-b][1]benzothiophene-2-carboxylic acid 0
              N-acetyl-amino acid + 20
              N-phenylacetamide + 1
              O-acetylcarnitine + 1
              [(1S)-4-hydroxy-2,2,3-trimethylcyclopent-3-enyl]acetic acid 0
              [(2S,4S)-2-[(1R)-1-amino-2-hydroxyethyl]-4-(1H-imidazol-4-ylmethyl)-5-oxoimidazolidin-1-yl]acetic acid 0
              [(2S,4S)-2-[(1R)-1-amino-2-hydroxyethyl]-4-(4-hydroxybenzyl)-5-oxoimidazolidin-1-yl]acetic acid 0
              [(2S,4S)-2-[(1R)-1-amino-2-sulfanylethyl]-4-(4-hydroxybenzyl)-5-oxoimidazolidin-1-yl]acetic acid 0
              [5-fluoro-1-(4-isopropylbenzylidene)-2-methylinden-3-yl]acetic acid 0
              \{(2R)-2-[(1S)-1-aminoethyl]-2-hydroxy-4-methylidene-5-oxoimidazolidin-1-yl\}acetic acid 0
              \{(2R)-2-[(1S,2R)-1-amino-2-hydroxypropyl]-2-hydroxy-4,5-dioxoimidazolidin-1-yl\}acetic acid 0
              \{4-[(carboxymethoxy)carbonyl]-3,3-dioxido-1-oxonaphtho[1,2-d]-1,2-thiazol-2(1H)-yl\}acetic acid 0
              \{[5-(3-\{[1-(benzylsulfonyl)piperidin-4-yl]amino\}phenyl)-4-bromo-2-(2H-tetrazol-5-yl)thiophen-3-yl]oxy\}acetic acid 0
              \{[5-(5-nitro-2-furyl)-1,3,4-oxadiazol-2-yl]thio\}acetic acid 0
              acetamidine + 0
              acetate ester + 19
              acetimidic acid + 0
              acetyl chloride 0
              acetyl group + 0
              acetyl-CoA + 0
              acetyloxy group 0
              arsenoacetic acid 0
              biphenyl-4-ylacetic acid + 0
              bis(4-chlorophenyl)acetic acid 0
              carboxymethyl group + 1
              chloroacetic acid + 0
              cyanoacetic acid + 0
              cyclohexylacetic acid 0
              dibromoacetic acid 0
              dichloroacetic acid + 0
              diflorasone diacetate 0
              difluoroacetic acid 0
              diphenylacetic acid 0
              etacrynic acid 0
              glycolic acid + 0
              haloacetic acid + 0
              hydroxy(phenyl)2-thienylacetic acid 0
              ibufenac 0
              imidazol-1-ylacetic acid 0
              imidazol-2-ylacetic acid 0
              imidazol-4-ylacetic acid 0
              imidazol-5-ylacetic acid 0
              indole-1-acetic acid 0
              indole-3-acetic acids + 3
              lonazolac 0
              magnesium acetate 0
              mandelic acid + 0
              methoxyacetic acid 0
              methylenecarbonyl group 0
              naphthylacetic acid + 0
              phenylacetic acid + 0
              phosphonoacetic acid + 0
              phosphonoacetohydroxamic acid 0
              pirinixic acid 0
              sulfoacetic acid + 0
              sulindac + 2
              triacetin 0
              trichloroacetic acid + 0
              trifluoroacetic acid + 0
              uracil-6-ylacetic acid 0
              zomepirac 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 828
    subatomic particle 812
      composite particle 812
        hadron 812
          baryon 812
            nucleon 812
              atomic nucleus 812
                atom 812
                  main group element atom 800
                    p-block element atom 797
                      carbon group element atom 769
                        carbon atom 765
                          organic molecular entity 765
                            organic group 354
                              organic divalent group 352
                                organodiyl group 352
                                  carbonyl group 351
                                    carbonyl compound 351
                                      carboxylic acid 237
                                        monocarboxylic acid 131
                                          acetic acid 41
                                            (1-hydroxycyclohexyl)acetic acid + 0
                                            (2,2,2-trifluoroethoxy)acetic acid + 0
                                            (2,2,3-trimethyl-5-oxocyclopent-3-en-1-yl)acetic acid + 0
                                            (2,6-dihydroxyphenyl)acetic acid 0
                                            (2-hydroxyphenyl)acetic acid 0
                                            (2S)-(\{(5Z)-5-[(5-ethylfuran-2-yl)methylidene]-4-oxo-4,5-dihydro-1,3-thiazol-2-yl\}amino)(4-fluorophenyl)acetic acid 0
                                            (2S)-[(2S,3S,4S,5S)-1,3,4,5-tetrahydroxy-4-(hydroxymethyl)piperidin-2-yl](L-tyrosylamino)acetic acid + 0
                                            (3-\{(1R)-3-(3,4-dimethoxyphenyl)-1-[(\{(2S)-1-[(2S)-2-(3,4,5-trimethoxyphenyl)butanoyl]piperidin-2-yl\}carbonyl)oxy]propyl\}phenoxy)acetic acid 0
                                            (3-amino-2,5-dioxopyrrolidin-1-yl)acetic acid 0
                                            (3-chloro-4-hydroxyphenyl)acetic acid 0
                                            (3Z)-hex-3-en-1-yl acetate 0
                                            (4-oxo-3-\{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl\}-3,4-dihydrophthalazin-1-yl)acetic acid 0
                                            (5-fluoro-2-\{[(4,5,7-trifluoro-1,3-benzothiazol-2-yl)methyl]carbamoyl\}phenoxy)acetic acid 0
                                            1-O-palmityl-2-acetyl-sn-glycerol + 0
                                            1-alkyl-2-acetylglycerol + 0
                                            1-hexadecyl-2-acetyl-sn-glycero-3-phosphoethanolamine 0
                                            1-methyl-4-imidazoleacetic acid 0
                                            1-palmitoyl-2-acetyl-sn-glycero-3-phosphocholine 0
                                            1-palmityl-2-acetyl-sn-glycero-3-phosphate 0
                                            1-stearoyl-2-acetyl-sn-glycero-3-phosphocholine 0
                                            2-acetyl-sn-glycero-3-phosphocholine 0
                                            2-thienylacetic acid + 0
                                            2H-imidazol-4-ylacetic acid 0
                                            3-hydroxyphenylacetic acid 0
                                            3-methylphenylacetic acid 0
                                            4-chlorophenylacetic acid 0
                                            4-hydroxyphenylacetic acid + 0
                                            6-\{[1-(benzylsulfonyl)piperidin-4-yl]amino\}-3-(carboxymethoxy)thieno[3,2-b][1]benzothiophene-2-carboxylic acid 0
                                            N-acetyl-amino acid + 20
                                            N-phenylacetamide + 1
                                            O-acetylcarnitine + 1
                                            [(1S)-4-hydroxy-2,2,3-trimethylcyclopent-3-enyl]acetic acid 0
                                            [(2S,4S)-2-[(1R)-1-amino-2-hydroxyethyl]-4-(1H-imidazol-4-ylmethyl)-5-oxoimidazolidin-1-yl]acetic acid 0
                                            [(2S,4S)-2-[(1R)-1-amino-2-hydroxyethyl]-4-(4-hydroxybenzyl)-5-oxoimidazolidin-1-yl]acetic acid 0
                                            [(2S,4S)-2-[(1R)-1-amino-2-sulfanylethyl]-4-(4-hydroxybenzyl)-5-oxoimidazolidin-1-yl]acetic acid 0
                                            [5-fluoro-1-(4-isopropylbenzylidene)-2-methylinden-3-yl]acetic acid 0
                                            \{(2R)-2-[(1S)-1-aminoethyl]-2-hydroxy-4-methylidene-5-oxoimidazolidin-1-yl\}acetic acid 0
                                            \{(2R)-2-[(1S,2R)-1-amino-2-hydroxypropyl]-2-hydroxy-4,5-dioxoimidazolidin-1-yl\}acetic acid 0
                                            \{4-[(carboxymethoxy)carbonyl]-3,3-dioxido-1-oxonaphtho[1,2-d]-1,2-thiazol-2(1H)-yl\}acetic acid 0
                                            \{[5-(3-\{[1-(benzylsulfonyl)piperidin-4-yl]amino\}phenyl)-4-bromo-2-(2H-tetrazol-5-yl)thiophen-3-yl]oxy\}acetic acid 0
                                            \{[5-(5-nitro-2-furyl)-1,3,4-oxadiazol-2-yl]thio\}acetic acid 0
                                            acetamidine + 0
                                            acetate ester + 19
                                            acetimidic acid + 0
                                            acetyl chloride 0
                                            acetyl group + 0
                                            acetyl-CoA + 0
                                            acetyloxy group 0
                                            arsenoacetic acid 0
                                            biphenyl-4-ylacetic acid + 0
                                            bis(4-chlorophenyl)acetic acid 0
                                            carboxymethyl group + 1
                                            chloroacetic acid + 0
                                            cyanoacetic acid + 0
                                            cyclohexylacetic acid 0
                                            dibromoacetic acid 0
                                            dichloroacetic acid + 0
                                            diflorasone diacetate 0
                                            difluoroacetic acid 0
                                            diphenylacetic acid 0
                                            etacrynic acid 0
                                            glycolic acid + 0
                                            haloacetic acid + 0
                                            hydroxy(phenyl)2-thienylacetic acid 0
                                            ibufenac 0
                                            imidazol-1-ylacetic acid 0
                                            imidazol-2-ylacetic acid 0
                                            imidazol-4-ylacetic acid 0
                                            imidazol-5-ylacetic acid 0
                                            indole-1-acetic acid 0
                                            indole-3-acetic acids + 3
                                            lonazolac 0
                                            magnesium acetate 0
                                            mandelic acid + 0
                                            methoxyacetic acid 0
                                            methylenecarbonyl group 0
                                            naphthylacetic acid + 0
                                            phenylacetic acid + 0
                                            phosphonoacetic acid + 0
                                            phosphonoacetohydroxamic acid 0
                                            pirinixic acid 0
                                            sulfoacetic acid + 0
                                            sulindac + 2
                                            triacetin 0
                                            trichloroacetic acid + 0
                                            trifluoroacetic acid + 0
                                            uracil-6-ylacetic acid 0
                                            zomepirac 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.