Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:leukotriene E4
go back to main search page
Accession:CHEBI:15650 term browser browse the term
Definition:A leukotriene that is (7E,9E,11Z,14Z)-icosa-7,9,11,14-tetraenoic acid substituted by a hydroxy group at position 5 (5S) and an L-cystein-S-yl group at position 6 (6R).
Synonyms:exact_synonym: (5S,6R,7E,9E,11Z,14Z)-6-(L-cystein-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoic acid;   S-{(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]pentadeca-2,4,6,9-tetraen-1-yl}-L-cysteine
 related_synonym: (5S-(5R*,6S*(S*),7E,9E,11Z,14Z))-6-((2-Amino-2-carboxyethyl)thio)-5-hydroxy-7,9,11,14-eicosatetraenoic acid;   (7E,9E,11Z,14Z)-(5S,6R)-6-(Cystein-S-yl)-5-hydroxyeicosa-7,9,11,14-tetraenoate;   (7E,9E,11Z,14Z)-(5S,6R)-6-(Cystein-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate;   5S-hydroxy,6R-(S-cysteinyl),7E,9E,11Z,14Z-eicosatetraenoic acid;   Formula=C23H37NO5S;   InChI=1S/C23H37NO5S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-21(30-18-19(24)23(28)29)20(25)15-14-17-22(26)27/h6-7,9-13,16,19-21,25H,2-5,8,14-15,17-18,24H2,1H3,(H,26,27)(H,28,29)/b7-6-,10-9-,12-11+,16-13+/t19-,20-,21+/m0/s1;   InChIKey=OTZRAYGBFWZKMX-FRFVZSDQSA-N;   LTE4;   SMILES=CCCCC\\C=C/C\\C=C/C=C/C=C/[C@@H](SC[C@H](N)C(O)=O)[C@@H](O)CCCC(O)=O
 alt_id: CHEBI:10936;   CHEBI:18612;   CHEBI:25027;   CHEBI:261;   CHEBI:6424
 xref: CAS:75715-89-8 "ChemIDplus";   CAS:75715-89-8 "KEGG COMPOUND";   KEGG:C05952;   LIPID_MAPS_instance:LMFA03020002 "LIPID MAPS"
 xref_mesh: MESH:D017999
 xref: PMID:19291727 "Europe PMC"
 cyclic_relationship: is_conjugate_acid_of CHEBI:57462


show annotations for term's descendants       view all columns           Sort by:
 
leukotriene E4 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox5 arachidonate 5-lipoxygenase JBrowse link 4 148,398,004 148,446,308 RGD:6480464
G Cysltr1 cysteinyl leukotriene receptor 1 JBrowse link X 77,671,028 77,700,491 RGD:6480464
G Cysltr2 cysteinyl leukotriene receptor 2 JBrowse link 15 54,903,290 54,941,742 RGD:6480464
G Gpr17 G protein-coupled receptor 17 JBrowse link 18 24,733,306 24,739,194 RGD:6480464
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:6480464
G Mgst1 microsomal glutathione S-transferase 1 JBrowse link 4 172,119,382 172,134,609 RGD:6480464
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming JBrowse link 1 214,725,482 214,756,653 RGD:6480464
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19741
    role 19688
      application 19339
        refrigerant 17093
          ammonia 16691
            organic amino compound 16690
              amino acid 12445
                amino dicarboxylic acid 9
                  leukotriene E4 8
                    16-carboxy-17,18,19,20-tetranor-leukotriene E3 0
                    16-carboxy-Delta(13)-17,18,19,20-tetranor-leukotriene E4 + 0
                    18-carboxy-19,20-dinor-leukotriene E4 0
                    20-carboxyleukotriene E4 0
                    20-hydroxy-leukotriene E4 0
                    20-oxoleukotriene E4 0
                    N-acetylleukotriene E4 0
                    leukotriene E4 methyl ester 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    p-block element atom 19622
                      carbon group element atom 19515
                        carbon atom 19508
                          organic molecular entity 19508
                            organic group 18423
                              organic divalent group 18414
                                organodiyl group 18414
                                  carbonyl group 18301
                                    carbonyl compound 18301
                                      carboxylic acid 17966
                                        amino acid 12445
                                          alpha-amino acid 7644
                                            L-alpha-amino acid 7309
                                              serine family amino acid 1770
                                                L-cysteine 1101
                                                  L-cysteine derivative 1089
                                                    S-substituted L-cysteine 136
                                                      L-cysteine thioether 56
                                                        leukotriene E4 8
                                                          16-carboxy-17,18,19,20-tetranor-leukotriene E3 0
                                                          16-carboxy-Delta(13)-17,18,19,20-tetranor-leukotriene E4 + 0
                                                          18-carboxy-19,20-dinor-leukotriene E4 0
                                                          20-carboxyleukotriene E4 0
                                                          20-hydroxy-leukotriene E4 0
                                                          20-oxoleukotriene E4 0
                                                          N-acetylleukotriene E4 0
                                                          leukotriene E4 methyl ester 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.