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ONTOLOGY REPORT - ANNOTATIONS


Term:nicotinic acid
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Accession:CHEBI:15940 term browser browse the term
Definition:A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.
Synonyms:related_synonym: 3-Pyridinecarboxylic acid;   3-Pyridylcarboxylic acid;   3-carboxypyridine;   Formula=C6H5NO2;   InChI=1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9);   InChIKey=PVNIIMVLHYAWGP-UHFFFAOYSA-N;   Niacin;   Nikotinsaeure;   P.P. factor;   PP factor;   SMILES=OC(=O)c1cccnc1;   acide nicotinique;   acido nicotinico;   acidum nicotinicum;   anti-pellagra vitamin;   beta-pyridinecarboxylic acid;   m-pyridinecarboxylic acid;   pellagra preventive factor;   pyridine-3-carboxylic acid;   pyridine-beta-carboxylic acid;   vitamin B3
 alt_id: CHEBI:25538;   CHEBI:44319;   CHEBI:7559
 xref: Beilstein:109591 "Beilstein";   CAS:59-67-6 "ChemIDplus";   CAS:59-67-6 "KEGG COMPOUND";   CAS:59-67-6 "NIST Chemistry WebBook";   DrugBank:DB00627;   Drug_Central:2835 "DrugCentral";   Gmelin:3340 "Gmelin";   HMDB:HMDB0001488;   KEGG:C00253;   KEGG:D00049;   KNApSAcK:C00000208;   LINCS:LSM-4676
 xref_mesh: MESH:D009525
 xref: MetaCyc:NIACINE;   PDBeChem:NIO;   PMID:12563315 "Europe PMC";   PMID:12789870 "Europe PMC";   PMID:15037193 "Europe PMC";   PMID:15183629 "Europe PMC";   PMID:15205990 "Europe PMC";   PMID:15311728 "Europe PMC";   PMID:15627518 "Europe PMC";   PMID:16018787 "Europe PMC";   PMID:16172771 "Europe PMC";   PMID:16400392 "Europe PMC";   PMID:16449845 "Europe PMC";   PMID:16767301 "Europe PMC";   PMID:16877271 "Europe PMC";   PMID:16945375 "Europe PMC";   PMID:18037924 "Europe PMC";   PMID:18993152 "Europe PMC";   PMID:18996527 "Europe PMC";   PMID:19369827 "Europe PMC";   PMID:19592242 "Europe PMC";   PMID:19678716 "Europe PMC";   PMID:19779335 "Europe PMC";   PMID:20979384 "Europe PMC";   PMID:21632263 "Europe PMC";   PMID:22116693 "Europe PMC";   PMID:22155410 "Europe PMC";   PMID:22229411 "Europe PMC";   PMID:22366213 "Europe PMC";   PMID:22458880 "Europe PMC";   PMID:22770225 "Europe PMC";   PMID:24568240 "Europe PMC";   PMID:24675661 "Europe PMC";   PMID:24848081 "Europe PMC";   PMID:24975217 "Europe PMC";   PMID:25040591 "Europe PMC";   PMID:25241762 "Europe PMC";   PMID:25429652 "Europe PMC";   PMID:4259917 "Europe PMC";   Reaxys:109591 "Reaxys";   Wikipedia:Niacin
 cyclic_relationship: is_conjugate_acid_of CHEBI:32544


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nicotinic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abca1 ATP binding cassette subfamily A member 1 JBrowse link 5 69,857,717 69,983,042 RGD:6480464
G Abcg1 ATP binding cassette subfamily G member 1 JBrowse link 20 9,743,269 9,842,735 RGD:6480464
G Ace angiotensin I converting enzyme JBrowse link 10 94,170,766 94,213,831 RGD:6480464
G Acmsd aminocarboxymuconate semialdehyde decarboxylase JBrowse link 13 44,424,689 44,468,734 RGD:6480464
G Adam17 ADAM metallopeptidase domain 17 JBrowse link 6 43,400,525 43,448,280 RGD:6480464
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:6480464
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:6480464
G Ahsg alpha-2-HS-glycoprotein JBrowse link 11 81,711,269 81,717,594 RGD:6480464
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Angpt1 angiopoietin 1 JBrowse link 7 81,338,327 81,592,459 RGD:6480464
G Angpt2 angiopoietin 2 JBrowse link 16 75,966,480 76,016,147 RGD:6480464
G Apoa1 apolipoprotein A1 JBrowse link 8 50,525,091 50,526,875 RGD:6480464
G Apob apolipoprotein B JBrowse link 6 33,176,826 33,216,381 RGD:6480464
G Arhgap8 Rho GTPase activating protein 8 JBrowse link 7 125,732,300 125,797,149 RGD:6480464
G Asph aspartate-beta-hydroxylase JBrowse link 5 22,577,680 22,799,333 RGD:6480464
G Atp5f1b ATP synthase F1 subunit beta JBrowse link 7 2,504,708 2,511,748 RGD:6480464
G Bdnf brain-derived neurotrophic factor JBrowse link 3 100,768,637 100,819,216 RGD:6480464
G Btc betacellulin JBrowse link 14 18,231,854 18,270,621 RGD:6480464
G Casq1 calsequestrin 1 JBrowse link 13 90,592,676 90,602,365 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:6480464
G Cav3 caveolin 3 JBrowse link 4 144,382,945 144,398,919 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Cebpa CCAAT/enhancer binding protein alpha JBrowse link 1 91,363,492 91,366,164 RGD:6480464
G Cebpb CCAAT/enhancer binding protein beta JBrowse link 3 164,424,502 164,425,933 RGD:6480464
G Cebpd CCAAT/enhancer binding protein delta JBrowse link 11 89,008,008 89,009,146 RGD:6480464
G Cert1 ceramide transporter 1 JBrowse link 2 27,365,145 27,469,797 RGD:6480464
G Chn2 chimerin 2 JBrowse link 4 84,423,708 84,452,989 RGD:6480464
G Cidea cell death-inducing DFFA-like effector a JBrowse link 18 63,082,861 63,108,450 RGD:6480464
G Cpt2 carnitine palmitoyltransferase 2 JBrowse link 5 127,505,646 127,523,016 RGD:6480464
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:6480464
G Cst11 cystatin 11 JBrowse link 3 143,096,056 143,098,780 RGD:6480464
G Cst8 cystatin 8 JBrowse link 3 143,129,240 143,141,000 RGD:6480464
G Cyba cytochrome b-245 alpha chain JBrowse link 19 55,249,634 55,257,824 RGD:6480464
G Ddhd1 DDHD domain containing 1 JBrowse link 15 19,963,639 20,032,263 RGD:6480464
G Dgat2 diacylglycerol O-acyltransferase 2 JBrowse link 1 164,113,459 164,143,818 RGD:6480464
G Dusp5 dual specificity phosphatase 5 JBrowse link 1 274,245,184 274,258,595 RGD:6480464
G Ecel1 endothelin converting enzyme-like 1 JBrowse link 9 94,238,568 94,252,484 RGD:6480464
G Ednrb endothelin receptor type B JBrowse link 15 88,004,775 88,036,354 RGD:6480464
G Egr2 early growth response 2 JBrowse link 20 22,452,170 22,461,018 RGD:6480464
G Eif2a eukaryotic translation initiation factor 2A JBrowse link 2 148,722,343 148,755,781 RGD:6480464
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 JBrowse link 16 68,954,860 68,968,248 RGD:6480464
G Eno3 enolase 3 JBrowse link 10 57,278,271 57,283,661 RGD:6480464
G F2r coagulation factor II (thrombin) receptor JBrowse link 2 26,118,760 26,135,340 RGD:6480464
G Fabp1 fatty acid binding protein 1 JBrowse link 4 99,063,181 99,066,957 RGD:6480464
G Fabp4 fatty acid binding protein 4 JBrowse link 2 93,792,666 93,797,267 RGD:6480464
G Fasn fatty acid synthase JBrowse link 10 109,987,735 110,005,901 RGD:6480464
G Foxo1 forkhead box O1 JBrowse link 2 141,451,234 141,527,016 RGD:6480464
G Gcg glucagon JBrowse link 3 48,442,635 48,451,650 RGD:6480464
G Ggt1 gamma-glutamyltransferase 1 JBrowse link 20 14,019,723 14,045,781 RGD:6480464
G Gh1 growth hormone 1 JBrowse link 10 94,486,204 94,488,181 RGD:6480464
G Gpd1 glycerol-3-phosphate dehydrogenase 1 JBrowse link 7 141,368,928 141,377,931 RGD:6480464
G Gpi glucose-6-phosphate isomerase JBrowse link 1 90,063,411 90,091,287 RGD:6480464
G Hcar2 hydroxycarboxylic acid receptor 2 JBrowse link 12 38,160,464 38,161,546 RGD:6480464
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Hspb1 heat shock protein family B (small) member 1 JBrowse link 12 23,839,390 23,841,051 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:6480464
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Kdr kinase insert domain receptor JBrowse link 14 34,727,677 34,787,127 RGD:6480464
G Kras KRAS proto-oncogene, GTPase JBrowse link 4 179,482,562 179,515,483 RGD:6480464
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:6480464
G Lepr leptin receptor JBrowse link 5 120,503,475 120,682,281 RGD:6480464
G Lipe lipase E, hormone sensitive type JBrowse link 1 82,248,031 82,266,727 RGD:6480464
G Litaf lipopolysaccharide-induced TNF factor JBrowse link 10 4,753,546 4,763,272 RGD:6480464
G Map2 microtubule-associated protein 2 JBrowse link 9 73,204,753 73,462,965 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mlxipl MLX interacting protein-like JBrowse link 12 24,590,645 24,619,639 RGD:6480464
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:6480464
G Ncf1 neutrophil cytosolic factor 1 JBrowse link 12 25,497,104 25,506,300 RGD:6480464
G Net1 neuroepithelial cell transforming 1 JBrowse link 17 69,991,786 70,020,977 RGD:6480464
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:6480464
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:6480464
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:6480464
G Nox4 NADPH oxidase 4 JBrowse link 1 150,796,359 150,976,186 RGD:6480464
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 JBrowse link 3 80,004,130 80,014,197 RGD:6480464
G Nrap nebulin-related anchoring protein JBrowse link 1 277,104,519 277,181,397 RGD:6480464
G Ntrk2 neurotrophic receptor tyrosine kinase 2 JBrowse link 17 5,934,651 6,245,778 RGD:6480464
G Olr1 oxidized low density lipoprotein receptor 1 JBrowse link 4 163,239,853 163,261,937 RGD:6480464
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:6480464
G Pck1 phosphoenolpyruvate carboxykinase 1 JBrowse link 3 171,213,936 171,219,885 RGD:6480464
G Pdk4 pyruvate dehydrogenase kinase 4 JBrowse link 4 30,546,772 30,556,774 RGD:6480464
G Pecam1 platelet and endothelial cell adhesion molecule 1 JBrowse link 10 94,850,971 94,913,202 RGD:6480464
G Pi16 peptidase inhibitor 16 JBrowse link 20 6,923,176 6,932,786 RGD:6480464
G Pla2g7 phospholipase A2 group VII JBrowse link 9 19,935,754 19,978,013 RGD:6480464
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 7 126,618,872 126,687,282 RGD:6480464
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:6480464
G Ppargc1a PPARG coactivator 1 alpha JBrowse link 14 63,095,291 63,190,688 RGD:6480464
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 JBrowse link 5 124,568,845 124,642,569 RGD:6480464
G Ptgdr prostaglandin D2 receptor JBrowse link 15 19,195,606 19,196,508 RGD:6480464
G Ptgds prostaglandin D2 synthase JBrowse link 3 2,686,125 2,689,059 RGD:6480464
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Qprt quinolinate phosphoribosyltransferase JBrowse link 1 198,544,262 198,559,556 RGD:6480464
G Ralgapa1 Ral GTPase activating protein catalytic alpha subunit 1 JBrowse link 6 76,386,971 76,661,530 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Retn resistin JBrowse link 12 2,201,909 2,203,649 RGD:6480464
G Rps6kb1 ribosomal protein S6 kinase B1 JBrowse link 10 73,824,200 73,865,503 RGD:6480464
G Rtn4r reticulon 4 receptor JBrowse link 11 86,992,665 87,017,091 RGD:6480464
G Scarb1 scavenger receptor class B, member 1 JBrowse link 12 36,694,952 36,761,445 RGD:6480464
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:6480464
G Sirt2 sirtuin 2 JBrowse link 1 86,948,866 86,971,954 RGD:6480464
G Sirt4 sirtuin 4 JBrowse link 12 46,862,358 46,876,593 RGD:6480464
G Slc16a1 solute carrier family 16 member 1 JBrowse link 2 207,108,552 207,129,352 RGD:6480464
G Slc22a7 solute carrier family 22 member 7 JBrowse link 9 16,925,321 16,931,119 RGD:6480464
G Slc27a2 solute carrier family 27 member 2 JBrowse link 3 119,014,620 119,052,531 RGD:6480464
G Slc27a4 solute carrier family 27 member 4 JBrowse link 3 8,363,937 8,376,858 RGD:6480464
G Slc2a4 solute carrier family 2 member 4 JBrowse link 10 56,552,921 56,558,562 RGD:6480464
G Slc4a2 solute carrier family 4 member 2 JBrowse link 4 7,264,677 7,282,355 RGD:6480464
G Spink5 serine peptidase inhibitor, Kazal type 5 JBrowse link 18 35,118,300 35,190,458 RGD:6480464
G Srl sarcalumenin JBrowse link 10 11,240,135 11,284,325 RGD:6480464
G St6gal1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 JBrowse link 11 80,927,601 80,981,424 RGD:6480464
G Star steroidogenic acute regulatory protein JBrowse link 16 71,036,204 71,040,847 RGD:6480464
G Stat5a signal transducer and activator of transcription 5A JBrowse link 10 88,764,732 88,789,060 RGD:6480464
G Syp synaptophysin JBrowse link X 15,694,699 15,709,244 RGD:6480464
G Tek TEK receptor tyrosine kinase JBrowse link 5 113,725,717 113,852,799 RGD:6480464
G Tesc tescalcin JBrowse link 12 44,141,258 44,174,701 RGD:6480464
G Tfrc transferrin receptor JBrowse link 11 71,397,423 71,419,263 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:6480464
G Tln1 talin 1 JBrowse link 5 59,033,635 59,063,592 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464
G Tpm1 tropomyosin 1 JBrowse link 8 72,814,737 72,841,496 RGD:6480464
G Ttpa alpha tocopherol transfer protein JBrowse link 5 34,007,926 34,029,315 RGD:6480464
G Ucp1 uncoupling protein 1 JBrowse link 19 24,456,976 24,464,808 RGD:6480464
G Vcam1 vascular cell adhesion molecule 1 JBrowse link 2 219,071,193 219,090,931 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:6480464
G Vtn vitronectin JBrowse link 10 65,767,960 65,771,040 RGD:6480464
1-methylnicotinamide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dek DEK proto-oncogene JBrowse link 17 17,965,872 17,987,836 RGD:6480464
G Lepr leptin receptor JBrowse link 5 120,503,475 120,682,281 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Slc22a1 solute carrier family 22 member 1 JBrowse link 1 48,273,639 48,300,645 RGD:6480464
G Slc22a16 solute carrier family 22 member 16 JBrowse link 20 45,658,398 45,669,192 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464
6-aminonicotinamide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf2 fibroblast growth factor 2 JBrowse link 2 124,081,072 124,134,133 RGD:6480464
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Mt1 metallothionein 1 JBrowse link 19 11,301,991 11,303,007 RGD:6480464
G Mt2A metallothionein 2A JBrowse link 19 11,307,966 11,308,740 RGD:6480464
G Mt3 metallothionein 3 JBrowse link 19 11,324,708 11,326,112 RGD:6480464
G Ntf3 neurotrophin 3 JBrowse link 4 158,636,883 158,705,886 RGD:6480464
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:6480464
G Sox17 SRY-box transcription factor 17 JBrowse link 5 14,890,318 14,895,907 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
flunixin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:6480464
N-methylnicotinamide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 JBrowse link 1 141,874,354 141,893,674 RGD:6480464
G Slco1a4 solute carrier organic anion transporter family, member 1a4 JBrowse link 4 175,969,549 176,026,227 RGD:6480464
N-ribosylnicotinamide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc6 ERCC excision repair 6, chromatin remodeling factor JBrowse link 16 8,734,028 8,804,610 RGD:6480464
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 JBrowse link 17 32,131,847 32,158,559 RGD:6480464
nicorandil term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc9 ATP binding cassette subfamily C member 9 JBrowse link 4 176,806,098 176,928,540 RGD:6480464
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:6480464
G Ctsd cathepsin D JBrowse link 1 215,541,570 215,553,446 RGD:6480464
G Gal galanin and GMAP prepropeptide JBrowse link 1 218,653,059 218,657,922 RGD:6480464
G Gusb glucuronidase, beta JBrowse link 12 30,202,066 30,215,583 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:6480464
G Xdh xanthine dehydrogenase JBrowse link 6 25,149,570 25,211,273 RGD:6480464
nicotinamide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acaca acetyl-CoA carboxylase alpha JBrowse link 10 71,519,392 71,719,910 RGD:6480464
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:6480464
G Ago2 argonaute RISC catalytic component 2 JBrowse link 7 114,339,607 114,377,277 RGD:6480464
G Agtr1a angiotensin II receptor, type 1a JBrowse link 17 35,907,102 35,958,136 RGD:6480464
G Apaf1 apoptotic peptidase activating factor 1 JBrowse link 7 31,699,309 31,784,192 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bbc3 Bcl-2 binding component 3 JBrowse link 1 78,261,491 78,267,802 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Bcl2l11 BCL2 like 11 JBrowse link 3 120,726,906 120,764,192 RGD:6480464
G Bmi1 BMI1 proto-oncogene, polycomb ring finger JBrowse link 17 85,360,439 85,370,283 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Ccl20 C-C motif chemokine ligand 20 JBrowse link 9 88,918,359 88,921,017 RGD:6480464
G Cd38 CD38 molecule JBrowse link 14 71,714,768 71,754,990 RGD:6480464
G Cd40 CD40 molecule JBrowse link 3 161,519,789 161,534,943 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 4 168,689,043 168,694,159 RGD:6480464
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:6480464
G Chuk component of inhibitor of nuclear factor kappa B kinase complex JBrowse link 1 263,848,829 263,884,354 RGD:6480464
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:6480464
G Col1a2 collagen type I alpha 2 chain JBrowse link 4 31,534,225 31,569,152 RGD:6480464
G Cyba cytochrome b-245 alpha chain JBrowse link 19 55,249,634 55,257,824 RGD:6480464
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:6480464
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 JBrowse link 12 11,641,500 11,677,818 RGD:6480464
G Defb4 defensin beta 4 JBrowse link 16 75,634,598 75,637,789 RGD:6480464
G Dicer1 dicer 1 ribonuclease III JBrowse link 6 128,388,084 128,453,234 RGD:6480464
G Dlg1 discs large MAGUK scaffold protein 1 JBrowse link 11 72,164,566 72,378,895 RGD:6480464
G Dnmt1 DNA methyltransferase 1 JBrowse link 8 21,922,515 21,968,495 RGD:6480464
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 JBrowse link 16 68,954,860 68,968,248 RGD:6480464
G Ercc6 ERCC excision repair 6, chromatin remodeling factor JBrowse link 16 8,734,028 8,804,610 RGD:6480464
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:6480464
G Faslg Fas ligand JBrowse link 13 79,696,811 79,717,581 RGD:6480464
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6480464
G Foxo1 forkhead box O1 JBrowse link 2 141,451,234 141,527,016 RGD:6480464
G Foxo3 forkhead box O3 JBrowse link 20 46,428,078 46,519,156 RGD:6480464
G G6pc glucose-6-phosphatase, catalytic subunit JBrowse link 10 89,286,009 89,296,213 RGD:6480464
G G6pd glucose-6-phosphate dehydrogenase JBrowse link X 156,274,800 156,293,935 RGD:6480464
G Gcg glucagon JBrowse link 3 48,442,635 48,451,650 RGD:6480464
G Gclc glutamate-cysteine ligase, catalytic subunit JBrowse link 8 85,059,051 85,097,471 RGD:6480464
G Glb1 galactosidase, beta 1 JBrowse link 8 122,439,328 122,511,939 RGD:6480464
G Glo1 glyoxalase 1 JBrowse link 20 9,273,589 9,291,608 RGD:6480464
G Gsr glutathione-disulfide reductase JBrowse link 16 62,197,617 62,239,987 RGD:6480464
G Gstm5 glutathione S-transferase, mu 5 JBrowse link 2 210,685,338 210,688,133 RGD:6480464
G Gys2 glycogen synthase 2 JBrowse link 4 176,638,632 176,679,805 RGD:6480464
G Hba-a2 hemoglobin alpha, adult chain 2 JBrowse link 10 15,589,364 15,590,207 RGD:6480464
G Hdac1 histone deacetylase 1 JBrowse link 5 147,716,664 147,743,723 RGD:6480464
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 2 27,480,224 27,500,654 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:6480464
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:6480464
G Igfbp1 insulin-like growth factor binding protein 1 JBrowse link 14 87,448,716 87,453,783 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:6480464
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:6480464
G Keap1 Kelch-like ECH-associated protein 1 JBrowse link 8 22,250,518 22,259,868 RGD:6480464
G Lcat lecithin cholesterol acyltransferase JBrowse link 19 37,913,333 37,916,799 RGD:6480464
G Lpl lipoprotein lipase JBrowse link 16 22,537,687 22,561,487 RGD:6480464
G Mafa MAF bZIP transcription factor A JBrowse link 7 116,779,368 116,781,815 RGD:6480464
G Map1lc3b microtubule-associated protein 1 light chain 3 beta JBrowse link 19 53,635,449 53,643,970 RGD:6480464
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:6480464
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:6480464
G Mir3545 microRNA 3545 JBrowse link 6 136,704,947 136,705,061 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:6480464
G Msra methionine sulfoxide reductase A JBrowse link 15 47,488,333 47,800,662 RGD:6480464
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:6480464
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:6480464
G Nabp2 nucleic acid binding protein 2 JBrowse link 7 2,820,006 2,825,627 RGD:6480464
G Nampt nicotinamide phosphoribosyltransferase JBrowse link 6 52,122,085 52,156,473 RGD:6480464
G Ncor1 nuclear receptor co-repressor 1 JBrowse link 10 48,629,121 48,772,890 RGD:6480464
G Ndufa1 NADH:ubiquinone oxidoreductase subunit A1 JBrowse link X 123,803,109 123,806,760 RGD:6480464
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 JBrowse link 16 21,275,311 21,282,246 RGD:6480464
G Ndufa2 NADH:ubiquinone oxidoreductase subunit A2 JBrowse link 18 29,585,671 29,587,760 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Nox4 NADPH oxidase 4 JBrowse link 1 150,796,359 150,976,186 RGD:6480464
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 JBrowse link 7 142,899,358 142,920,216 RGD:6480464
G Ogdh oxoglutarate dehydrogenase JBrowse link 14 86,414,924 86,481,903 RGD:6480464
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:6480464
G Pdk4 pyruvate dehydrogenase kinase 4 JBrowse link 4 30,546,772 30,556,774 RGD:6480464
G Pdp1 pyruvate dehyrogenase phosphatase catalytic subunit 1 JBrowse link 5 25,577,593 25,584,325 RGD:6480464
G Pitx2 paired-like homeodomain 2 JBrowse link 2 233,602,732 233,621,059 RGD:6480464
G Pmp22 peripheral myelin protein 22 JBrowse link 10 49,538,588 49,568,583 RGD:6480464
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:6480464
G Ppargc1a PPARG coactivator 1 alpha JBrowse link 14 63,095,291 63,190,688 RGD:6480464
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 JBrowse link 2 54,857,688 54,893,404 RGD:6480464
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 JBrowse link 5 124,568,845 124,642,569 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Pygl glycogen phosphorylase L JBrowse link 6 92,597,759 92,643,734 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Rps6 ribosomal protein S6 JBrowse link 5 105,197,821 105,200,681 RGD:6480464
G Runx2 RUNX family transcription factor 2 JBrowse link 9 18,564,743 18,773,092 RGD:6480464
G Shc1 SHC adaptor protein 1 JBrowse link 2 188,745,503 188,757,066 RGD:6480464
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:6480464
G Sirt2 sirtuin 2 JBrowse link 1 86,948,866 86,971,954 RGD:6480464
G Sirt3 sirtuin 3 JBrowse link 1 213,613,502 213,636,061 RGD:6480464
G Slco1a4 solute carrier organic anion transporter family, member 1a4 JBrowse link 4 175,969,549 176,026,227 RGD:6480464
G Snap23 synaptosome associated protein 23 JBrowse link 3 112,333,972 112,362,960 RGD:6480464
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:6480464
G Sox9 SRY-box transcription factor 9 JBrowse link 10 101,288,528 101,294,030 RGD:6480464
G Sqstm1 sequestosome 1 JBrowse link 10 35,704,728 35,716,316 RGD:6480464
G Srebf1 sterol regulatory element binding transcription factor 1 JBrowse link 10 46,570,996 46,593,021 RGD:6480464
G Stx4 syntaxin 4 JBrowse link 1 199,287,384 199,295,606 RGD:6480464
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Tnfrsf11b TNF receptor superfamily member 11B JBrowse link 7 93,798,580 93,826,586 RGD:6480464
G Tnfsf11 TNF superfamily member 11 JBrowse link 15 60,482,527 60,512,704 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464
G Ucp2 uncoupling protein 2 JBrowse link 1 165,506,375 165,512,744 RGD:6480464
G Vamp2 vesicle-associated membrane protein 2 JBrowse link 10 55,675,171 55,679,405 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        biochemical role 19138
          metabolite 19106
            nicotinic acid 239
              1,4,5,6-tetrahydro-6-oxonicotinic acid 0
              2,6-dihydroxynicotinic acid 0
              2-aminonicotinic acid 0
              4-aminonicotinic acid 0
              4-methoxy-1-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid 0
              5-aminonicotinic acid 0
              5-hydroxy-6-methylpyridine-3-carboxylic acid 0
              5-pyridoxic acid + 0
              6-aminonicotinic acid + 13
              6-hydroxynicotinic acid 0
              D-ribosylnicotinic acid + 0
              Euphorbia diterpenoid 2 0
              N-methylnicotinic acid 0
              benzyl nicotinate 0
              boscalid + 0
              clonixin 0
              cyclitol nicotinate + 0
              flunixin 1
              hyponine D 0
              hyponine E 0
              inositol hexanicotinate + 0
              myo-inositol hexanicotinate 0
              nicotinamide + 125
              regelidine 0
              vitamin B complex 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      carboxylic acid 17923
                                        monocarboxylic acid 17256
                                          pyridinemonocarboxylic acid 361
                                            nicotinic acid 239
                                              1,4,5,6-tetrahydro-6-oxonicotinic acid 0
                                              2,6-dihydroxynicotinic acid 0
                                              2-aminonicotinic acid 0
                                              4-aminonicotinic acid 0
                                              4-methoxy-1-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid 0
                                              5-aminonicotinic acid 0
                                              5-hydroxy-6-methylpyridine-3-carboxylic acid 0
                                              5-pyridoxic acid + 0
                                              6-aminonicotinic acid + 13
                                              6-hydroxynicotinic acid 0
                                              D-ribosylnicotinic acid + 0
                                              Euphorbia diterpenoid 2 0
                                              N-methylnicotinic acid 0
                                              benzyl nicotinate 0
                                              boscalid + 0
                                              clonixin 0
                                              cyclitol nicotinate + 0
                                              flunixin 1
                                              hyponine D 0
                                              hyponine E 0
                                              inositol hexanicotinate + 0
                                              myo-inositol hexanicotinate 0
                                              nicotinamide + 125
                                              regelidine 0
                                              vitamin B complex 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.