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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:beta-D-glucose
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Accession:CHEBI:15903 term browser browse the term
Definition:D-Glucopyranose with beta configuration at the anomeric centre.
Synonyms:related_synonym: Formula=C6H12O6;   InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6-/m1/s1;   InChIKey=WQZGKKKJIJFFOK-VFUOTHLCSA-N;   SMILES=OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O;   beta-D-Glucopyranose
 alt_id: CHEBI:10397;   CHEBI:12373;   CHEBI:22795;   CHEBI:41140
 xref: Beilstein:1281607;   CAS:492-61-5;   DrugBank:DB02379;   Drug_Central:845;   GlyTouCan:G71142DF;   Gmelin:648637;   KEGG:C00221;   PDBeChem:BGC;   PMID:19443021;   PMID:25568069;   PMID:31537530;   Reaxys:1281607
 cyclic_relationship: is_enantiomer_of CHEBI:37631


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(+)-syringaresinol beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of ACHE protein] CTD PMID:31077737 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO [acanthoside B co-treated with Scopolamine] results in increased expression of BDNF protein CTD PMID:31077737 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Cat catalase multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in decreased activity of CAT protein] CTD PMID:31077737 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in decreased phosphorylation of CREB1 protein] CTD PMID:31077737 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Il10 interleukin 10 multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in decreased expression of IL10 protein] CTD PMID:31077737 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of IL1B protein] CTD PMID:31077737 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of IL6 protein] CTD PMID:31077737 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of NOS2 protein] CTD PMID:31077737 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 multiple interactions ISO [acanthoside B co-treated with Scopolamine] results in increased phosphorylation of NTRK2 protein CTD PMID:31077737 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of PTGS2 protein] CTD PMID:31077737 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of TNF protein] CTD PMID:31077737 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
(20S)-ginsenoside Rh1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO ginsenoside Rh1 results in increased expression of FOS mRNA CTD PMID:16204943 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:21875580 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO ginsenoside Rh1 inhibits the reaction [Oxazolone results in increased expression of IL1B mRNA]; ginsenoside Rh1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA] CTD PMID:16557482 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il4 interleukin 4 decreases expression ISO ginsenoside Rh1 results in decreased expression of IL4 CTD PMID:22855946 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 multiple interactions ISO ginsenoside Rh1 inhibits the reaction [Galactose results in increased secretion of IL6 protein] CTD PMID:29412148 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Itga4 integrin subunit alpha 4 multiple interactions ISO ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGA4 protein binds to ITGB1 protein]] CTD PMID:21875580 NCBI chr 3:66,178,745...66,265,547
Ensembl chr 3:66,193,059...66,263,960
JBrowse link
G Itgal integrin subunit alpha L multiple interactions ISO ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGAL protein binds to ITGB2 protein]] CTD PMID:21875580 NCBI chr 1:198,744,053...198,781,745
Ensembl chr 1:198,744,050...198,781,750
JBrowse link
G Itgb1 integrin subunit beta 1 multiple interactions ISO ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGA4 protein binds to ITGB1 protein]] CTD PMID:21875580 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Itgb2 integrin subunit beta 2 multiple interactions ISO ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGAL protein binds to ITGB2 protein]] CTD PMID:21875580 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases activity ISO ginsenoside Rh1 results in decreased activity of JUN protein CTD PMID:22855946 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Lpl lipoprotein lipase increases secretion ISO ginsenoside Rh1 results in increased secretion of LPL protein CTD PMID:8988629 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Pgr progesterone receptor increases expression ISO ginsenoside Rh1 results in increased expression of PGR protein CTD PMID:16204943 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO ginsenoside Rh1 inhibits the reaction [Oxazolone results in increased expression of PTGS2 mRNA]; ginsenoside Rh1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA] CTD PMID:16557482 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Sele selectin E multiple interactions ISO ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of SELE protein] CTD PMID:21875580 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341
JBrowse link
G Tff1 trefoil factor 1 increases expression ISO ginsenoside Rh1 results in increased expression of TFF1 mRNA CTD PMID:16204943 NCBI chr20:9,892,124...9,895,984
Ensembl chr20:9,892,124...9,895,984
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
decreases response to substance
ISO ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGA4 protein binds to ITGB1 protein]]; ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGAL protein binds to ITGB2 protein]]; ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of SELE protein]; ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]
ginsenoside Rh1 inhibits the reaction [Oxazolone results in increased expression of TNF mRNA]; ginsenoside Rh1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]
ginsenoside Rh1 results in decreased expression of TNF
ginsenoside Rh1 results in decreased susceptibility to TNF protein
CTD PMID:16557482, PMID:21875580, PMID:22855946 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] CTD PMID:21875580 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
(20S)-ginsenoside Rh2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO ginsenoside Rh2 results in increased expression of BAX protein CTD PMID:26482938 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO ginsenoside Rh2 results in decreased expression of BCL2 protein CTD PMID:26482938 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 increases cleavage ISO ginsenoside Rh2 results in increased cleavage of CASP3 protein CTD PMID:26482938 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO ginsenoside Rh2 results in decreased expression of CCND1 protein CTD PMID:26482938 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Hdac1 histone deacetylase 1 decreases expression ISO ginsenoside Rh2 results in decreased expression of HDAC1 protein CTD PMID:26482938 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Hdac2 histone deacetylase 2 decreases expression ISO ginsenoside Rh2 results in decreased expression of HDAC2 protein CTD PMID:26482938 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198
JBrowse link
G Hdac6 histone deacetylase 6 decreases expression ISO ginsenoside Rh2 results in decreased expression of HDAC6 protein CTD PMID:26482938 NCBI chr  X:15,295,372...15,316,673
Ensembl chr  X:15,295,473...15,316,671
JBrowse link
G Il6 interleukin 6 multiple interactions ISO ginsenoside Rh2 inhibits the reaction [Galactose results in increased secretion of IL6 protein] CTD PMID:29412148 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation ISO ginsenoside Rh2 results in decreased phosphorylation of MAPK1 protein CTD PMID:26482938 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation ISO ginsenoside Rh2 results in decreased phosphorylation of MAPK3 protein CTD PMID:26482938 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of ACACA mRNA] CTD PMID:30721698 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]
beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased expression of CCL2 protein]
CTD PMID:16253226, PMID:30721698 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of CEBPA mRNA]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of CEBPA protein] CTD PMID:30721698 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FAS mRNA] CTD PMID:30721698 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA] CTD PMID:16253226 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Il6 interleukin 6 multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased expression of IL6 protein] CTD PMID:30721698 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ins2 insulin 2 multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of ACACA mRNA]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of CEBPA mRNA]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of CEBPA protein]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FAS mRNA]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG mRNA]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG protein]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SCD1 mRNA]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SCD1 protein]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 protein]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased phosphorylation of MAPK1 protein]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased phosphorylation of MAPK3 protein]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased phosphorylation of MAPK8 protein]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased phosphorylation of MAPK9 protein] CTD PMID:30721698 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased phosphorylation of MAPK1 protein]; beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein] CTD PMID:30721698 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased phosphorylation of MAPK3 protein]; beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein] CTD PMID:30721698 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased phosphorylation of MAPK8 protein]; beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased phosphorylation of MAPK8 protein] CTD PMID:30721698 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased phosphorylation of MAPK9 protein]; beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased phosphorylation of MAPK9 protein] CTD PMID:30721698 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG mRNA]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG protein] CTD PMID:30721698 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased localization of RELA protein] CTD PMID:16253226 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SCD1 mRNA]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SCD1 protein] CTD PMID:30721698 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]; beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 protein] CTD PMID:30721698 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased localization of RELA protein]
beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased expression of CCL2 protein]; beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased expression of IL6 protein]; beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]; beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased phosphorylation of MAPK8 protein]; beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased phosphorylation of MAPK9 protein]
CTD PMID:16253226, PMID:30721698 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA] CTD PMID:16253226 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
4-methylumbelliferyl beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gaa glucosidase, alpha, acid multiple interactions
increases metabolic processing
ISO GAA gene SNP inhibits the reaction [GAA protein results in increased metabolism of 4-methylumbelliferyl glucoside] CTD PMID:21963784 NCBI chr10:108,395,873...108,412,999
Ensembl chr10:108,395,860...108,413,059
JBrowse link
albiflorin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 affects expression EXP albiflorin affects the expression of DRD2 CTD PMID:26475043 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A affects expression EXP albiflorin affects the expression of HTR1A CTD PMID:26475043 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A affects expression EXP albiflorin affects the expression of HTR2A CTD PMID:26475043 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Slc6a3 solute carrier family 6 member 3 affects expression EXP albiflorin affects the expression of SLC6A3 CTD PMID:26475043 NCBI chr 1:32,323,011...32,363,983
Ensembl chr 1:32,321,580...32,363,983
JBrowse link
G Th tyrosine hydroxylase affects expression EXP albiflorin affects the expression of TH CTD PMID:26475043 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
asperuloside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnf tumor necrosis factor multiple interactions ISO asperuloside inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:16508180 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nos2 nitric oxide synthase 2 multiple interactions ISO ganglioside, GD1b analog inhibits the reaction [[lipopolysaccharide, E. coli O26-B6 results in increased activity of NOS2 protein] which results in increased secretion of Nitrites]; ganglioside, GD1b inhibits the reaction [[lipopolysaccharide, E. coli O26-B6 results in increased activity of NOS2 protein] which results in increased secretion of Nitrites] CTD PMID:31202640 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
beta-D-glucosamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aacs acetoacetyl-CoA synthetase increases expression ISO Glucosamine results in increased expression of AACS mRNA CTD PMID:17178593 NCBI chr12:36,512,393...36,555,694
Ensembl chr12:36,512,393...36,555,694
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 increases expression EXP Glucosamine results in increased expression of ABCG1 mRNA CTD PMID:17109745 NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489
JBrowse link
G Acaca acetyl-CoA carboxylase alpha increases expression ISO Glucosamine results in increased expression of ACACA mRNA CTD PMID:22096489 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Acan aggrecan multiple interactions
increases expression
decreases expression
affects expression
ISO
EXP
Glucosamine analog affects the reaction [IL1B results in decreased expression of ACAN mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of ACAN mRNA]; Glucosamine results in decreased cleavage of and results in decreased secretion of ACAN protein
Glucosamine results in increased expression of ACAN mRNA
Glucosamine inhibits the reaction [IL1B results in decreased expression of ACAN mRNA]
Glucosamine analog results in increased expression of ACAN protein; Glucosamine results in increased expression of ACAN mRNA; Glucosamine results in increased expression of ACAN protein
Glucosamine analog results in decreased expression of ACAN mRNA
Glucosamine analog affects the expression of ACAN mRNA
CTD PMID:12801482, PMID:16300972, PMID:16872674, PMID:17109745, PMID:17337215, PMID:18321735, PMID:19909832 NCBI chr 1:140,762,758...140,824,441
Ensembl chr 1:140,762,758...140,824,441
JBrowse link
G Acot1 acyl-CoA thioesterase 1 increases expression ISO Glucosamine results in increased expression of ACOT1 mRNA CTD PMID:17178593 NCBI chr 6:107,485,088...107,493,082
Ensembl chr 6:107,485,249...107,493,798
JBrowse link
G Acox2 acyl-CoA oxidase 2 decreases expression ISO Glucosamine results in decreased expression of ACOX2 mRNA CTD PMID:17178593 NCBI chr15:18,449,304...18,481,472
Ensembl chr15:18,451,144...18,481,470
JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 increases expression ISO Glucosamine results in increased expression of ACSS2 mRNA CTD PMID:17178593 NCBI chr 3:151,032,925...151,075,856
Ensembl chr 3:151,032,952...151,075,856
JBrowse link
G Adam15 ADAM metallopeptidase domain 15 multiple interactions
decreases expression
EXP Glucosamine affects the reaction [IL1B results in decreased expression of ADAM15 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of ADAM15 mRNA] CTD PMID:17109745 NCBI chr 2:188,661,831...188,672,337
Ensembl chr 2:188,661,699...188,672,247
JBrowse link
G Adam17 ADAM metallopeptidase domain 17 multiple interactions
increases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of ADAM17 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of ADAM17 mRNA] CTD PMID:17109745 NCBI chr 6:43,400,525...43,448,280
Ensembl chr 6:43,400,528...43,448,280
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 decreases expression
multiple interactions
ISO
EXP
Glucosamine analog results in decreased expression of ADAMTS1 mRNA
Glucosamine results in decreased expression of ADAMTS1 mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of ADAMTS1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of ADAMTS1 mRNA]
CTD PMID:16300972, PMID:17109745 NCBI chr11:25,342,119...25,350,938
Ensembl chr11:25,342,126...25,350,974
JBrowse link
G Adamts20 ADAM metallopeptidase with thrombospondin type 1 motif, 20 decreases cleavage ISO Glucosamine results in decreased cleavage of ADAMTS20 protein alternative form CTD PMID:19909832 NCBI chr 7:135,465,021...135,630,941
Ensembl chr 7:135,466,884...135,630,654
JBrowse link
G Adamts4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 increases expression EXP Glucosamine results in increased expression of ADAMTS4 mRNA CTD PMID:17109745 NCBI chr13:89,622,996...89,632,485
Ensembl chr13:89,622,632...89,634,419
JBrowse link
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 decreases expression
multiple interactions
ISO Glucosamine analog results in decreased expression of ADAMTS5 mRNA
Glucosamine results in decreased cleavage of and results in decreased activity of ADAMTS5 protein alternative form
CTD PMID:16300972, PMID:19909832 NCBI chr11:25,411,174...25,456,639
Ensembl chr11:25,410,975...25,456,836
JBrowse link
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 decreases cleavage ISO Glucosamine results in decreased cleavage of ADAMTS9 protein alternative form CTD PMID:19909832 NCBI chr 4:124,660,254...124,860,997
Ensembl chr 4:124,660,262...124,858,250
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases expression ISO
EXP
Glucosamine results in increased expression of ADIPOQ mRNA CTD PMID:15694357 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Afp alpha-fetoprotein increases expression ISO Glucosamine results in increased expression of AFP mRNA CTD PMID:17178593 NCBI chr14:19,141,755...19,159,919
Ensembl chr14:19,141,755...19,159,923
JBrowse link
G Agt angiotensinogen increases expression ISO Glucosamine results in increased expression of AGT mRNA CTD PMID:17178593 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Ahi1 Abelson helper integration site 1 decreases expression ISO Glucosamine results in decreased expression of AHI1 mRNA CTD PMID:17178593 NCBI chr 1:16,478,127...16,601,769
Ensembl chr 1:16,478,127...16,601,769
JBrowse link
G Akr1b8 aldo-keto reductase family 1, member B8 increases expression EXP Glucosamine results in increased expression of AKR1B8 mRNA CTD PMID:17109745 NCBI chr 4:61,772,064...61,784,637
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akt1 AKT serine/threonine kinase 1 affects phosphorylation
multiple interactions
ISO Glucosamine analog affects the phosphorylation of AKT1 protein
Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]]
Glucosamine analog affects the reaction [IL1B results in increased phosphorylation of AKT1 protein]; Glucosamine promotes the reaction [IL1B results in increased phosphorylation of AKT1 protein]
CTD PMID:18080321, PMID:18340449, PMID:30602124 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alg12 ALG12, alpha-1,6-mannosyltransferase decreases expression ISO Glucosamine results in decreased expression of ALG12 mRNA CTD PMID:17178593 NCBI chr 7:129,798,663...129,812,677
Ensembl chr 7:129,798,663...129,812,388
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions
increases expression
increases activity
ISO 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased activity of ALPL protein]
Glucosamine analog results in increased expression of ALPL mRNA
CTD PMID:20458730 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Apoa1 apolipoprotein A1 increases secretion
increases stability
ISO Glucosamine results in increased secretion of APOA1 protein
Glucosamine results in increased stability of APOA1 mRNA
CTD PMID:15164326 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apob apolipoprotein B multiple interactions
increases degradation
increases ubiquitination
decreases secretion
decreases localization
decreases expression
ISO
EXP
acetylleucyl-leucyl-norleucinal inhibits the reaction [Glucosamine results in decreased expression of and results in decreased secretion of APOB protein]; Glucosamine results in decreased expression of and results in decreased secretion of APOB protein; Oleic Acid inhibits the reaction [Glucosamine results in decreased secretion of APOB protein]
Oleic Acid inhibits the reaction [Glucosamine results in increased degradation of APOB protein]
Glucosamine results in increased ubiquitination of APOB protein
Glucosamine results in decreased localization of APOB protein
Glucosamine results in decreased expression of APOB protein
CTD PMID:15618547, PMID:19383982 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Apoe apolipoprotein E multiple interactions ISO [Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine; INS1 inhibits the reaction [[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine] CTD PMID:16380481 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like decreases expression ISO Glucosamine results in decreased expression of ARNTL mRNA; Glucosamine results in decreased expression of ARNTL protein CTD PMID:24442997 NCBI chr 1:178,039,002...178,137,469
Ensembl chr 1:178,039,063...178,137,465
JBrowse link
G Ass1 argininosuccinate synthase 1 multiple interactions EXP Glucosamine inhibits the reaction [IL1B results in increased expression of ASS1 mRNA] CTD PMID:17109745 NCBI chr 3:10,327,411...10,375,847
Ensembl chr 3:10,327,414...10,375,826
JBrowse link
G Atf3 activating transcription factor 3 decreases expression ISO Glucosamine results in decreased expression of ATF3 mRNA CTD PMID:17178593 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atf4 activating transcription factor 4 increases expression
multiple interactions
ISO Glucosamine results in increased expression of ATF4 mRNA; Glucosamine results in increased expression of ATF4 protein
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF4 protein]; EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of ATF4 mRNA]; GSK2656157 inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA]
CTD PMID:30602124 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions
increases expression
decreases expression
ISO
EXP
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; tauroursodeoxycholic acid inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]
Glucosamine results in increased expression of ATF6 protein
ATF6 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]
Glucosamine results in decreased expression of ATF6 mRNA
CTD PMID:17178593, PMID:19383982, PMID:20165829, PMID:30602124 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443
JBrowse link
G Atf7ip activating transcription factor 7 interacting protein increases expression ISO Glucosamine results in increased expression of ATF7IP mRNA CTD PMID:17178593 NCBI chr 4:170,476,998...170,563,063
Ensembl chr 4:170,518,673...170,559,532
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 decreases expression ISO Glucosamine results in decreased expression of ATP2A2 mRNA CTD PMID:17178593 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326
JBrowse link
G Azin1 antizyme inhibitor 1 decreases expression
multiple interactions
EXP Glucosamine results in decreased expression of AZIN1 mRNA
IL1B promotes the reaction [Glucosamine results in increased expression of AZIN1 mRNA]
CTD PMID:17109745 NCBI chr 7:77,345,646...77,372,398
Ensembl chr 7:77,345,646...77,372,398
JBrowse link
G B3gat3 beta-1,3-glucuronyltransferase 3 multiple interactions
increases expression
EXP [XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucosamine results in increased expression of B3GAT3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased activity of B3GAT3 protein]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of B3GAT3 mRNA] CTD PMID:11229466, PMID:11801247 NCBI chr 1:225,120,061...225,126,579
Ensembl chr 1:225,120,061...225,126,579
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression
multiple interactions
ISO Glucosamine results in decreased expression of BCL2L1 protein
pepstatin inhibits the reaction [Glucosamine results in decreased expression of BCL2L1 protein]
CTD PMID:15972124, PMID:16850161 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bdnf brain-derived neurotrophic factor decreases expression ISO Glucosamine results in decreased expression of BDNF mRNA CTD PMID:17178593 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Bglap bone gamma-carboxyglutamate protein increases expression ISO Glucosamine analog results in increased expression of BGLAP mRNA CTD PMID:20458730 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Bgn biglycan multiple interactions
decreases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of BGN mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of BGN mRNA] CTD PMID:17109745 NCBI chr  X:157,319,042...157,331,204
Ensembl chr  X:157,319,046...157,331,204
JBrowse link
G Bmp2 bone morphogenetic protein 2 multiple interactions EXP Glucosamine inhibits the reaction [IL1B results in increased expression of BMP2 mRNA] CTD PMID:17109745 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Bmp4 bone morphogenetic protein 4 decreases expression
multiple interactions
EXP Glucosamine results in decreased expression of BMP4 mRNA
Glucosamine promotes the reaction [IL1B results in decreased expression of BMP4 mRNA]
CTD PMID:17109745 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions
decreases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of BMP6 mRNA]
Glucosamine results in decreased expression of BMP6 mRNA
CTD PMID:17109745 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Bmp7 bone morphogenetic protein 7 multiple interactions
increases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of BMP7 mRNA]
Glucosamine results in increased expression of BMP7 mRNA
CTD PMID:17109745 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399
JBrowse link
G Ca3 carbonic anhydrase 3 decreases expression EXP Glucosamine results in decreased expression of CAR3 mRNA CTD PMID:17109745 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410
JBrowse link
G Calr calreticulin decreases expression ISO Glucosamine results in decreased expression of CALR mRNA CTD PMID:17178593 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
ISO Glucosamine results in increased cleavage of CASP3 protein
Glucosamine results in increased activity of and results in increased cleavage of CASP3 protein
CTD PMID:16850161, PMID:22020377 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp4 caspase 4 decreases expression ISO Glucosamine results in decreased expression of CASP4 mRNA CTD PMID:17178593 NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652
JBrowse link
G Cbr3 carbonyl reductase 3 increases expression ISO Glucosamine results in increased expression of CBR3 mRNA CTD PMID:17178593 NCBI chr11:33,909,417...33,917,674
Ensembl chr11:33,909,439...33,917,674
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression
ISO
EXP
Alloxan inhibits the reaction [Glucosamine inhibits the reaction [CAP18 lipopolysaccharide-binding protein results in increased expression of CCL2 protein]]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL2 protein]; Glucosamine inhibits the reaction [CAP18 lipopolysaccharide-binding protein results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [CAP18 lipopolysaccharide-binding protein results in increased expression of CCL2 protein]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 protein]
Glucosamine results in increased expression of CCL2 mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of CCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL2 mRNA]
CTD PMID:17109745, PMID:18080321, PMID:18949387, PMID:19020780 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 multiple interactions
increases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of CCL20 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL20 mRNA] CTD PMID:17109745 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
JBrowse link
G Ccl22 C-C motif chemokine ligand 22 multiple interactions EXP Glucosamine inhibits the reaction [IL1B results in increased expression of CCL22 mRNA] CTD PMID:17109745 NCBI chr19:10,674,189...10,681,145
Ensembl chr19:10,674,189...10,681,145
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions EXP Glucosamine inhibits the reaction [IL1B results in increased expression of CCL3 mRNA] CTD PMID:17109745 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO
EXP
Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL5 protein]
Glucosamine inhibits the reaction [IL1B results in increased expression of CCL5 mRNA]
CTD PMID:17109745, PMID:18080321 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 multiple interactions
increases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of CCL7 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL7 mRNA] CTD PMID:17109745 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
JBrowse link
G Ccn2 cellular communication network factor 2 increases expression EXP Glucosamine analog results in increased expression of CCN2 mRNA CTD PMID:21466783 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccnb1 cyclin B1 decreases expression EXP Glucosamine results in decreased expression of CCNB1 mRNA CTD PMID:17109745 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Cd24 CD24 molecule increases expression ISO Glucosamine results in increased expression of CD24A mRNA CTD PMID:17178593 NCBI chr20:48,335,540...48,340,847
Ensembl chr20:48,335,540...48,340,846
JBrowse link
G Cd28 Cd28 molecule increases expression EXP Glucosamine results in increased expression of CD28 mRNA CTD PMID:17109745 NCBI chr 9:67,546,408...67,573,858
Ensembl chr 9:67,546,408...67,571,871
JBrowse link
G Cdc20 cell division cycle 20 decreases expression EXP Glucosamine results in decreased expression of CDC20 mRNA CTD PMID:17109745 NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015
JBrowse link
G Cdc23 cell division cycle 23 decreases expression EXP Glucosamine results in decreased expression of CDC23 mRNA CTD PMID:17109745 NCBI chr18:27,430,924...27,452,569
Ensembl chr18:27,430,905...27,452,420
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression EXP Glucosamine results in decreased expression of CDK1 mRNA CTD PMID:17109745 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP
ISO
Glucosamine results in increased expression of CDKN1A protein
Glucosamine results in increased expression of CDKN1A mRNA
CTD PMID:15654767, PMID:17178593 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B decreases expression EXP Glucosamine results in decreased expression of CDKN1B protein CTD PMID:15654767 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression EXP Glucosamine results in decreased expression of CDKN3 mRNA CTD PMID:17109745 NCBI chr15:23,553,171...23,564,538
Ensembl chr15:23,553,128...23,564,535
JBrowse link
G Cenpf centromere protein F decreases expression EXP Glucosamine results in decreased expression of CENPF mRNA CTD PMID:17109745 NCBI chr13:108,132,499...108,178,609
Ensembl chr13:108,132,499...108,178,609
JBrowse link
G Chi3l1 chitinase 3 like 1 decreases expression ISO Glucosamine analog results in decreased expression of CHI3L1 mRNA CTD PMID:16142878 NCBI chr13:51,022,844...51,030,797
Ensembl chr13:51,022,681...51,030,802
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions
decreases activity
ISO Glucosamine analog results in decreased activity of and results in decreased localization of CHUK protein
Glucosamine analog results in decreased activity of CHUK protein
CTD PMID:20113495 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169
JBrowse link
G Ckap2 cytoskeleton associated protein 2 decreases expression EXP Glucosamine results in decreased expression of CKAP2 mRNA CTD PMID:17109745 NCBI chr16:74,752,655...74,779,184
Ensembl chr16:74,752,655...74,779,184
JBrowse link
G Clock clock circadian regulator decreases expression ISO Glucosamine results in decreased expression of CLOCK mRNA; Glucosamine results in decreased expression of CLOCK protein CTD PMID:24442997 NCBI chr14:34,418,226...34,502,218
Ensembl chr14:34,446,616...34,502,218
JBrowse link
G Clta clathrin, light chain A decreases expression EXP Glucosamine results in decreased expression of CLTA mRNA CTD PMID:17109745 NCBI chr 5:59,490,689...59,509,139
Ensembl chr 5:59,491,096...59,509,138
JBrowse link
G Col11a1 collagen type XI alpha 1 chain multiple interactions
decreases expression
EXP Glucosamine inhibits the reaction [IL1B results in decreased expression of COL11A1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of COL11A1 mRNA] CTD PMID:17109745 NCBI chr 2:216,863,423...217,056,523
Ensembl chr 2:216,863,428...217,056,523
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions
decreases expression
ISO Glucosamine inhibits the reaction [IL1B protein results in increased expression of COL1A1 mRNA]
Glucosamine results in decreased expression of COL1A1 mRNA
CTD PMID:18321735 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions
affects expression
increases expression
ISO
EXP
Glucosamine analog affects the reaction [IL1B results in decreased expression of COL2A1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of COL2A1 mRNA]
Glucosamine inhibits the reaction [IL1B results in decreased expression of COL2A1 mRNA]
Glucosamine analog affects the expression of COL2A1 mRNA
Glucosamine analog results in increased expression of COL2A1 mRNA; Glucosamine results in increased expression of COL2A1 mRNA
CTD PMID:16300972, PMID:17109745, PMID:17337215, PMID:18321735 NCBI chr 7:139,454,945...139,484,403
Ensembl chr 7:139,455,242...139,483,997
JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions EXP Glucosamine inhibits the reaction [IL1B results in decreased expression of COL3A1 mRNA] CTD PMID:17109745 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Col8a1 collagen type VIII alpha 1 chain multiple interactions
decreases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of COL8A1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of COL8A1 mRNA] CTD PMID:17109745 NCBI chr11:44,877,690...45,006,203
Ensembl chr11:44,877,859...45,007,891
JBrowse link
G Csf1 colony stimulating factor 1 multiple interactions
decreases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of CSF1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CSF1 mRNA] CTD PMID:17109745 NCBI chr 2:210,522,370...210,550,546
Ensembl chr 2:210,522,375...210,550,560
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions
increases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of CSF2 mRNA]
Glucosamine results in increased expression of CSF2 mRNA
CTD PMID:17109745 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Csf3 colony stimulating factor 3 multiple interactions
increases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of CSF3 mRNA]
Glucosamine results in increased expression of CSF3 mRNA
CTD PMID:17109745 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
JBrowse link
G Ctsd cathepsin D affects localization
multiple interactions
increases activity
decreases expression
ISO Glucosamine affects the localization of CTSD protein
pepstatin inhibits the reaction [Glucosamine results in decreased expression of CTSD protein alternative form]
Glucosamine results in increased activity of CTSD protein
CTD PMID:15972124, PMID:16850161 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Cul2 cullin 2 multiple interactions ISO Glucosamine analog inhibits the reaction [TNF results in increased expression of CUL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CUL2 mRNA] CTD PMID:18173918 NCBI chr17:56,952,480...56,992,716
Ensembl chr17:56,952,480...56,992,694
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions
decreases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CXCL1 mRNA] CTD PMID:17109745 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO
EXP
Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA]
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL10 mRNA]
CTD PMID:17109745, PMID:20737476 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 multiple interactions EXP Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL11 mRNA] CTD PMID:17109745 NCBI chr14:17,195,395...17,198,170
Ensembl chr14:17,195,014...17,198,291
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 multiple interactions
decreases expression
EXP Glucosamine promotes the reaction [IL1B results in decreased expression of CXCL12 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of CXCL12 mRNA] CTD PMID:17109745 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions
increases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL2 mRNA] CTD PMID:17109745 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions
increases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL3 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL3 mRNA] CTD PMID:17109745 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 multiple interactions EXP Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL5 mRNA] CTD PMID:17109745 NCBI chr14:18,860,201...18,920,839
Ensembl chr14:18,860,264...18,862,407
JBrowse link
G Cyba cytochrome b-245 alpha chain decreases expression ISO Glucosamine results in decreased expression of CYBA mRNA CTD PMID:18077487 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Cycs cytochrome c, somatic affects localization ISO Glucosamine affects the localization of CYCS protein CTD PMID:15972124, PMID:22020377 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp51 cytochrome P450, family 51 increases expression ISO Glucosamine results in increased expression of CYP51 mRNA CTD PMID:17178593 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018
JBrowse link
G Dbi diazepam binding inhibitor, acyl-CoA binding protein increases expression ISO Glucosamine results in increased expression of DBI mRNA CTD PMID:17178593 NCBI chr13:36,147,667...36,156,076
Ensembl chr13:36,117,119...36,174,908
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
decreases expression
ISO Glucosamine results in increased expression of DDIT3 protein
Glucosamine results in increased expression of DDIT3 mRNA; Glucosamine results in increased expression of DDIT3 protein
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of DDIT3 protein]
Glucosamine results in decreased expression of DDIT3 mRNA
CTD PMID:16380481, PMID:17178593, PMID:30602124 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddit4l DNA-damage-inducible transcript 4-like increases expression EXP Glucosamine results in increased expression of DDIT4L mRNA CTD PMID:17109745 NCBI chr 2:242,882,219...242,885,088
Ensembl chr 2:242,882,306...242,885,131
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase increases expression ISO Glucosamine results in increased expression of DHCR7 mRNA CTD PMID:17178593 NCBI chr 1:217,018,916...217,034,890
Ensembl chr 1:217,018,916...217,034,904
JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 decreases expression ISO Glucosamine results in decreased expression of DNAJB11 mRNA CTD PMID:17178593 NCBI chr11:81,741,342...81,757,806
Ensembl chr11:81,741,297...81,757,813
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 decreases expression ISO Glucosamine results in decreased expression of DNAJB9 mRNA CTD PMID:17178593 NCBI chr 6:64,165,913...64,170,122
Ensembl chr 6:64,165,913...64,170,151
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 decreases expression ISO Glucosamine results in decreased expression of DNAJC3 mRNA CTD PMID:17178593 NCBI chr15:104,186,918...104,226,236
Ensembl chr15:104,186,792...104,226,329
JBrowse link
G Dspp dentin sialophosphoprotein decreases expression ISO Glucosamine analog results in decreased expression of DSPP mRNA CTD PMID:20458730 NCBI chr14:6,926,972...6,933,079
Ensembl chr14:6,926,976...6,933,070
JBrowse link
G Dusp5 dual specificity phosphatase 5 multiple interactions
increases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of DUSP5 mRNA]
Glucosamine results in increased expression of DUSP5 mRNA
CTD PMID:17109745 NCBI chr 1:274,245,184...274,258,595
Ensembl chr 1:274,245,184...274,258,595
JBrowse link
G Dusp7 dual specificity phosphatase 7 multiple interactions
decreases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of DUSP7 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of DUSP7 mRNA] CTD PMID:17109745 NCBI chr 8:115,069,095...115,076,130
Ensembl chr 8:115,069,095...115,076,130
JBrowse link
G Dync1i1 dynein cytoplasmic 1 intermediate chain 1 decreases expression EXP Glucosamine results in decreased expression of DYNC1I1 mRNA CTD PMID:17109745 NCBI chr 4:30,807,755...31,121,097
Ensembl chr 4:30,807,879...31,121,090
JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 decreases expression ISO Glucosamine results in decreased expression of EDEM1 mRNA CTD PMID:17178593 NCBI chr 4:140,886,644...140,918,654
Ensembl chr 4:140,886,545...140,915,779
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases phosphorylation
EXP
ISO
EIF2AK3 gene mutant form inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]
EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of ATF4 mRNA]; EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; EIF2AK3 protein affects the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]
Glucosamine results in increased phosphorylation of EIF2AK3 protein
CTD PMID:16324875, PMID:19383982, PMID:30602124 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation
multiple interactions
ISO
EXP
Glucosamine results in increased phosphorylation of EIF2S1 protein
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]; EIF2AK3 protein affects the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]; GSK2656157 inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]
EIF2AK3 gene mutant form inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]
CTD PMID:16324875, PMID:19383982, PMID:30602124 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 increases expression ISO Glucosamine results in increased expression of ELOVL6 mRNA CTD PMID:17178593 NCBI chr 2:234,187,490...234,296,124
Ensembl chr 2:234,189,105...234,296,145
Ensembl chr 2:234,189,105...234,296,145
JBrowse link
G Epas1 endothelial PAS domain protein 1 decreases expression
multiple interactions
EXP Glucosamine results in decreased expression of EPAS1 mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of EPAS1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of EPAS1 mRNA]
CTD PMID:17109745 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Eprs glutamyl-prolyl-tRNA synthetase decreases expression ISO Glucosamine results in decreased expression of EPRS mRNA CTD PMID:17178593 NCBI chr13:103,300,911...103,371,651
Ensembl chr13:103,300,932...103,371,577
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO ERN1 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; ERN1 protein affects the reaction [Glucosamine results in increased splicing of XBP1 mRNA] CTD PMID:30602124 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914
JBrowse link
G Fabp4 fatty acid binding protein 4 increases expression ISO
EXP
Glucosamine results in increased expression of FABP4 mRNA CTD PMID:15694357 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fasn fatty acid synthase increases expression ISO Glucosamine results in increased expression of FASN mRNA CTD PMID:22096489 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fbp2 fructose-bisphosphatase 2 increases expression ISO Glucosamine results in increased expression of FBP2 mRNA CTD PMID:17178593 NCBI chr17:372,554...389,918
Ensembl chr17:372,551...389,967
JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions EXP Glucosamine promotes the reaction [Glucose results in increased expression of FGF2 mRNA] CTD PMID:1518840 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fgf7 fibroblast growth factor 7 decreases expression
multiple interactions
EXP Glucosamine results in decreased expression of FGF7 mRNA
IL1B inhibits the reaction [Glucosamine results in decreased expression of FGF7 mRNA]
CTD PMID:17109745 NCBI chr 3:118,315,859...118,368,464
Ensembl chr 3:118,317,761...118,366,872
JBrowse link
G Fgf9 fibroblast growth factor 9 multiple interactions
increases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of FGF9 mRNA]
Glucosamine results in increased expression of FGF9 mRNA
CTD PMID:17109745 NCBI chr15:38,341,657...38,386,945
Ensembl chr15:38,341,089...38,387,316
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 multiple interactions
increases expression
EXP Glucosamine inhibits the reaction [IL1B results in decreased expression of FGFR1 mRNA]
Glucosamine results in increased expression of FGFR1 mRNA
CTD PMID:17109745 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
JBrowse link
G Fkbp11 FKBP prolyl isomerase 11 decreases expression ISO Glucosamine results in decreased expression of FKBP11 mRNA CTD PMID:17178593 NCBI chr 7:140,398,253...140,402,664
Ensembl chr 7:140,398,199...140,437,467
JBrowse link
G Fn1 fibronectin 1 decreases expression ISO
EXP
Glucosamine results in decreased expression of FN1 protein CTD PMID:17178593 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Glucosamine analog inhibits the reaction [Buthionine Sulfoximine results in increased expression of FOS mRNA]
Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein]
CTD PMID:19375915, PMID:21825963 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) decreases cleavage
multiple interactions
ISO Glucosamine results in decreased cleavage of FURIN protein alternative form
Glucosamine results in decreased glycosylation of and results in decreased activity of FURIN protein
CTD PMID:19909832 NCBI chr 1:142,185,092...142,198,167
Ensembl chr 1:142,185,094...142,197,182
JBrowse link
G Fxyd2 FXYD domain-containing ion transport regulator 2 increases expression EXP Glucosamine results in increased expression of FXYD2 mRNA CTD PMID:17109745 NCBI chr 8:49,710,334...49,717,492
Ensembl chr 8:49,710,477...49,716,955
JBrowse link
G Gatm glycine amidinotransferase decreases expression EXP Glucosamine results in decreased expression of GATM mRNA CTD PMID:17109745 NCBI chr 3:114,711,570...114,728,155
Ensembl chr 3:114,711,562...114,728,410
JBrowse link
G Gck glucokinase decreases expression EXP Glucosamine results in decreased expression of GCK mRNA CTD PMID:11893929 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO Glucosamine analog results in increased expression of GCLC mRNA CTD PMID:21825963 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gfpt1 glutamine fructose-6-phosphate transaminase 1 multiple interactions EXP [Glucosamine co-treated with INS1 protein] affects the localization of GFPT1 protein CTD PMID:9453242 NCBI chr 4:118,852,046...118,901,583
Ensembl chr 4:118,852,062...118,901,591
JBrowse link
G Glrx glutaredoxin increases expression ISO Glucosamine results in increased expression of GLRX mRNA CTD PMID:17178593 NCBI chr 2:2,606,032...2,615,944
Ensembl chr 2:2,605,996...2,615,944
JBrowse link
G Gnpnat1 glucosamine-phosphate N-acetyltransferase 1 decreases expression ISO Glucosamine results in decreased expression of GNPNAT1 mRNA CTD PMID:17178593 NCBI chr15:19,721,292...19,734,032
Ensembl chr15:19,721,293...19,733,967
JBrowse link
G Gnptab N-acetylglucosamine-1-phosphate transferase subunits alpha and beta increases expression ISO Glucosamine results in increased expression of GNPTAB mRNA CTD PMID:17178593 NCBI chr 7:28,956,363...29,023,232
Ensembl chr 7:28,956,512...29,022,868
JBrowse link
G Gpd1l glycerol-3-phosphate dehydrogenase 1-like increases expression ISO Glucosamine results in increased expression of GPD1L mRNA CTD PMID:17178593 NCBI chr 8:122,957,570...122,987,236
Ensembl chr 8:122,954,948...122,987,191
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist multiple interactions
decreases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of GREM1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of GREM1 mRNA] CTD PMID:17109745 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989
JBrowse link
G Gspt1 G1 to S phase transition 1 multiple interactions ISO Glucosamine analog inhibits the reaction [TNF results in increased expression of GSPT1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of GSPT1 mRNA] CTD PMID:18173918 NCBI chr10:4,313,100...4,347,661
Ensembl chr10:4,312,863...4,446,200
JBrowse link
G Gstt1 glutathione S-transferase theta 1 increases expression ISO Glucosamine results in increased expression of GSTT1 mRNA CTD PMID:17178593 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Hapln1 hyaluronan and proteoglycan link protein 1 decreases expression
multiple interactions
EXP Glucosamine results in decreased expression of HAPLN1 mRNA
Glucosamine inhibits the reaction [IL1B results in decreased expression of HAPLN1 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of HAPLN1 mRNA]
CTD PMID:17109745 NCBI chr 2:18,354,542...18,419,077
Ensembl chr 2:18,354,542...18,419,071
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 decreases expression ISO Glucosamine results in decreased expression of HERPUD1 mRNA CTD PMID:17178593 NCBI chr19:11,046,905...11,057,440
Ensembl chr19:11,046,909...11,057,254
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
decreases expression
ISO Glucosamine affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein]; Glucosamine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]
Glucosamine results in decreased expression of HIF1A mRNA; Glucosamine results in decreased expression of HIF1A protein
CTD PMID:19254699, PMID:22020377 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hk1 hexokinase 1 increases expression ISO
EXP
Glucosamine results in increased expression of HK1 mRNA CTD PMID:11893929, PMID:17178593 NCBI chr20:31,911,460...31,979,780
Ensembl chr20:31,912,262...31,956,649
JBrowse link
G Hmga1 high mobility group AT-hook 1 increases expression EXP Glucosamine results in increased expression of HMGA1 mRNA CTD PMID:17109745 NCBI chr20:7,132,501...7,140,155
Ensembl chr20:7,136,007...7,138,980
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO Glucosamine results in increased expression of HMGCS1 mRNA CTD PMID:17178593 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hmmr hyaluronan-mediated motility receptor decreases expression EXP Glucosamine results in decreased expression of HMMR mRNA CTD PMID:17109745 NCBI chr10:25,861,490...25,890,639
Ensembl chr10:25,861,490...25,890,639
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO Glucosamine inhibits the reaction [IL1B results in decreased expression of HMOX1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of HMOX1 protein]
Glucosamine results in increased expression of HMOX1 mRNA; Glucosamine results in increased expression of HMOX1 protein
CTD PMID:18077487 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hoxa1 homeobox A1 decreases expression ISO Glucosamine results in decreased expression of HOXA1 mRNA CTD PMID:17178593 NCBI chr 4:82,124,358...82,127,182
Ensembl chr 4:82,125,406...82,127,066
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase decreases expression EXP Glucosamine results in decreased expression of HPGD mRNA CTD PMID:17109745 NCBI chr16:37,457,134...37,495,758
Ensembl chr16:37,457,135...37,495,758
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 decreases expression
increases expression
ISO
EXP
Glucosamine results in decreased expression of HSP90B1 mRNA
Glucosamine results in increased expression of HSP90B1 protein
CTD PMID:15618547, PMID:17109745, PMID:17178593 NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression
decreases expression
ISO
EXP
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; tauroursodeoxycholic acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 protein]
Glucosamine results in increased expression of HSPA5 mRNA; Glucosamine results in increased expression of HSPA5 protein
Glucosamine results in decreased expression of HSPA5 mRNA
CTD PMID:15618547, PMID:16380481, PMID:17178593, PMID:19383982, PMID:20165829, PMID:22020377, PMID:30602124 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hyou1 hypoxia up-regulated 1 decreases expression ISO Glucosamine results in decreased expression of HYOU1 mRNA CTD PMID:17178593 NCBI chr 8:48,699,796...48,711,912
Ensembl chr 8:48,699,769...48,711,910
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
decreases activity
ISO
EXP
Alloxan inhibits the reaction [Glucosamine inhibits the reaction [CAP18 lipopolysaccharide-binding protein results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [[IL6 co-treated with TNF] results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [CAP18 lipopolysaccharide-binding protein results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [CAP18 lipopolysaccharide-binding protein results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IFNG promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IFNG results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [IFNG results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IL1B promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IL1B results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IL6 results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [TNF promotes the reaction [IFNG results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF promotes the reaction [IL1B results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of ICAM1 protein]
Glucosamine results in decreased activity of ICAM1 protein
Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]
CTD PMID:16431966, PMID:16822504, PMID:17238806, PMID:18949387, PMID:19020780, PMID:19098112 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein increases expression ISO Glucosamine results in increased expression of ID1 mRNA CTD PMID:17178593 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
JBrowse link
G Id2 inhibitor of DNA binding 2 increases expression ISO Glucosamine results in increased expression of ID2 mRNA CTD PMID:17178593 NCBI chr 6:44,360,077...44,361,908
Ensembl chr 6:44,348,501...44,363,915
JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein increases expression ISO Glucosamine results in increased expression of ID3 mRNA CTD PMID:17178593 NCBI chr 5:154,489,603...154,491,172
Ensembl chr 5:154,489,590...154,491,223
JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 increases expression ISO Glucosamine results in increased expression of IDH1 mRNA CTD PMID:17178593 NCBI chr 9:71,882,108...71,911,645
Ensembl chr 9:71,882,105...71,900,044
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 increases expression ISO Glucosamine results in increased expression of IFIT3 mRNA CTD PMID:17178593 NCBI chr 1:252,906,234...252,911,377
Ensembl chr 1:252,906,234...252,911,382
JBrowse link
G Ifng interferon gamma decreases secretion
multiple interactions
ISO Glucosamine results in decreased secretion of IFNG protein
Glucosamine inhibits the reaction [IFNG promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IFNG results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [IFNG results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IFNG results in increased localization of STAT1 protein modified form]; Glucosamine inhibits the reaction [IFNG results in increased phosphorylation of and results in increased localization of STAT1 protein]; Glucosamine inhibits the reaction [TNF promotes the reaction [IFNG results in increased expression of ICAM1 protein]]
CTD PMID:14507305, PMID:16431966, PMID:16822504, PMID:17238806 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 multiple interactions
decreases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of IGFBP3 mRNA]; IL1B inhibits the reaction [Glucosamine results in increased expression of IGFBP3 mRNA]
Glucosamine results in decreased expression of IGFBP3 mRNA
CTD PMID:17109745 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 decreases expression ISO Glucosamine results in decreased expression of IGFBP4 mRNA CTD PMID:17178593 NCBI chr10:86,950,555...86,962,563
Ensembl chr10:86,950,557...86,962,578
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 multiple interactions
increases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of IGFBP5 mRNA]
Glucosamine results in increased expression of IGFBP5 mRNA
CTD PMID:17109745 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of IKBKB protein] CTD PMID:18786831 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma multiple interactions
decreases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of IKBKG mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of IKBKG mRNA] CTD PMID:17109745 NCBI chr  X:156,254,187...156,280,046
Ensembl chr  X:156,257,173...156,270,748
JBrowse link
G Il11 interleukin 11 multiple interactions EXP Glucosamine inhibits the reaction [IL1B results in increased expression of IL11 mRNA] CTD PMID:17109745 NCBI chr 1:72,636,959...72,643,255
Ensembl chr 1:72,635,267...72,643,255
JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 multiple interactions
decreases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of IL13RA1 mRNA]
Glucosamine results in decreased expression of IL13RA1 mRNA
CTD PMID:17109745 NCBI chr  X:122,724,081...122,783,801
Ensembl chr  X:122,724,129...122,781,479
JBrowse link
G Il1a interleukin 1 alpha multiple interactions
increases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of IL1A mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of IL1A mRNA] CTD PMID:17109745 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
decreases expression
ISO
EXP
[Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of NOS2 protein; [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGES protein; [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGS2 protein; [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in increased expression of TIMP3 mRNA; [Glucosamine co-treated with Chondroitin Sulfates] inhibits the reaction [IL1B protein results in increased secretion of Dinoprostone]; [Glucosamine co-treated with Chondroitin Sulfates] inhibits the reaction [IL1B protein results in increased secretion of Nitrites]; Glucosamine analog affects the reaction [IL1B protein results in increased abundance of Nitric Oxide]; Glucosamine analog affects the reaction [IL1B results in decreased expression of ACAN mRNA]; Glucosamine analog affects the reaction [IL1B results in decreased expression of COL2A1 mRNA]; Glucosamine analog affects the reaction [IL1B results in increased phosphorylation of AKT1 protein]; Glucosamine analog inhibits the reaction [IL1B protein results in increased abundance of Dinoprostone]; Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP13]; Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP1]; Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP3]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP1 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP13 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP3 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of CXCL8 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP1 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP13 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased localization of RELA protein]; Glucosamine analog inhibits the reaction [IL1B results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL2 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL5 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CXCL8 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK1 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK3 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK8 protein]; Glucosamine inhibits the reaction [[OSM protein co-treated with IL1B protein] results in decreased methylation of IL1B promoter]; Glucosamine inhibits the reaction [[OSM protein co-treated with IL1B protein] results in increased expression of IL1B mRNA]; Glucosamine inhibits the reaction [IL1B promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of ACAN mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of COL2A1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased activity of JUN protein]; Glucosamine inhibits the reaction [IL1B protein results in increased activity of JUND protein]; Glucosamine inhibits the reaction [IL1B protein results in increased degradation of NFKBIA protein]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of COL1A1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased localization of NFKB1 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased localization of RELA protein]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of Dinoprostone]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP1 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP13 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP3 protein]; Glucosamine inhibits the reaction [IL1B results in decreased expression of HMOX1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of HMOX1 protein]; Glucosamine inhibits the reaction [IL1B results in increased abundance of Dinoprostone]; Glucosamine inhibits the reaction [IL1B results in increased abundance of Nitric Oxide]; Glucosamine inhibits the reaction [IL1B results in increased abundance of Nitrites]; Glucosamine inhibits the reaction [IL1B results in increased degradation of NFKB1 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL8 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL8 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of NOS2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PTGES mRNA]; Glucosamine inhibits the reaction [IL1B results in increased localization of RELA protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK1 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK14 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK3 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK8 protein]; Glucosamine inhibits the reaction [IL1B results in increased secretion of CXCL8 protein]; Glucosamine inhibits the reaction [TNF promotes the reaction [IL1B results in increased expression of ICAM1 protein]]; Glucosamine promotes the reaction [IL1B results in increased expression of PPARG]; Glucosamine promotes the reaction [IL1B results in increased phosphorylation of AKT1 protein]
Glucosamine results in increased expression of IL1B mRNA
Glucosamine results in decreased expression of IL1B mRNA
[IL1B protein co-treated with Glucosamine] results in increased expression of IL1R2 mRNA; Glucosamine affects the reaction [IL1B results in decreased expression of ADAM15 mRNA]; Glucosamine affects the reaction [IL1B results in decreased expression of OAT mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased activity of B3GAT3 protein]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of B3GAT3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased abundance of Dinoprostone]; Glucosamine inhibits the reaction [IL1B protein results in increased abundance of Nitric Oxide]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of ACAN mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of COL11A1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of COL2A1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of COL3A1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of FGFR1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of HAPLN1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of LAMA4 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of SDC2 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of SOX4 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of THBS4 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of TIMP2 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of TIMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ADAM17 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ADAMTS1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ASS1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of BGN mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of BMP2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of BMP6 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of BMP7 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL20 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL22 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL7 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of COL8A1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CSF1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CSF2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CSF3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL10 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL11 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of DUSP5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of DUSP7 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of EPAS1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of FGF9 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of GREM1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IGFBP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IGFBP5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IKBKG mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL11 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL13RA1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL1A mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL1B mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL23R mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of JAK2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of JUNB mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP10 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP12 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP13 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP9 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of NFKBIA mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of NFKBIB mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of NGF mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of NOS2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PDGFA mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G2A mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G4A mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of RELB mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of SDC4 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of SLC7A8 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of TIMP1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of TNFAIP6 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of TNK2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of VCAN mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Glucosamine promotes the reaction [IL1B results in decreased expression of BMP4 mRNA]; Glucosamine promotes the reaction [IL1B results in decreased expression of CXCL12 mRNA]; IL1B affects the reaction [Glucosamine affects the expression of PDGFA mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of ADAM15 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of BGN mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of COL11A1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of CXCL12 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of DUSP7 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of EPAS1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of IKBKG mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of JUNB mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of TNFAIP6 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of VCAN mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of ADAM17 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of IL1A mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of JAK2 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of LAMA4 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of MMP9 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of NFKBIB mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of TIMP3 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of ADAMTS1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of COL8A1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CSF1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CXCL1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of FGF7 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of GREM1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of NFKBIA mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of PLA2G2A mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of PLA2G5 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of SDC4 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of SLC7A8 mRNA]; IL1B inhibits the reaction [Glucosamine results in increased expression of IGFBP3 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of HAPLN1 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of SDC2 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of THBS4 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of AZIN1 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL20 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL7 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL3 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP10 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP12 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP13 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP3 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of NOS2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of TIMP1 mRNA]
Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL1B protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]
CTD PMID:11229466, PMID:11801247, PMID:12681956, PMID:15144122, PMID:16822504, PMID:17109745, PMID:17238806, PMID:17337215, PMID:17605605, PMID:17925024, PMID:18026701, PMID:18077487, PMID:18080321, PMID:18321735, PMID:18340449, PMID:18786831, PMID:19626664, PMID:19656660, PMID:20737476, PMID:21219853, PMID:22089456 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1r2 interleukin 1 receptor type 2 multiple interactions EXP [IL1B protein co-treated with Glucosamine] results in increased expression of IL1R2 mRNA CTD PMID:11801247 NCBI chr 9:46,840,646...46,881,241
Ensembl chr 9:46,840,992...46,881,264
JBrowse link
G Il2 interleukin 2 decreases secretion ISO Glucosamine results in decreased secretion of IL2 protein CTD PMID:14507305 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il23r interleukin 23 receptor multiple interactions EXP Glucosamine inhibits the reaction [IL1B results in increased expression of IL23R mRNA] CTD PMID:17109745 NCBI chr 4:98,203,788...98,306,729
Ensembl chr 4:98,203,958...98,305,173
JBrowse link
G Il33 interleukin 33 decreases expression EXP Glucosamine results in decreased expression of IL33 mRNA CTD PMID:17109745 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029
JBrowse link
G Il4 interleukin 4 decreases secretion
decreases expression
ISO Glucosamine results in decreased secretion of IL4 protein
Glucosamine results in decreased expression of IL4
CTD PMID:14507305, PMID:21284687 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il5 interleukin 5 decreases secretion
decreases expression
ISO Glucosamine results in decreased secretion of IL5 protein
Glucosamine results in decreased expression of IL5
CTD PMID:14507305, PMID:21284687 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
ISO
EXP
Glucosamine analog inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [[IL6 co-treated with TNF] results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IL6 results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL6 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of IL6 mRNA]
Glucosamine inhibits the reaction [IL1B results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
Glucosamine analog results in decreased expression of IL6 mRNA; Glucosamine results in decreased expression of IL6 mRNA
Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL6 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]
CTD PMID:16822504, PMID:17109745, PMID:18786831, PMID:19098112, PMID:20093129, PMID:20113495, PMID:20307528, PMID:20737476 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ins2 insulin 2 multiple interactions ISO 4-phenylbutyric acid inhibits the reaction [Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]]; Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]; tauroursodeoxycholic acid inhibits the reaction [Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]] CTD PMID:20165829 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Irf1 interferon regulatory factor 1 multiple interactions ISO Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IRF1 mRNA] CTD PMID:20737476 NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531
JBrowse link
G Isyna1 inositol-3-phosphate synthase 1 increases expression EXP Glucosamine results in increased expression of ISYNA1 mRNA CTD PMID:17109745 NCBI chr16:20,589,497...20,592,333
Ensembl chr16:20,589,481...20,592,449
JBrowse link
G Jak2 Janus kinase 2 multiple interactions
increases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of JAK2 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of JAK2 mRNA] CTD PMID:17109745 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Glucosamine inhibits the reaction [IL1B protein results in increased activity of JUN protein]
Glucosamine analog inhibits the reaction [Buthionine Sulfoximine results in increased expression of JUN mRNA]
CTD PMID:17925024, PMID:21825963 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions
decreases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of JUNB mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of JUNB mRNA] CTD PMID:17109745 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Glucosamine inhibits the reaction [IL1B protein results in increased activity of JUND protein] CTD PMID:17925024 NCBI chr16:20,485,028...20,486,707
Ensembl chr16:20,485,029...20,486,707
JBrowse link
G Kcnj16 potassium inwardly-rectifying channel, subfamily J, member 16 increases expression ISO Glucosamine results in increased expression of KCNJ16 mRNA CTD PMID:17178593 NCBI chr10:99,330,894...99,391,551
Ensembl chr10:99,388,130...99,389,898
JBrowse link
G Kif11 kinesin family member 11 decreases expression EXP Glucosamine results in decreased expression of KIF11 mRNA CTD PMID:17109745 NCBI chr 1:256,035,866...256,088,299
Ensembl chr 1:256,035,866...256,088,299
JBrowse link
G Kif4a kinesin family member 4A decreases expression EXP Glucosamine results in decreased expression of KIF4A mRNA CTD PMID:17109745 NCBI chr  X:70,461,700...70,561,084
Ensembl chr  X:70,461,718...70,561,189
JBrowse link
G Klf10 Kruppel-like factor 10 increases expression ISO Glucosamine results in increased expression of KLF10 mRNA CTD PMID:17178593 NCBI chr 7:77,156,010...77,162,096
Ensembl chr 7:77,156,006...77,162,148
JBrowse link
G Lama4 laminin subunit alpha 4 multiple interactions
increases expression
EXP Glucosamine inhibits the reaction [IL1B results in decreased expression of LAMA4 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of LAMA4 mRNA] CTD PMID:17109745 NCBI chr20:44,060,715...44,201,966
Ensembl chr20:44,060,731...44,209,614
JBrowse link
G Lamb1 laminin subunit beta 1 multiple interactions ISO TXNIP promotes the reaction [Glucosamine results in increased expression of LAMB1 mRNA] CTD PMID:17178593 NCBI chr 6:50,528,796...50,596,593
Ensembl chr 6:50,528,823...50,596,079
JBrowse link
G Lamc1 laminin subunit gamma 1 multiple interactions ISO TXNIP promotes the reaction [Glucosamine results in increased expression of LAMC1 mRNA] CTD PMID:17178593 NCBI chr13:70,656,727...70,783,515
Ensembl chr13:70,658,707...70,783,515
JBrowse link
G Lcn2 lipocalin 2 decreases expression ISO Glucosamine results in decreased expression of LCN2 mRNA CTD PMID:17178593 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Lpin1 lipin 1 increases expression ISO Glucosamine results in increased expression of LPIN1 mRNA CTD PMID:17178593 NCBI chr 6:41,796,214...41,905,149
Ensembl chr 6:41,799,749...41,870,046
JBrowse link
G Mafb MAF bZIP transcription factor B increases expression EXP Glucosamine results in increased expression of MAFB mRNA CTD PMID:17109745 NCBI chr 3:156,338,993...156,340,913
Ensembl chr 3:156,339,004...156,340,913
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAPK1 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK1 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK1 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]
Glucosamine analog results in increased phosphorylation of MAPK1 protein
CTD PMID:18080321, PMID:18340449, PMID:19375915, PMID:19626664, PMID:20307528 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK14 protein] CTD PMID:19626664 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAPK3 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK3 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK3 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]
Glucosamine analog results in increased phosphorylation of MAPK3 protein
CTD PMID:18080321, PMID:18340449, PMID:19375915, PMID:19626664, PMID:20307528 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation
ISO Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK8 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK8 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]
Glucosamine analog results in increased phosphorylation of MAPK8 protein
CTD PMID:18080321, PMID:19626664, PMID:20307528 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression ISO Glucosamine results in decreased expression of MCL1 mRNA; Glucosamine results in decreased expression of MCL1 protein CTD PMID:22020377 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Mef2a myocyte enhancer factor 2a multiple interactions
decreases expression
ISO
EXP
4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; tauroursodeoxycholic acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; tauroursodeoxycholic acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]
Glucosamine results in decreased expression of MEF2A mRNA; Glucosamine results in decreased expression of MEF2A protein
CTD PMID:20165829 NCBI chr 1:128,207,715...128,341,681
Ensembl chr 1:128,209,971...128,341,263
JBrowse link
G Mettl1 methyltransferase like 1 decreases expression ISO Glucosamine results in decreased expression of METTL1 mRNA CTD PMID:17178593 NCBI chr 7:70,328,470...70,333,045
Ensembl chr 7:70,328,391...70,333,166
JBrowse link
G Mfap3l microfibril associated protein 3 like increases expression ISO Glucosamine results in increased expression of MFAP3L mRNA CTD PMID:17178593 NCBI chr16:32,734,059...32,777,091
Ensembl chr16:32,738,265...32,753,278
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression EXP Glucosamine results in decreased expression of MKI67 mRNA CTD PMID:17109745 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions ISO Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP1]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP1 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP1 protein] CTD PMID:15144122, PMID:17925024, PMID:18080321 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp10 matrix metallopeptidase 10 increases expression
multiple interactions
EXP Glucosamine results in increased expression of MMP10 mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of MMP10 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP10 mRNA]
CTD PMID:17109745 NCBI chr 8:5,734,348...5,742,243
Ensembl chr 8:5,734,348...5,742,243
JBrowse link
G Mmp12 matrix metallopeptidase 12 multiple interactions
increases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of MMP12 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP12 mRNA] CTD PMID:17109745 NCBI chr 8:5,594,717...5,616,494
Ensembl chr 8:5,606,592...5,616,493
JBrowse link
G Mmp13 matrix metallopeptidase 13 affects expression
multiple interactions
increases expression
ISO
EXP
Glucosamine analog affects the expression of MMP13 mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of MMP13 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP13 mRNA]
Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP13]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP13 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP13 mRNA]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP13 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP13 protein]
CTD PMID:15144122, PMID:17109745, PMID:17337215, PMID:17925024, PMID:18080321, PMID:19656660 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression
ISO
EXP
Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP2 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein]
IL1B promotes the reaction [Glucosamine results in increased expression of MMP2 mRNA]
CTD PMID:17109745, PMID:17498959, PMID:19375915 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions
increases expression
decreases expression
ISO
EXP
[Glucosamine co-treated with Chondroitin Sulfates] results in decreased expression of MMP3 mRNA; [Glucosamine co-treated with Chondroitin Sulfates] results in decreased secretion of MMP3 protein; Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP3]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP3 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP3 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 protein]; Glucosamine results in decreased expression of and results in decreased activity of MMP3 protein
Glucosamine results in increased expression of MMP3 mRNA
Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP3 mRNA]
Glucosamine analog results in decreased expression of MMP3 mRNA
CTD PMID:11229466, PMID:12801482, PMID:15144122, PMID:16300972, PMID:17109745, PMID:17925024, PMID:18080321, PMID:18340449, PMID:20110869 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression
ISO
EXP
Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]
Glucosamine results in increased expression of MMP9 mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of MMP9 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of MMP9 mRNA]
CTD PMID:17109745, PMID:17498959, PMID:19375915 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mnda myeloid cell nuclear differentiation antigen increases expression ISO Glucosamine results in increased expression of IFI204 mRNA CTD PMID:17178593 NCBI chr13:92,073,664...92,091,335
Ensembl chr13:92,073,668...92,089,980
JBrowse link
G Mpo myeloperoxidase decreases activity EXP Glucosamine results in decreased activity of MPO protein CTD PMID:19098112 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mvd mevalonate diphosphate decarboxylase increases expression ISO Glucosamine results in increased expression of MVD mRNA CTD PMID:17178593 NCBI chr19:55,258,910...55,268,933
Ensembl chr19:55,258,905...55,268,951
JBrowse link
G Ndufa4 NDUFA4, mitochondrial complex associated increases expression EXP Glucosamine results in increased expression of NDUFA4 mRNA CTD PMID:17109745 NCBI chr 4:38,233,680...38,240,848
Ensembl chr 4:38,233,680...38,240,848
JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase decreases expression EXP Glucosamine results in decreased expression of NEDD4 mRNA CTD PMID:17109745 NCBI chr 8:79,323,408...79,408,842
Ensembl chr 8:79,323,408...79,408,833
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
decreases activity
ISO
EXP
Glucosamine inhibits the reaction [Hydrogen Peroxide results in increased expression of and results in increased localization of NFKB1 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased localization of NFKB1 protein]; Glucosamine inhibits the reaction [IL1B results in increased degradation of NFKB1 protein]; Glucosamine inhibits the reaction [NFKB1 results in increased degradation of RELA protein]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NFKB1 protein]
Glucosamine results in decreased activity of NFKB1 protein
Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of NFKB1 protein]
CTD PMID:12681956, PMID:16431966, PMID:16822504, PMID:17498959, PMID:18036590, PMID:18205790, PMID:20737476 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
decreases phosphorylation
decreases expression
ISO
EXP
Glucosamine analog inhibits the reaction [IL1B results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Glucosamine inhibits the reaction [IL1B protein results in increased degradation of NFKBIA protein]
Glucosamine results in decreased phosphorylation of NFKBIA protein
Glucosamine results in decreased expression of NFKBIA mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of NFKBIA mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]; IL1B inhibits the reaction [Glucosamine results in decreased expression of NFKBIA mRNA]
Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of NFKBIA protein modified form]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]
CTD PMID:12681956, PMID:17109745, PMID:18080321, PMID:18205790, PMID:19098112 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nfkbib NFKB inhibitor beta multiple interactions
increases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of NFKBIB mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of NFKBIB mRNA] CTD PMID:17109745 NCBI chr 1:86,941,073...86,948,845
Ensembl chr 1:86,941,074...86,948,845
JBrowse link
G Ngef neuronal guanine nucleotide exchange factor increases expression ISO Glucosamine results in increased expression of NGEF mRNA CTD PMID:17178593 NCBI chr 9:94,569,286...94,601,852
Ensembl chr 9:94,569,286...94,601,852
JBrowse link
G Ngf nerve growth factor multiple interactions EXP Glucosamine inhibits the reaction [IL1B results in increased expression of NGF mRNA] CTD PMID:17109745 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression
decreases expression
ISO
EXP
[Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of NOS2 protein; Glucosamine inhibits the reaction [IL1B results in increased expression of NOS2 mRNA]
Glucosamine results in increased expression of NOS2 mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of NOS2 mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of NOS2 mRNA]
Glucosamine results in decreased expression of NOS2 mRNA
Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides promotes the reaction [RELA protein binds to NOS2 promoter]]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
CTD PMID:17109745, PMID:17440993, PMID:17605605, PMID:18077487, PMID:18205790, PMID:19098112, PMID:20737476 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 affects expression EXP Glucosamine affects the expression of NR1H4 CTD PMID:19373748 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Nsdhl NAD(P) dependent steroid dehydrogenase-like increases expression ISO Glucosamine results in increased expression of NSDHL mRNA CTD PMID:17178593 NCBI chr  X:152,933,118...152,964,399
Ensembl chr  X:152,933,069...152,964,390
JBrowse link
G Nucb2 nucleobindin 2 decreases expression ISO Glucosamine results in decreased expression of NUCB2 mRNA CTD PMID:17178593 NCBI chr 1:185,106,773...185,143,278
Ensembl chr 1:185,104,656...185,143,272
JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex decreases expression EXP Glucosamine results in decreased expression of NUF2 mRNA CTD PMID:17109745 NCBI chr13:87,818,456...87,847,223
Ensembl chr13:87,818,391...87,847,263
JBrowse link
G Oat ornithine aminotransferase multiple interactions EXP Glucosamine affects the reaction [IL1B results in decreased expression of OAT mRNA] CTD PMID:17109745 NCBI chr 1:204,562,289...204,582,070
Ensembl chr 1:204,562,289...204,582,070
JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase decreases expression ISO Glucosamine results in decreased expression of OGT mRNA CTD PMID:17178593 NCBI chr  X:71,540,870...71,585,906
Ensembl chr  X:71,528,988...71,585,908
JBrowse link
G Orc2 origin recognition complex, subunit 2 decreases expression ISO Glucosamine results in decreased expression of ORC2 mRNA CTD PMID:17178593 NCBI chr 9:65,350,630...65,387,293
Ensembl chr 9:65,350,627...65,387,169
JBrowse link
G Osm oncostatin M multiple interactions ISO Glucosamine inhibits the reaction [[OSM protein co-treated with IL1B protein] results in decreased methylation of IL1B promoter]; Glucosamine inhibits the reaction [[OSM protein co-treated with IL1B protein] results in increased expression of IL1B mRNA] CTD PMID:21219853 NCBI chr14:84,457,487...84,469,426
Ensembl chr14:84,465,515...84,470,409
JBrowse link
G Ostn osteocrin increases expression
multiple interactions
ISO Glucosamine results in increased expression of OSTN mRNA
4-methylumbelliferone 8-carbaldehyde inhibits the reaction [Glucosamine results in increased expression of OSTN mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of OSTN mRNA]; [INS1 protein co-treated with Glucosamine] results in increased expression of OSTN mRNA; ATF6 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; ERN1 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; GSK2656157 inhibits the reaction [Glucosamine results in increased expression of OSTN mRNA]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]
CTD PMID:30602124 NCBI chr11:76,851,923...76,888,140
Ensembl chr11:76,851,322...76,888,178
JBrowse link
G Oxr1 oxidation resistance 1 decreases expression ISO Glucosamine results in decreased expression of OXR1 mRNA CTD PMID:17178593 NCBI chr 7:80,351,774...80,788,094
Ensembl chr 7:80,351,774...80,788,094
JBrowse link
G Pank1 pantothenate kinase 1 increases expression ISO Glucosamine results in increased expression of PANK1 mRNA CTD PMID:17178593 NCBI chr 1:253,115,400...253,189,643
Ensembl chr 1:253,119,112...253,185,533
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO Glucosamine results in increased cleavage of PARP1 protein
pepstatin inhibits the reaction [Glucosamine results in increased cleavage of PARP1 protein]
CTD PMID:16850161 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pdgfa platelet derived growth factor subunit A affects expression
multiple interactions
EXP Glucosamine affects the expression of PDGFA mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of PDGFA mRNA]; IL1B affects the reaction [Glucosamine affects the expression of PDGFA mRNA]
CTD PMID:17109745 NCBI chr12:17,734,141...17,756,186
Ensembl chr12:17,734,133...17,755,285
JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 decreases expression ISO Glucosamine results in decreased expression of PDIA4 mRNA CTD PMID:17178593 NCBI chr 4:77,470,636...77,489,535
Ensembl chr 4:77,470,636...77,489,535
JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 decreases expression ISO Glucosamine results in decreased expression of PDIA6 mRNA CTD PMID:17178593 NCBI chr 6:42,568,269...42,585,654
Ensembl chr 6:42,568,220...42,585,652
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression ISO Glucosamine results in increased expression of PDK4 mRNA CTD PMID:17178593 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link
G Pfkp phosphofructokinase, platelet increases expression ISO Glucosamine results in increased expression of PFKP mRNA CTD PMID:17178593 NCBI chr17:68,510,765...68,574,387
Ensembl chr17:68,511,064...68,559,471
JBrowse link
G Piga phosphatidylinositol glycan anchor biosynthesis, class A decreases expression ISO Glucosamine results in decreased expression of PIGA mRNA CTD PMID:17178593 NCBI chr  X:31,786,823...31,799,751
Ensembl chr  X:31,786,194...31,799,560
JBrowse link
G Pla2g2a phospholipase A2 group IIA multiple interactions
decreases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G2A mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of PLA2G2A mRNA] CTD PMID:17109745 NCBI chr 5:157,282,650...157,285,295
Ensembl chr 5:157,282,669...157,285,328
JBrowse link
G Pla2g4a phospholipase A2 group IVA affects expression
multiple interactions
EXP Glucosamine affects the expression of PLA2G4A mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G4A mRNA]
CTD PMID:17109745 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
G Pla2g5 phospholipase A2, group V multiple interactions
decreases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G5 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of PLA2G5 mRNA] CTD PMID:17109745 NCBI chr 5:157,247,601...157,268,968
Ensembl chr 5:157,247,781...157,268,903
JBrowse link
G Plat plasminogen activator, tissue type increases expression ISO Glucosamine results in increased expression of PLAT mRNA CTD PMID:17178593 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Plk1 polo-like kinase 1 increases expression
decreases expression
ISO
EXP
Glucosamine results in increased expression of PLK1 mRNA
Glucosamine results in decreased expression of PLK1 mRNA
CTD PMID:17109745, PMID:17178593 NCBI chr 1:192,115,990...192,125,969
Ensembl chr 1:192,115,966...192,125,989
JBrowse link
G Plpp3 phospholipid phosphatase 3 decreases expression EXP Glucosamine results in decreased expression of PLPP3 mRNA CTD PMID:17109745 NCBI chr 5:124,690,214...124,765,499
Ensembl chr 5:124,690,214...124,765,498
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
increases expression
ISO
EXP
Glucosamine promotes the reaction [IL1B results in increased expression of PPARG]
Glucosamine results in increased expression of PPARG mRNA
CTD PMID:15694357, PMID:22089456 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions
decreases expression
ISO
EXP
4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; tauroursodeoxycholic acid inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; tauroursodeoxycholic acid inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]
Glucosamine results in decreased expression of PPARGC1A mRNA; Glucosamine results in decreased expression of PPARGC1A protein
CTD PMID:20165829 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A decreases expression ISO Glucosamine results in decreased expression of PPM1A mRNA CTD PMID:17178593 NCBI chr 6:94,433,658...94,484,979
Ensembl chr 6:94,429,068...94,484,351
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A decreases expression ISO Glucosamine results in decreased expression of PPP1R15A mRNA CTD PMID:17178593 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Prc1 protein regulator of cytokinesis 1 decreases expression EXP Glucosamine results in decreased expression of PRC1 mRNA CTD PMID:17109745 NCBI chr 1:142,087,181...142,108,746
Ensembl chr 1:142,087,208...142,108,746
JBrowse link
G Psme3 proteasome activator subunit 3 decreases expression ISO Glucosamine results in decreased expression of PSME3 CTD PMID:21697645 NCBI chr10:89,236,256...89,244,041
Ensembl chr10:89,236,256...89,244,041
JBrowse link
G Ptges prostaglandin E synthase multiple interactions ISO [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGES protein; Glucosamine inhibits the reaction [IL1B results in increased expression of PTGES mRNA] CTD PMID:17605605, PMID:22089456 NCBI chr 3:9,727,408...9,738,752
Ensembl chr 3:9,727,408...9,738,752
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
decreases expression
multiple interactions
decreases glycosylation
ISO
EXP
Glucosamine analog results in increased expression of PTGS2 protein alternative form
Glucosamine results in decreased expression of PTGS2 mRNA
Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]
Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; Glucosamine inhibits the reaction [[Lipopolysaccharides results in increased expression of PTGS2 protein] which results in increased secretion of Dinoprostone]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
Glucosamine results in decreased glycosylation of PTGS2 protein
[Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGS2 protein; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]
CTD PMID:12681956, PMID:17440993, PMID:17605605, PMID:18205790, PMID:19656660, PMID:20737476, PMID:22089456 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin decreases expression EXP Glucosamine results in decreased expression of PTTG1 mRNA CTD PMID:17109745 NCBI chr10:29,014,332...29,026,088
Ensembl chr10:29,020,049...29,026,002
JBrowse link
G Rab32 RAB32, member RAS oncogene family increases expression ISO Glucosamine results in increased expression of RAB32 mRNA CTD PMID:17178593 NCBI chr 1:4,638,663...4,653,220
Ensembl chr 1:4,637,491...4,653,210
JBrowse link
G Racgap1 Rac GTPase-activating protein 1 decreases expression EXP Glucosamine results in decreased expression of RACGAP1 mRNA CTD PMID:17109745 NCBI chr 7:141,277,303...141,308,849
Ensembl chr 7:141,277,312...141,307,233
JBrowse link
G Rbm39 RNA binding motif protein 39 decreases expression ISO Glucosamine results in decreased expression of RBM39 mRNA CTD PMID:17178593 NCBI chr 3:151,691,498...151,724,723
Ensembl chr 3:151,691,514...151,724,654
JBrowse link
G Recql4 RecQ like helicase 4 increases expression ISO Glucosamine results in increased expression of RECQL4 mRNA CTD PMID:17178593 NCBI chr 7:117,765,892...117,773,128
Ensembl chr 7:117,763,783...117,773,134
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
decreases activity
increases localization
ISO
EXP
Alloxan inhibits the reaction [Glucosamine inhibits the reaction [TNF results in increased phosphorylation of RELA protein]]; Glucosamine analog inhibits the reaction [IL1B results in increased localization of RELA protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; Glucosamine inhibits the reaction [Hydrogen Peroxide results in increased expression of and results in increased localization of RELA protein]; Glucosamine inhibits the reaction [IL1B protein results in increased localization of RELA protein]; Glucosamine inhibits the reaction [IL1B results in increased localization of RELA protein]; Glucosamine inhibits the reaction [NFKB1 results in increased degradation of RELA protein]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; Glucosamine inhibits the reaction [TNF results in increased localization of RELA protein]; Glucosamine inhibits the reaction [TNF results in increased phosphorylation of RELA protein]
Glucosamine results in decreased activity of RELA protein
Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of RELA protein]; Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein]; Glucosamine inhibits the reaction [Lipopolysaccharides promotes the reaction [RELA protein binds to NOS2 promoter]]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of RELA mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein]
Glucosamine results in increased localization of RELA protein
CTD PMID:12681956, PMID:16431966, PMID:16822504, PMID:17238806, PMID:17498959, PMID:18036590, PMID:18080321, PMID:18205790, PMID:18340449, PMID:18786831, PMID:19020780, PMID:19375915, PMID:20307528, PMID:20737476 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit multiple interactions EXP Glucosamine inhibits the reaction [IL1B results in increased expression of RELB mRNA] CTD PMID:17109745 NCBI chr 1:80,517,081...80,545,019
Ensembl chr 1:80,517,411...80,544,825
JBrowse link
G Rhob ras homolog family member B increases expression ISO Glucosamine results in increased expression of RHOB mRNA CTD PMID:17178593 NCBI chr 6:33,689,127...33,691,301
Ensembl chr 6:33,689,127...33,691,301
JBrowse link
G Rhoc ras homolog family member C decreases expression ISO Glucosamine analog results in decreased expression of RHOC mRNA CTD PMID:16142878 NCBI chr 2:207,271,692...207,278,010
Ensembl chr 2:207,271,853...207,279,314
JBrowse link
G Rnd1 Rho family GTPase 1 multiple interactions
decreases expression
ISO Glucosamine analog inhibits the reaction [TNF results in increased expression of RND1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of RND1 mRNA]
Glucosamine results in decreased expression of RND1 mRNA
CTD PMID:17178593, PMID:18173918 NCBI chr 7:140,349,138...140,356,209
Ensembl chr 7:140,349,138...140,356,209
JBrowse link
G Rps6 ribosomal protein S6 decreases phosphorylation ISO Glucosamine results in decreased phosphorylation of RPS6 protein CTD PMID:19254699 NCBI chr 5:105,197,821...105,200,681
Ensembl chr 5:105,197,857...105,200,148
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 decreases phosphorylation ISO Glucosamine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:19254699 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
JBrowse link
G Runx2 RUNX family transcription factor 2 increases phosphorylation
increases expression
multiple interactions
ISO Glucosamine analog results in increased phosphorylation of RUNX2 protein
Glucosamine analog results in increased expression of RUNX2 mRNA
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased phosphorylation of RUNX2 protein]
CTD PMID:20458730 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
JBrowse link
G Scd2 stearoyl-Coenzyme A desaturase 2 increases expression ISO Glucosamine results in increased expression of SCD2 mRNA CTD PMID:17178593 NCBI chr 1:264,059,374...264,072,433
Ensembl chr 1:264,059,374...264,072,433
JBrowse link
G Sdc2 syndecan 2 multiple interactions
decreases expression
EXP Glucosamine inhibits the reaction [IL1B results in decreased expression of SDC2 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of SDC2 mRNA] CTD PMID:17109745 NCBI chr 7:71,572,731...71,686,139
Ensembl chr 7:71,572,941...71,686,044
JBrowse link
G Sdc4 syndecan 4 multiple interactions
decreases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of SDC4 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of SDC4 mRNA] CTD PMID:17109745 NCBI chr 3:160,872,503...160,891,190
Ensembl chr 3:160,872,503...160,891,190
JBrowse link
G Selenbp1 selenium binding protein 1 decreases expression EXP Glucosamine results in decreased expression of SELENBP1 mRNA CTD PMID:17109745 NCBI chr 2:196,105,592...196,146,474
Ensembl chr 2:196,105,569...196,113,149
JBrowse link
G Serpinb2 serpin family B member 2 increases expression EXP Glucosamine results in increased expression of SERPINB2 mRNA CTD PMID:17109745 NCBI chr13:27,449,907...27,463,015
Ensembl chr13:27,449,934...27,463,010
JBrowse link
G Serpinh1 serpin family H member 1 increases expression ISO Glucosamine results in increased expression of SERPINH1 protein CTD PMID:16380481 NCBI chr 1:164,301,010...164,308,306
Ensembl chr 1:164,301,010...164,308,317
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 decreases expression EXP Glucosamine results in decreased expression of SFRP2 mRNA CTD PMID:17109745 NCBI chr 2:182,723,732...182,731,277
Ensembl chr 2:182,723,854...182,731,764
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 decreases expression ISO Glucosamine results in decreased expression of SGK1 mRNA CTD PMID:17178593 NCBI chr 1:24,185,451...24,302,309
Ensembl chr 1:24,185,435...24,302,298
JBrowse link
G Shcbp1 SHC binding and spindle associated 1 decreases expression EXP Glucosamine results in decreased expression of SHCBP1 mRNA CTD PMID:17109745 NCBI chr16:90,613,826...90,642,683
Ensembl chr16:90,613,870...90,641,420
JBrowse link
G Slc17a1 solute carrier family 17 member 1 increases expression ISO Glucosamine results in increased expression of SLC17A1 mRNA CTD PMID:17178593 NCBI chr17:43,473,048...43,504,645 JBrowse link
G Slc23a2 solute carrier family 23 member 2 increases expression EXP Glucosamine results in increased expression of SLC23A2 mRNA CTD PMID:17109745 NCBI chr 3:124,632,491...124,842,225
Ensembl chr 3:124,632,492...124,724,252
JBrowse link
G Slc2a2 solute carrier family 2 member 2 decreases expression EXP Glucosamine results in decreased expression of SLC2A2 mRNA CTD PMID:11893929 NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions
decreases expression
increases uptake
ISO
EXP
4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; tauroursodeoxycholic acid inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; tauroursodeoxycholic acid inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]
Glucosamine results in decreased expression of SLC2A4 mRNA; Glucosamine results in decreased expression of SLC2A4 protein
SLC2A4 protein results in increased uptake of Glucosamine
Glucosamine inhibits the reaction [SLC2A4 protein results in increased uptake of Glucose]; Glucose inhibits the reaction [SLC2A4 protein results in increased uptake of Glucosamine]
CTD PMID:19373748, PMID:20165829 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link
G Slc2a6 solute carrier family 2 member 6 decreases expression ISO Glucosamine results in decreased expression of SLC2A6 mRNA CTD PMID:17178593 NCBI chr 3:5,567,729...5,575,144
Ensembl chr 3:5,568,321...5,575,136
JBrowse link
G Slc37a4 solute carrier family 37 member 4 increases expression ISO Glucosamine results in increased expression of SLC37A4 mRNA CTD PMID:17178593 NCBI chr 8:48,716,914...48,723,024
Ensembl chr 8:48,716,939...48,723,024
JBrowse link
G Slc4a4 solute carrier family 4 member 4 decreases expression EXP Glucosamine results in decreased expression of SLC4A4 mRNA CTD PMID:17109745 NCBI chr14:20,476,258...20,817,042
Ensembl chr14:20,479,323...20,920,286
JBrowse link
G Slc7a8 solute carrier family 7 member 8 increases expression
multiple interactions
EXP Glucosamine results in increased expression of SLC7A8 mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of SLC7A8 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of SLC7A8 mRNA]
CTD PMID:17109745 NCBI chr15:33,369,245...33,428,942
Ensembl chr15:33,369,216...33,428,973
JBrowse link
G Smad2 SMAD family member 2 multiple interactions
increases phosphorylation
ISO 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased phosphorylation of SMAD2 protein] CTD PMID:20458730 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 decreases expression EXP Glucosamine results in decreased expression of SMPD3 mRNA CTD PMID:17109745 NCBI chr19:38,237,963...38,321,572
Ensembl chr19:38,237,965...38,321,528
JBrowse link
G Sox4 SRY-box transcription factor 4 multiple interactions
decreases expression
EXP Glucosamine inhibits the reaction [IL1B results in decreased expression of SOX4 mRNA]
Glucosamine results in decreased expression of SOX4 mRNA
CTD PMID:17109745 NCBI chr17:37,615,022...37,619,728 JBrowse link
G Srsf3 serine and arginine rich splicing factor 3 decreases expression ISO Glucosamine results in decreased expression of SRSF3 mRNA CTD PMID:17178593 NCBI chr20:6,288,285...6,298,218
Ensembl chr20:6,288,267...6,298,213
JBrowse link
G St6gal1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 increases expression ISO Glucosamine results in increased expression of ST6GAL1 mRNA CTD PMID:17178593 NCBI chr11:80,927,601...80,981,424
Ensembl chr11:80,927,601...80,981,422
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO Glucosamine inhibits the reaction [IFNG results in increased localization of STAT1 protein modified form]; Glucosamine inhibits the reaction [IFNG results in increased phosphorylation of and results in increased localization of STAT1 protein] CTD PMID:16431966, PMID:17238806 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Tacc3 transforming, acidic coiled-coil containing protein 3 decreases expression EXP Glucosamine results in decreased expression of TACC3 mRNA CTD PMID:17109745 NCBI chr14:82,336,283...82,350,069
Ensembl chr14:82,336,324...82,347,679
JBrowse link
G Testin testin gene decreases expression EXP Glucosamine results in decreased expression of TESTIN mRNA CTD PMID:17109745 NCBI chr17:4,194,796...4,225,376
Ensembl chr17:4,212,890...4,225,376
JBrowse link
G Tgfa transforming growth factor alpha multiple interactions EXP [Glucose co-treated with Glucosamine] results in increased expression of TGFA protein; Glucosamine promotes the reaction [Glucose results in increased expression of TGFA mRNA] CTD PMID:1518840 NCBI chr 4:117,961,877...118,045,923
Ensembl chr 4:117,962,319...118,046,344
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression EXP Glucosamine analog results in increased expression of TGFB1 mRNA CTD PMID:21466783 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 increases expression
multiple interactions
ISO Glucosamine analog results in increased expression of TGFBR1 protein
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased expression of TGFBR1 protein]
CTD PMID:20458730 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
JBrowse link
G Thbs4 thrombospondin 4 multiple interactions
decreases expression
EXP Glucosamine inhibits the reaction [IL1B results in decreased expression of THBS4 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of THBS4 mRNA] CTD PMID:17109745 NCBI chr 2:22,343,727...22,385,855
Ensembl chr 2:22,343,727...22,385,855
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions
increases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of TIMP1 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of TIMP1 mRNA] CTD PMID:17109745 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 affects expression
multiple interactions
EXP Glucosamine affects the expression of TIMP2 mRNA
Glucosamine inhibits the reaction [IL1B results in decreased expression of TIMP2 mRNA]
CTD PMID:17109745 NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072
JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 multiple interactions
increases expression
ISO
EXP
[Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in increased expression of TIMP3 mRNA
Glucosamine results in increased expression of TIMP3 mRNA
Glucosamine inhibits the reaction [IL1B results in decreased expression of TIMP3 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of TIMP3 mRNA]
CTD PMID:17109745, PMID:17605605 NCBI chr 7:23,543,125...23,594,170
Ensembl chr 7:23,544,215...23,594,133
JBrowse link
G Tinag tubulointerstitial nephritis antigen increases expression ISO Glucosamine results in increased expression of TINAG mRNA CTD PMID:17178593 NCBI chr 8:84,122,113...84,320,714
Ensembl chr 8:84,279,229...84,320,746
JBrowse link
G Tk1 thymidine kinase 1 decreases expression EXP Glucosamine results in decreased expression of TK1 mRNA CTD PMID:17109745 NCBI chr10:106,817,556...106,828,888
Ensembl chr10:106,817,601...106,828,884
JBrowse link
G Tlr1 toll-like receptor 1 increases expression ISO Glucosamine results in increased expression of TLR1 mRNA CTD PMID:17178593 NCBI chr14:45,062,662...45,065,014
Ensembl chr14:45,062,662...45,081,991
JBrowse link
G Tnf tumor necrosis factor decreases secretion
multiple interactions
decreases expression
ISO
EXP
Glucosamine results in decreased secretion of TNF protein
Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
Glucosamine analog results in decreased expression of TNF mRNA; Glucosamine results in decreased expression of TNF mRNA
Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of TNF protein]; Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]
[Glucosamine co-treated with Chondroitin Sulfates] results in decreased expression of TNF; Alloxan inhibits the reaction [Glucosamine inhibits the reaction [TNF results in increased phosphorylation of RELA protein]]; Glucosamine analog inhibits the reaction [TNF results in increased expression of CUL2 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of GSPT1 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of RND1 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of TNFRSF1A mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of TNFRSF1B mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of TRAF6 mRNA]; Glucosamine inhibits the reaction [[IL6 co-treated with TNF] results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IFNG promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IL1B promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF promotes the reaction [IFNG results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF promotes the reaction [IL1B results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 protein]; Glucosamine inhibits the reaction [TNF results in increased expression of CUL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of GSPT1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of RND1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TNFRSF1A mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TNFRSF1B mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TRAF6 mRNA]; Glucosamine inhibits the reaction [TNF results in increased localization of RELA protein]; Glucosamine inhibits the reaction [TNF results in increased phosphorylation of RELA protein]
CTD PMID:14507305, PMID:16431966, PMID:16445576, PMID:16822504, PMID:17238806, PMID:18173918, PMID:18205790, PMID:18786831, PMID:19020780, PMID:19098112, PMID:20093129, PMID:20110869, PMID:20113495, PMID:20737476 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 multiple interactions
decreases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of TNFAIP6 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of TNFAIP6 mRNA] CTD PMID:17109745 NCBI chr 3:37,545,238...37,564,704
Ensembl chr 3:37,545,238...37,564,699
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B multiple interactions ISO [Chondroitin Sulfates co-treated with Glucosamine co-treated with Cholecalciferol] results in increased expression of TNFRSF11B mRNA; [Chondroitin Sulfates co-treated with Glucosamine co-treated with Cholecalciferol] results in increased expression of TNFRSF11B protein; [Chondroitin Sulfates co-treated with Glucosamine] results in increased expression of TNFRSF11B mRNA; [Chondroitin Sulfates co-treated with Glucosamine] results in increased expression of TNFRSF11B protein CTD PMID:17996099 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A multiple interactions ISO Glucosamine analog inhibits the reaction [TNF results in increased expression of TNFRSF1A mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TNFRSF1A mRNA] CTD PMID:18173918 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B multiple interactions ISO Glucosamine analog inhibits the reaction [TNF results in increased expression of TNFRSF1B mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TNFRSF1B mRNA] CTD PMID:18173918 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions
increases expression
ISO [Chondroitin Sulfates co-treated with Glucosamine] inhibits the reaction [Cholecalciferol results in increased expression of TNFSF11 mRNA]; Chondroitin Sulfates inhibits the reaction [Glucosamine results in increased expression of TNFSF11 mRNA] CTD PMID:17996099 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704
JBrowse link
G Tnk2 tyrosine kinase, non-receptor, 2 multiple interactions EXP Glucosamine inhibits the reaction [IL1B results in increased expression of TNK2 mRNA] CTD PMID:17109745 NCBI chr11:71,348,726...71,388,520
Ensembl chr11:71,348,717...71,387,992
JBrowse link
G Top2a DNA topoisomerase II alpha decreases expression EXP Glucosamine results in decreased expression of TOP2A mRNA CTD PMID:17109745 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
JBrowse link
G Traf6 TNF receptor associated factor 6 multiple interactions ISO Glucosamine analog inhibits the reaction [TNF results in increased expression of TRAF6 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TRAF6 mRNA] CTD PMID:18173918 NCBI chr 3:91,252,829...91,271,607
Ensembl chr 3:91,252,829...91,271,607
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 increases expression ISO Glucosamine results in increased expression of TRPV4 mRNA CTD PMID:17178593 NCBI chr12:47,698,915...47,737,902
Ensembl chr12:47,698,947...47,737,902
JBrowse link
G Txn1 thioredoxin 1 decreases expression EXP
ISO
Glucosamine results in decreased expression of TXN1 protein CTD PMID:17178593 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
G Txnip thioredoxin interacting protein increases expression
multiple interactions
EXP
ISO
Glucosamine results in increased expression of TXNIP protein
Glucosamine results in increased expression of TXNIP mRNA; Glucosamine results in increased expression of TXNIP protein
Glucosamine promotes the reaction [TXNIP results in increased abundance of Reactive Oxygen Species]; TXNIP promotes the reaction [Glucosamine results in increased expression of LAMB1 mRNA]; TXNIP promotes the reaction [Glucosamine results in increased expression of LAMC1 mRNA]
CTD PMID:17178593 NCBI chr 2:198,683,168...198,686,971
Ensembl chr 2:198,683,159...198,686,974
JBrowse link
G Ucp2 uncoupling protein 2 decreases expression EXP Glucosamine results in decreased expression of UCP2 mRNA CTD PMID:11893929 NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744
JBrowse link
G Uqcrh ubiquinol-cytochrome c reductase hinge protein increases expression ISO Glucosamine results in increased expression of UQCRH mRNA CTD PMID:17178593 NCBI chr 5:134,919,040...134,927,235
Ensembl chr 5:134,919,044...134,927,235
JBrowse link
G Vamp1 vesicle-associated membrane protein 1 increases expression EXP Glucosamine results in increased expression of VAMP1 mRNA CTD PMID:17109745 NCBI chr 4:157,726,941...157,733,644
Ensembl chr 4:157,726,941...157,733,643
JBrowse link
G Vcan versican multiple interactions
decreases expression
EXP Glucosamine inhibits the reaction [IL1B results in increased expression of VCAN mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of VCAN mRNA] CTD PMID:17109745 NCBI chr 2:18,490,102...18,587,340
Ensembl chr 2:18,490,102...18,565,842
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
increases expression
decreases expression
ISO
EXP
Glucosamine inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]
Glucosamine results in increased expression of VEGFA protein
Glucosamine results in decreased expression of VEGFA protein
CTD PMID:16324875, PMID:19254699 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vegfd vascular endothelial growth factor D increases expression
decreases expression
ISO
EXP
Glucosamine results in increased expression of VEGFD mRNA
Glucosamine results in decreased expression of VEGFD mRNA
CTD PMID:17109745, PMID:17178593 NCBI chr  X:31,816,480...31,852,239
Ensembl chr  X:31,816,436...31,851,715
JBrowse link
G Vnn1 vanin 1 increases expression ISO Glucosamine results in increased expression of VNN1 mRNA CTD PMID:17178593 NCBI chr 1:22,614,832...22,625,134
Ensembl chr 1:22,614,783...22,625,204
JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions
increases splicing
increases expression
decreases splicing
ISO
EXP
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA]; tauroursodeoxycholic acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA]
Glucosamine results in increased splicing of XBP1 mRNA
Glucosamine results in increased expression of XBP1 protein alternative form
4-methylumbelliferone 8-carbaldehyde affects the reaction [Glucosamine results in increased expression of XBP1 protein alternative form]; 4-methylumbelliferone 8-carbaldehyde inhibits the reaction [Glucosamine results in increased splicing of XBP1 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 protein alternative form]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased splicing of XBP1 mRNA]; ERN1 protein affects the reaction [Glucosamine results in increased splicing of XBP1 mRNA]
Glucosamine results in decreased splicing of XBP1 mRNA
CTD PMID:19383982, PMID:20165829, PMID:30602124 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
G Xdh xanthine dehydrogenase multiple interactions EXP [XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucosamine results in increased abundance of Proteoglycans]; [XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucosamine results in increased expression of B3GAT3 mRNA] CTD PMID:11801247 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
G Zfp467 zinc finger protein 467 increases expression ISO Glucosamine results in increased expression of ZFP467 mRNA CTD PMID:17178593 NCBI chr 4:78,068,822...78,077,962
Ensembl chr 4:78,067,689...78,075,398
JBrowse link
calycosin-7-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epo erythropoietin increases expression ISO calycosin-7-O-beta-D-glucoside results in increased expression of EPO mRNA CTD PMID:21309574 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression
ISO calycosin-7-O-beta-D-glucoside results in increased expression of and results in decreased degradation of HIF1A protein
calycosin-7-O-beta-D-glucoside results in increased expression of HIF1A mRNA
CTD PMID:21309574 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
cyanidin 3-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen multiple interactions ISO 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibits the reaction [cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in increased expression of NOS2 protein]]; cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in decreased expression of HMOX1 protein]; cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in increased degradation of NFKBIA protein]; cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in increased expression of and affects the localization of RELA protein]; cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in increased expression of NOS2 protein] CTD PMID:27983965 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases activity
ISO [cyanidin 3-O-glucoside results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA CTD PMID:23735880 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased phosphorylation of AKT1 protein] CTD PMID:21501596 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt2 AKT serine/threonine kinase 2 increases expression ISO cyanidin 3-O-glucoside results in increased expression of AKT2 mRNA CTD PMID:30597948 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162
JBrowse link
G Avp arginine vasopressin multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Cadmium Chloride results in increased expression of AVP mRNA] CTD PMID:31014900 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
ISO cyanidin 3-O-glucoside inhibits the reaction [Oxygen deficiency results in increased activity of CASP3 protein]
cyanidin 3-O-glucoside results in increased expression of CASP3 mRNA
CTD PMID:24518827, PMID:30597948 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases expression ISO cyanidin 3-O-glucoside results in increased expression of CASP8 mRNA CTD PMID:30597948 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Crem cAMP responsive element modulator multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Cadmium Chloride results in decreased expression of CREM protein] CTD PMID:31014900 NCBI chr17:57,021,704...57,090,888
Ensembl chr17:57,031,766...57,090,888
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Cadmium Chloride results in decreased expression of CYP11A1 protein] CTD PMID:31014900 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
increases expression
multiple interactions
ISO cyanidin 3-O-glucoside results in decreased activity of CYP1A1 protein
cyanidin 3-O-glucoside results in increased expression of CYP1A1 mRNA
[cyanidin 3-O-glucoside results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA
CTD PMID:23735880 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Cadmium Chloride results in increased secretion of FSHB protein] CTD PMID:31014900 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
JBrowse link
G Fshr follicle stimulating hormone receptor multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Cadmium Chloride results in decreased expression of FSHR mRNA] CTD PMID:31014900 NCBI chr 6:12,796,383...12,997,817
Ensembl chr 6:12,796,383...12,997,817
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase multiple interactions
affects binding
ISO [cyanidin 3-O-glucoside binds to FYN protein] which results in decreased activity of FYN protein; cyanidin 3-O-glucoside inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased activity of FYN protein] CTD PMID:21501596 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of GCLC mRNA CTD PMID:27818126 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions ISO cyanidin 3-O-glucoside promotes the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of GCLM mRNA] CTD PMID:27818126 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Cadmium Chloride results in increased expression of GNRH1 mRNA] CTD PMID:31014900 NCBI chr15:44,441,856...44,446,064
Ensembl chr15:44,442,555...44,442,875
Ensembl chr15:44,442,555...44,442,875
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
decreases expression
ISO cyanidin 3-O-glucoside inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]
cyanidin 3-O-glucoside results in decreased expression of HIF1A protein
CTD PMID:24518827 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO cyanidin 3-O-glucoside results in increased expression of HMOX1 mRNA
[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of HMOX1 mRNA; cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in decreased expression of HMOX1 protein]
CTD PMID:24518827, PMID:26422990, PMID:27793764, PMID:27818126, PMID:27983965 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Ifng interferon gamma multiple interactions ISO [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased activity of NFE2L2 protein; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of GCLC mRNA; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of HMOX1 mRNA; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of PPARG protein; cyanidin 3-O-glucoside promotes the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of GCLM mRNA]; Mesalamine inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of PPARG protein] CTD PMID:27818126 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased activity of NFE2L2 protein; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of GCLC mRNA; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of HMOX1 mRNA; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of PPARG protein; cyanidin 3-O-glucoside promotes the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of GCLM mRNA]; Mesalamine inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of PPARG protein] CTD PMID:27818126 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il6 interleukin 6 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased expression of IL6 mRNA] CTD PMID:27793764 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Kiss1 KiSS-1 metastasis-suppressor multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Cadmium Chloride results in increased expression of KISS1 mRNA] CTD PMID:31014900 NCBI chr13:50,529,506...50,537,603
Ensembl chr13:50,529,510...50,535,389
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions ISO [cyanidin 3-O-glucoside co-treated with Cadmium Chloride] results in increased secretion of LHB protein CTD PMID:31014900 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased phosphorylation of MAP2K4 protein] CTD PMID:21501596 NCBI chr10:52,196,121...52,301,887
Ensembl chr10:52,196,124...52,290,657
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased phosphorylation of MAPK1 protein] CTD PMID:21501596 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased phosphorylation of MAPK3 protein] CTD PMID:21501596 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Oxygen deficiency results in increased expression of and results in increased activity of MMP2 protein] CTD PMID:24518827 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases activity
multiple interactions
EXP
ISO
cyanidin 3-O-glucoside results in increased activity of NFE2L2 protein
[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased activity of NFE2L2 protein
CTD PMID:27166148, PMID:27818126 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in increased degradation of NFKBIA protein]; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased expression of NFKBIA protein modified form] CTD PMID:27793764, PMID:27983965 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibits the reaction [cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in increased expression of NOS2 protein]]; cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in increased expression of NOS2 protein] CTD PMID:27983965 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO cyanidin 3-O-glucoside results in increased expression of NQO1 mRNA CTD PMID:26422990, PMID:27793764 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha increases expression ISO cyanidin 3-O-glucoside results in increased expression of PIK3CA mRNA CTD PMID:30597948 NCBI chr 2:118,831,350...118,861,456
Ensembl chr 2:118,831,350...118,861,454
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 increases expression ISO cyanidin 3-O-glucoside results in increased expression of PIK3R1 mRNA CTD PMID:30597948 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of PPARG protein; Mesalamine inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of PPARG protein] CTD PMID:27818126 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Cadmium Chloride results in decreased expression of PRKACA protein] CTD PMID:31014900 NCBI chr19:25,095,089...25,118,869
Ensembl chr19:25,095,089...25,118,860
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of PTGS2 mRNA]; cyanidin 3-O-glucoside inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of PTGS2 protein]
cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]
CTD PMID:21501596, PMID:27793764 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO cyanidin 3-O-glucoside affects the localization of and results in decreased activity of RELA protein; cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in increased expression of and affects the localization of RELA protein]; cyanidin 3-O-glucoside inhibits the reaction [Palmitic Acid affects the localization of and results in increased activity of RELA protein] CTD PMID:26422990, PMID:27983965 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Sele selectin E multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Palmitic Acid results in increased expression of SELE mRNA]; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased expression of SELE protein] CTD PMID:26422990, PMID:30611791 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Cadmium Chloride results in decreased expression of STAR protein] CTD PMID:31014900 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression ISO cyanidin 3-O-glucoside results in increased expression of STAT3 mRNA CTD PMID:30597948 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased activity of NFE2L2 protein; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of GCLC mRNA; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of HMOX1 mRNA; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of PPARG protein; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in decreased abundance of Antioxidants]; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in decreased abundance of Glutathione]; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased abundance of Dinoprostone]; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased abundance of Thromboxane B2]; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased expression of NFKBIA protein modified form]; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased expression of SELE protein]; cyanidin 3-O-glucoside promotes the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of GCLM mRNA]; Mesalamine inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of PPARG protein] CTD PMID:27793764, PMID:27818126, PMID:30611791 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Palmitic Acid results in increased expression of VCAM1 mRNA] CTD PMID:26422990 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
daidzein 7-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase increases expression
multiple interactions
EXP daidzin results in increased expression of ACHE mRNA
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [daidzin results in increased expression of ACHE mRNA]; 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [daidzin results in increased expression of and results in increased activity of ACHE protein]; daidzin results in increased expression of and results in increased activity of ACHE protein
CTD PMID:31034797 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of ACSL3 mRNA CTD PMID:27424125 NCBI chr 9:84,569,601...84,593,565
Ensembl chr 9:84,569,597...84,593,565
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ALDH1A2 mRNA CTD PMID:27424125 NCBI chr 8:77,640,234...77,719,488
Ensembl chr 8:77,640,222...77,719,489
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions ISO daidzin inhibits the reaction [ALDH2 protein results in increased hydrolysis of 4-nitrophenyl acetate]; daidzin inhibits the reaction [ALDH2 protein results in increased oxidation of propionaldehyde] CTD PMID:21349255 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Anpep alanyl aminopeptidase, membrane multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ANPEP mRNA CTD PMID:27424125 NCBI chr 1:141,561,364...141,604,249
Ensembl chr 1:141,561,334...141,604,273
JBrowse link
G Atoh8 atonal bHLH transcription factor 8 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of ATOH8 mRNA CTD PMID:27424125 NCBI chr 4:100,067,341...100,099,517
Ensembl chr 4:100,067,341...100,099,517
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of BCKDK mRNA CTD PMID:27424125 NCBI chr 1:199,351,628...199,356,299
Ensembl chr 1:199,351,628...199,356,881
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO daidzin inhibits the reaction [Pentylenetetrazole results in decreased expression of BDNF protein] CTD PMID:32450180 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Bpgm bisphosphoglycerate mutase multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of BPGM mRNA CTD PMID:27424125 NCBI chr 4:61,912,210...61,940,697
Ensembl chr 4:61,912,210...61,940,696
JBrowse link
G Cabp5 calcium binding protein 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CABP5 mRNA CTD PMID:27424125 NCBI chr 1:75,693,216...75,706,069
Ensembl chr 1:75,693,232...75,706,069
JBrowse link
G Cacybp calcyclin binding protein multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CACYBP mRNA CTD PMID:27424125 NCBI chr13:77,948,771...77,959,089
Ensembl chr13:77,948,771...77,959,110
JBrowse link
G Casp8ap2 caspase 8 associated protein 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CASP8AP2 mRNA CTD PMID:27424125 NCBI chr 5:47,853,699...47,891,147
Ensembl chr 5:47,853,818...47,891,668
JBrowse link
G Cat catalase multiple interactions ISO daidzin inhibits the reaction [Pentylenetetrazole results in decreased activity of CAT protein] CTD PMID:32450180 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cd200r1 CD200 receptor 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CD200R1 mRNA CTD PMID:27424125 NCBI chr11:60,848,161...60,882,470
Ensembl chr11:60,848,131...60,882,379
JBrowse link
G Cfap251 cilia and flagella associated protein 251 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CFAP251 mRNA CTD PMID:27424125 NCBI chr12:38,708,915...38,781,598
Ensembl chr12:38,709,595...38,782,010
JBrowse link
G Cybrd1 cytochrome b reductase 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CYBRD1 mRNA CTD PMID:27424125 NCBI chr 3:57,718,496...57,745,749
Ensembl chr 3:57,718,364...57,746,097
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of CYP11A1 mRNA CTD PMID:28964809 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Dennd2d DENN domain containing 2D multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of DENND2D mRNA CTD PMID:27424125 NCBI chr 2:209,097,894...209,116,978
Ensembl chr 2:209,097,927...209,116,965
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT1 mRNA CTD PMID:28964809 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT3A mRNA CTD PMID:28964809 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577
JBrowse link
G Dpp9 dipeptidyl peptidase 9 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of DPP9 mRNA CTD PMID:27424125 NCBI chr 9:10,846,493...10,882,560
Ensembl chr 9:10,846,596...10,882,649
JBrowse link
G Edrf1 erythroid differentiation regulatory factor 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of EDRF1 mRNA CTD PMID:27424125 NCBI chr 1:205,706,023...205,743,676
Ensembl chr 1:205,706,468...205,743,653
JBrowse link
G Efhd1 EF-hand domain family, member D1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of EFHD1 mRNA CTD PMID:27424125 NCBI chr 9:94,362,249...94,408,884
Ensembl chr 9:94,362,299...94,408,885
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of ESR2 mRNA CTD PMID:28964809 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Fam171a2 family with sequence similarity 171, member A2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FAM171A2 mRNA CTD PMID:27424125 NCBI chr10:90,383,111...90,393,476
Ensembl chr10:90,383,813...90,393,317
JBrowse link
G Fam180a family with sequence similarity 180, member A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM180A mRNA CTD PMID:27424125 NCBI chr 4:62,845,054...62,860,361
Ensembl chr 4:62,844,971...62,860,446
JBrowse link
G Fam210b family with sequence similarity 210, member B multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM210B mRNA CTD PMID:27424125 NCBI chr 3:170,354,109...170,364,265
Ensembl chr 3:170,354,141...170,362,513
JBrowse link
G Fam241b family with sequence similarity 241 member B multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of FAM241B mRNA CTD PMID:27424125 NCBI chr20:31,734,297...31,736,115
Ensembl chr20:31,734,183...31,736,212
JBrowse link
G Fgd6 FYVE, RhoGEF and PH domain containing 6 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FGD6 mRNA CTD PMID:27424125 NCBI chr 7:34,951,878...35,063,006
Ensembl chr 7:34,952,011...35,063,929
JBrowse link
G Fhl2 four and a half LIM domains 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FHL2 mRNA CTD PMID:27424125 NCBI chr 9:49,920,611...49,994,906
Ensembl chr 9:49,920,854...49,950,093
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO daidzin results in increased expression of FOS mRNA CTD PMID:17142977 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Galnt15 polypeptide N-acetylgalactosaminyltransferase 15 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of GALNT15 mRNA CTD PMID:27424125 NCBI chr16:8,127,599...8,178,101
Ensembl chr16:8,128,689...8,177,841
JBrowse link
G Gng5 G protein subunit gamma 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of GNG5 mRNA CTD PMID:27424125 NCBI chr 2:252,359,976...252,368,473
Ensembl chr 2:252,359,976...252,368,473
JBrowse link
G Hipk4 homeodomain interacting protein kinase 4 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of HIPK4 mRNA CTD PMID:27424125 NCBI chr 1:84,328,114...84,338,486
Ensembl chr 1:84,328,114...84,338,483
JBrowse link
G Hmcn1 hemicentin 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of HMCN1 mRNA CTD PMID:27424125 NCBI chr13:67,799,791...68,360,664
Ensembl chr13:67,799,791...68,360,664
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO daidzin inhibits the reaction [Pentylenetetrazole results in decreased expression of HMOX1 protein] CTD PMID:32450180 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of HSD3B1 mRNA CTD PMID:28964809
G Il6r interleukin 6 receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of IL6R mRNA CTD PMID:27424125 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Isg20l2 interferon stimulated exonuclease gene 20-like 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ISG20L2 mRNA CTD PMID:27424125 NCBI chr 2:187,302,192...187,311,677
Ensembl chr 2:187,302,192...187,311,676
JBrowse link
G Kdm5a lysine demethylase 5A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of KDM5A mRNA CTD PMID:27424125 NCBI chr 4:152,892,388...152,972,196
Ensembl chr 4:152,892,388...152,972,201
JBrowse link
G Kitlg KIT ligand multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KITLG mRNA CTD PMID:27424125 NCBI chr 7:42,269,784...42,351,054
Ensembl chr 7:42,269,784...42,351,054
JBrowse link
G Knstrn kinetochore-localized astrin/SPAG5 binding protein multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KNSTRN mRNA CTD PMID:27424125 NCBI chr 3:110,618,256...110,638,024
Ensembl chr 3:110,618,298...110,638,046
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LDLRAP1 mRNA CTD PMID:27424125 NCBI chr 5:152,964,294...152,987,286
Ensembl chr 5:152,966,591...152,987,211
JBrowse link
G Lmod1 leiomodin 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LMOD1 mRNA CTD PMID:27424125 NCBI chr13:52,147,099...52,189,835
Ensembl chr13:52,147,555...52,190,228
JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of LRG1 mRNA CTD PMID:27424125 NCBI chr 9:10,952,424...10,954,664
Ensembl chr 9:10,952,374...10,954,681
JBrowse link
G Lsr lipolysis stimulated lipoprotein receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LSR mRNA CTD PMID:27424125 NCBI chr 1:89,383,515...89,399,041
Ensembl chr 1:89,383,519...89,399,041
JBrowse link
G Mrpl33 mitochondrial ribosomal protein L33 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of MRPL33 mRNA CTD PMID:27424125 NCBI chr 6:26,130,278...26,138,498
Ensembl chr 6:26,130,488...26,138,414
JBrowse link
G Mtmr11 myotubularin related protein 11 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of MTMR11 mRNA CTD PMID:27424125 NCBI chr 2:198,301,666...198,311,787
Ensembl chr 2:198,303,168...198,311,785
JBrowse link
G Myof myoferlin multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of MYOF mRNA CTD PMID:27424125 NCBI chr 1:256,585,410...256,734,727
Ensembl chr 1:256,585,410...256,734,730
JBrowse link
G Nefh neurofilament heavy increases expression EXP daidzin results in increased expression of NEFH mRNA; daidzin results in increased expression of NEFH protein CTD PMID:31034797 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Nefl neurofilament light increases expression EXP daidzin results in increased expression of NEFL mRNA; daidzin results in increased expression of NEFL protein CTD PMID:31034797 NCBI chr15:44,799,378...44,803,251
Ensembl chr15:44,799,334...44,804,574
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of NR4A1 mRNA CTD PMID:27424125 NCBI chr 7:142,899,358...142,920,216
Ensembl chr 7:142,905,758...142,920,216
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 protein; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased methylation of NR5A1 promoter; decitabine inhibits the reaction [[Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA] CTD PMID:28964809 NCBI chr 3:22,998,900...23,020,441
Ensembl chr 3:22,999,616...23,020,441
JBrowse link
G Pgr progesterone receptor increases expression ISO daidzin results in increased expression of PGR protein CTD PMID:17142977 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Prima1 proline rich membrane anchor 1 increases expression
multiple interactions
EXP daidzin results in increased expression of PRIMA1 mRNA
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [daidzin results in increased expression of PRIMA1 mRNA]
CTD PMID:31034797 NCBI chr 6:127,075,954...127,127,985
Ensembl chr 6:127,075,954...127,127,413
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of PRKACA mRNA CTD PMID:27424125 NCBI chr19:25,095,089...25,118,869
Ensembl chr19:25,095,089...25,118,860
JBrowse link
G Prpf40a pre-mRNA processing factor 40 homolog A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PRPF40A mRNA CTD PMID:27424125 NCBI chr 3:38,680,583...38,741,570
Ensembl chr 3:38,682,146...38,741,113
JBrowse link
G Pspc1 paraspeckle component 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PSPC1 mRNA CTD PMID:27424125 NCBI chr15:36,946,914...37,030,273
Ensembl chr15:36,950,257...37,030,281
JBrowse link
G Pth1r parathyroid hormone 1 receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of PTH1R mRNA CTD PMID:27424125 NCBI chr 8:118,984,531...119,012,803
Ensembl chr 8:118,988,053...119,012,671
JBrowse link
G Rassf5 Ras association domain family member 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of RASSF5 mRNA CTD PMID:27424125 NCBI chr13:47,956,754...48,022,333
Ensembl chr13:47,956,790...48,022,333
JBrowse link
G Rgs22 regulator of G-protein signaling 22 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of RGS22 mRNA CTD PMID:27424125 NCBI chr 7:74,783,009...74,902,049
Ensembl chr 7:74,783,019...74,901,997
JBrowse link
G S1pr3 sphingosine-1-phosphate receptor 3 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of S1PR3 mRNA CTD PMID:27424125 NCBI chr17:13,799,383...13,812,877
Ensembl chr17:13,799,383...13,812,704
JBrowse link
G Selplg selectin P ligand multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SELPLG mRNA CTD PMID:27424125 NCBI chr12:48,577,905...48,579,196
Ensembl chr12:48,577,905...48,579,196
JBrowse link
G Siglec10 sialic acid binding Ig-like lectin 10 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of SIGLEC10 mRNA CTD PMID:27424125 NCBI chr 1:98,512,663...98,521,736
Ensembl chr 1:98,512,625...98,521,706
JBrowse link
G Slc16a1 solute carrier family 16 member 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SLC16A1 mRNA CTD PMID:27424125 NCBI chr 2:207,108,552...207,129,352
Ensembl chr 2:207,108,552...207,128,554
JBrowse link
G Snx30 sorting nexin family member 30 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of SNX30 mRNA CTD PMID:27424125 NCBI chr 5:77,052,445...77,161,964
Ensembl chr 5:77,052,484...77,157,915
JBrowse link
G Ssc5d scavenger receptor cysteine rich family member with 5 domains multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SSC5D mRNA CTD PMID:27424125 NCBI chr 1:72,443,750...72,462,293
Ensembl chr 1:72,443,758...72,461,547
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR protein CTD PMID:28964809 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of STYXL1 mRNA CTD PMID:27424125 NCBI chr12:23,954,563...23,987,155
Ensembl chr12:23,954,574...23,987,271
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of SUMO1 mRNA CTD PMID:27424125 NCBI chr 9:66,453,428...66,483,614
Ensembl chr 9:66,453,438...66,483,614
JBrowse link
G Tc2n tandem C2 domains, nuclear multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of TC2N mRNA CTD PMID:27424125 NCBI chr 6:125,437,767...125,601,408
Ensembl chr 6:125,437,775...125,590,049
JBrowse link
G Tp53i11 tumor protein p53 inducible protein 11 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of TP53I11 mRNA CTD PMID:27424125 NCBI chr 3:82,081,838...82,097,064
Ensembl chr 3:82,081,906...82,097,056
JBrowse link
G Vcpip1 valosin containing protein interacting protein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of VCPIP1 mRNA CTD PMID:27424125 NCBI chr 5:9,231,180...9,257,821
Ensembl chr 5:9,230,984...9,257,934
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO daidzin inhibits the reaction [Pentylenetetrazole results in increased expression of VEGFA protein] CTD PMID:32450180 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
etoposide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A affects response to substance
multiple interactions
increases expression
ISO ABCB1 exon polymorphism affects the susceptibility to Etoposide
[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [Celecoxib results in decreased expression of ABCB1] which results in increased susceptibility to Etoposide
Etoposide results in increased expression of ABCB1 mRNA; Etoposide results in increased expression of ABCB1 protein
CTD PMID:12969965, PMID:15239124, PMID:19047049, PMID:19562670, PMID:27570640, PMID:27840903 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 affects response to substance
decreases response to substance
multiple interactions
decreases uptake
increases expression
ISO ABCC1 protein affects the susceptibility to Etoposide
ABCC1 protein results in decreased susceptibility to Etoposide; ABCC1 results in decreased susceptibility to Etoposide
[GCLC protein co-treated with GCLM protein] promotes the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; [MYCN protein affects the expression of ABCC1 mRNA] which affects the susceptibility to Etoposide; GSTP1 protein promotes the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; hesperetin inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; naringenin inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; Resveratrol inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; Silymarin inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; Tocopherols inhibits the reaction [ABCC1 protein affects the export of Etoposide]; verlukast inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]
ABCC1 protein results in decreased uptake of Etoposide
Etoposide results in increased expression of ABCC1 mRNA
Glucose inhibits the reaction [Sodium Azide inhibits the reaction [ABCC1 protein results in decreased uptake of Etoposide]]; Sodium Azide inhibits the reaction [ABCC1 protein results in decreased uptake of Etoposide]; Verapamil inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; Verapamil inhibits the reaction [ABCC1 protein results in decreased uptake of Etoposide]
CTD PMID:7954421, PMID:8968083, PMID:9334814, PMID:10348353, PMID:10856430, PMID:10900222, PMID:11778547, PMID:15180633, PMID:15460906, PMID:15617835, PMID:15999103, PMID:16156793, PMID:16217747 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 affects transport
multiple interactions
ISO ABCC2 protein affects the transport of Etoposide
Probenecid promotes the reaction [ABCC2 protein affects the transport of Etoposide]
CTD PMID:15751272, PMID:15849751 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 decreases response to substance ISO ABCC3 protein results in decreased susceptibility to Etoposide CTD PMID:15884115 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO [ERBB2 results in increased expression of ABCG2] which results in decreased susceptibility to Etoposide; ABCG2 mutant form inhibits the reaction [ERBB2 results in decreased susceptibility to Etoposide] CTD PMID:21712253 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Abhd4 abhydrolase domain containing 4, N-acyl phospholipase B increases expression ISO Etoposide results in increased expression of ABHD4 mRNA CTD PMID:25270620 NCBI chr15:32,888,233...32,906,861
Ensembl chr15:32,894,938...32,906,850
JBrowse link
G Abra actin-binding Rho activating protein increases expression ISO Etoposide results in increased expression of ABRA mRNA CTD PMID:29397400 NCBI chr 7:80,792,615...80,796,683
Ensembl chr 7:80,792,600...80,796,670
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain affects response to substance ISO ACADM protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:260,124,418...260,148,589
Ensembl chr 2:260,124,418...260,148,589
JBrowse link
G Ace2 angiotensin I converting enzyme 2 increases expression ISO Etoposide results in increased expression of ACE2 mRNA CTD PMID:29397400 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Aco1 aconitase 1 increases expression ISO Etoposide results in increased expression of ACO1 mRNA CTD PMID:25270620 NCBI chr 5:56,425,076...56,481,218
Ensembl chr 5:56,425,024...56,481,218
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 affects response to substance ISO ACSL3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 9:84,569,601...84,593,565
Ensembl chr 9:84,569,597...84,593,565
JBrowse link
G Acta1 actin, alpha 1, skeletal muscle decreases expression ISO Etoposide results in decreased expression of ACTA1 mRNA CTD PMID:29397400 NCBI chr19:56,674,072...56,677,084
Ensembl chr19:56,674,074...56,677,084
JBrowse link
G Agrn agrin increases expression ISO Etoposide results in increased expression of AGRN mRNA CTD PMID:17374387 NCBI chr 5:173,589,910...173,622,813
Ensembl chr 5:173,589,819...173,622,645
JBrowse link
G Ahcyl1 adenosylhomocysteinase-like 1 affects response to substance ISO AHCYL1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:210,438,884...210,474,350
Ensembl chr 2:210,438,893...210,473,761
JBrowse link
G Ahi1 Abelson helper integration site 1 increases expression ISO Etoposide results in increased expression of AHI1 protein alternative form CTD PMID:19379585 NCBI chr 1:16,478,127...16,601,769
Ensembl chr 1:16,478,127...16,601,769
JBrowse link
G Akap12 A-kinase anchoring protein 12 affects response to substance ISO AKAP12 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:40,816,130...40,906,582
Ensembl chr 1:40,816,107...40,906,581
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases response to substance
increases phosphorylation
multiple interactions
ISO AKT1 protein modified form results in increased susceptibility to Etoposide
Etoposide results in increased phosphorylation of AKT1 protein
Etoposide results in increased phosphorylation of and results in increased activity of AKT1 protein; pepstatin inhibits the reaction [AKT1 protein modified form results in increased susceptibility to Etoposide]; PTEN protein inhibits the reaction [Etoposide results in increased phosphorylation of and results in increased activity of AKT1 protein]
CTD PMID:17699715, PMID:17935137, PMID:27769712 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alad aminolevulinate dehydratase multiple interactions ISO [Cyclophosphamide co-treated with Carmustine co-treated with Etoposide] results in decreased activity of ALAD protein CTD PMID:19162187 NCBI chr 5:78,368,867...78,379,206
Ensembl chr 5:78,368,867...78,379,346
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 increases expression ISO Etoposide results in increased expression of ALAS1 mRNA CTD PMID:25270620 NCBI chr 8:114,927,704...114,941,038
Ensembl chr 8:114,927,722...114,940,177
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 affects response to substance ISO ALDH3A1 protein affects the susceptibility to Etoposide CTD PMID:15905174 NCBI chr10:47,490,168...47,499,855
Ensembl chr10:47,490,153...47,499,876
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C affects response to substance
multiple interactions
ISO ALDOC protein affects the susceptibility to Etoposide
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ALDOC protein
CTD PMID:16217747, PMID:29733421 NCBI chr10:65,586,504...65,590,093
Ensembl chr10:65,586,504...65,590,126
JBrowse link
G Alpg alkaline phosphatase, germ cell affects response to substance ISO ALPG protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 9:94,164,667...94,184,972
Ensembl chr 9:94,178,221...94,181,010
JBrowse link
G Alpp alkaline phosphatase, placental affects response to substance ISO ALPP protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 9:94,189,961...94,193,054
Ensembl chr 9:94,190,067...94,192,813
JBrowse link
G Ank1 ankyrin 1 increases expression ISO Etoposide results in increased expression of ANK1 mRNA CTD PMID:29397400 NCBI chr16:73,681,422...73,912,605
Ensembl chr16:73,681,422...73,827,488
JBrowse link
G Ankrd10 ankyrin repeat domain 10 decreases expression ISO Etoposide results in decreased expression of ANKRD10 mRNA CTD PMID:21527772 NCBI chr16:83,205,898...83,229,147
Ensembl chr16:83,206,004...83,228,194
JBrowse link
G Ankrd27 ankyrin repeat domain 27 decreases expression ISO Etoposide results in decreased expression of ANKRD27 mRNA CTD PMID:25270620 NCBI chr 1:91,857,048...91,958,763
Ensembl chr 1:91,857,057...91,958,763
JBrowse link
G Ankrd28 ankyrin repeat domain 28 affects response to substance ISO ANKRD28 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr16:7,816,876...7,879,023
Ensembl chr16:7,818,667...7,928,518
JBrowse link
G Anxa4 annexin A4 increases expression ISO Etoposide results in increased expression of ANXA4 mRNA CTD PMID:17374387 NCBI chr 4:118,538,775...118,595,591
Ensembl chr 4:118,538,777...118,595,580
JBrowse link
G Anxa7 annexin A7 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ANXA7 protein CTD PMID:29733421 NCBI chr15:4,254,470...4,281,296
Ensembl chr15:4,254,499...4,281,287
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO Etoposide results in increased expression of APAF1 mRNA CTD PMID:25270620 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 decreases response to substance ISO APEX1 protein results in decreased susceptibility to Etoposide CTD PMID:20856196 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Aplp1 amyloid beta precursor like protein 1 decreases expression ISO Etoposide results in decreased expression of APLP1 mRNA CTD PMID:25270620 NCBI chr 1:88,897,525...88,908,750
Ensembl chr 1:88,897,532...88,908,750
JBrowse link
G Aqp1 aquaporin 1 decreases expression ISO Etoposide results in decreased expression of AQP1 mRNA CTD PMID:25270620 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Ar androgen receptor multiple interactions
increases degradation
ISO calpain inhibitor 2 inhibits the reaction [Etoposide results in increased degradation of AR protein]; CAST inhibits the reaction [Etoposide results in increased degradation of AR protein]; Etoposide inhibits the reaction [Androgens results in increased activity of AR protein]; Etoposide inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:18726991, PMID:28377212, PMID:30818834 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Areg amphiregulin increases expression
decreases expression
ISO Etoposide results in increased expression of AREG mRNA; Etoposide results in increased expression of AREG protein
Etoposide results in decreased expression of AREG mRNA
CTD PMID:15228094, PMID:25270620 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Arg2 arginase 2 decreases expression ISO Etoposide results in decreased expression of ARG2 mRNA CTD PMID:29397400 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta increases expression ISO Etoposide results in increased expression of ARHGDIB mRNA CTD PMID:21527772 NCBI chr 4:170,913,920...170,932,789
Ensembl chr 4:170,913,923...170,932,618
JBrowse link
G Arih1 ariadne RBR E3 ubiquitin protein ligase 1 increases response to substance ISO ARIH1 mutant form results in increased susceptibility to Etoposide CTD PMID:25624349 NCBI chr 8:64,166,359...64,268,555
Ensembl chr 8:64,166,360...64,268,555
JBrowse link
G Arl6ip5 ADP-ribosylation factor like GTPase 6 interacting protein 5 increases response to substance
decreases expression
ISO ARL6IP5 protein results in increased susceptibility to Etoposide
Etoposide results in decreased expression of ARL6IP5
CTD PMID:19492242 NCBI chr 4:129,574,363...129,598,240
Ensembl chr 4:129,574,264...129,598,915
JBrowse link
G Arsa arylsulfatase A decreases expression ISO Etoposide results in decreased expression of ARSA mRNA CTD PMID:25270620 NCBI chr 7:130,446,644...130,452,632
Ensembl chr 7:130,446,668...130,451,283
JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 affects response to substance ISO ASAH1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr16:53,998,604...54,030,006
Ensembl chr16:53,998,560...54,040,836
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions ISO Etoposide results in increased phosphorylation of and results in increased activity of ATF2 protein CTD PMID:12663670 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
JBrowse link
G Atf4 activating transcription factor 4 decreases expression ISO Etoposide results in decreased expression of ATF4 mRNA CTD PMID:25270620 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atm ATM serine/threonine kinase multiple interactions ISO Etoposide results in increased phosphorylation of and results in increased activity of ATM protein
Etoposide results in increased phosphorylation of and affects the localization of ATM protein; pifithrin inhibits the reaction [Etoposide results in increased phosphorylation of and affects the localization of ATM protein]
CTD PMID:22242153, PMID:26259609 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atp13a4 ATPase 13A4 decreases expression ISO Etoposide results in decreased expression of ATP13A4 mRNA CTD PMID:25270620 NCBI chr11:74,833,824...74,968,160
Ensembl chr11:74,834,050...74,968,336
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 affects response to substance ISO ATP1A1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023
JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 decreases expression ISO Etoposide results in decreased expression of ATP1A2 mRNA CTD PMID:29397400 NCBI chr13:90,651,682...90,676,629
Ensembl chr13:90,651,686...90,676,629
JBrowse link
G Atp1b4 ATPase Na+/K+ transporting family member beta 4 increases expression ISO Etoposide results in increased expression of ATP1B4 mRNA CTD PMID:29397400 NCBI chr  X:124,631,544...124,652,520
Ensembl chr  X:124,631,881...124,652,975
JBrowse link
G Atp5me ATP synthase membrane subunit e multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in increased expression of ATP5ME protein CTD PMID:29733421 NCBI chr14:2,325,308...2,326,436
Ensembl chr14:2,325,308...2,326,436
JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP decreases expression ISO Etoposide results in decreased expression of ATP5O protein CTD PMID:29733421 NCBI chr11:32,081,606...32,087,918
Ensembl chr11:32,081,574...32,088,002
JBrowse link
G Atp6v0a4 ATPase H+ transporting V0 subunit a4 affects response to substance ISO ATP6V0A4 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:65,736,585...65,821,916
Ensembl chr 4:65,736,585...65,818,521
JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A multiple interactions
decreases expression
ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ATP6V1A protein
Etoposide results in decreased expression of ATP6V1A protein
CTD PMID:29733421 NCBI chr11:61,531,386...61,584,634
Ensembl chr11:61,531,416...61,584,634
JBrowse link
G Atp7a ATPase copper transporting alpha decreases response to substance ISO ATP7A protein results in decreased susceptibility to Etoposide CTD PMID:17510416 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644
JBrowse link
G Atr ATR serine/threonine kinase increases phosphorylation ISO Etoposide results in increased phosphorylation of ATR protein CTD PMID:22242153 NCBI chr 8:103,673,578...103,770,886
Ensembl chr 8:103,673,411...103,770,947
JBrowse link
G Atxn1 ataxin 1 decreases expression ISO Etoposide results in decreased expression of ATXN1 mRNA CTD PMID:24211769 NCBI chr17:19,160,986...19,533,814
Ensembl chr17:19,249,952...19,533,814
JBrowse link
G Aurka aurora kinase A decreases expression ISO Etoposide results in decreased expression of AURKA mRNA CTD PMID:25270620 NCBI chr 3:170,364,177...170,380,278
Ensembl chr 3:170,364,181...170,378,210
JBrowse link
G Avpi1 arginine vasopressin-induced 1 affects response to substance ISO AVPI1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:261,365,590...261,371,519
Ensembl chr 1:261,365,590...261,371,508
JBrowse link
G Avpr1a arginine vasopressin receptor 1A increases expression ISO Etoposide results in increased expression of AVPR1A mRNA CTD PMID:29397400 NCBI chr 7:67,341,366...67,345,290
Ensembl chr 7:67,341,080...67,345,308
JBrowse link
G Axl Axl receptor tyrosine kinase increases expression ISO Etoposide results in increased expression of AXL mRNA CTD PMID:21527772 NCBI chr 1:82,550,892...82,580,761
Ensembl chr 1:82,549,420...82,580,761
JBrowse link
G Bace2 beta-secretase 2 affects response to substance ISO BACE2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr11:37,798,397...37,880,624
Ensembl chr11:37,798,370...37,880,821
JBrowse link
G Bag2 BAG cochaperone 2 affects response to substance ISO BAG2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 9:38,456,487...38,467,120
Ensembl chr 9:38,456,468...38,467,118
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases activity
increases response to substance
affects response to substance
multiple interactions
affects expression
ISO Etoposide results in increased activity of BAK1 protein
BAK1 protein results in increased susceptibility to Etoposide
BAK1 protein affects the susceptibility to Etoposide
nimesulide inhibits the reaction [Etoposide results in increased activity of BAK1 protein]
Etoposide affects the expression of BAK1 protein
CTD PMID:15215046, PMID:16077961, PMID:17688235, PMID:21745461 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor affects response to substance ISO BAMBI protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr17:56,905,419...56,909,675
Ensembl chr17:56,905,112...56,909,992
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
decreases folding
affects response to substance
ISO [ABT-737 co-treated with Etoposide] affects the folding of and results in increased activity of BAX protein; [Cisplatin co-treated with Etoposide] affects the localization of BAX protein; [Doxorubicin co-treated with Vincristine co-treated with Etoposide co-treated with Mitotane] results in decreased expression of BAX protein; [IL4 protein co-treated with VCAM1 protein] inhibits the reaction [Etoposide results in decreased folding of BAX protein]; [RASSF1 co-treated with Etoposide] affects the folding of and results in increased activity of BAX protein; [VCAM1 protein co-treated with IL4 protein] inhibits the reaction [Etoposide inhibits the reaction [BAX protein binds to BCL2L1 protein]]; Etoposide inhibits the reaction [BAX protein binds to BCL2L1 protein]; Etoposide results in increased activity of and affects the localization of BAX protein; Etoposide results in increased cleavage of and results in increased expression of BAX protein; Nicotine inhibits the reaction [[Cisplatin co-treated with Etoposide] affects the localization of BAX protein]; nimesulide inhibits the reaction [Etoposide results in increased activity of and affects the localization of BAX protein]
Etoposide results in increased expression of BAX mRNA; Etoposide results in increased expression of BAX protein
BAX protein affects the susceptibility to Etoposide
CTD PMID:9815696, PMID:10620629, PMID:15131059, PMID:16077961, PMID:16120219, PMID:18676776, PMID:21527772, PMID:21745461, PMID:21880625, PMID:29397400 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression
multiple interactions
affects response to substance
ISO Etoposide results in increased expression of BBC3 mRNA; Etoposide results in increased expression of BBC3 protein
entinostat promotes the reaction [Etoposide results in increased expression of BBC3 protein]; Etoposide promotes the reaction [entinostat results in increased expression of BBC3 protein]; Etoposide promotes the reaction [trichostatin A results in increased expression of BBC3 protein]; Etoposide promotes the reaction [UF010 compound results in increased expression of BBC3 protein]; trichostatin A promotes the reaction [Etoposide results in increased expression of BBC3 protein]; UF010 compound promotes the reaction [Etoposide results in increased expression of BBC3 protein]
BBC3 protein affects the susceptibility to Etoposide
CTD PMID:20477944, PMID:21801448, PMID:25699604 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
ISO [Doxorubicin co-treated with Vincristine co-treated with Etoposide co-treated with Mitotane] results in decreased expression of BCL2 protein; [Etoposide co-treated with Ciprofloxacin] results in decreased expression of BCL2 protein; BCL2 protein inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; BCL2 protein inhibits the reaction [Etoposide results in increased degradation of PARP1 protein]; BCL2 protein results in decreased susceptibility to [Cisplatin co-treated with Etoposide]
Etoposide results in decreased expression of BCL2 mRNA; Etoposide results in decreased expression of BCL2 protein
[G(M3) Ganglioside results in increased expression of BCL2 protein] which results in decreased susceptibility to Etoposide; BCL2 protein affects the reaction [[Etoposide results in increased activity of GSK3B protein] which results in increased activity of CASP3 protein]; Lithium Chloride inhibits the reaction [Etoposide results in decreased expression of BCL2 mRNA]; Lithium Chloride inhibits the reaction [Etoposide results in decreased expression of BCL2 protein]
CTD PMID:8840993, PMID:9815696, PMID:12063570, PMID:15917659, PMID:16571667, PMID:19408126 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
affects expression
decreases response to substance
ISO [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [VCAM1 protein co-treated with IL4 protein] inhibits the reaction [Etoposide inhibits the reaction [BAX protein binds to BCL2L1 protein]]; BCL2L1 protein inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; BCL2L1 protein inhibits the reaction [Etoposide results in increased degradation of PARP1 protein]; BCL2L1 protein results in decreased susceptibility to [Cisplatin co-treated with Etoposide]; Etoposide inhibits the reaction [BAX protein binds to BCL2L1 protein]
Etoposide affects the expression of BCL2L1 protein
BCL2L1 protein results in decreased susceptibility to Etoposide
CTD PMID:8840993, PMID:10620629, PMID:11468182, PMID:15215046, PMID:15917659, PMID:19047049 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl2l2 Bcl2-like 2 decreases response to substance ISO BCL2L2 results in decreased susceptibility to Etoposide CTD PMID:14973057 NCBI chr15:33,543,774...33,549,165
Ensembl chr15:33,544,312...33,549,164
JBrowse link
G Bcl6b BCL6B, transcription repressor multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of BCL6B mRNA CTD PMID:29733421 NCBI chr10:56,834,363...56,840,058
Ensembl chr10:56,834,364...56,839,437
JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression
multiple interactions
ISO Etoposide results in increased expression of BDNF mRNA
HIPK2 mutant form inhibits the reaction [Etoposide results in increased expression of BDNF mRNA]
CTD PMID:20573984 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions
increases expression
increases cleavage
ISO CASP9 mutant form inhibits the reaction [Etoposide results in increased cleavage of BID protein]; Estradiol inhibits the reaction [Etoposide results in increased expression of BID mRNA] CTD PMID:19426747, PMID:21801448 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Bik BCL2-interacting killer increases response to substance ISO BIK protein results in increased susceptibility to Etoposide CTD PMID:16007125 NCBI chr 7:124,390,924...124,410,449
Ensembl chr 7:124,391,432...124,410,447
JBrowse link
G Bin1 bridging integrator 1 increases response to substance ISO BIN1 protein results in increased susceptibility to Etoposide CTD PMID:21447800 NCBI chr18:25,163,575...25,222,139
Ensembl chr18:25,163,561...25,222,135
JBrowse link
G Bin3 bridging integrator 3 affects response to substance ISO BIN3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr15:51,799,339...51,818,697
Ensembl chr15:51,779,839...51,818,699
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 affects response to substance
decreases response to substance
increases expression
ISO BIRC2 protein affects the susceptibility to Etoposide
BIRC2 protein results in decreased susceptibility to Etoposide
Etoposide results in increased expression of BIRC2 mRNA
CTD PMID:10815900, PMID:14970392, PMID:15050749, PMID:16217747 NCBI chr 8:6,014,014...6,036,668
Ensembl chr 8:6,013,207...6,034,142
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases response to substance
decreases expression
multiple interactions
ISO BIRC3 protein results in decreased susceptibility to Etoposide
Etoposide results in decreased expression of BIRC3 mRNA
[Etoposide co-treated with KN 62] results in decreased expression of BIRC3 protein
CTD PMID:14666661, PMID:15050749, PMID:16120219 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
decreases response to substance
increases expression
ISO [FOXO3 protein results in decreased expression of BIRC5 protein] which results in increased susceptibility to Etoposide; BIRC5 protein inhibits the reaction [FOXO3 protein results in increased susceptibility to Etoposide]; BIRC5 protein results in decreased susceptibility to [Cisplatin co-treated with Etoposide]; Estradiol inhibits the reaction [Etoposide results in increased expression of BIRC5 mRNA]
BIRC5 protein results in decreased susceptibility to Etoposide
CTD PMID:15917659, PMID:16322251, PMID:16364925, PMID:16382892, PMID:19211844, PMID:19426747 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Birc7 baculoviral IAP repeat-containing 7 decreases response to substance ISO BIRC7 protein results in decreased susceptibility to Etoposide CTD PMID:17437058 NCBI chr 3:176,438,335...176,443,864
Ensembl chr 3:176,439,199...176,443,195
JBrowse link
G Blm BLM RecQ like helicase decreases expression ISO Etoposide results in decreased expression of BLM mRNA CTD PMID:24211769 NCBI chr 1:142,246,773...142,332,616
Ensembl chr 1:142,246,790...142,332,588
JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions ISO Etoposide inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA] CTD PMID:25633564 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Brca1 BRCA1, DNA repair associated multiple interactions
increases expression
decreases expression
ISO BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of CDK2 protein]; BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of RAD52 protein]; BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of RAD54L protein]; BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of XRCC2 protein]; BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of XRCC3 protein]; BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of XRCC4 protein]; pifithrin inhibits the reaction [Etoposide results in increased expression of and affects the localization of BRCA1 protein]
Etoposide results in increased expression of BRCA1 protein
Etoposide results in decreased expression of BRCA1 mRNA
CTD PMID:15607317, PMID:16417649, PMID:26259609 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin increases expression ISO Etoposide results in increased expression of BSCL2 mRNA CTD PMID:22003191, PMID:25270620 NCBI chr 1:225,035,956...225,046,137
Ensembl chr 1:225,037,737...225,046,040
JBrowse link
G Btg2 BTG anti-proliferation factor 2 multiple interactions
increases expression
ISO TRP53 protein affects the reaction [Etoposide results in increased expression of BTG2 mRNA]
TP53 promotes the reaction [Etoposide results in increased expression of BTG2 protein]
Etoposide results in increased expression of BTG2 mRNA; Etoposide results in increased expression of BTG2 protein
CTD PMID:21382384, PMID:22003191, PMID:24211769, PMID:27358234 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Btg3 BTG anti-proliferation factor 3 decreases expression ISO Etoposide results in decreased expression of BTG3 mRNA CTD PMID:24211769 NCBI chr11:16,873,642...16,889,100
Ensembl chr11:16,873,646...16,889,201
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase decreases expression ISO Etoposide results in decreased expression of BUB1 mRNA CTD PMID:16120219 NCBI chr 3:120,373,604...120,404,910
Ensembl chr 3:120,373,604...120,404,910
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B decreases expression ISO Etoposide results in decreased expression of BUB1B mRNA CTD PMID:16120219 NCBI chr 3:110,367,949...110,420,471
Ensembl chr 3:110,367,939...110,420,458
JBrowse link
G C1qbp complement C1q binding protein decreases response to substance ISO C1QBP protein results in decreased susceptibility to Etoposide CTD PMID:25354864 NCBI chr10:57,613,876...57,618,527
Ensembl chr10:57,613,879...57,618,527
JBrowse link
G Cab39 calcium binding protein 39 decreases expression ISO Etoposide results in decreased expression of CAB39 mRNA CTD PMID:17374387 NCBI chr 9:92,834,327...92,895,778
Ensembl chr 9:92,834,357...92,895,778
JBrowse link
G Cadps2 calcium dependent secretion activator 2 affects response to substance ISO CADPS2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:50,326,447...50,861,161
Ensembl chr 4:50,326,442...50,860,756
JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions
decreases response to substance
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [CALCA protein results in decreased susceptibility to Etoposide] CTD PMID:16222118 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
JBrowse link
G Calm1 calmodulin 1 increases expression ISO Etoposide results in increased expression of CALM1 mRNA CTD PMID:29397400 NCBI chr 6:124,217,241...124,225,292
Ensembl chr 6:124,217,241...124,225,292
JBrowse link
G Card10 caspase recruitment domain family, member 10 multiple interactions
increases expression
ISO Estradiol inhibits the reaction [Etoposide results in increased expression of CARD10 mRNA] CTD PMID:19426747 NCBI chr 7:119,998,639...120,028,632
Ensembl chr 7:119,999,472...120,027,026
JBrowse link
G Casp2 caspase 2 increases expression
increases splicing
ISO Etoposide results in increased expression of CASP2 mRNA alternative form
Etoposide results in increased splicing of CASP2 mRNA
CTD PMID:14757846 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239
JBrowse link
G Casp3 caspase 3 affects expression
increases cleavage
multiple interactions
increases activity
increases expression
ISO
EXP
Etoposide affects the expression of CASP3 protein
Etoposide results in increased cleavage of CASP3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; 3',4'-dihydroxyflavone analog inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of CASP3 protein]; [Etoposide co-treated with Mifepristone] results in increased activity of CASP3 protein; [RASSF1 co-treated with Etoposide] results in increased cleavage of CASP3 protein; [STAT1 protein results in increased activity of CASP3 protein] which results in increased susceptibility to Etoposide; Acetylcysteine inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; Aspirin inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; BCL2 protein inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; BCL2L1 protein inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; CASP8 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; CD40LG protein inhibits the reaction [Etoposide promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]; CDKN1A mutant form inhibits the reaction [Aspirin inhibits the reaction [Etoposide results in increased activity of CASP3 protein]]; Dehydroascorbic Acid promotes the reaction [Etoposide results in increased activity of CASP3 protein]; Etoposide promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]; Etoposide promotes the reaction [Gold results in increased activity of CASP3 protein]; Etoposide promotes the reaction [Nanotubes, Carbon results in increased activity of CASP3 protein]; Etoposide promotes the reaction [Silver results in increased activity of CASP3 protein]; Etoposide results in increased cleavage of and results in increased activity of CASP3 protein; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; nimesulide inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; Oxygen deficiency inhibits the reaction [Etoposide results in increased expression of CASP3 protein]; palbociclib inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; pifithrin promotes the reaction [Etoposide results in increased activity of CASP3 protein]; pifithrin promotes the reaction [Etoposide results in increased cleavage of CASP3 protein]; Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; TMSB4X protein inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; TP73 mutant form inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; TP73 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; Wortmannin promotes the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP3 protein]
[Etoposide results in increased activity of GSK3B protein] which results in increased activity of CASP3 protein; Etoposide results in increased activity of CASP3 protein
2-tert-butylhydroquinone inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP3 protein]; BCL2 protein affects the reaction [[Etoposide results in increased activity of GSK3B protein] which results in increased activity of CASP3 protein]; Etoposide results in increased cleavage of and results in increased activity of CASP3 protein; HIPK2 gene mutant form promotes the reaction [Etoposide results in increased activity of CASP3 protein]; Metoclopramide inhibits the reaction [Etoposide results in increased activity of CASP3 protein]
CTD PMID:8840993, PMID:10759716, PMID:12871656, PMID:15215046, PMID:15924153, PMID:16014620, PMID:16192531, PMID:16364925, PMID:16545138, PMID:16844113, PMID:16951922, PMID:17516866, PMID:17935137, PMID:18056177, PMID:18649362, PMID:19047049, PMID:19408126, PMID:19662097, PMID:19760634, PMID:20299546, PMID:20573984, PMID:21617849, PMID:21745461, PMID:21745629, PMID:21801448, PMID:21880625, PMID:22275372, PMID:22302033, PMID:23144690, PMID:25447644, PMID:26259609, PMID:29027213, PMID:30217652, PMID:30890322 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 multiple interactions
increases activity
ISO [STAT1 protein results in increased activity of CASP7 protein] which results in increased susceptibility to Etoposide; benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [Etoposide results in increased activity of CASP7 protein]; palbociclib inhibits the reaction [Etoposide results in increased activity of CASP7 protein]; pifithrin promotes the reaction [Etoposide results in increased activity of CASP7 protein]; Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased activity of CASP7 protein]; TP73 mutant form inhibits the reaction [Etoposide results in increased activity of CASP7 protein]
2-tert-butylhydroquinone inhibits the reaction [Etoposide results in increased activity of CASP7 protein]
CTD PMID:18056177, PMID:18649362, PMID:20299546, PMID:21801448, PMID:22275372, PMID:22302033, PMID:26259609 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 multiple interactions
increases response to substance
increases cleavage
increases activity
decreases response to substance
ISO 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [Etoposide results in increased activity of CASP8 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of CASP3 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of PARP1 protein]; [CASP8 co-treated with TP53] inhibits the reaction [CASP8 protein mutant form results in decreased susceptibility to Etoposide]; acetyl-leucyl-glutamyl-histidyl-aspartal inhibits the reaction [Etoposide results in increased activity of CASP8 protein]; CASP8 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; CASP8 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP9 protein]; Etoposide results in increased cleavage of and results in increased activity of CASP8 protein; Etoposide results in increased expression of and results in increased cleavage of CASP8 protein; Lithium inhibits the reaction [Etoposide results in increased activity of CASP8 protein]; nimesulide inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP8 protein]; TP73 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP8 protein]
CASP8 protein results in increased susceptibility to Etoposide
CTD PMID:15475000, PMID:21745461, PMID:21801448, PMID:22010212 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage
increases activity
affects expression
ISO [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]; [Cisplatin co-treated with Etoposide] results in increased activity of CASP9 protein; CASP8 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP9 protein]; CASP9 mutant form inhibits the reaction [Etoposide results in increased cleavage of BID protein]; Etoposide results in increased cleavage of and results in increased activity of CASP9 protein; HTATIP2 protein promotes the reaction [Etoposide results in increased activity of CASP9 protein]; MYC protein promotes the reaction [Etoposide results in increased cleavage of CASP9 protein]; Nicotine inhibits the reaction [[Cisplatin co-treated with Etoposide] results in increased activity of CASP9 protein]; nimesulide inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]; TMSB4X protein inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]; Wortmannin promotes the reaction [Etoposide results in increased cleavage of CASP9 protein]
Etoposide affects the expression of CASP9 protein
CTD PMID:12925536, PMID:15215046, PMID:16364925, PMID:16799960, PMID:17935137, PMID:18056177, PMID:18676776, PMID:21324178, PMID:21745461, PMID:21801448 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Casq2 calsequestrin 2 decreases expression ISO Etoposide results in decreased expression of CASQ2 mRNA CTD PMID:29397400 NCBI chr 2:204,512,361...204,568,643
Ensembl chr 2:204,512,302...204,568,656
JBrowse link
G Cast calpastatin multiple interactions ISO CAST inhibits the reaction [Etoposide results in increased degradation of AR protein] CTD PMID:18726991 NCBI chr 2:1,452,111...1,561,669
Ensembl chr 2:1,452,116...1,561,464
JBrowse link
G Cat catalase increases response to substance
increases activity
ISO CAT results in increased susceptibility to Etoposide
Etoposide results in increased activity of CAT protein
CTD PMID:21689642, PMID:25451571 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccdc51 coiled-coil domain containing 51 decreases expression ISO Etoposide results in decreased expression of CCDC51 mRNA CTD PMID:24211769 NCBI chr 8:117,812,091...117,830,848
Ensembl chr 8:117,812,099...117,830,868
JBrowse link
G Ccdc6 coiled-coil domain containing 6 increases response to substance
decreases response to substance
ISO CCDC6 results in increased susceptibility to Etoposide
CCDC6 results in decreased susceptibility to Etoposide
CTD PMID:22363533, PMID:22655027 NCBI chr20:19,729,005...19,825,219
Ensembl chr20:19,732,894...19,825,150
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression ISO Etoposide results in increased expression of CCL3 protein CTD PMID:10540334 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccn2 cellular communication network factor 2 increases expression ISO Etoposide results in increased expression of CCN2 mRNA CTD PMID:29397400 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccna2 cyclin A2 multiple interactions
decreases expression
ISO Etoposide affects the expression of and affects the localization of CCNA2 protein
Etoposide results in decreased expression of CCNA2 mRNA; Etoposide results in decreased expression of CCNA2 protein
CTD PMID:16120219, PMID:17390037 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO Etoposide results in decreased expression of CCNB1 mRNA; Etoposide results in decreased expression of CCNB1 protein CTD PMID:16120219 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO Etoposide results in increased expression of CCND1 mRNA CTD PMID:16120219 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccng1 cyclin G1 increases expression ISO Etoposide results in increased expression of CCNG1 mRNA CTD PMID:25270620 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325
JBrowse link
G Ccng2 cyclin G2 increases expression ISO Etoposide results in increased expression of CCNG2 mRNA CTD PMID:18754885 NCBI chr14:16,267,572...16,276,068
Ensembl chr14:16,267,573...16,276,068
JBrowse link
G Ccs copper chaperone for superoxide dismutase increases expression ISO Etoposide results in increased expression of CCS mRNA CTD PMID:21527772 NCBI chr 1:220,075,251...220,096,319
Ensembl chr 1:220,075,247...220,096,404
JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of CCT8 protein CTD PMID:29733421 NCBI chr11:27,130,172...27,141,881
Ensembl chr11:27,130,172...27,141,881
JBrowse link
G Cd274 CD274 molecule increases expression ISO Etoposide results in increased expression of CD274 protein CTD PMID:17920123 NCBI chr 1:247,519,890...247,539,659
Ensembl chr 1:247,519,939...247,537,943