Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:5-formyltetrahydrofolic acid
go back to main search page
Accession:CHEBI:15640 term browser browse the term
Definition:A formyltetrahydrofolic acid in which the formyl group is located at position 5.
Synonyms:exact_synonym: N-[4-({[2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid
 related_synonym: (5-formyl-5,6,7,8-tetrahydropteroyl)glutamate;   10-Formyl-7,8-dihydrofolic acid;   5-Formyl-5,6,7,8-tetrahydrofolic acid;   5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid;   5-Formyltetrahydrofolate;   Acide folinique;   Folinic acid;   Formula=C20H23N7O7;   InChI=1S/C20H23N7O7/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32)/t12?,13-/m0/s1;   InChIKey=VVIAGPKUTFNRDU-ABLWVSNPSA-N;   L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid;   Leucovorin;   Leucovorinum;   N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid;   N5-Formyl-5,6,7,8-tetrahydrofolic acid;   N5-Formyltetrahydrofolic acid;   SMILES=[H]C(=O)N1C(CNc2ccc(cc2)C(=O)N[C@@H](CCC(O)=O)C(O)=O)CNc2nc(N)[nH]c(=O)c12;   folinate
 alt_id: CHEBI:12127;   CHEBI:18607;   CHEBI:2057
 xref: CAS:58-05-9 "ChemIDplus";   CAS:58-05-9 "KEGG COMPOUND";   DrugBank:DB03256;   Drug_Central:1232 "DrugCentral";   KEGG:C03479;   KEGG:D07986;   LINCS:LSM-5146
 xref_mesh: MESH:D002955
 xref: Reaxys:101688 "Reaxys";   Wikipedia:Folinic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:65340


show annotations for term's descendants       view all columns           Sort by:
 
5-formyltetrahydrofolic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc2 ATP binding cassette subfamily C member 2 JBrowse link 1 263,554,426 263,612,556 RGD:6480464
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:6480464
G Angptl2 angiopoietin-like 2 JBrowse link 3 12,262,822 12,292,665 RGD:6480464
G Arl6ip5 ADP-ribosylation factor like GTPase 6 interacting protein 5 JBrowse link 4 129,574,363 129,598,240 RGD:6480464
G Atp5po ATP synthase peripheral stalk subunit OSCP JBrowse link 11 32,081,606 32,087,918 RGD:6480464
G Axin2 axin 2 JBrowse link 10 97,212,483 97,238,824 RGD:6480464
G Bglap bone gamma-carboxyglutamate protein JBrowse link 2 187,741,770 187,748,445 RGD:6480464
G Boll boule homolog, RNA binding protein JBrowse link 9 61,836,517 61,975,640 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:6480464
G Ccne1 cyclin E1 JBrowse link 1 94,485,830 94,495,112 RGD:6480464
G Cdc45 cell division cycle 45 JBrowse link 11 86,328,785 86,354,099 RGD:6480464
G Cdc6 cell division cycle 6 JBrowse link 10 86,819,477 86,833,301 RGD:6480464
G Cdk1 cyclin-dependent kinase 1 JBrowse link 20 20,576,341 20,591,510 RGD:6480464
G Cdk2 cyclin dependent kinase 2 JBrowse link 7 3,124,953 3,132,533 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:6480464
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 JBrowse link 8 62,798,317 62,809,848 RGD:6480464
G Dhfr dihydrofolate reductase JBrowse link 2 21,931,887 21,958,927 RGD:6480464
G Dpyd dihydropyrimidine dehydrogenase JBrowse link 2 221,823,692 222,694,627 RGD:6480464
G Drd5 dopamine receptor D5 JBrowse link 14 77,220,579 77,222,006 RGD:6480464
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:6480464
G Eml2 EMAP like 2 JBrowse link 1 80,087,684 80,118,784 RGD:6480464
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 1 80,256,973 80,268,198 RGD:6480464
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 1 80,293,574 80,307,334 RGD:6480464
G F8 coagulation factor VIII JBrowse link 18 367,862 399,242 RGD:6480464
G Fabp4 fatty acid binding protein 4 JBrowse link 2 93,792,666 93,797,267 RGD:6480464
G Fshb follicle stimulating hormone subunit beta JBrowse link 3 98,088,321 98,092,131 RGD:6480464
G G6pd glucose-6-phosphate dehydrogenase JBrowse link X 156,274,800 156,293,935 RGD:6480464
G Hand2 heart and neural crest derivatives expressed 2 JBrowse link 16 36,371,489 36,373,551 RGD:6480464
G Hspb1 heat shock protein family B (small) member 1 JBrowse link 12 23,839,390 23,841,051 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Lef1 lymphoid enhancer binding factor 1 JBrowse link 2 236,232,115 236,345,061 RGD:6480464
G Lgals8 galectin 8 JBrowse link 17 66,487,451 66,515,316 RGD:6480464
G Lhb luteinizing hormone subunit beta JBrowse link 1 101,409,992 101,413,725 RGD:6480464
G LOC102548162 zinc finger protein 582-like JBrowse link 1 71,206,073 71,228,209 RGD:6480464
G Mat2a methionine adenosyltransferase 2A JBrowse link 4 100,297,478 100,303,047 RGD:6480464
G Mthfr methylenetetrahydrofolate reductase JBrowse link 5 164,844,642 164,864,360 RGD:6480464
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:6480464
G Serpine2 serpin family E member 2 JBrowse link 9 85,560,852 85,629,410 RGD:6480464
G Sfrp1 secreted frizzled-related protein 1 JBrowse link 16 73,372,007 73,410,777 RGD:6480464
G Slc19a1 solute carrier family 19 member 1 JBrowse link 20 12,334,675 12,354,517 RGD:6480464
G Slc22a6 solute carrier family 22 member 6 JBrowse link 1 224,824,809 224,833,284 RGD:6480464
G Slc22a8 solute carrier family 22 member 8 JBrowse link 1 224,799,444 224,818,482 RGD:6480464
G Slc46a1 solute carrier family 46 member 1 JBrowse link 10 65,728,508 65,741,708 RGD:6480464
G Sp7 Sp7 transcription factor JBrowse link 7 143,957,316 143,967,488 RGD:6480464
G Star steroidogenic acute regulatory protein JBrowse link 16 71,036,204 71,040,847 RGD:6480464
G Tymp thymidine phosphorylase JBrowse link 7 130,342,481 130,347,845 RGD:6480464
G Tyms thymidylate synthetase JBrowse link 9 121,918,875 121,931,564 RGD:6480464
G Wnt10b Wnt family member 10B JBrowse link 7 140,448,284 140,466,159 RGD:6480464
G Xrcc1 X-ray repair cross complementing 1 JBrowse link 1 81,412,635 81,441,680 RGD:6480464
G Zfp637 zinc finger protein 637 JBrowse link 4 149,857,127 149,882,828 RGD:6480464
G Zrsr2 zinc finger (CCCH type), RNA binding motif and serine/arginine rich 2 JBrowse link X 32,304,707 32,327,419 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        biochemical role 19138
          metabolite 19106
            prokaryotic metabolite 18227
              bacterial metabolite 18227
                Escherichia coli metabolite 18121
                  5-formyltetrahydrofolic acid 54
                    (6S)-5-formyltetrahydrofolic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      carboxylic acid 17923
                                        amino acid 12315
                                          alpha-amino acid 7422
                                            L-alpha-amino acid 7079
                                              glutamine family amino acid 5338
                                                L-glutamic acid 5240
                                                  L-glutamic acid derivative 3694
                                                    folic acids 3690
                                                      tetrahydrofolic acid 63
                                                        formyltetrahydrofolic acid 55
                                                          5-formyltetrahydrofolic acid 54
                                                            (6S)-5-formyltetrahydrofolic acid 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.