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ONTOLOGY REPORT - ANNOTATIONS


Term:thromboxane A2
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Accession:CHEBI:15627 term browser browse the term
Definition:A thromboxane which is produced by activated platelets and has prothrombotic properties: it stimulates activation of new platelets as well as increases platelet aggregation.
Synonyms:exact_synonym: (5Z,13E,15S)-9alpha,11alpha-epoxy-15-hydroxythromboxa-5,13-dien-1-oic acid
 related_synonym: (5Z,13E)-(15S)-9alpha,11alpha-Epoxy-15-hydroxythromboxa-5,13-dienoate;   (5Z,9alpha,11alpha,13E,15S)-9,11-Epoxy-15-hydroxythromboxa-5,13-dien-1-oic acid;   9S,11S-epoxy,15S-hydroxy-thromboxa-5Z,13E-dien-1-oic acid;   Formula=C20H32O5;   InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18-14-20(24-17)25-18)10-7-4-5-8-11-19(22)23/h4,7,12-13,15-18,20-21H,2-3,5-6,8-11,14H2,1H3,(H,22,23)/b7-4-,13-12+/t15-,16+,17+,18-,20+/m0/s1;   InChIKey=DSNBHJFQCNUKMA-SCKDECHMSA-N;   SMILES=CCCCC[C@H](O)\\C=C\\[C@H]1O[C@H]2C[C@H](O2)[C@@H]1C\\C=C/CCCC(O)=O;   TXA-2;   TXA2
 alt_id: CHEBI:10915;   CHEBI:18589;   CHEBI:26993;   CHEBI:9575
 xref: CAS:57576-52-0 "KEGG COMPOUND";   KEGG:C02198;   LIPID_MAPS_instance:LMFA03030001 "LIPID MAPS"
 xref_mesh: MESH:D013928
 cyclic_relationship: is_conjugate_acid_of CHEBI:57445


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thromboxane A2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col10a1 collagen type X alpha 1 chain JBrowse link 20 41,180,295 41,190,664 RGD:6480464
G Fbn1 fibrillin 1 JBrowse link 3 117,569,708 117,766,160 RGD:6480464
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Runx2 RUNX family transcription factor 2 JBrowse link 9 18,564,743 18,773,092 RGD:6480464
carbocyclic thromboxane A2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tnfrsf11b TNF receptor superfamily member 11B JBrowse link 7 93,798,580 93,826,586 RGD:6480464
G Tnfsf11 TNF superfamily member 11 JBrowse link 15 60,482,527 60,512,704 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19734
    chemical entity 19732
      molecular entity 19729
        main group molecular entity 19614
          gas molecular entity 17247
            oxirane 5317
              epoxide 5315
                epoxy monocarboxylic acid 22
                  thromboxane A2 7
                    18-hydroxythromboxane A2 0
                    19-hydroxythromboxane A2 0
                    carbocyclic thromboxane A2 + 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19734
    subatomic particle 19730
      composite particle 19730
        hadron 19730
          baryon 19730
            nucleon 19730
              atomic nucleus 19730
                atom 19730
                  main group element atom 19614
                    p-block element atom 19614
                      carbon group element atom 19506
                        carbon atom 19500
                          organic molecular entity 19500
                            organic group 18414
                              organic divalent group 18406
                                organodiyl group 18406
                                  carbonyl group 18295
                                    carbonyl compound 18295
                                      carboxylic acid 17963
                                        monocarboxylic acid 17265
                                          fatty acid 15819
                                            fatty acid derivative 1018
                                              icosanoid 452
                                                prostanoid 395
                                                  thromboxane 14
                                                    thromboxanes A 7
                                                      thromboxane A2 7
                                                        18-hydroxythromboxane A2 0
                                                        19-hydroxythromboxane A2 0
                                                        carbocyclic thromboxane A2 + 2
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