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ONTOLOGY REPORT - ANNOTATIONS


Term:enoxacin
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Accession:CHEBI:157175 term browser browse the term
Definition:A 1,8-naphthyridine derivative that is 1,4-dihydro-1,8-naphthyridine with an ethyl group at the 1 position, a carboxy group at the 3-position, an oxo sustituent at the 4-position, a fluoro substituent at the 5-position and a piperazin-1-yl group at the 7 position. An antibacterial, it is used in the treatment of urinary-tract infections and gonorrhoea.
Synonyms:related_synonym: 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid;   1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid;   Formula=C15H17FN4O3;   InChI=1S/C15H17FN4O3/c1-2-19-8-10(15(22)23)12(21)9-7-11(16)14(18-13(9)19)20-5-3-17-4-6-20/h7-8,17H,2-6H2,1H3,(H,22,23);   InChIKey=IDYZIJYBMGIQMJ-UHFFFAOYSA-N;   SMILES=CCn1cc(C(O)=O)c(=O)c2cc(F)c(nc12)N1CCNCC1;   enoxacine;   enoxacino;   enoxacinum
 alt_id: CHEBI:4796
 xref: Beilstein:3628995 "Beilstein";   CAS:74011-58-8 "ChemIDplus";   CAS:74011-58-8 "KEGG COMPOUND";   DrugBank:DB00467;   Drug_Central:1013 "DrugCentral";   KEGG:C06979;   KEGG:D00310;   LINCS:LSM-5848
 xref_mesh: MESH:D015365
 xref: PMID:16644219 "ChEMBL";   PMID:8741236 "Europe PMC";   Patent:EP9425;   Patent:US4352803;   Patent:US4359578;   Reaxys:3628995 "Reaxys";   VSDB:1896;   Wikipedia:Enoxacin


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enoxacin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464
G Nos1 nitric oxide synthase 1 JBrowse link 12 44,214,949 44,405,530 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      biological role 19673
        antimicrobial agent 17211
          quinolone antibiotic 576
            enoxacin 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic molecule 19417
                              organic cyclic compound 19184
                                organic heterocyclic compound 18262
                                  organic heteropolycyclic compound 17570
                                    organic heterobicyclic compound 16240
                                      mancude organic heterobicyclic parent 5176
                                        naphthyridine 761
                                          1,8-naphthyridine 381
                                            1,8-naphthyridine derivative 381
                                              enoxacin 3
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