Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


Term:leukotriene A4
go back to main search page
Accession:CHEBI:15651 term browser browse the term
Definition:A leukotriene that is the (5S,6S)-epoxy derivative of (7E,9E,11Z,14Z)-icosa-7,9,11,14-tetraenoic acid.
Synonyms:exact_synonym: (5S,6S,7E,9E,11Z,14Z)-5,6-epoxyicosa-7,9,11,14-tetraenoic acid
 related_synonym: (5S,6S,7E,9E,11Z,14Z)-5,6-Epoxyicosa-7,9,11,14-tetraenoate;   (7E,9E,11Z,14Z)-(5S,6S)-5,6-Epoxyeicosa-7,9,11,14-tetraenoate;   (7E,9E,11Z,14Z)-(5S,6S)-5,6-Epoxyeicosa-7,9,11,14-tetraenoic acid;   5(S)-5,6-oxido-7,9-trans-11,14-cis-eicosatetraenoic acid;   5S,6S-epoxy-7E,9E,11Z,14Z-eicosatetraenoic acid;   5S,6S-leukotriene A4;   Formula=C20H30O3;   InChI=1S/C20H30O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18-19(23-18)16-14-17-20(21)22/h6-7,9-13,15,18-19H,2-5,8,14,16-17H2,1H3,(H,21,22)/b7-6-,10-9-,12-11+,15-13+/t18-,19-/m0/s1;   InChIKey=UFPQIRYSPUYQHK-WAQVJNLQSA-N;   LTA4;   Oxiranebutanoic acid, 3-(1,3,5,8-tetradecatetraenyl)-, (2S-(2alpha,3beta(1E,3Z,5Z,8Z)))-;   SMILES=CCCCC\\C=C/C\\C=C/C=C/C=C/[C@@H]1O[C@H]1CCCC(O)=O
 alt_id: CHEBI:10937;   CHEBI:14503;   CHEBI:25023;   CHEBI:6420
 xref: CAS:72059-45-1 "ChemIDplus";   CAS:72059-45-1 "KEGG COMPOUND";   KEGG:C00909;   LIPID_MAPS_instance:LMFA03020023 "LIPID MAPS"
 xref_mesh: MESH:D017572
 xref: PMID:1667967 "Europe PMC";   PMID:19531649 "Europe PMC";   PMID:8017792 "Europe PMC";   Reaxys:5756170 "Reaxys"
 cyclic_relationship: is_conjugate_acid_of CHEBI:57463

show annotations for term's descendants       view all columns           Sort by:
leukotriene A4 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox5 arachidonate 5-lipoxygenase JBrowse link 4 148,398,004 148,446,308 RGD:6480464
G Lta4h leukotriene A4 hydrolase JBrowse link 7 34,288,333 34,320,243 RGD:6480464
G Mgst1 microsomal glutathione S-transferase 1 JBrowse link 4 172,119,382 172,134,609 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    chemical entity 19667
      atom 19665
        nonmetal atom 19531
          carbon atom 19420
            organic molecular entity 19420
              lipid 16950
                fatty acid 15814
                  long-chain fatty acid 1638
                    leukotriene A4 3
                      4,5-leukotriene A4 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      carboxylic acid 17923
                                        monocarboxylic acid 17256
                                          fatty acid 15814
                                            unsaturated fatty acid 888
                                              polyunsaturated fatty acid 646
                                                fatty acid 20:4 309
                                                  icosatetraenoic acid 309
                                                    icosa-7,9,11,14-tetraenoic acid 44
                                                      leukotriene A4 3
                                                        4,5-leukotriene A4 0
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.