Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dichloromethane
go back to main search page
Accession:CHEBI:15767 term browser browse the term
Definition:A member of the class of chloromethanes that is methane in which two of the hydrogens have been replaced by chlorine. A dense, non-flammible colourless liquid at room temperature (b.p. 40degreeC, d = 1.33) which is immiscible with water, it is widely used as a solvent, a paint stripper, and for the removal of caffeine from coffee and tea.
Synonyms:related_synonym: DCM;   Dichlormethan;   Formula=CH2Cl2;   InChI=1S/CH2Cl2/c2-1-3/h1H2;   InChIKey=YMWUJEATGCHHMB-UHFFFAOYSA-N;   Methylenchlorid;   Methylene chloride;   Methylene dichloride;   SMILES=[H]C([H])(Cl)Cl;   chlorure de methylene;   methane dichloride;   methylene bichloride
 alt_id: CHEBI:14139;   CHEBI:23701;   CHEBI:4504
 xref: Beilstein:1730800;   CAS:75-09-2;   Gmelin:1302;   HMDB:HMDB0031548;   KEGG:C02271;   KEGG:D02330
 xref_mesh: MESH:D008752
 xref: MetaCyc:CPD-681;   PMID:11884241;   PMID:19091298;   PMID:8465711;   Patent:US2792435;   Patent:US2979541;   Patent:US3126419;   Reaxys:1730800;   UM-BBD_compID:c0233;   Wikipedia:Dichloromethane


show annotations for term's descendants           Sort by:
 
dichloromethane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 multiple interactions ISO [Particulate Matter co-treated with Methylene Chloride] results in decreased expression of ADRB1 mRNA CTD PMID:30503853 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [[Particulate Matter co-treated with Methylene Chloride] results in increased abundance of Polycyclic Aromatic Hydrocarbons] which affects the expression of AKT1 mRNA CTD PMID:29335169 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Ar androgen receptor decreases expression ISO Methylene Chloride results in decreased expression of AR mRNA CTD PMID:28392392 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like decreases expression ISO Methylene Chloride results in decreased expression of ARNTL mRNA CTD PMID:28392392 NCBI chr 1:178,039,002...178,137,469
Ensembl chr 1:178,039,063...178,137,465
JBrowse link
G Atf5 activating transcription factor 5 decreases expression ISO Methylene Chloride results in decreased expression of ATF5 mRNA CTD PMID:28392392 NCBI chr 1:100,807,821...100,812,410
Ensembl chr 1:100,808,241...100,810,522
JBrowse link
G Bach2 BTB domain and CNC homolog 2 decreases expression ISO Methylene Chloride results in decreased expression of BACH2 mRNA CTD PMID:28392392 NCBI chr 5:47,458,891...47,807,176
Ensembl chr 5:47,546,014...47,807,166
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [[Particulate Matter co-treated with Methylene Chloride] results in increased abundance of Polycyclic Aromatic Hydrocarbons] which affects the expression of BCL2 mRNA CTD PMID:29335169 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2a1 BCL2-related protein A1 increases expression ISO Methylene Chloride results in increased expression of BCL2A1 mRNA CTD PMID:20359517 NCBI chr 8:96,551,424...96,559,527
Ensembl chr 8:96,551,245...96,559,483
JBrowse link
G Bcl6 BCL6, transcription repressor increases expression ISO Methylene Chloride results in increased expression of BCL6 mRNA CTD PMID:20359517, PMID:28392392 NCBI chr11:80,255,790...80,279,075
Ensembl chr11:80,255,790...80,279,075
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 increases expression ISO Methylene Chloride results in increased expression of BHLHE40 mRNA CTD PMID:28392392 NCBI chr 4:140,703,619...140,709,319
Ensembl chr 4:140,703,619...140,709,319
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression ISO Methylene Chloride results in increased expression of BIRC3 mRNA CTD PMID:20359517 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Bnc1 basonuclin 1 decreases expression ISO Methylene Chloride results in decreased expression of BNC1 mRNA CTD PMID:28392392 NCBI chr 1:143,793,280...143,818,748
NCBI chr 1:143,869,440...143,878,077
Ensembl chr 1:143,793,064...143,818,706
JBrowse link
G Btg1 BTG anti-proliferation factor 1 increases expression ISO Methylene Chloride results in increased expression of BTG1 mRNA CTD PMID:20359517 NCBI chr 7:37,812,831...37,815,088
Ensembl chr 7:37,812,831...37,815,088
JBrowse link
G Casp1 caspase 1 multiple interactions ISO [[Particulate Matter co-treated with Methylene Chloride] results in increased abundance of Polycyclic Aromatic Hydrocarbons] which results in increased expression of CASP1 mRNA CTD PMID:29335169 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp3 caspase 3 multiple interactions ISO [Methylene Chloride co-treated with Biliverdine] inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased activity of CASP3 protein]; Methylene Chloride inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased activity of CASP3 protein] CTD PMID:15486963 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cat catalase multiple interactions ISO [[Particulate Matter co-treated with Methylene Chloride] results in increased abundance of Polycyclic Aromatic Hydrocarbons] which results in decreased expression of CAT mRNA; [Lipopolysaccharides co-treated with Methylene Chloride] results in increased activity of CAT protein CTD PMID:15563889, PMID:29335169 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cblb Cbl proto-oncogene B increases expression EXP Methylene Chloride results in increased expression of CBLB mRNA CTD PMID:20955722 NCBI chr11:51,037,383...51,202,761
Ensembl chr11:51,037,393...51,202,820
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 decreases expression EXP Methylene Chloride results in decreased expression of CCL5 mRNA CTD PMID:20955722 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Cd37 CD37 molecule decreases expression EXP Methylene Chloride results in decreased expression of CD37 mRNA CTD PMID:20955722 NCBI chr 1:101,230,470...101,236,061
Ensembl chr 1:101,230,533...101,236,065
JBrowse link
G Cd38 CD38 molecule increases expression EXP Methylene Chloride results in increased expression of CD38 mRNA CTD PMID:20955722 NCBI chr14:71,714,768...71,754,990
Ensembl chr14:71,715,269...71,754,672
JBrowse link
G Cd4 Cd4 molecule increases expression EXP Methylene Chloride results in increased expression of CD4 mRNA CTD PMID:20955722 NCBI chr 4:157,381,862...157,408,357
Ensembl chr 4:157,383,052...157,408,176
JBrowse link
G Cd8a CD8a molecule increases expression EXP Methylene Chloride results in increased expression of CD8A mRNA CTD PMID:20955722 NCBI chr 4:99,217,640...99,243,352
Ensembl chr 4:99,239,115...99,243,351
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO Methylene Chloride results in increased expression of CEBPB mRNA CTD PMID:28392392 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Ciita class II, major histocompatibility complex, transactivator increases expression EXP Methylene Chloride results in increased expression of CIITA mRNA CTD PMID:20955722 NCBI chr10:5,212,621...5,260,641
Ensembl chr10:5,213,350...5,260,608
JBrowse link
G Clock clock circadian regulator decreases expression ISO Methylene Chloride results in decreased expression of CLOCK mRNA CTD PMID:28392392 NCBI chr14:34,418,226...34,502,218
Ensembl chr14:34,446,616...34,502,218
JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 decreases expression ISO Methylene Chloride results in decreased expression of CREB3L1 mRNA CTD PMID:28392392 NCBI chr 3:80,892,433...80,933,283
Ensembl chr 3:80,892,435...80,933,283
JBrowse link
G Creb3l2 cAMP responsive element binding protein 3-like 2 decreases expression ISO Methylene Chloride results in decreased expression of CREB3L2 mRNA CTD PMID:28392392 NCBI chr 4:64,869,285...64,981,519
Ensembl chr 4:64,869,026...64,981,384
JBrowse link
G Crem cAMP responsive element modulator decreases expression ISO Methylene Chloride results in decreased expression of CREM mRNA CTD PMID:28392392 NCBI chr17:57,021,704...57,090,888
Ensembl chr17:57,031,766...57,090,888
JBrowse link
G Cry1 cryptochrome circadian regulator 1 decreases expression ISO Methylene Chloride results in decreased expression of CRY1 mRNA CTD PMID:28392392 NCBI chr 7:24,534,593...24,634,098
Ensembl chr 7:24,534,615...24,634,097
JBrowse link
G Cry2 cryptochrome circadian regulator 2 increases expression ISO Methylene Chloride results in increased expression of CRY2 mRNA CTD PMID:28392392 NCBI chr 3:81,314,151...81,344,143
Ensembl chr 3:81,314,149...81,344,110
JBrowse link
G Csde1 cold shock domain containing E1 increases expression ISO Methylene Chloride results in increased expression of CSDE1 mRNA CTD PMID:28392392 NCBI chr 2:205,525,194...205,552,987
Ensembl chr 2:205,525,204...205,552,991
JBrowse link
G Cth cystathionine gamma-lyase increases expression ISO Methylene Chloride results in increased expression of CTH mRNA CTD PMID:20359517 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
G Ctnnb1 catenin beta 1 increases mutagenesis ISO Methylene Chloride results in increased mutagenesis of CTNNB1 gene CTD PMID:10467420 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Cux1 cut-like homeobox 1 decreases expression ISO Methylene Chloride results in decreased expression of CUX1 mRNA CTD PMID:28392392 NCBI chr12:23,150,886...23,470,095
Ensembl chr12:23,151,180...23,445,074
JBrowse link
G Cux2 cut-like homeobox 2 decreases expression ISO Methylene Chloride results in decreased expression of CUX2 mRNA CTD PMID:28392392 NCBI chr12:40,016,774...40,221,067
Ensembl chr12:40,018,937...40,219,291
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 increases expression EXP Methylene Chloride results in increased expression of CXCR2 mRNA CTD PMID:20955722 NCBI chr 9:81,427,275...81,435,065
Ensembl chr 9:81,427,730...81,434,102
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO Methylene Chloride results in increased expression of CXCR4 mRNA CTD PMID:20359517 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO [[Particulate Matter co-treated with Methylene Chloride] results in increased abundance of Polycyclic Aromatic Hydrocarbons] which results in increased expression of CYP1A1 mRNA CTD PMID:29335169 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects expression ISO Methylene Chloride affects the expression of CYP1A2 mRNA CTD PMID:28392392 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases expression ISO Methylene Chloride results in decreased expression of CYP1B1 mRNA CTD PMID:20359517 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 affects expression ISO Methylene Chloride affects the expression of CYP2C29 mRNA CTD PMID:28392392 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
increases oxidation
increases metabolic processing
EXP
ISO
3-xylene promotes the reaction [CYP2E1 protein results in increased metabolism of Methylene Chloride]; Benzene promotes the reaction [CYP2E1 protein results in increased metabolism of Methylene Chloride]; Toluene promotes the reaction [CYP2E1 protein results in increased metabolism of Methylene Chloride]
[[Particulate Matter co-treated with Methylene Chloride] results in increased abundance of Polycyclic Aromatic Hydrocarbons] which results in increased expression of CYP2E1 mRNA
CYP2E1 protein results in increased oxidation of Methylene Chloride
CTD PMID:1664256, PMID:8889796, PMID:29335169 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp51 cytochrome P450, family 51 affects expression ISO Methylene Chloride affects the expression of CYP51 mRNA CTD PMID:28392392 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018
JBrowse link
G Dapk1 death associated protein kinase 1 increases methylation ISO Methylene Chloride results in increased methylation of DAPK1 promoter CTD PMID:15172992 NCBI chr17:4,297,038...4,454,941
Ensembl chr17:4,297,224...4,454,778
JBrowse link
G Dbp D-box binding PAR bZIP transcription factor increases expression ISO Methylene Chloride results in increased expression of DBP mRNA CTD PMID:28392392 NCBI chr 1:101,687,896...101,692,845
Ensembl chr 1:101,687,855...101,692,846
JBrowse link
G Dennd5a DENN domain containing 5A increases expression ISO Methylene Chloride results in increased expression of DENND5A mRNA CTD PMID:20359517 NCBI chr 1:174,524,047...174,588,553
Ensembl chr 1:174,524,047...174,588,529
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase affects expression ISO Methylene Chloride affects the expression of DHCR24 mRNA CTD PMID:28392392 NCBI chr 5:126,164,708...126,188,926
Ensembl chr 5:126,164,674...126,191,206
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO Methylene Chloride results in increased expression of DNAJB9 mRNA CTD PMID:20359517 NCBI chr 6:64,165,913...64,170,122
Ensembl chr 6:64,165,913...64,170,151
JBrowse link
G Ebp EBP, cholestenol delta-isomerase affects expression ISO Methylene Chloride affects the expression of EBP mRNA CTD PMID:28392392 NCBI chr  X:15,049,394...15,055,782
Ensembl chr  X:15,049,462...15,055,781
JBrowse link
G Egr1 early growth response 1 affects expression ISO Methylene Chloride affects the expression of EGR1 mRNA CTD PMID:28392392 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Egr3 early growth response 3 increases expression ISO Methylene Chloride results in increased expression of EGR3 mRNA CTD PMID:20359517 NCBI chr15:51,756,683...51,762,080
Ensembl chr15:51,756,736...51,760,722
JBrowse link
G Elf1 E74 like ETS transcription factor 1 decreases expression ISO Methylene Chloride results in decreased expression of ELF1 mRNA CTD PMID:28392392 NCBI chr15:61,772,544...61,868,442
Ensembl chr15:61,826,711...61,868,343
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 increases expression ISO Methylene Chloride results in increased expression of ELOVL6 mRNA CTD PMID:20359517 NCBI chr 2:234,187,490...234,296,124
Ensembl chr 2:234,189,105...234,296,145
Ensembl chr 2:234,189,105...234,296,145
JBrowse link
G Esr1 estrogen receptor 1 decreases expression ISO Methylene Chloride results in decreased expression of ESR1 mRNA CTD PMID:28392392 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Evi2a ecotropic viral integration site 2A increases expression ISO Methylene Chloride results in increased expression of EVI2A mRNA CTD PMID:20359517 NCBI chr10:66,870,048...66,873,948
Ensembl chr10:66,870,067...66,873,948
JBrowse link
G Fcgr1a Fc fragment of IgG receptor Ia increases expression EXP Methylene Chloride results in increased expression of FCGR1 mRNA CTD PMID:20955722 NCBI chr 2:198,430,536...198,439,453
Ensembl chr 2:198,430,530...198,458,041
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 affects expression ISO Methylene Chloride affects the expression of FDFT1 mRNA CTD PMID:28392392 NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302
JBrowse link
G Fdps farnesyl diphosphate synthase affects expression ISO Methylene Chloride affects the expression of FDPS mRNA CTD PMID:28392392 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
JBrowse link
G Filip1l filamin A interacting protein 1-like increases expression ISO Methylene Chloride results in increased expression of FILIP1L mRNA CTD PMID:20359517 NCBI chr11:45,039,488...45,275,141
Ensembl chr11:45,039,461...45,124,423
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Methylene Chloride results in decreased expression of FOS mRNA CTD PMID:28392392 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Foxa1 forkhead box A1 decreases expression ISO Methylene Chloride results in decreased expression of FOXA1 mRNA CTD PMID:28392392 NCBI chr 6:78,516,579...78,549,669
Ensembl chr 6:78,545,804...78,549,669
JBrowse link
G Foxo3 forkhead box O3 increases expression ISO Methylene Chloride results in increased expression of FOXO3 mRNA CTD PMID:28392392 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO Methylene Chloride results in increased expression of GADD45A mRNA CTD PMID:20359517 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO [[Particulate Matter co-treated with Methylene Chloride] results in increased abundance of Polycyclic Aromatic Hydrocarbons] which results in decreased expression of GCLC mRNA CTD PMID:29335169 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gp1bb glycoprotein Ib platelet subunit beta decreases expression EXP Methylene Chloride results in decreased expression of GP1BB mRNA CTD PMID:20955722 NCBI chr11:86,520,992...86,522,169
Ensembl chr11:86,520,992...86,522,169
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO [[Particulate Matter co-treated with Methylene Chloride] results in increased abundance of Polycyclic Aromatic Hydrocarbons] which affects the expression of GPX1 mRNA CTD PMID:29335169 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO [Lipopolysaccharides co-treated with Methylene Chloride] results in increased activity of GSR protein CTD PMID:15563889 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gstt1 glutathione S-transferase theta 1 affects metabolic processing
multiple interactions
increases metabolic processing
affects response to substance
ISO
EXP
GSTT1 gene polymorphism affects the metabolism of Methylene Chloride; GSTT1 protein affects the metabolism of Methylene Chloride
GSTT1 protein results in increased metabolism of and results in increased activity of Methylene Chloride
GSTT1 protein results in increased metabolism of Methylene Chloride
[GSTT1 protein affects the metabolism of Methylene Chloride] which results in increased abundance of Formaldehyde; GSTT1 protein affects the metabolism of and results in increased activity of Methylene Chloride
GSTT1 protein alternative form affects the susceptibility to Methylene Chloride
CTD PMID:7979958, PMID:8670055, PMID:8761485, PMID:9854036, PMID:10413528, PMID:11446825, PMID:11453994, PMID:12054768, PMID:14727918, PMID:15683365, PMID:16765633, PMID:17827337, PMID:20837120 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Herc1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 decreases expression EXP Methylene Chloride results in decreased expression of HERC1 mRNA CTD PMID:20955722 NCBI chr 8:72,029,550...72,198,363
Ensembl chr 8:72,029,489...72,198,358
JBrowse link
G Hes6 hes family bHLH transcription factor 6 increases expression ISO Methylene Chloride results in increased expression of HES6 mRNA CTD PMID:28392392 NCBI chr 9:98,549,698...98,551,438
Ensembl chr 9:98,549,705...98,551,438
JBrowse link
G Hivep2 HIVEP zinc finger 2 increases expression ISO Methylene Chloride results in increased expression of HIVEP2 mRNA CTD PMID:20359517 NCBI chr 1:8,129,354...8,333,890
Ensembl chr 1:8,310,577...8,333,885
JBrowse link
G Hlf HLF transcription factor, PAR bZIP family member increases expression ISO Methylene Chloride results in increased expression of HLF mRNA CTD PMID:28392392 NCBI chr10:77,836,352...77,918,656
Ensembl chr10:77,840,568...77,918,191
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO Methylene Chloride results in increased expression of HMOX1 mRNA
[[Particulate Matter co-treated with Methylene Chloride] results in increased abundance of Polycyclic Aromatic Hydrocarbons] which affects the expression of HMOX1 mRNA
[Particulate Matter co-treated with Methylene Chloride] results in increased expression of HMOX1 mRNA
CTD PMID:20359517, PMID:29335169, PMID:30503853 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnrnpll heterogeneous nuclear ribonucleoprotein L-like increases expression ISO Methylene Chloride results in increased expression of HNRNPLL mRNA CTD PMID:20359517 NCBI chr 6:2,698,983...2,729,715
Ensembl chr 6:2,699,961...2,729,394
JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 affects expression ISO Methylene Chloride affects the expression of HSD17B7 mRNA CTD PMID:28392392 NCBI chr13:88,288,116...88,308,019
Ensembl chr13:88,288,046...88,307,988
JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein decreases expression ISO Methylene Chloride results in decreased expression of ID3 mRNA CTD PMID:28392392 NCBI chr 5:154,489,603...154,491,172
Ensembl chr 5:154,489,590...154,491,223
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 affects expression ISO Methylene Chloride affects the expression of IDI1 mRNA CTD PMID:28392392 NCBI chr17:57,976,266...57,984,036
Ensembl chr17:57,976,268...57,984,036
JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 increases expression ISO Methylene Chloride results in increased expression of IFIT2 mRNA CTD PMID:20359517 NCBI chr 1:252,894,663...252,900,727
Ensembl chr 1:252,894,663...252,900,726
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 increases expression ISO Methylene Chloride results in increased expression of IFIT3 mRNA CTD PMID:20359517 NCBI chr 1:252,906,234...252,911,377
Ensembl chr 1:252,906,234...252,911,382
JBrowse link
G Ifng interferon gamma multiple interactions ISO [Methylene Chloride co-treated with Biliverdine] inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IFNG protein] CTD PMID:15486963 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ifngr2 interferon gamma receptor 2 increases expression ISO Methylene Chloride results in increased expression of IFNGR2 mRNA CTD PMID:20359517 NCBI chr11:31,694,339...31,712,611
Ensembl chr11:31,694,339...31,712,611
JBrowse link
G Il10 interleukin 10 multiple interactions ISO [Methylene Chloride co-treated with Biliverdine] inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL10 protein] CTD PMID:15486963 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [Particulate Matter co-treated with Methylene Chloride] results in increased expression of IL1A mRNA CTD PMID:30503853 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions ISO [[Particulate Matter co-treated with Methylene Chloride] results in increased abundance of Polycyclic Aromatic Hydrocarbons] which results in increased expression of IL1RN mRNA CTD PMID:29335169 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il2rg interleukin 2 receptor subunit gamma increases expression EXP Methylene Chloride results in increased expression of IL2RG mRNA CTD PMID:20955722 NCBI chr  X:71,165,378...71,169,078
Ensembl chr  X:71,162,585...71,169,865
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Methylene Chloride co-treated with Biliverdine] inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL6 protein] CTD PMID:15486963 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il7r interleukin 7 receptor decreases expression EXP Methylene Chloride results in decreased expression of IL7R mRNA CTD PMID:20955722
G Il9 interleukin 9 increases expression EXP Methylene Chloride results in increased expression of IL9 mRNA CTD PMID:20955722 NCBI chr17:8,558,827...8,561,950
Ensembl chr17:8,558,827...8,561,950
JBrowse link
G Irf5 interferon regulatory factor 5 decreases expression ISO Methylene Chloride results in decreased expression of IRF5 mRNA CTD PMID:28392392 NCBI chr 4:56,804,477...56,816,271
Ensembl chr 4:56,805,132...56,820,543
JBrowse link
G Irf6 interferon regulatory factor 6 decreases expression ISO Methylene Chloride results in decreased expression of IRF6 mRNA CTD PMID:28392392 NCBI chr13:111,870,121...111,889,328
Ensembl chr13:111,870,121...111,889,328
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO Methylene Chloride results in increased expression of JUN mRNA CTD PMID:28392392 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit increases expression ISO Methylene Chloride results in increased expression of JUNB mRNA CTD PMID:28392392 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G Klf13 Kruppel-like factor 13 decreases expression ISO Methylene Chloride results in decreased expression of KLF13 mRNA CTD PMID:28392392 NCBI chr 1:124,772,596...124,803,363
Ensembl chr 1:124,772,596...124,803,363
JBrowse link
G LOC100363405 hypothetical LOC100363405 increases expression ISO Methylene Chloride results in increased expression of ZFP37 mRNA CTD PMID:28392392 NCBI chr 5:77,265,335...77,294,739
Ensembl chr 5:77,266,842...77,294,765
JBrowse link
G LOC102547287 zinc finger protein 728-like increases expression ISO Methylene Chloride results in increased expression of ZFP58 mRNA CTD PMID:28392392 NCBI chr 1:37,927,069...37,939,418
Ensembl chr 1:37,928,102...37,932,084
JBrowse link
G Lss lanosterol synthase affects expression ISO Methylene Chloride affects the expression of LSS mRNA CTD PMID:28392392 NCBI chr20:12,844,522...12,870,474
Ensembl chr20:12,842,884...12,870,497
JBrowse link
G Mafb MAF bZIP transcription factor B increases expression ISO Methylene Chloride results in increased expression of MAFB mRNA CTD PMID:28392392 NCBI chr 3:156,338,993...156,340,913
Ensembl chr 3:156,339,004...156,340,913
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 increases expression ISO Methylene Chloride results in increased expression of MAP3K8 mRNA CTD PMID:20359517 NCBI chr17:56,109,403...56,129,925
Ensembl chr17:56,109,549...56,129,919
JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions ISO [Particulate Matter co-treated with Methylene Chloride] results in increased expression of MMP1 mRNA; carazolol inhibits the reaction [[Particulate Matter co-treated with Methylene Chloride] results in increased expression of MMP1 mRNA] CTD PMID:30503853 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mt2A metallothionein 2A multiple interactions ISO [[Particulate Matter co-treated with Methylene Chloride] results in increased abundance of Polycyclic Aromatic Hydrocarbons] which affects the expression of MT2 mRNA CTD PMID:29335169 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mvd mevalonate diphosphate decarboxylase affects expression ISO Methylene Chloride affects the expression of MVD mRNA CTD PMID:28392392 NCBI chr19:55,258,910...55,268,933
Ensembl chr19:55,258,905...55,268,951
JBrowse link
G Mvk mevalonate kinase affects expression ISO Methylene Chloride affects the expression of MVK mRNA CTD PMID:28392392 NCBI chr12:47,904,266...47,920,457
Ensembl chr12:47,904,719...47,919,400
JBrowse link
G Mxd1 max dimerization protein 1 increases expression ISO Methylene Chloride results in increased expression of MXD1 mRNA CTD PMID:20359517 NCBI chr 4:118,451,752...118,472,150
Ensembl chr 4:118,449,882...118,472,179
JBrowse link
G Mysm1 myb-like, SWIRM and MPN domains 1 decreases expression ISO Methylene Chloride results in decreased expression of MYSM1 mRNA CTD PMID:28392392 NCBI chr 5:113,902,115...113,939,083
Ensembl chr 5:113,906,803...113,939,127
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase decreases expression ISO Methylene Chloride results in decreased expression of NAMPT mRNA CTD PMID:28392392 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
JBrowse link
G Ncam1 neural cell adhesion molecule 1 decreases expression EXP Methylene Chloride results in decreased expression of NCAM1 mRNA CTD PMID:20955722 NCBI chr 8:53,836,797...54,134,881
Ensembl chr 8:53,839,098...53,901,358
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 increases expression ISO Methylene Chloride results in increased expression of NCF2 mRNA CTD PMID:20359517 NCBI chr13:70,226,441...70,259,019
Ensembl chr13:70,226,647...70,257,576
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 decreases expression ISO Methylene Chloride results in decreased expression of NCOR1 mRNA CTD PMID:28392392 NCBI chr10:48,629,121...48,772,890
Ensembl chr10:48,629,121...48,772,890
JBrowse link
G Nectin3 nectin cell adhesion molecule 3 decreases expression EXP Methylene Chloride results in decreased expression of NECTIN3 mRNA CTD PMID:20955722 NCBI chr11:57,897,879...57,995,193
Ensembl chr11:57,897,879...57,993,548
JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 increases expression ISO Methylene Chloride results in increased expression of NEDD9 mRNA CTD PMID:20359517 NCBI chr17:22,984,792...23,179,701
Ensembl chr17:22,984,844...23,179,701
JBrowse link
G Nfat5 nuclear factor of activated T-cells 5 increases expression ISO Methylene Chloride results in increased expression of NFAT5 mRNA CTD PMID:20359517 NCBI chr19:38,446,059...38,533,735
Ensembl chr19:38,446,059...38,533,735
JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 decreases expression EXP Methylene Chloride results in decreased expression of NFATC3 mRNA CTD PMID:20955722 NCBI chr19:38,039,542...38,114,003
Ensembl chr19:38,039,564...38,114,003
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases activity
multiple interactions
ISO Methylene Chloride results in increased activity of NFE2L2 protein
[[Particulate Matter co-treated with Methylene Chloride] results in increased abundance of Polycyclic Aromatic Hydrocarbons] which affects the expression of NFE2L2 mRNA
CTD PMID:29335169, PMID:30114225, PMID:30203046 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfib nuclear factor I/B increases expression ISO Methylene Chloride results in increased expression of NFIB mRNA CTD PMID:20359517 NCBI chr 5:100,436,343...100,647,962
Ensembl chr 5:100,439,082...100,647,727
JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated decreases expression ISO Methylene Chloride results in decreased expression of NFIL3 mRNA CTD PMID:28392392 NCBI chr17:12,261,102...12,276,316
Ensembl chr17:12,261,102...12,276,315
JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression ISO Methylene Chloride results in increased expression of NFKBIA mRNA CTD PMID:20359517 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO [[Particulate Matter co-treated with Methylene Chloride] results in increased abundance of Polycyclic Aromatic Hydrocarbons] which results in increased expression of NOS2 mRNA; Methylene Chloride inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Methylene Chloride inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:15563889, PMID:29335169 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Npas2 neuronal PAS domain protein 2 decreases expression ISO Methylene Chloride results in decreased expression of NPAS2 mRNA CTD PMID:28392392 NCBI chr 9:45,901,262...46,081,880
Ensembl chr 9:45,901,741...46,081,880
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [[Particulate Matter co-treated with Methylene Chloride] results in increased abundance of Polycyclic Aromatic Hydrocarbons] which affects the expression of NQO1 mRNA CTD PMID:29335169 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 increases expression ISO Methylene Chloride results in increased expression of NR1D1 mRNA CTD PMID:28392392 NCBI chr10:86,683,875...86,690,815
Ensembl chr10:86,683,875...86,690,815
JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 increases expression ISO Methylene Chloride results in increased expression of NR1D2 mRNA CTD PMID:28392392 NCBI chr15:8,730,871...8,757,165
Ensembl chr15:8,730,871...8,757,165
JBrowse link
G Nr2f6 nuclear receptor subfamily 2, group F, member 6 increases expression ISO Methylene Chloride results in increased expression of NR2F6 mRNA CTD PMID:28392392 NCBI chr16:19,769,968...19,777,414
Ensembl chr16:19,769,968...19,777,414
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases expression ISO Methylene Chloride results in decreased expression of NR3C1 mRNA CTD PMID:28392392 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nrdc nardilysin convertase decreases expression ISO Methylene Chloride results in decreased expression of NRD1 mRNA CTD PMID:28392392 NCBI chr 5:128,629,949...128,694,209
Ensembl chr 5:128,629,942...128,694,060
JBrowse link
G Onecut2 one cut homeobox 2 decreases expression ISO Methylene Chloride results in decreased expression of ONECUT2 mRNA CTD PMID:28392392 NCBI chr18:59,830,375...59,882,490
Ensembl chr18:59,830,363...59,875,127
JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 increases expression ISO Methylene Chloride results in increased expression of PELI1 mRNA CTD PMID:20359517 NCBI chr14:106,008,086...106,062,566
Ensembl chr14:106,008,086...106,061,641
JBrowse link
G Per3 period circadian regulator 3 increases expression ISO Methylene Chloride results in increased expression of PER3 mRNA CTD PMID:28392392 NCBI chr 5:168,088,126...168,123,482
Ensembl chr 5:168,086,998...168,123,395
JBrowse link
G Pf4 platelet factor 4 decreases expression EXP Methylene Chloride results in decreased expression of PF4 mRNA CTD PMID:20955722 NCBI chr14:18,848,549...18,849,258
Ensembl chr14:18,848,549...18,849,258
JBrowse link
G Pias1 protein inhibitor of activated STAT, 1 decreases expression ISO Methylene Chloride results in decreased expression of PIAS1 mRNA CTD PMID:28392392 NCBI chr 8:67,771,720...67,869,015
Ensembl chr 8:67,771,720...67,869,019
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO Methylene Chloride results in increased expression of PMAIP1 mRNA CTD PMID:20359517 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102
JBrowse link
G Pmvk phosphomevalonate kinase affects expression ISO Methylene Chloride affects the expression of PMVK mRNA CTD PMID:28392392 NCBI chr 2:188,784,329...188,793,890
Ensembl chr 2:188,784,222...188,793,895
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta decreases expression ISO Methylene Chloride results in decreased expression of PPARD mRNA CTD PMID:28392392 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha decreases expression ISO Methylene Chloride results in decreased expression of PPARGC1A mRNA CTD PMID:28392392 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Prnp prion protein increases expression ISO Methylene Chloride results in increased expression of PRNP mRNA CTD PMID:20359517 NCBI chr 3:124,515,917...124,531,320
Ensembl chr 3:124,515,978...124,531,316
JBrowse link
G Ptger2 prostaglandin E receptor 2 increases expression ISO Methylene Chloride results in increased expression of PTGER2 mRNA CTD PMID:20359517 NCBI chr15:19,336,029...19,349,759
Ensembl chr15:19,338,175...19,350,210
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [[Particulate Matter co-treated with Methylene Chloride] results in increased expression of PTGS2 mRNA]; [Particulate Matter co-treated with Methylene Chloride] results in increased expression of PTGS2 mRNA; carazolol inhibits the reaction [[Particulate Matter co-treated with Methylene Chloride] results in increased expression of PTGS2 mRNA] CTD PMID:30503853 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rab8b RAB8B, member RAS oncogene family increases expression ISO Methylene Chloride results in increased expression of RAB8B mRNA CTD PMID:20359517 NCBI chr 8:72,641,680...72,714,646
Ensembl chr 8:72,638,003...72,714,664
JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit increases expression ISO Methylene Chloride results in increased expression of RELB mRNA CTD PMID:20359517 NCBI chr 1:80,517,081...80,545,019
Ensembl chr 1:80,517,411...80,544,825
JBrowse link
G Rfx4 regulatory factor X4 decreases expression ISO Methylene Chloride results in decreased expression of RFX4 mRNA CTD PMID:28392392 NCBI chr 7:25,831,358...25,909,976
Ensembl chr 7:25,808,419...25,907,849
JBrowse link
G Rnf149 ring finger protein 149 increases expression ISO Methylene Chloride results in increased expression of RNF149 mRNA CTD PMID:20359517 NCBI chr 9:46,285,546...46,309,692
Ensembl chr 9:46,286,657...46,309,451
JBrowse link
G Rora RAR-related orphan receptor A decreases expression ISO Methylene Chloride results in decreased expression of RORA mRNA CTD PMID:28392392 NCBI chr 8:75,515,886...75,616,477
Ensembl chr 8:75,516,904...75,607,212
JBrowse link
G Rreb1 ras responsive element binding protein 1 decreases expression ISO Methylene Chloride results in decreased expression of RREB1 mRNA CTD PMID:28392392 NCBI chr17:27,539,137...27,718,878
Ensembl chr17:27,539,133...27,665,266
JBrowse link
G RT1-Ba RT1 class II, locus Ba increases expression EXP Methylene Chloride results in increased expression of RT1-BA mRNA CTD PMID:20955722 NCBI chr20:4,066,133...4,070,726
Ensembl chr20:4,066,132...4,070,721
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 increases expression EXP Methylene Chloride results in increased expression of RT1-DB1 mRNA CTD PMID:20955722 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190
JBrowse link
G RT1-DMb RT1 class II, locus DMb increases expression EXP Methylene Chloride results in increased expression of HLA-DMB mRNA CTD PMID:20955722 NCBI chr20:3,945,383...3,952,838
Ensembl chr20:5,227,045...5,234,290
JBrowse link
G Sall1 spalt-like transcription factor 1 decreases expression ISO Methylene Chloride results in decreased expression of SALL1 mRNA CTD PMID:28392392 NCBI chr19:23,387,737...23,405,025
Ensembl chr19:23,389,375...23,405,039
JBrowse link
G Sell selectin L increases expression EXP Methylene Chloride results in increased expression of SELL mRNA CTD PMID:20955722 NCBI chr13:82,369,820...82,387,774
Ensembl chr13:82,369,493...82,387,631
JBrowse link
G Serpinb2 serpin family B member 2 multiple interactions ISO [Particulate Matter co-treated with Methylene Chloride] results in increased expression of SERPINB2 mRNA CTD PMID:30503853 NCBI chr13:27,449,907...27,463,015
Ensembl chr13:27,449,934...27,463,010
JBrowse link
G Sesn2 sestrin 2 increases expression ISO Methylene Chloride results in increased expression of SESN2 mRNA CTD PMID:20359517 NCBI chr 5:150,684,891...150,703,846
Ensembl chr 5:150,684,133...150,704,117
JBrowse link
G Slc38a2 solute carrier family 38, member 2 increases expression ISO Methylene Chloride results in increased expression of SLC38A2 mRNA CTD PMID:20359517 NCBI chr 7:138,088,654...138,100,869
Ensembl chr 7:138,088,649...138,100,841
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Methylene Chloride results in increased expression of SLC7A11 mRNA CTD PMID:20359517 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO [[Particulate Matter co-treated with Methylene Chloride] results in increased abundance of Polycyclic Aromatic Hydrocarbons] which results in decreased expression of SOD1 mRNA CTD PMID:29335169 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO [[Particulate Matter co-treated with Methylene Chloride] results in increased abundance of Polycyclic Aromatic Hydrocarbons] which results in decreased expression of SOD2 mRNA CTD PMID:29335169 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sp3 Sp3 transcription factor increases expression ISO Methylene Chloride results in increased expression of SP3 mRNA CTD PMID:28392392 NCBI chr 3:59,644,579...59,689,011
Ensembl chr 3:59,646,015...59,688,692
JBrowse link
G Stat5a signal transducer and activator of transcription 5A decreases expression ISO Methylene Chloride results in decreased expression of STAT5A mRNA CTD PMID:28392392 NCBI chr10:88,764,732...88,789,060
Ensembl chr10:88,764,732...88,789,057
JBrowse link
G Stat5b signal transducer and activator of transcription 5B decreases expression
increases activity
ISO Methylene Chloride results in decreased expression of STAT5B mRNA
Methylene Chloride results in increased activity of STAT5B protein
CTD PMID:28392392, PMID:30114225 NCBI chr10:88,686,207...88,712,313
Ensembl chr10:88,686,207...88,754,829
JBrowse link
G Stx11 syntaxin 11 increases expression ISO Methylene Chloride results in increased expression of STX11 mRNA CTD PMID:20359517 NCBI chr 1:7,039,160...7,064,870
Ensembl chr 1:7,039,162...7,064,870
JBrowse link
G Tef TEF transcription factor, PAR bZIP family member increases expression ISO Methylene Chloride results in increased expression of TEF mRNA CTD PMID:28392392 NCBI chr 7:123,033,971...123,058,606
Ensembl chr 7:123,043,503...123,058,604
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Methylene Chloride co-treated with Biliverdine] inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of TNF protein] CTD PMID:15486963 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 increases expression ISO Methylene Chloride results in increased expression of TNFAIP3 mRNA CTD PMID:20359517 NCBI chr 1:14,401,103...14,416,369
Ensembl chr 1:14,402,913...14,412,807
JBrowse link
G Trip12 thyroid hormone receptor interactor 12 decreases expression EXP Methylene Chloride results in decreased expression of TRIP12 mRNA CTD PMID:20955722 NCBI chr 9:92,305,059...92,435,388
Ensembl chr 9:92,305,051...92,435,365
JBrowse link
G Trps1 transcriptional repressor GATA binding 1 increases expression ISO Methylene Chloride results in increased expression of TRPS1 mRNA CTD PMID:28392392 NCBI chr 7:90,085,895...90,320,430
Ensembl chr 7:90,090,828...90,318,221
JBrowse link
G Usp18 ubiquitin specific peptidase 18 increases expression ISO Methylene Chloride results in increased expression of USP18 mRNA CTD PMID:20359517 NCBI chr 4:153,812,312...153,834,374
Ensembl chr 4:153,805,993...153,834,430
JBrowse link
G Wee1 WEE1 G2 checkpoint kinase increases expression ISO Methylene Chloride results in increased expression of WEE1 mRNA CTD PMID:28392392 NCBI chr 1:174,765,228...174,790,882
Ensembl chr 1:174,767,960...174,786,361
JBrowse link
G Wwp1 WW domain containing E3 ubiquitin protein ligase 1 decreases expression EXP Methylene Chloride results in decreased expression of WWP1 mRNA CTD PMID:20955722 NCBI chr 5:33,608,489...33,696,487
Ensembl chr 5:33,609,136...33,664,435
JBrowse link
G Xbp1 X-box binding protein 1 increases expression ISO Methylene Chloride results in increased expression of XBP1 mRNA CTD PMID:20359517 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
G Zbtb22 zinc finger and BTB domain containing 22 decreases expression ISO Methylene Chloride results in decreased expression of ZBTB22 mRNA CTD PMID:28392392 NCBI chr20:5,476,345...5,479,900
Ensembl chr20:5,476,345...5,479,511
JBrowse link
G Zbtb41 zinc finger and BTB domain containing 41 decreases expression ISO Methylene Chloride results in decreased expression of ZBTB41 mRNA CTD PMID:28392392 NCBI chr13:56,513,231...56,542,444
Ensembl chr13:56,513,286...56,537,142
JBrowse link
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 increases expression ISO Methylene Chloride results in increased expression of ZC3HAV1 mRNA CTD PMID:20359517 NCBI chr 4:66,012,111...66,062,160
Ensembl chr 4:66,011,915...66,062,089
JBrowse link
G Zcchc2 zinc finger CCHC-type containing 2 increases expression ISO Methylene Chloride results in increased expression of ZCCHC2 mRNA CTD PMID:20359517 NCBI chr13:25,961,762...26,052,472
Ensembl chr13:25,966,428...26,013,338
JBrowse link
G Zfhx4 zinc finger homeobox 4 decreases expression ISO Methylene Chloride results in decreased expression of ZFHX4 mRNA CTD PMID:28392392 NCBI chr 2:98,423,565...98,610,368
Ensembl chr 2:98,423,569...98,610,368
JBrowse link
G Zfp260 zinc finger protein 260 affects expression
increases expression
ISO Methylene Chloride affects the expression of ZFP260 mRNA
Methylene Chloride results in increased expression of ZFP260 mRNA
CTD PMID:28392392 NCBI chr 1:88,452,133...88,465,110
Ensembl chr 1:88,451,958...88,453,578
Ensembl chr 1:88,451,958...88,453,578
JBrowse link
G Zfp266 zinc finger protein 266 decreases expression ISO Methylene Chloride results in decreased expression of ZFP266 mRNA CTD PMID:28392392 NCBI chr 8:21,511,831...21,543,275
Ensembl chr 8:21,511,839...21,523,540
JBrowse link
G Zfp386 zinc finger protein 386 (Kruppel-like) increases expression ISO Methylene Chloride results in increased expression of ZFP386 mRNA CTD PMID:28392392 NCBI chr 6:143,901,239...143,915,953
Ensembl chr 6:143,901,280...143,917,575
JBrowse link
G Zfp445 zinc finger protein 445 increases expression ISO Methylene Chloride results in increased expression of ZFP445 mRNA CTD PMID:28392392 NCBI chr 8:131,885,119...131,904,303
Ensembl chr 8:131,888,047...131,899,023
JBrowse link
G Zfp451 zinc finger protein 451 decreases expression ISO Methylene Chloride results in decreased expression of ZFP451 mRNA CTD PMID:28392392 NCBI chr 9:38,395,464...38,451,585
Ensembl chr 9:38,396,449...38,451,656
JBrowse link
G Zfp472 zinc finger protein 472 increases expression ISO Methylene Chloride results in increased expression of ZFP119A mRNA CTD PMID:28392392 NCBI chr 7:15,242,149...15,250,418
Ensembl chr 7:15,242,227...15,250,411
JBrowse link
G Zfp62 zinc finger protein 62 increases expression ISO Methylene Chloride results in increased expression of ZFP62 mRNA CTD PMID:28392392 NCBI chr10:34,477,108...34,493,941
Ensembl chr10:34,489,940...34,493,088
JBrowse link
G Zfp647 zinc finger protein 647 decreases expression ISO Methylene Chloride results in decreased expression of ZFP647 mRNA CTD PMID:28392392 NCBI chr 7:118,513,063...118,528,454
Ensembl chr 7:118,513,684...118,518,193
JBrowse link
G Zfp74 zinc finger protein 74 increases expression ISO Methylene Chloride results in increased expression of ZFP74 mRNA CTD PMID:28392392 NCBI chr 1:88,231,016...88,257,565
Ensembl chr 1:88,232,617...88,240,057
JBrowse link
G Zhx1 zinc fingers and homeoboxes 1 affects expression
increases expression
ISO Methylene Chloride affects the expression of ZHX1 mRNA
Methylene Chloride results in increased expression of ZHX1 mRNA
CTD PMID:28392392 NCBI chr 7:97,915,280...97,944,787
Ensembl chr 7:97,915,581...97,944,491
JBrowse link
G Zmat1 zinc finger, matrin-type 1 increases expression ISO Methylene Chloride results in increased expression of ZMAT1 mRNA CTD PMID:28392392 NCBI chr  X:105,804,603...105,836,410
Ensembl chr  X:105,805,902...105,835,327
JBrowse link
G Znf354b zinc finger protein 354B increases expression ISO Methylene Chloride results in increased expression of ZFP354B mRNA CTD PMID:28392392 NCBI chr10:36,411,730...36,423,346
Ensembl chr10:36,411,963...36,419,926
JBrowse link
G Zscan12 zinc finger and SCAN domain containing 12 decreases expression ISO Methylene Chloride results in decreased expression of ZSCAN12 mRNA CTD PMID:28392392 NCBI chr17:45,279,171...45,285,069
Ensembl chr17:45,279,162...45,285,060
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      application 19426
        refrigerant 17439
          dichloromethane 184
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    main group molecular entity 19702
                      s-block molecular entity 19461
                        hydrogen molecular entity 19452
                          hydrides 18707
                            organic hydride 18269
                              organic fundamental parent 18269
                                hydrocarbon 17988
                                  halohydrocarbon 13956
                                    haloalkane 11674
                                      chloroalkane 9140
                                        chloromethanes 7273
                                          dichloromethane 184
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.