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ONTOLOGY REPORT - ANNOTATIONS


Term:prostaglandin I2
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Accession:CHEBI:15552 term browser browse the term
Definition:A prostaglandins I that has formula C20H32O5.
Synonyms:exact_synonym: (5Z,13E,15S)-6,9alpha-epoxy-11alpha,15-dihydroxyprosta-5,13-dienoic acid
 related_synonym: (5Z,13E)-(15S)-6,9alpha-Epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate;   (5Z,9alpha,11alpha,13E,15S)-6,9-epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid;   Epoprostenol;   Flolan;   Formula=C20H32O5;   InChI=1S/C20H32O5/c1-2-3-4-7-14(21)10-11-16-17-12-15(8-5-6-9-20(23)24)25-19(17)13-18(16)22/h8,10-11,14,16-19,21-22H,2-7,9,12-13H2,1H3,(H,23,24)/b11-10+,15-8-/t14-,16+,17+,18+,19-/m0/s1;   InChIKey=KAQKFAOMNZTLHT-OZUDYXHBSA-N;   PGI2;   PGX;   Prostacyclin;   SMILES=[H][C@]12C[C@@H](O)[C@H](\\C=C\\[C@@H](O)CCCCC)[C@@]1([H])C\\C(O2)=C\\CCCC(O)=O;   Vasocyclin;   prostaglandin X
 alt_id: CHEBI:10912;   CHEBI:245;   CHEBI:26331
 xref: Beilstein:1690090 "ChemIDplus";   CAS:35121-78-9 "ChemIDplus";   CAS:35121-78-9 "KEGG COMPOUND";   DrugBank:DB01240;   Drug_Central:1034 "DrugCentral";   KEGG:C01312;   KEGG:D00106;   LIPID_MAPS_instance:LMFA03010087 "LIPID MAPS"
 xref_mesh: MESH:D011464
 cyclic_relationship: is_conjugate_acid_of CHEBI:57403


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prostaglandin I2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ace angiotensin I converting enzyme JBrowse link 10 94,170,766 94,213,831 RGD:6480464
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Fbn1 fibrillin 1 JBrowse link 3 117,569,708 117,766,160 RGD:6480464
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:6480464
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Kng2 kininogen 2 JBrowse link 11 81,509,185 81,516,759 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Pdgfa platelet derived growth factor subunit A JBrowse link 12 17,734,141 17,756,186 RGD:6480464
G Ppargc1a PPARG coactivator 1 alpha JBrowse link 14 63,095,291 63,190,688 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        biochemical role 19138
          metabolite 19106
            eukaryotic metabolite 18748
              animal metabolite 18486
                mammalian metabolite 18468
                  mouse metabolite 17880
                    prostaglandin I2 13
                      15-dehydro-prostaglandin I2 0
                      19-hydroxyprostaglandin I2 0
                      prostaglandin I2 2-glyceryl ester 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      carboxylic acid 17923
                                        monocarboxylic acid 17256
                                          fatty acid 15814
                                            fatty acid derivative 1008
                                              icosanoid 450
                                                prostanoid 393
                                                  prostaglandin 388
                                                    prostaglandins I 13
                                                      prostaglandin I2 13
                                                        15-dehydro-prostaglandin I2 0
                                                        19-hydroxyprostaglandin I2 0
                                                        prostaglandin I2 2-glyceryl ester 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.